Oslo University Hospital has award 6 excellent articles for the first half-year of 2014

Bjřrn Erikstein, managing director OUS

Oslo University Hospital has rewarded six research groups for their excellent papers published during the first half-year of 2014. Each group receives NOK 50.000 for use in further research. The prizes were distributed during the Friday meeting at Ullevål November 21st.
The award winners gave short presentations of the main findings in their respective articles. Managing director Bjørn Erikstein (photo) distributed the awards, and professor Ole M. Sejerstad chaired the meeting.
The six selected articles are of especially high quality, and they present important finding on both-short and long-term scales. The works reflect the good quality and the interdisciplinarity that characterises several research environments at Oslo University Hospital. The research is a fundamental condition for the institution to maintain and strenghten the quality in the patient treatment.

In order to stimulate excellent research and draw attention to the hospital's extensive research activity, Oslo University Hospital reward outstanding publications regularly. Every half-year, six of the very best papers authored by scientists working on the hospital (first or last author must be affiliated to OUS) are selected. The nomination takes place through the research panel of each division. The final selection process is performed by an external committee.

From left: Asbjørg Stray-Pedersen, Anne-Mari Håkelien, Sigrid B. Thoresen, Laxmi Silwal-Pandit, Guro Reinholt Melum, Øyvind Steinsbø. Photo: Ram Gupta (click to enlarge)

Award winners (equally ranked), excellent articles published 1st half-year 2014

Authors: Laxmi Silwal-Pandit/Anita Langerød
Institute/division: Department of Genetics, Institute for Cancer Research, Division of Cancer, Surgery and Transplantation
Journal: Clinical Cancer Research 

TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance.
Silwal-Pandit L, Vollan HK, Chin SF, Rueda OM, McKinney S, Osako T, Quigley DA, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Langerød A.
Clin Cancer Res. 2014 Jul 1;20(13):3569-80. doi: 10.1158/1078-0432.CCR-13-2943. Epub 2014 May 6.

Authors: Sigrid B. Thoresen/Harald Stenmark
Institute/division: Department for Biochemistry, Institute for Cancer Research, Division of Cancer, Surgery and Transplantation
Journal: Nature Cell Biology

ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4.
Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C, Stenmark H.
Nat Cell Biol. 2014 Jun;16(6):550-60. doi: 10.1038/ncb2959. Epub 2014 May 11.

Authors: Håkelien AM / Meza-Zepeda LA
Institute/division: Department of Tumor Biology, Institute for Cancer Research, Division of Cancer, Surgery and Transplantation
Journal: Stem Cells 

The regulatory landscape of osteogenic differentiation.
Håkelien AM, Bryne JC, Harstad KG, Lorenz S, Paulsen J, Sun J, Mikkelsen TS, Myklebost O, Meza-Zepeda LA.
Stem Cells. 2014 Oct;32(10):2780-93. doi: 10.1002/stem.1759.

Authors: Asbjørg Stray-Pedersen/ I. Celine Hanson
Institute/division: Department of Medical Genetics, Division for Diagnostics and Intervention
Journal: The American Journal of Human Genetics 

PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia.
Stray-Pedersen A, Backe PH, Sorte HS, Mørkrid L, Chokshi NY, Erichsen HC, Gambin T, Elgstøen KB, Bjørås M, Wlodarski MW, Krüger M, Jhangiani SN, Muzny DM, Patel A, Raymond KM, Sasa GS, Krance RA, Martinez CA, Abraham SM, Speckmann C, Ehl S, Hall P, Forbes LR, Merckoll E, Westvik J, Nishimura G, Rustad CF, Abrahamsen TG, Rønnestad A, Osnes LT, Egeland T, Rødningen OK, Beck CR; Baylor-Johns Hopkins Center for Mendelian Genomics, Boerwinkle EA, Gibbs RA, Lupski JR, Orange JS, Lausch E, Hanson IC.
Am J Hum Genet. 2014 Jul 3;95(1):96-107. doi: 10.1016/j.ajhg.2014.05.007. Epub 2014 Jun 12.

Authors: Øyvind Steinsbø /Ludvig M. Sollid
Institute/division: Department for Immunology and Transfusion Medisin, Division for Diagnostics and Intervention
Journal: Nature Communications

Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells.
Steinsbø Ø, Henry Dunand CJ, Huang M, Mesin L, Salgado-Ferrer M, Lundin KE, Jahnsen J, Wilson PC, Sollid LM.
Nat Commun. 2014 Jun 9;5:4041. doi: 10.1038/ncomms5041.

Authors: Guro R. Melum/ Espen S. Baekkevold
Institute/division: Department of Pathology, Division for Diagnotics and Intervention
Journal: Journal of Allergy and Clinical Immunology

A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa.
Melum GR, Farkas L, Scheel C, Van Dieren B, Gran E, Liu YJ, Johansen FE, Jahnsen FL, Baekkevold ES.
J Allergy Clin Immunol. 2014 Sep;134(3):613-621.e7. doi: 10.1016/j.jaci.2014.05.010. Epub 2014 Jun 21.

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