Llorente/Sandvig publish potential biomarkers for prostate cancer

Llorente (left) and Sandvig

Alicia Llorente and Kirsten Sandvig, Department of Biochemistry, Institute for Cancer Research and Centre for Cancer Biomedicine, have recently published in Molecular and Cellular Proteomics (impact factor 8.4) a proteomic analysis of microvesicles released from a human prostate cancer cell line. Most of the 266 proteins identified have previously been reported to be present in vesicles released from other cell types, but several proteins seem to be specific for prostate cancer cells. Since microvesicles can reach biological fluids, these proteins are thus potentially useful as new non invasive biomarkers for detection, diagnosis and/or prognosis of prostate cancer.

Links

Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3.
Sandvig K, Llorente A.
Mol Cell Proteomics. 2012 Mar 28. [Epub ahead of print]

Home page of Kirsten Sandvig's group - Intracellular transport

Sandvig's mini CV (including publications)

Department of Biochemistry

Centre for Cancer Biomedicine

Recent publications

From major journals, first or last author from the Institute for Cancer Research

Skotland T, Geir Iversen T, Llorente A, Sandvig K (2022)
Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Adv Drug Deliv Rev, 114326 (in press)
DOI 10.1016/j.addr.2022.114326, PubMed 35588953

Ianevski A, Giri AK, Aittokallio T (2022)
SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkac382, PubMed 35580060

Kidd SG, Bogaard M, Carm KT, Bakken AC, Maltau AMV, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2022)
In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis
Mol Oncol (in press)
DOI 10.1002/1878-0261.13225, PubMed 35574900

More selected publications

Most recent publications

Smirnov P, Smith I, Safikhani Z, Ba-Alawi W, Khodakarami F, Lin E, Yu Y, Martin S, Ortmann J, Aittokallio T, Hafner M, Haibe-Kains B (2022)
Evaluation of statistical approaches for association testing in noisy drug screening data
BMC Bioinformatics, 23 (1), 188
DOI 10.1186/s12859-022-04693-z, PubMed 35585485

Ianevski A, Giri AK, Aittokallio T (2022)
SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkac382, PubMed 35580060

Skotland T, Geir Iversen T, Llorente A, Sandvig K (2022)
Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Adv Drug Deliv Rev, 114326 (in press)
DOI 10.1016/j.addr.2022.114326, PubMed 35588953

More publications

Annual summary of publications