Computer simulated cancer treatment presented in research magazine Apollo

Arnoldo Frigessi (photo: Ola Sæther)

Researchers at the Oslo University Hospital and University of Oslo are developing a computer program that can assist oncologists to find the best personalized treatment for each patient. The main driving force behind the project is Arnoldo Frigessi, professor in medical statistics at UiO, who is head of the "Oslo Centre for Biostatistics Epidemiology" at OUS and leader of the "Centre for Research-based Innovation" (SFI) "Big Insight".

The award winning research magazine "Apollon" recently presented the work of Frigessi and collaborators in an extensive feature article by Yngve Vogt.

Nature Communications publication: How Natural Killer Cells Remember their Education

Karl-Johan Malmberg,
Senior author

A joint effort by several groups at the Institute for Cancer Research and University of Oslo, led by Dr. Jodie Goodridge and Prof. Karl-Johan Malmberg provide new insights into the molecular basis behind NK cell education.

NK cells calibrate their functional potential against host MHC in a process termed education. Paradoxically, the more inhibitory input the cell receives during its education, the stronger its functional potential. Although this phenomena is well documented and conserved across species, the cellular and molecular mechanisms underlying NK cell education have remained elusive. 

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