A basic study of the cell cycle by mass cytometry, with implications for exclusion of non-single cell events as ion cloud fusions and aggregates.
A recent study from the Sections of Core Facilities/Radiation Biology/Tumor Immunology shows that the cell cycle can be completely resolved by mass cytometry, including subdivision of the G1 and G2 phases. Only a few markers are needed, and the remaining >50 parameters are free to measure the expression of other (phospho)proteins of interest. Stratification of cells into different cell cycle phases also made exclusion of non-single cell events possible, solving another problem in mass cytometry.
