Research at Oslo University Hospital

A Norwegian research team led by Professor Johanne Olweus has developed a new and groundbreaking method that offers the possibility of treating several aggressive forms of cancer. In an article published in Nature Immunology they propose that TCR-T cells targeting CTNNB1-S37F can serve as a basis for solid cancer immunotherapy.
The results have attracted international attention, and the research was recently featured in a major article in Norway's largest newspaper VG, entitled "Norwegian cancer study: –⁠ This is definitely a breakthrough".

The National Research Conference in Musculoskeletal Health is an interdisciplinary conference that covers research in musculoskeletal injuries, diseases and ailments. The conference will be a meeting point for researchers, healthcare professionals, users, clinicians and others interested in musculoskeletal health.

Time and place: November 13-14 2025 at Clarion Hotel Oslo Airport, Gardermoen 
Deadline for abstract submission: Sept 12 (possible to apply for extended deadline)

Complete information from the conference homepage (muss.no) (in Norwegian)

The PREDI-LYNCH consortium officially launched its six-year Horizon Europe project with an in-person kickoff meeting in Heidelberg on September 18, 2025. The partners were welcomed by Project Coordinator Mev Dominguez-Valentin from the Institute for Cancer Research.
The event brought together more than 50 researchers, clinicians, and partners from across Europe. Funded under the EU Mission on Cancer, PREDI-LYNCH unites leading institutions and experts to improve screening, diagnostics, and risk prediction for individuals with a hereditary predisposition to cancer.

Julie Elisabeth Heggelund and Rasmus Iversen, both from the Department of Immunology at the Division for Laboratory Medicine (KLM), were recently awarded KLM's Career Prize for their outstanding early career research work. This award goes to researchers in the category of temporary employees, and was distributed for the first time in 2024. The evaluation committee consisted of three researchers from different KLM departments. The prize, amounting to 75.000 NOK, must be used to further research at OUS. Emma Lång, head of KLM TempAware, led the award ceremony together with her colleagues in the group, who represent the seven departments in KLM.

The National Research Archive (NVA) has replaced Cristin and is now open for both previous Cristin users and new contributors at OUS. Whether you're registering for the first time or updating your publications, NVA offers improved functionality for managing research outputs, including support for green open access and project code reporting.

Click More to learn how to get started, request editing access, and upload files for archiving.

The Norwegian-Danish BETAMI-DANBLOCK study shows that beta-blockers still provide clear health benefits after a heart attack – even in patients with normal or slightly reduced heart function. The study included over 5,600 patients who had recently had a heart attack within the past fourteen days.

Professor Dan Atar presented the results as "Hot Line" findings at the European Cardiology Congress (ESC) in Madrid (33.000 participants) on August 30 2025. At the same time, they were simultaneously published in the prestigious journals New England Journal of Medicine and The Lancet.

The article "Targeting the roots of myeloid malignancies with T cell receptors" has been published online in the prestigious journal Nature Reviews Cancer.
Senior author is Johanna Olweus, head of the Experimental Immunotherapy Group at the Department of Cancer Immunology at the Insitute for Cancer Research.

The work is a collaboration with Sten Eirik Jacobsens group at Karolinska Institutet.

Link to the article (view only version)

Researchers from the Department of Ophthalmology at OUH participated in three events at "Arendalsuka 2025" on Tuesday August 11th. Scientists Thea Melsen Sudmann, Øystein Kalsnes Jørstad, Agate Noer, Henrik Jespersen and Olav Kristianslund will give presentations on various subjects relating to eye research.

The presentations were streamed. Also available after the meeting.

Oslo University Hospital was otherwise broadly represented.

Overview day by day: events with participation from OUH researchers (August 11-15 2025).

Project leader Maja Radulovic and group leader Harald Stenmark at Department of Molecular Cell Biology, Institute for Cancer Research, have recently published a review in Nature Reviews Molecular Cell Biology entitled “Lysosomal membrane homeostasis and its importance in physiology and disease”. The motivation for this review is that lysosomes play a central role in disease progression, including neurodegenerative diseases and cancer, but also offer opportunities for novel therapies.