Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Division of Paediatric and Adolescent Medicine

67 publications found

Aden P, Gjerstad AC, Skari H, Lie A, Bjerre A (2020)
Nevrogene blæreforstyrrelser hos barn
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.18.0347, PubMed 32105040

Aden P, Gjerstad AC, Skari H, Lie A, Bjerre A (2020)
Neurological bladder disorders in children
Tidsskr. Nor. Laegeforen., 140 (3), 260-265

Albatat M, Bergsland J, Arevalo H, Odland HH, Wall S, Sundnes J, Balasingham I (2020)
Multisite pacing and myocardial scars: a computational study
Comput Methods Biomech Biomed Engin
DOI 10.1080/10255842.2020.1711885, PubMed 31958019

Andelic N, Forslund MV, Perrin PB, Sigurdardottir S, Lu J, Howe EI, Sveen U, Rasmussen MS, Søberg HL, Røe C (2020)
Long-term follow-up of use of therapy services for patients with moderate-to-severe traumatic brain injury
J Rehabil Med, 52 (3), jrm00034
DOI 10.2340/16501977-2662, PubMed 32179933

Andersen ØS, Krogh MR, Boe E, Storsten P, Aalen JM, Larsen CK, Skulstad H, Odland HH, Smiseth OA, Remme EW (2020)
Left Bundle Branch Block Increases Left Ventricular Diastolic Pressure during Tachycardia due to Incomplete Relaxation
J Appl Physiol (1985) (in press)
DOI 10.1152/japplphysiol.01002.2018, PubMed 31999529

Andresen JH, Saugstad OD (2020)
50 Years Ago in TheJournal ofPediatrics: Positive Pressure Ventilation in the Newborn Infant: The Use of a Face Mask
J Pediatr, 217, 97
DOI 10.1016/j.jpeds.2019.08.054, PubMed 32040416

Andresen JH, Saugstad OD (2020)
50 Years Ago in TheJournalofPediatrics: When the Lung Ruptures - 50 Years Ago and Today
J Pediatr, 219, 75
DOI 10.1016/j.jpeds.2019.10.004, PubMed 32204808

Andresen JH, Saugstad OD (2020)
50 Years Ago in TheJournalofPediatrics: Chromosome Studies in Full Term, Low Birth Weight, Mentally Retarded Patients
J Pediatr, 218, 56
DOI 10.1016/j.jpeds.2019.09.032, PubMed 32089188

Andresen JH, Saugstad OD (2020)
50 Years Ago in TheJournal ofPediatrics: Human Chromosomal Deletion: Two Patients with the 4p-Syndrome
J Pediatr, 216, 72
DOI 10.1016/j.jpeds.2019.07.020, PubMed 31843122

Andresen JH, Saugstad OD (2020)
Oxygen metabolism and oxygenation of the newborn
Semin Fetal Neonatal Med, 101078 (in press)
DOI 10.1016/j.siny.2020.101078, PubMed 32037265

Arfa S, Solvang PK, Berg B, Jahnsen R (2020)
Disabled and immigrant, a double minority challenge: a qualitative study about the experiences of immigrant parents of children with disabilities navigating health and rehabilitation services in Norway
BMC Health Serv Res, 20 (1), 134
DOI 10.1186/s12913-020-5004-2, PubMed 32087730

Birketvedt K, Mikkelsen A, Klingen LL, Henriksen C, Helland IB, Emblem R (2020)
Nutritional Status in Adolescents with Esophageal Atresia
J Pediatr, 218, 130-137
DOI 10.1016/j.jpeds.2019.11.034, PubMed 31982089

Bonthuis M, Groothoff JW, Ariceta G, Baiko S, Battelino N, Bjerre A, Cransberg K, Kolvek G, Maxwell H, Miteva P, Molchanova MS, Neuhaus TJ, Pape L, Reusz G, Rousset-Rouviere C, Sandes AR, Topaloglu R, Van Dyck M, Ylinen E, Zagozdzon I, Jager KJ, Harambat J (2020)
Growth Patterns After Kidney Transplantation in European Children Over the Past 25 Years: An ESPN/ERA-EDTA Registry Study
Transplantation, 104 (1), 137-144
DOI 10.1097/TP.0000000000002726, PubMed 30946218

Bratseth V, Margeirsdottir HD, Heier M, Solheim S, Arnesen H, Dahl-Jørgensen K, Seljeflot I (2020)
Procoagulant activity in children and adolescents on intensive insulin therapy
Pediatr Diabetes (in press)
DOI 10.1111/pedi.12978, PubMed 31943582

Bronsky J, Campoy C, Embleton N, Fewtrell M, Mis NF, Gerasimidis K, Hojsak I, Hulst J, Indrio F, Lapillonne A, Molgaard C, Moltu SJ, Verduci E, Vora R, Domellöf M, ESPGHAN Committee on Nutrition (2020)
Response to Letter to the Editor: Palm Oil and Beta-Palmitate in Infant Formula
J Pediatr Gastroenterol Nutr, 70 (3), e64
DOI 10.1097/MPG.0000000000002594, PubMed 31860539

Brusletto BS, Løberg EM, Hellerud BC, Goverud IL, Berg JP, Olstad OK, Gopinathan U, Brandtzaeg P, Øvstebø R (2020)
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis
Front Cell Infect Microbiol, 10, 42
DOI 10.3389/fcimb.2020.00042, PubMed 32154187

Bøhmer T, Bachtyari Z, Sommer C, Hammerstad SS (2020)
Auto regulatory capacity of the thyroid gland after numerous iodinated contrast media investigations
Scand J Clin Lab Invest
DOI 10.1080/00365513.2019.1709658, PubMed 31990217

Devulapalli CS (2020)
Non-coeliac gluten sensitivity in children
Tidsskr Nor Laegeforen, 140 (2)
DOI 10.4045/tidsskr.19.0777, PubMed 32026861

Fosdahl MA, Jahnsen R, Pripp AH, Holm I (2020)
Change in popliteal angle and hamstrings spasticity during childhood in ambulant children with spastic bilateral cerebral palsy. A register-based cohort study
BMC Pediatr, 20 (1), 11
DOI 10.1186/s12887-019-1891-y, PubMed 31914961

Gerasimidis K, Bronsky J, Catchpole A, Embleton N, Fewtrell M, Hojsak I, Indrio F, Hulst J, Köglmeier J, de Koning B, Lapillonne A, Molgaard C, Moltu SJ, Norsa L, Verduci E, Domellöf M, ESPGHAN Committee on Nutrition (2020)
Assessment and Interpretation of Vitamin and Trace Element Status in Sick Children. A Position Paper from the ESPGHAN Committee in Nutrition
J Pediatr Gastroenterol Nutr (in press)
DOI 10.1097/MPG.0000000000002688, PubMed 32142007

Grinde D, Øverland T, Lima K, Schjalm C, Mollnes TE, Abrahamsen TG (2020)
Complement Activation in 22q11.2 Deletion Syndrome
J Clin Immunol (in press)
DOI 10.1007/s10875-020-00766-x, PubMed 32152940

Gul KA, Strand J, Pettersen RD, Brun H, Abrahamsen TG (2020)
T-cell Receptor Excision Circles in Newborns with Heart Defects
Pediatr Cardiol (in press)
DOI 10.1007/s00246-020-02317-y, PubMed 32166410

Gustavsen A, Njerve IU, Sitras V, Haugen G, Tollofsrud PA, Akkok CA (2020)
A young woman with a transfusion-related pregnancy complication
Tidsskr. Nor. Laegeforen., 140 (1), 58-61

Gustavsen A, Njerve IU, Sitras V, Haugen G, Tølløfsrud PA, Akkök ÇA (2020)
A young woman with a transfusion-related pregnancy complication
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0117, PubMed 31948214

Haflidadottir S, Matthews IL, Almaas R (2020)
Cytokine profile in children with food allergy following liver transplantation
Pediatr Transplant, 24 (2), e13657
DOI 10.1111/petr.13657, PubMed 32067305

Hammerstad SS, Blackard JT, Lombardi A, Owen RP, Concepcion E, Yi Z, Zhang W, Tomer Y (2020)
Hepatitis C Virus Infection of Human Thyrocytes: Metabolic, Hormonal, and Immunological Implications
J Clin Endocrinol Metab, 105 (4)
DOI 10.1210/clinem/dgz241, PubMed 31784757

Hodnekvam K, Iversen HH, Brunborg C, Skrivarhaug T (2020)
Development and validation of a questionnaire to assess young patients' experiences with diabetes care and transition
Acta Paediatr
DOI 10.1111/apa.15205, PubMed 31998990

Hunderi JOG, Rolfsjord LB, Carlsen KCL, Holst R, Bakkeheim E, Berents TL, Carlsen KH, Skjerven HO (2020)
Virus, allergic sensitisation and cortisol in infant bronchiolitis and risk of early asthma
ERJ Open Res, 6 (1)
DOI 10.1183/23120541.00268-2019, PubMed 32201686

Juul-Dam KL, Ommen HB, Nyvold CG, Walter C, Vålerhaugen H, Kairisto V, Abrahamsson J, Alm SJ, Jahnukainen K, Lausen B, Reinhardt D, Zeller B, von Neuhoff N, Fogelstrand L, Hasle H (2020)
Measurable residual disease assessment by qPCR in peripheral blood is an informative tool for disease surveillance in childhood acute myeloid leukaemia
Br J Haematol (in press)
DOI 10.1111/bjh.16560, PubMed 32175599

Juvodden HT, Viken MK, Nordstrand SEH, Viste R, Westlye LT, Thorsby PM, Lie BA, Knudsen-Heier S (2020)
HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives
Sleep, 43 (3)
DOI 10.1093/sleep/zsz239, PubMed 31606740

Kildahl AN, Berg LK, Nilssen ALE, Bjorgo K, Rodningen O, Helverschou SB (2020)
Psychiatric assessment in Phelan-McDermid Syndrome (22q13 deletion syndrome)
J. Intellect. Dev. Dis., 45 (1), 54-58

Kjoelaas S, Tillerås KH, Feragen KB (2020)
The Ripple Effect: A Qualitative Overview of Challenges When Growing Up in Families Affected by Huntington's Disease
J Huntingtons Dis (in press)
DOI 10.3233/JHD-190377, PubMed 32065801

Kynoe NM, Fugelseth D, Hanssen I (2020)
When a common language is missing: Nurse-mother communication in the NICU. A qualitative study
J Clin Nurs
DOI 10.1111/jocn.15212, PubMed 32045074

Ladenstein R, Pötschger U, Valteau-Couanet D, Luksch R, Castel V, Ash S, Laureys G, Brock P, Michon JM, Owens C, Trahair T, Chi Fung Chan G, Ruud E, Schroeder H, Beck-Popovic M, Schreier G, Loibner H, Ambros P, Holmes K, Castellani MR, Gaze MN, Garaventa A, Pearson ADJ, Lode HN (2020)
Investigation of the Role of Dinutuximab Beta-Based Immunotherapy in the SIOPEN High-Risk Neuroblastoma 1 Trial (HR-NBL1)
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020309, PubMed 32013055

Lande A, Fluge Ø, Strand EB, Flåm ST, Sosa DD, Mella O, Egeland T, Saugstad OD, Lie BA, Viken MK (2020)
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Sci Rep, 10 (1), 5267
DOI 10.1038/s41598-020-62157-x, PubMed 32210306

Lie A, Fossum V, Aden P, Teigen C, Bjerre A, Gjerstad AC, Skari H (2020)
Lower urinary tract dysfunction in children a practical approach
Tidsskr. Nor. Laegeforen., 140 (2), 155-159

Lie A, Gjerstad AC, Fossum V, Teigen C, Skari H, Aden P, Bjerre A (2020)
Lower urinary tract dysfunction in children - a practical approach
Tidsskr Nor Laegeforen, 140 (2)
DOI 10.4045/tidsskr.18.0565, PubMed 32026859

Lund Håheim L, Schwarze PE, Thelle DS, Nafstad P, Rønningen KS, Olsen I (2020)
Low levels of antibodies for the oral bacterium Tannerella forsythia predict cardiovascular disease mortality in men with myocardial infarction: A prospective cohort study
Med Hypotheses, 138, 109575 (in press)
DOI 10.1016/j.mehy.2020.109575, PubMed 32088522

Lund-Blix NA, Tapia G, Mårild K, Brantsaeter AL, Njølstad PR, Joner G, Skrivarhaug T, Størdal K, Stene LC (2020)
Maternal and child gluten intake and association with type 1 diabetes: The Norwegian Mother and Child Cohort Study
PLoS Med, 17 (3), e1003032
DOI 10.1371/journal.pmed.1003032, PubMed 32119659

Melby KK, Carlsen KL, Håland G, Samdal HH, Carlsen KH (2020)
Helicobacter pylori in early childhood and asthma in adolescence
BMC Res Notes, 13 (1), 79
DOI 10.1186/s13104-020-04941-6, PubMed 32070394

Merid SK, Novoloaca A, Sharp GC, Küpers LK, Kho AT, Roy R, Gao L, Annesi-Maesano I, Jain P, Plusquin M, Kogevinas M, Allard C, Vehmeijer FO, Kazmi N, Salas LA, Rezwan FI, Zhang H, Sebert S, Czamara D, Rifas-Shiman SL, Melton PE, Lawlor DA, Pershagen G, Breton CV, Huen K et al. (2020)
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
Genome Med, 12 (1), 25
DOI 10.1186/s13073-020-0716-9, PubMed 32114984

Murzakanova G, Räisänen S, Jacobsen AF, Sole KB, Bjarkø L, Laine K (2020)
Adverse perinatal outcomes in 665,244 term and post-term deliveries-a Norwegian population-based study
Eur J Obstet Gynecol Reprod Biol, 247, 212-218
DOI 10.1016/j.ejogrb.2020.02.028, PubMed 32146227

Nag HE, Nærland T (2020)
Age-related changes in behavioural and emotional problems in Smith-Magenis syndrome measured with the Developmental Behavior Checklist
J Intellect Disabil, UNSP 1744629519901056
DOI 10.1177/1744629519901056, PubMed 31984836

Nava T, Ansari M, Dalle JH, de Heredia CD, Güngör T, Trigoso E, Falkenberg U, Bertaina A, Gibson B, Jarisch A, Balduzzi A, Boenig H, Krivan G, Vettenranta K, Matic T, Buechner J, Kalwak K, Lawitschka A, Yesilipek A, Lucchini G, Peters C, Turkiewicz D, Niinimäki R, Diesch T, Lehrnbecher T et al. (2020)
Supportive care during pediatric hematopoietic stem cell transplantation: beyond infectious diseases. A report from workshops on supportive care of the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)
Bone Marrow Transplant
DOI 10.1038/s41409-020-0818-4, PubMed 32029909

Oerbeck B, Overgaard KR, Hjellvik V, Bramness JG, Hansen BH, Lien L (2020)
The Use of Sleep Medication in Youth Residential Care
J Child Adolesc Psychopharmacol
DOI 10.1089/cap.2019.0172, PubMed 31976753

Ona HN, Larsen K, Nordheim LV, Brurberg KG (2020)
Effects of Pivotal Response Treatment (PRT) for Children with Autism Spectrum Disorders (ASD): a Systematic Review
Rev. J. Autism Dev. Disord., 7 (1), 78-90

Pienar C, Benninga MA, Broekaert IJ, Dolinsek J, Mas E, Miele E, Orel R, Ribes-Koninckx C, Thomassen RA, Thomson M, Tzivinikos C, Thapar N (2020)
Drugs in Focus: The Use of Racecadotril in Paediatric Gastrointestinal Disease
J Pediatr Gastroenterol Nutr, 70 (2), 162-164
DOI 10.1097/MPG.0000000000002574, PubMed 31978009

Saugstad OD (2020)
What did I learn as a neonatologist over 40 years and what impact did Napoleon have on modern newborn medicine?
Acta Paediatr
DOI 10.1111/apa.15170, PubMed 31943367

Schrier L, Hadjipanayis A, Stiris T, Ross-Russell RI, Valiulis A, Turner MA, Zhao W, De Cock P, de Wildt SN, Allegaert K, van den Anker J (2020)
Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology
Eur J Pediatr
DOI 10.1007/s00431-019-03556-9, PubMed 31897842

Skari H, Urdal A, Hagen TS, Bjerre A, Aksnes G (2020)
Kirurgisk behandling ved urininkontinens hos barn
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.18.0536, PubMed 32192254

Skjerven HO, Rehbinder EM, Vettukattil R, LeBlanc M, Granum B, Haugen G, Hedlin G, Landrø L, Marsland BJ, Rudi K, Sjøborg KD, Söderhäll C, Staff AC, Carlsen KH, Asarnoj A, Bains KES, Carlsen OCL, Endre KMA, Granlund PA, Hermansen JU, Gudmundsdóttir HK, Hilde K, Håland G, Kreyberg I, Olsen IC et al. (2020)
Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial
Lancet, 395 (10228), 951-961
DOI 10.1016/S0140-6736(19)32983-6, PubMed 32087121

Stadskleiv K (2020)
Cognitive functioning in children with cerebral palsy
Dev Med Child Neurol, 62 (3), 283-289
DOI 10.1111/dmcn.14463, PubMed 32010976

Stensvold E, Stadskleiv K, Myklebust TÅ, Wesenberg F, Helseth E, Bechensteen AG, Brandal P (2020)
Unmet rehabilitation needs in 86% of Norwegian paediatric embryonal brain tumour survivors
Acta Paediatr
DOI 10.1111/apa.15188, PubMed 31977119

Sumathipala DS, Misceo D, Larsen SM, Barøy T, Gamage TH, Frengen E, Strømme P (2020)
A girl with a neurodevelopmental syndrome, adducted thumbs and frequent infections caused by novel homozygous variant in DEAF1
Clin Dysmorphol, 29 (2), 107-110
DOI 10.1097/MCD.0000000000000314, PubMed 31929336

Tanaka Y, Cakir B, Xiang Y, Sullivan GJ, Park IH (2020)
Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain
Cell Rep, 30 (6), 1682-1689.e3
DOI 10.1016/j.celrep.2020.01.038, PubMed 32049002

Thomassen RA, Kvammen JA, Sæland C, Kjeserud C, Eikeland J, Juliusson PB, Bentsen BS, Henriksen C (2020)
Micronutrients in paediatric Intestinal Failure Patients receiving home parenteral nutrition
Clin Nutr (in press)
DOI 10.1016/j.clnu.2020.02.039, PubMed 32204976

Thorsteinsdottir H, Salvador CL, Mjøen G, Lie A, Sugulle M, Tøndel C, Brun A, Almaas R, Bjerre A (2020)
Growth Differentiation Factor 15 in Children with Chronic Kidney Disease and after Renal Transplantation
Dis Markers, 2020, 6162892
DOI 10.1155/2020/6162892, PubMed 32089755

Tillerås KH, Kjoelaas SH, Dramstad E, Feragen KB, von der Lippe C (2020)
Psychological reactions to predictive genetic testing for Huntington's disease: A qualitative study
J Genet Couns (in press)
DOI 10.1002/jgc4.1245, PubMed 32162754

Tuomilehto J, Ogle GD, Lund-Blix NA, Stene LC (2020)
Update on Worldwide Trends in Occurrence of Childhood Type 1 Diabetes in 2020
Pediatr Endocrinol Rev, 17 (Suppl 1), 198-209
DOI 10.17458/per.vol17.2020.tol.epidemiologychildtype1diabetes, PubMed 32208564

van Walsem MR, Howe EI, Perrin PB, Sigurdardottir S, Røe C, Sveen U, Lu J, Forslund MV, Andelic N (2020)
Trajectories of self-reported competency up to 10 years following moderate-to-severe traumatic brain injury
Brain Inj, 34 (3), 335-342
DOI 10.1080/02699052.2019.1704061, PubMed 31928233

Villanger GD, Ystrom E, Engel SM, Longnecker MP, Pettersen R, Rowe AD, Reichborn-Kjennerud T, Aase H (2020)
Neonatal thyroid-stimulating hormone and association with attention-deficit/hyperactivity disorder
Paediatr Perinat Epidemiol
DOI 10.1111/ppe.12643, PubMed 32072662

Warris A, Pana ZD, Oletto A, Lundin R, Castagnola E, Lehrnbecher T, Groll AH, Roilides E, Andersen CT, Arendrup MC, Arsenijevic VA, Bianchini S, von Both U, Chmelnik M, Controzzi T, Emonts M, Esposito S, Ferreras-Antolin L, Henriet S, Iosifidis E, Irwin A, Kopsidas J, Lagrou K, Lyall H, Casteleiro AM et al. (2020)
Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study
Pediatr Infect Dis J, 39 (2), 114-120
DOI 10.1097/INF.0000000000002530, PubMed 31725552

Weider T, Richardson SJ, Morgan NG, Paulsen TH, Dahl-Jørgensen K, Hammerstad SS (2020)
Upregulation of HLA Class I and Antiviral Tissue Responses in Hashimoto's Thyroiditis
Thyroid, 30 (3), 432-442
DOI 10.1089/thy.2019.0607, PubMed 31910110

Wik G, Jortveit J, Sitras V, Døhlen G, Rønnestad AE, Holmstrøm H (2020)
Severe congenital heart defects: incidence, causes and time trends of preoperative mortality in Norway
Arch Dis Child (in press)
DOI 10.1136/archdischild-2019-317581, PubMed 32051128

Willasch AM, Peters C, Sedláček P, Dalle JH, Kitra-Roussou V, Yesilipek A, Wachowiak J, Lankester A, Prete A, Hamidieh AA, Ifversen M, Buechner J, Kriván G, Hamladji RM, Diaz-de-Heredia C, Skorobogatova E, Michel G, Locatelli F, Bertaina A, Veys P, Dupont S, Or R, Güngör T, Aleinikova O, Sufliarska S et al. (2020)
Myeloablative conditioning for allo-HSCT in pediatric ALL: FTBI or chemotherapy?-A multicenter EBMT-PDWP study
Bone Marrow Transplant (in press)
DOI 10.1038/s41409-020-0854-0, PubMed 32203263

Zasada M, Madetko-Talowska A, Revhaug C, Rognlien AGW, Baumbusch LO, Książek T, Szewczyk K, Grabowska A, Bik-Multanowski M, Józef Pietrzyk J, Kwinta P, Didrik Saugstad O (2020)
Transcriptome analysis reveals dysregulation of genes involved in oxidative phosphorylation in a murine model of retinopathy of prematurity
Pediatr Res
DOI 10.1038/s41390-020-0793-x, PubMed 32053824

Zelihić D, Hjardemaal FR, Lippe CV (2020)
Caring for a child with Bardet-Biedl syndrome: A qualitative study of the parental experiences of daily coping and support
Eur J Med Genet, 103856 (in press)
DOI 10.1016/j.ejmg.2020.103856, PubMed 31972368

 
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