Ellen Margrethe Haugsten from Antoni Wiedlocha’s group at the Department of Biochemistry was awarded a prize for her talk - entitled "Clathrin – and dynamin-independent endocytosis of FGFR3 – implication for signaling", at the "Gordon Research Conference: Fibroblast Growth Factors in Development & Disease", held May 13-18, 2012 at Les Diablerets, Switzerland.
Malgorzata Zakrzewska received the price for a poster on "ERK-mediated phosphorylation of FGF receptor 1 on Ser777 confers negative feedback on FGF signaling", with Ellen M. Haugsten, Beata Nadratowska-Weselowska, Angela Oppelt, Yixin Jin, Jacek Otlewski, Jørgen Wesche and Antoni Wiedlocha,
In her talk, Ellen M. Haugsted characterized the molecular machinery involved in endocytosis of FGFR3 and further examine how internalization influences FGFR signaling.
The prizei included 200 ChF.
Data presented on the prize-winning poster by Zakrzewska et. al. reveal a novel negative-feedback mechanism that controls FGF-induced signaling and thereby protects cell against excessive activation of FGF receptor.
Gordon Research Conference: Fibroblast Growth Factors in Development & Disease, May 13-18, 2012, Les Diablerets, Switzerland.
Antoni Wiedlocha’s group
Department of Biochemistry