Anita Sveen awarded the ICR "Researcher of the Year" Prize for 2020

Anita Sveen (photo: Per M. Didriksen)
Anita Sveen (photo: Per M. Didriksen)

Anita Sveen (39) – senior researcher and project group leader at Institute for Cancer Research – was on December 16th awarded the prize Researcher-of-the-Year from the leadership at ICR for her outstanding scientific contributions. The award of 100 000 NOK is financed by the Radium Hospital Foundation (Radiumhospitalets legater) and is a personal scholarship for stimulating further excellence in research. 

Three new academic degrees defended at Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Oslo, by members of the Dept of Molecular Oncology

Tuva Høst Brunsell with main supervisor Arild Nesbakken.
Tuva Høst Brunsell with main supervisor Arild Nesbakken.

In June, Tuva Høst Brunsell (MD) digitally defended her PhD “ Heterogeneity of prognostic biomarkers in colorectal liver metastases”, Institute for Clinical Medicine, University of Oslo. The thesis includes three papers (Brunsell et al., Clin Colorectal Cancer 2020; Brunsell et al., Eur J Surg Oncol 2019; Berg*, Brunsell* et al., submitted).

On September the 4th, Christer Anker Andreassen, digitally defended his MSc, Institute of Biosciences, University of Oslo. “The functional and clinical impact of the E3 Ubiquitin ligase NEDD4 in colorectal cancer and its role in regulating PTEN and P53”.

On September the 11th, Mikael Ravndal, defended his MSc, Department of Informatics, University of Oslo. "Algorithms for exploring heterogeneity in prostate cancer patients from RNA-seq data".

TP53 proficient colorectal cancer cells are sensitive to PARP inhibition

Jørgen Smeby (left) and Kushtrim Kryeziu are shared first authors
Jørgen Smeby (left) and Kushtrim Kryeziu are shared first authors

By examining vulnerabilities in colorectal cancer, Jørgen Smeby, Kushtrim Kryeziu, and colleagues demonstrated the efficacy of PARP inhibitors for a subgroup of colorectal cancer cell lines in a recent paper in EBioMedicine (The Lancet’s open access).

The cancer patient’s own drug sensitivity model

From left: Eide, Kryeziu and Bruun.

The cancer patient’s own drug sensitivity model: researchers from the Lothe lab and collaborators recently published a paper in Clinical Cancer Research describing ex vivo patient-derived organoids from colorectal liver metastases in a heterogeneity context. 

Drs. Jarle Bruun, Kushtrim Kryeziu and Peter W. Eide (photo) were shared 1st authors , and have established the PDO lineages and drug screen analyses.

Jørgen Smeby the first to defend his PhD digitally at the Institute for Cancer Research

Jørgen Smeby during the digital PhD defence

The first digital PhD defence at the Institute for Cancer Research was held on the 20th of April 2020.

Dr. Jørgen Smeby defended his thesis "Molecular subtype-dependent impact of driver mutations in colorectal cancer" submitted to the Faculty of Medicine, University of Oslo.

The work was performed in the Lothe lab at the Institute for Cancer Research. 

Scientific achievements at Dept Molecular Oncology in 2019

As we enter a new year, we can look back on our scientific achievements in 2019. Dept Mol Oncol is one of six research departments at the Institute for Cancer Research, and we account for about 10% of the total staff (full-time equivalent). Harvesting from a positive working environment and active collaborations among our three research groups, we can document an upward trajectory in the volume, citation numbers, and impact of our research publications.

Kaja Christine Graue Berg defended her PhD on the 10th Dec 2019

She has performed her work in the Lothe lab., and has been a PhD student at the Institute for Clinical Medicine, Faculty of Medicine, U of Oslo.

The thesis  “Integrated genomics of colorectal cancer” included three papers of which she is the 1st author (Molecular Cancer 2017, Oncogene 2019, submitted manuscript).

The candidate held an excellent trial lecture “The gut microbiome as an emerging target for cancer therapy”, and she had a good discussion with her two opponents professors Karin Jirstrøm and Eirik Frengen (photo, candidate to the right).

Young researcher award to Peter Wold Eide at “Onkologisk Forum”

Dr. Peter Wold Eide, post doc in the Lothe lab received the "Young researcher award" for his scientific accomplishments during the 2019 Onkologisk forum held in Tromsø November 21st-22nd .

The evaluation committee pointed out his competence in cell biology, bioinformatics and pharmacogenomics, and that his research assessing drug sensitivities in combination with genomics in patient derived preclinical models is important for further development of precision oncology. 

The 2019 Oslo University Hospital Researcher Awards to Andreassen, Kalager and Sveen

Ole Andreassen, Merete Kalager and Anita Sveen (photo: Dag Kristiansen).

Three scientists received awards for their outstanding research at a ceremony taking place at Oslo University Hospital August 23rd. 

The major prize - the "Excellent Researcher Award" - went to Ole A. Andreassen. Mette Kalager and Anita Sveen both received the "Early Career Award".

Aug 2019Jun 2019Oct 2018Jun 2018Mar 2018Jan 2018Nov 2017Aug 2017Jun 2017Apr 2017Aug 2016Jun 2016Mar 2016Feb 2016Dec 2015Nov 2015Sep 2015Aug 2015Jun 2015May 2015Feb 2015Dec 2014Nov 2014Sep 2014Jul 2014May 2014Apr 2014Dec 2013Nov 2013Sep 2013May 2013Apr 2013Oct 2012Aug 2012Mar 2012Feb 2012Jan 2012Nov 2011Jun 2011May 2011Apr 2011Dec 2010Nov 2010Jun 2010May 2010Mar 2010Feb 2010Nov 2009Jun 2009May 2009Jan 2009Dec 2008Nov 2008Oct 2008Sep 2008Aug 2008Jun 2008May 2008Apr 2008Feb 2008Jan 2008Dec 2007Nov 2007