The CCB seminar Friday March 31st will be held by Pierre Leopold, PhD, Group Leader at the Institut de Biologie Valrose, and Research Director for the National Institute of Health and Medical Research (INSERM), University of Nice.
Title of his talk: Growth coordination during development
Time and place: Friday March 31st at 12:00 PM - 01:00 PM in Seminar room 1 in the Research Building, Institute for Cancer Research, Montebello.
12:00 hrs: Growth coordination during development
Speaker: Pierre Leopold, PhD, Group Leader at the Institut de Biologie Valrose, and Research Director for the National Institute of Health and Medical Research (INSERM), University of Nice
Pierre Léopold graduated from the University of Nice and trained Drosophila developmental genetics as a post-doctoral fellow at the University of California, San Francisco (UCSF). He then obtained a CNRS starting grant to return to France where he created his own group. He has a current appointment at the University of Nice (Institute of Biology Valrose) as a Research Director for the National Institute of Health and Medical Research (INSERM). Over the recent years, he has developed a research interest for the control of tissue growth using Drosophila as a model organism. His work primarily focuses on the understanding of systemic mechanisms controlling organismal growth. This allowed to provide a dissection of organ cross-talks and molecular mechanisms orchestrating the nutritional response and the control of growth. More recently, his laboratory has demonstrated the importance of organ-organ communications in the mechanisms of growth coordination and the determination of final organ size.
- Delanoue, R., Meschi, E., Agrawal, N., Mauri, A., Tsatskis, Y., McNeill, H., and Leopold, P. (2016). Drosophila insulin release is triggered by adipose Stunted ligand to brain Methuselah receptor. Science 353, 1553-1556.
- Andersen, D.S., Colombani, J., Palmerini, V., Chakrabandhu, K., Boone, E., Rothlisberger, M., Toggweiler, J., Basler, K., Mapelli, M., Hueber, A.O. and Léopold, P. (2015). The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth. Nature 522, 482-486.
- Bjordal, M., Arquier, N., Kniazeff, J., Pin, J.P., and Leopold, P. (2014). Sensing of amino acids in a dopaminergic circuitry promotes rejection of an incomplete diet in Drosophila. Cell 156, 510-521.