Members of the Lothe group and researchers in the KG Jebsen Centre for Colorectal Cancer Research have recently published a comprehensive review in BBA Reviews on Cancer on the mechanisms leading to excessive PI3K/AKT signaling in colorectal cancer. In this atrticle, they also revisited the PI3K/AKT-pathway cancer susceptibility syndromes and summarized the prognostic and predictive values of the alterations at the different regulatory levels of the PI3K pathway in colorectal cancer.
BladMetrix: a novel urine DNA methylation test with high accuracy for detection of bladder cancer in hematuria patients
Clin Epigenetics, 14 (1), 115
Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
Int J Cancer (in press)