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22.05.2019Incidence rates of aggressive subtypes of uterine cancer rising, study shows
New findings show that U.S. incidence rates for aggressive subtypes of uterine cancer rose rapidly among women ages 30 to 79 from 2000 to 2015.
22.05.2019Bipolar disorder may be linked to Parkinson's disease
People who have bipolar disorder may be more likely to later develop Parkinson's disease than people who do not have bipolar disorder, according at a new study.
22.05.2019Hypertension found in children exposed to flower pesticides
Researchers have found higher blood pressure and pesticide exposures in children associated with a heightened pesticide spraying period around the Mother's Day flower harvest. This study involved boys and girls living near flower crops in Ecuador.
22.05.2019Big energy savings for tiny machines
Physicists demonstrate for the first time a strategy for manipulating the trillions of tiny molecular nanomachines inside us that work to keep us alive, to maximize efficiency and conserve energy. The breakthrough could impact numerous fields, including creating more efficient computer chips and solar cells for energy generation.
22.05.2019Surgery patients: Getting older every year
A new analysis reveals that people undergoing surgery in England are getting older at a faster rate than the general population.
22.05.2019Scientists discover novel genes responsible for regulating muscle cells
Scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.
22.05.2019Infants later diagnosed with autism seldom initiate joint attention
A new study shows that infants who are later diagnosed with autism react adequately when others initiate joint attention, but seldom actively seek to establish such episodes themselves. This finding provides support for the view that children with autism have reduced social motivation already as infants.
22.05.2019Eating healthily at work matters
A new study has demonstrated that employees at a large urban hospital who purchased the least healthy food in its cafeteria were more likely to have an unhealthy diet outside of work, be overweight and/or obese, and have risk factors for diabetes and cardiovascular disease, compared to employees who made healthier purchases.
22.05.2019Study identifies dog breeds, physical traits that pose highest risk of biting children
Nearly five million people are bitten by dogs each year in the United States, and children are at a much higher risk than adults. Dog bites can cause significant psychological and physical damage, and bites to the face often require reconstructive surgery to repair injuries ranging from nerve damage to tissue loss. While certain breeds are known to bite more frequently or cause more severe injuries, a new study finds the breed was unknown in about 60 percent of dog bite cases.
22.05.2019Positive aspects of masculinity helps improve boys' attitudes toward relationship violence
A program aimed at reducing violence against women and girls by focusing on positive expressions of masculinity changed the attitudes of middle school boys who may have been prone to harassment and dating violence as they got older, according to a study that was done in partnership with prevention practitioners in New England.
22.05.2019New study estimates preventable cancer burden linked to poor diet in the US
A new study has estimated the association between suboptimal consumption of seven types of foods and specific cancers. They found that poor diet is on par with alcohol, excessive body weight, and physical activity.
22.05.2019New role in spatial chromosome organization identified for often mutated cancer protein
New research sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers.
22.05.2019A road map to stem cell development
Researchers have developed a way to map retinal cell development and potentially advance regenerative medicine.
22.05.2019Massive sequencing study links rare DNA alterations to type 2 diabetes
An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes. From this large cohort the researchers identified four genes with rare variants that affect diabetes risk. The data suggests that hundreds more genes will likely be identified in the future.
22.05.2019Experimental noninvasive tool monitors effectiveness of stem cell transplantation
Other than clinical observations, the stem cell field lacks a repeatable, time-sensitive, noninvasive tool to assess the effectiveness of transplanted cells in the targeted organ. Researchers analyzed biomarkers secreted from transplanted human stem cells in the recipient blood of a rodent model of heart attack. Analysis of the blood test showed responding cells had changed their gene expression, behavior and secretions, suggesting this liquid biopsy could provide a window into stem cell activity and effectiveness.
22.05.2019Promising path towards developing flu treatment using lipid target
A team of scientists has tackled this fundamental question and recently identified a target to 'tone down' the hyper-active immunity to influenza infection. These novel findings have promising clinical implications in the near future for the treatment of flu.
22.05.2019Electric hookahs might be no safer than traditional charcoal-based ones
Waterpipe tobacco smoking, otherwise known as 'hookah' or 'shisha,' is becoming increasingly popular worldwide, especially among youth. Traditional hookahs burn charcoal as a heat source, but recently, electrical heating elements (EHEs) have been introduced to the market. Reinforced by product advertising and package labeling, many hookah smokers believe that EHEs are less harmful than charcoal. Now, researchers report that although EHEs reduce some toxicants, they increase others.
22.05.20193D-printed device detects biomarkers of preterm birth
Preterm birth (PTB) -- defined as birth before the 37th week of gestation -- is the leading complication of pregnancy. If doctors had a simple, accurate and inexpensive way to identify women at risk for the condition, they could develop better prevention strategies. Now researchers have created a 3D-printed microchip electrophoresis device that can sensitively detect three serum biomarkers of PTB.
22.05.2019Octopus-inspired wearable sensor
Wearable electronics that adhere to skin are an emerging trend in health sensor technology for their ability to monitor a variety of human activities, from heart rate to step count. But finding the best way to stick a device to the body has been a challenge. Now, a team of researchers reports the development of a graphene-based adhesive biosensor inspired by octopus 'suckers.'
22.05.2019Healthy brain development is a human right, argues Yale researcher
We know that the environment in which children and young adults are raised influences healthy brain development. Now, a psychologist is taking a stance against the negative effects of a particularly harrowing environment in her own backyard: the US prison system. The author declares that everybody, including young offenders, deserves healthy brain development -- a right she says US jails often infringe upon.
22.05.2019Residential child care project addresses emotional pain without causing it
A model of care for children's residential agencies takes children's emotional pain into account and emphasizes the bond between the children and their caregivers.
22.05.2019Pain management protocol sends 92 percent of cancer surgery patients home without opioids
A specialized pain management program for patients who underwent robotic surgery for urologic cancers resulted in just eight percent going home with narcotics after discharge, compared to 100 percent who would have received them without this enhanced recovery protocol.
22.05.2019Cell division requires a balanced level of non-coding RNA for chromosome stability
Scientists have discovered that centromeric DNA is used as a template to produce a non-protein coding, centromeric RNA (ribonucleic acid), that is essential for chromosome stability. If there is too much or too little centromeric RNA (cenRNA), the centromere will be defective and chromosomes will be lost.
22.05.2019AI to enhance cognitive performance?
Results of a pilot study have provided evidence that an artificial intelligence known as CURATE.AI has the potential to enhance learning, and could pave the way for promising applications in personalized digital therapy, including the prevention of cognitive decline.
22.05.2019Monkey-infecting virus may provide part of future HIV vaccine
A protein from Simian Immunodeficiency Virus (SIV), which can infect monkeys and apes, has shown promise as a potential component of a vaccine against Human Immunodeficiency Virus (HIV).
22.05.2019Why some parasitic worms persist in people
A new study may explain why some people struggle to expel parasitic worms that infect their intestines. The research suggests that the phenomenon is primarily a numbers game: Large groups of worms can overwhelm the immune system and kick-start a self-perpetuating cycle that nearly guarantees their survival, whereas smaller groups and lone worms cannot.
22.05.2019Exposing vaccine hesitant to real-life pain of diseases makes them more pro-vaccine
New research finds there is a better way to help increase support for vaccinations: Expose people to the pain and suffering caused by vaccine-preventable diseases instead of trying to combat people with vaccine facts.
22.05.2019Newly discovered hybrid molecules could serve as a novel category of anti-cancer agent
Researchers have developed and studied the biological activity of five new, metal-organic hybrid knotted molecules, termed metal-organic trefoil knots (M-TKs). These molecules can effectively deliver metals to cancer cells, demonstrating the potential to act as a new category of anti-cancer agents.
22.05.2019Poor semen quality in Switzerland
A marked decrease in sperm count has been observed. And in Switzerland? Researchers have undertaken the first nationwide assessment of the semen quality. The scientists assessed the number of spermatozoa, their motility and morphology. The results were well below the reference values issued by the WHO. The current situation is a matter of concern since the poor semen quality of Swiss men is associated with an increase in the incidence of testicular cancer.
22.05.2019Exercise may help teens sleep longer, more efficiently
Getting more exercise than normal -- or being more sedentary than usual -- for one day is enough to affect sleep later that night. Researchers found that when teenagers got more physical activity than they usually did, they got to sleep earlier, slept longer and slept better that night.
22.05.2019Aspirin green light for brain bleed stroke patients, study suggests
People who suffer a stroke caused by bleeding in the brain -- known as brain haemorrhage -- can take common medicines without raising their risk of another stroke, a major clinical trial has found. Researchers say the findings are reassuring for the thousands of people who take the medicines to reduce their risk of heart attack and another common type of stroke caused by blood clots in the brain.
22.05.2019Civil War plant medicines blast drug-resistant bacteria in lab tests
A new study based on a mostly forgotten guide to medicinal plants, 'Resources of the Southern Fields and Forests,' focuses on three of the plants and shows they inhibit bacteria associated with wound infections.
22.05.2019Early life exposure to nicotine alters neurons, predisposes brain to addiction later
In a new mouse study, neonatal exposure to nicotine changed the biochemistry of reward circuitry in the brain. Researchers suggest the same mechanism may be at work in humans.
22.05.2019Space travel and your joints
A novel study of mice aboard a Russian spaceflight may raise an intriguing question for the astronauts of tomorrow: Could traveling in space be bad for your joints? Researchers found early signs of cartilage breakdown in the mice, suggesting that the reduced biomechanical forces of spaceflight are at play on the musculoskeletal system.
22.05.2019River valleys helped shape current genetic landscape of Han Chinese
New research shows the importance of how the three main river valleys in China contributed to Han genetic diversity.
22.05.2019Contact with nature during childhood could lead to better mental health in adulthood
Almost 3,600 people participated in a European study on the impact of green and blue spaces on mental health and vitality.
22.05.2019Women are less likely to be resuscitated and survive a cardiac arrest than men
Women who have a cardiac arrest outside the hospital setting are less likely to receive resuscitation from bystanders and more likely to die than men, according to new research. Researchers looked at data from nearly 6,000 people who had resuscitation attempts between 2006 and 2012 and found that women were less likely to receive resuscitation attempts from bystanders and less likely to survive a cardiac arrest than men.
22.05.2019New method could shed light on workers' historical radiation exposure
Researchers in the UK have developed a new method for evaluating plutonium workers' historical internal radiation exposure. They focused their efforts on workers employed at the start of plutonium operations at the Sellafield (formerly Windscale) nuclear reprocessing facility in the UK.
21.05.2019Potential breakthrough in understanding tumor dormancy
Scientists may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to investigate the potential for novel therapeutics that target and destroy cells in a specific state of tumor dormancy.
21.05.2019Geneticists continue to unravel how genes impact drug use and addiction
Research is revealing new insights into how genes impact drug use and addiction through a novel study of susceptibility to the effects of cocaine and methamphetamine in fruit flies.
21.05.2019Doctors can estimate patient adherence by simply asking about medication routine
Doctors know patients do not always take their medications as prescribed. To help them stay on track, new research suggests doctors stop asking patients about missed pills and start asking about their routines.
21.05.2019Children with cancer wait an average of 6.5 years longer than adults to access new drugs
An analysis of 117 cancer drugs approved by the US FDA over a 20-year period finds the drugs took a median of 6.5 years to go from the first clinical trial in adults to the first trial in children.
21.05.2019Air pollution linked to childhood anxiety
A new study looks at the correlation between exposure to traffic-related air pollution (TRAP) and childhood anxiety, by looking at the altered neurochemistry in pre-adolescents.
21.05.2019Multiple brain regions moderate and link depressive mood and pain
New research expands and deepens the association between clinical depression and pain, identifying specific regions of the brain that drive, influence and moderate depressive mood and its relationship to perceiving physical pain.
21.05.2019Summit charts a course to uncover the origins of genetic diseases
A team used the 200-petaflop IBM AC922 Summit system, the world's smartest and most powerful supercomputer, to develop an integrative model of the transcription preinitiation complex (PIC), a complex of proteins vital to gene expression.
21.05.2019Only half of US kids and teens have ideal cholesterol levels
Cholesterol levels in US youth have improved from 1999 to 2016, but only half of children and adolescents are in the ideal range and 25% are in the clinically high range, according to a new study.
21.05.2019Dawn-to-sunset fasting suggests potential new treatment for obesity-related conditions
Fasting from dawn to sunset for 30 days increased levels of proteins that play a crucial role in improving insulin resistance and protecting against the risks from a high-fat, high-sugar diet, according to researchers.
21.05.2019Statistical model could predict future disease outbreaks
Researchers have created a statistical method that may allow public health and infectious disease forecasters to better predict disease reemergence, especially for preventable childhood infections such as measles and pertussis.
21.05.2019Insulin under the influence of light
By understanding how the brain links the effects of insulin to light, researchers are deciphering how insulin sensitivity fluctuates according to circadian cycles. At the heart of their discovery are neurons of the ventromedial hypothalamic nucleus, a part of the brain that masters this balance. These results should also encourage diabetic patients to consider the best time to take insulin to properly control its effect and limit the risk of hypoglycemia.
21.05.2019Exercise: Psych patients' new primary prescription
A new study advocates for exercise as the primary method of treatment and intervention, rather than psychotropic medications, within inpatient psychiatric facilities.
21.05.2019Stem cell differences could explain why women are more likely to develop adrenal cancer
Scientists have discovered a potential biological reason why women are more likely to develop adrenal disorders, including cancer. According to the researchers, the answer could lie in the increased turnover of hormone-producing cells found in the adrenal glands of females.
21.05.2019Successful HIV effort prompts call for clinics to expand mental health services on site
Increasing access to mental health services improves HIV outcomes among vulnerable patients, a new study suggests. Based on their findings, the researchers are urging HIV clinics to expand their mental health services on site.
21.05.2019Blood proteins help predict risk of developing heart failure
Two blood proteins help predict more accurately the risk for heart attack, stroke and heart failure hospitalization.
21.05.2019New opioid speeds up recovery without increasing pain sensitivity or risk of chronic pain
A new type of non-addictive opioid accelerates recovery time from pain compared to morphine without increasing pain sensitivity, according to a new study.
21.05.2019Young athletes who require ACL reconstruction may benefit from additional procedure
An anterior cruciate ligament (ACL) tear, an injury of the knee, can be devastating to a young athlete. While the ACL can be reconstructed through surgery, there is a high risk of re-injury in patients under the age of 25. In the largest clinical trial of its kind, researchers have shown that performing an additional surgical procedure called lateral extra-articular tenodesis (LET) may reduce the risk of ACL re-injury in young athletes.
21.05.2019The cultural significance of carbon-storing peatlands to rural communities
A group of researchers have carried out the first detailed study of how rural communities interact with peatlands in the Peruvian Amazon, a landscape that is one of the world's largest stores of carbon.
21.05.2019First in human results show early bird device effective in early detection of internal bleeding
New study results validate the effectiveness of the Saranas Early Bird Bleed Monitoring System to sense bleeding events during endovascular related procedures by using sensors to detect relative changes in tissue bioimpedance. The study enrolled 60 patients from five sites who underwent an endovascular procedure and detected bleeding in more than half of patients.
21.05.2019How molecular escorts help prevent cancer
The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide. New research shows that this inborn cancer prevention only works when special proteins, known as chaperones, allow it to take place.
21.05.2019After GWAS studies, how to narrow the search for genes?
Genome-wide association studies (GWAS) often turn up a long list of genes that MIGHT help cause the trait of interest. Many algorithms can help scientists prioritize which genes to pursue further, but which one to choose? Borrowing from machine learning, and singling out one chromosome at a time, a new tool called Benchmarker helps scientists evaluate existing algorithms to guide their search for relevant genes.
21.05.2019Cancer: Using 3D to test personalized treatments in five days
Researchers have devised a cell co-culture platform that reproduces a patient's tumor structure in 3D. The scientists can use it to test several drugs or their combinations at different stages of the tumor's development. They now need only five days to identify which treatment will be most effective for a particular case, and the combination can then be translated for clinical practice.