In a recent publication in Annals of Oncology (journal impact factor 11.9) by Jørgen Smeby and colleagues in the Lothe lab at the Department of Molecular Oncology, integration of gene expression-based subtyping and microsatellite instability status led to discovery of novel subtype-specific prognostic associations of the thoroughly investigated KRAS and BRAFV600E mutations in primary colorectal cancer (CRC).
Professor David Russell has received the prestigious Monrad-Krohns Prize for 2018 for his research contributions on diagnosis and treatment of stroke. "It is a great honor for me and a very important recognition of Norwegian research in cerebrovascular diseases," says the award winner, who is professor at UiO, and senior physician at the Department of Neurology at Oslo University Hospital, where he is heading the "Cerebrovascular diseases" research group.
Jon Amund Kyte, leader of the "Translational cancer immunotherapy" project group at the Department of Cancer Immunology at the Institute for Cancer Research, was appointed "Researcher of the Month" for February 2018 by the South-Eastern Norway Regional Health Authority (Helse Sør-Øst RHF). The group aims to develop improved cancer treatment based on two particularly promising strategies for immunotherapy. This research is presented in a feature article published on the home page of Helse Sør-Øst.
Global Engage has interviewed Guro E. Lind, group leader at the Department of Molecular Oncology.
"In order to achieve gender balance we should focus on why the system is failing recruiting the brilliant young female scientists, rather than discuss what the females should do to increase their chances of a scientific career. It is nothing wrong with our education, skill set or ambitions - it is the system that is flawed"
The Epigenetics Group at the Department of Molecular Oncology, headed by Guro E. Lind, has developed a robust internal control for DNA methylation analyses by droplet digital PCR (ddPCR). The findings have recently been published in the journal Clinical Epigenetics. First author is Heidi Dietrichson Pharo.
One of The Norwegian Research Council's three new prizes for young outstanding researchers goes to Kyrre Eeg Emblem from the Department of Diagnostic Physics at the Division of Radiology and Nuclear Medicine. Each prize is 500.000 kroner and will be distributed on March 1st.
Kyrre Eeg Emblem's research will benefit cancer patients directly. Using MRI machines, he can predict how different therapies work on people with cancer. The goal is to understand how the treatment affects the disease, and thereby predict which patients respond to the cancer treatment.
In a study published in Nature Communications on February 12th, establishment of a novel in vitro cellular assay is reported, which can be used to gain in-depth insights into how antibodies and albumin variants are transported in and out of cells, and to predict how efficiently such molecules are rescued from intracellular degradation. The assay has been coined HERA and stands for human endothelial cell-based recycling assay.
The study is based on research conducted by scientists from the Laboratory of Adaptive Immunity and Homeostasis, headed by Jan Terje Andersen, at OUH and UiO, together with several international collaborators from Harvard Medical School, The Jackson Laboratory and Roche Pharma Research and Early Development in Munich.
Ole Jacob Elle, head of the "Medical Robotics, visualisation and navigation" research group at The Intervention Centre at the Divsion of Emergencies and Critical Care has been selected as "Innovator of the Month" by the South-Eastern Norway Regional Health Authority (Helse Sør-Øst RHF). Elle's research activities and interests are presented in a popular science article (in Norwegian) entitled "Technology and health - hand in hand". He is fascinated by robots, holograms and navigation systems, and how these things can make everyday life in health care better.
Jon Michael Gran, researcher at the Oslo Centre for Biostatistics and Epidemiology (OCBE), recently received a grant of 15 million NOK from the Research Council of Norway (HELSEVEL program). The title of the project is “Effects of workplace initiatives on sick leave and work participation - new statistical and causal models to utilise population registries”. The project will utilise large linked population-wide registry data in assessing the effects of the Norwegian Agreement on a More Inclusive Working Life (the IA Agreement) and the use of graded sick leave on long-term health related absence from work.