NoPSC study of PSC gut microbiota published in Gut

First author Martin Kummen (left) and senior author Johannes Hov
First author Martin Kummen (left) and senior author Johannes Hov
The gut microbiota of patients with primary sclerosing cholangitis (PSC) has low diversity and is highly different from both healthy individuals and inflammatory bowel disease patients without PSC, according to a study by Martin Kummen and co-workers, which is now published online in the prestigious journal Gut (journal impact factor 14.66).

The study represents a milestone at Norwegian PSC Research Center, being the first entirely based on in-house methodology, and also providing an important starting point for studies on the clinical application of gut microbiota in this disease.


Original article
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Martin Kummen, Kristian Holm, Jarl Andreas Anmarkrud, Ståle Nygård, Mette Vesterhus, Marte L Høivik, Marius Trøseid, Hanns-Ulrich Marschall, Erik Schrumpf, Bjørn Moum, Helge Røsjø, Pål Aukrust, Tom H Karlsen, Johannes R Hov
Published Online First 17 February 2016

Home page of Norwegian PCS (primary sclerosing cholangitis) Research Center - NoPSC

Blog article about the project written by Martin Kummen, from the OUS research blog (in Norwegian):
Tett forhold mellom tarm og lever (translated to: "Close relationship between gut and liver")

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