The abstract "Tailored FDG-PET protocol with prolonged acquisition and respiratory gating improves detection of metastatic lesions in the liver" was selected for Prof. Wahl's Highlight Lecture on oncology at this year's annual meeting of the Society of Nuclear Medicine and Molecular Imaging, which was held in Miami in June.
Prof. Richard Wahl is the director of the Division of Nuclear Medicine/PET at the Johns Hopkins Hospital in Baltimore, Maryland.
The abstract, which was one of in total 2152 accepted abstracts, is based on a cooperation project between the Department of Nuclear Medicine and Department of Gastrointestinal Surgery at Oslo University Hospital and is led by Mona-Elisabeth Revheim (Department of Nuclear Medicine) and Sven-Petter Haugvik (Department of Gastrointestinal Surgery).
Accurate diagnostic imaging in the preoperative assessment of patients with potentially resectable colorectal liver metastases is essential in order to decide which patients will benefit from liver surgery. Even though most hepatic colorectal metastases show increased 18F-FDG -uptake on PET imaging, the modality’s ability to detect small intrahepatic lesions has been limited by different factors. These include limited spatial resolution through the associated intensity diffusion, physiologic background activity in the liver parenchyma, possible erroneous attenuation correction and respiratory movements during acquisition
The presented study shows that for PET studies of the liver, imaging with a prolonged acquisition time and/or repeated breath-hold respiratory gating gives measurable improvements in image quality and improves detection and quantification of FDG-uptake in metastases, compared to a standard whole-body PET.
Tailored FDG-PET protocol with prolonged acquisition and respiratory gating improves detection of metastatic lesions in the liver
Revheim ME, Haugvik SP, Johnsrud K, Mathisen Ø, Giltvedt H, Spiten AE, Skretting A.
J Nucl Med. 2012 June; 53 (Supplement 1):1235