Llorente/Sandvig publish potential biomarkers for prostate cancer
Llorente (left) and Sandvig
Alicia Llorente and Kirsten Sandvig, Department of Biochemistry, Institute for Cancer Research and Centre for Cancer Biomedicine, have recently published in Molecular and Cellular Proteomics (impact factor 8.4) a proteomic analysis of microvesicles released from a human prostate cancer cell line. Most of the 266 proteins identified have previously been reported to be present in vesicles released from other cell types, but several proteins seem to be specific for prostate cancer cells. Since microvesicles can reach biological fluids, these proteins are thus potentially useful as new non invasive biomarkers for detection, diagnosis and/or prognosis of prostate cancer.
From major journals, first or last author from the Institute for Cancer Research
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Brodal HP, Pharo H, Vedeld HM, Lind GE(2025) PoDCall: a robust tool for automated droplet classification in DNA-methylation droplet digital PCR Mol Oncol(in press) DOI 10.1002/1878-0261.70105, PubMed 40761129
Radulovic M, Yang C, Stenmark H(2025) Lysosomal membrane homeostasis and its importance in physiology and disease Nat Rev Mol Cell Biol(in press) DOI 10.1038/s41580-025-00873-w, PubMed 40759742
Schmidt N, Kornrumpf K, Ries L, Markus K, Ksionsko N, Mazzeo P, Lohrberg M, Sitte M, Salinas-Riester G, Braun T, Dechow A, Herling M, Ianevski A, Aittokallio T, Chapuy B, Bastians H, Wulf GG, Beißbarth T, Dönitz J, Koch R(2025) Discovery of molecularly-informed therapeutic strategies for mature T-cell leukemias and lymphomas Blood Adv(in press) DOI 10.1182/bloodadvances.2024015167, PubMed 40758950