Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Division of Head, Neck and Reconstructive Surgery

43 publications found

Aqrawi LA, Galtung HK, Guerreiro EM, Øvstebø R, Thiede B, Utheim TP, Chen X, Utheim ØA, Palm Ø, Skarstein K, Jensen JL (2019)
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Arthritis Res Ther, 21 (1), 181
DOI 10.1186/s13075-019-1961-4, PubMed 31366407

Blom K, Jørstad ØK, Bragadóttir R (2019)
Endophthalmitis in Oslo, Norway
Acta Ophthalmol (in press)
DOI 10.1111/aos.14028, PubMed 30816017

Botten N, Hodges RR, Li D, Bair JA, Shatos MA, Utheim TP, Serhan CN, Dartt DA (2019)
Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells
FASEB J, 33 (7), 8468-8478
DOI 10.1096/fj.201802467R, PubMed 31013438

Brandstorp-Boesen J, Zätterström U, Evensen JF, Boysen M (2019)
Value of patient-reported symptoms in the follow up of patients potentially cured of laryngeal carcinoma
J Laryngol Otol, 133 (6), 508-514
DOI 10.1017/S0022215119000677, PubMed 31006407

Dalby M, Kristianslund O, Drolsum L (2019)
Long-term outcomes after surgery of late in-the-bag intraocular lens dislocation: a randomized clinical trial
Am J Ophthalmol (in press)
DOI 10.1016/j.ajo.2019.05.030, PubMed 31194950

de Rodez Benavent SA, Nygaard GO, Nilsen KB, Etholm L, Sowa P, Wendel-Haga M, Harbo HF, Drolsum L, Laeng B, Kerty E, Celius EG (2019)
Neurodegenerative Interplay of Cardiovascular Autonomic Dysregulation and the Retina in Early Multiple Sclerosis
Front Neurol, 10, 507
DOI 10.3389/fneur.2019.00507, PubMed 31156539

Djirackor L, Kalirai H, Coupland SE, Petrovski G (2019)
CD166high Uveal Melanoma Cells Represent a Subpopulation With Enhanced Migratory Capacity
Invest Ophthalmol Vis Sci, 60 (7), 2696-2704
DOI 10.1167/iovs.18-26431, PubMed 31242292

Eidet JR, Biernat D, Dahlberg D, Wiedmann MKH, Jorstad OK (2019)
Foster Kennedy syndrome
Tidsskr. Nor. Laegeforen., 139 (10), 941-943

Eidet JR, Biernat D, Dahlberg D, Wiedmann MKH, Jørstad ØK (2019)
Foster Kennedys syndrom
Tidsskr Nor Laegeforen, 139 (10)
DOI 10.4045/tidsskr.18.0719, PubMed 31238653

Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM (2019)
A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
Transl Oncol, 12 (7), 951-958
DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111

Frich L, Bjorkedal BT, Gagama R, Andersson H (2019)
A young woman with white fingers and shortness of breath
Tidsskr. Nor. Laegeforen., 139 (1), 58-62

Hagem AM, Thorsrud A, Sandvik GF, Drolsum L (2019)
Randomized Study of Collagen Cross-Linking With Conventional Versus Accelerated UVA Irradiation Using Riboflavin With Hydroxypropyl Methylcellulose: Two-Year Results
Cornea, 38 (2), 203-209
DOI 10.1097/ICO.0000000000001791, PubMed 30365412

Haukedal CL, Lyxell B, Wie OB (2019)
Health-Related Quality of Life With Cochlear Implants: The Children's Perspective
Ear Hear (in press)
DOI 10.1097/AUD.0000000000000761, PubMed 31408046

Holtan JP, Selmer KK, Heimdal KR, Bragadóttir R (2019)
Inherited retinal disease in Norway - a characterization of current clinical and genetic knowledge
Acta Ophthalmol (in press)
DOI 10.1111/aos.14218, PubMed 31429209

Holtan JP, Teigen K, Aukrust I, Bragadóttir R, Houge G (2019)
Dominant ARL3-related retinitis pigmentosa
Ophthalmic Genet, 40 (2), 124-128
DOI 10.1080/13816810.2019.1586965, PubMed 30932721

Impieri D, Tønseth KA, Hide Ø, Feragen KJB, Høgevold HE, Filip C (2019)
Autologous fat transplantation to the velopharynx for treating mild velopharyngeal insufficiency: A 10-year experience
J Plast Reconstr Aesthet Surg, 72 (8), 1403-1410
DOI 10.1016/j.bjps.2019.03.040, PubMed 31103609

Jacobsen HH, Ringstad G, Jørstad ØK, Moe MC, Sandell T, Eide PK (2019)
The Human Visual Pathway Communicates Directly With the Subarachnoid Space
Invest Ophthalmol Vis Sci, 60 (7), 2773-2780
DOI 10.1167/iovs.19-26997, PubMed 31247084

Jelin E, Wisløff T, Moe MC, Heiberg T (2019)
Psychometric properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ 25) in a Norwegian population of patients with neovascular age-related macular degeneration compared to a control population
Health Qual Life Outcomes, 17 (1), 140
DOI 10.1186/s12955-019-1203-0, PubMed 31412873

Josifovska N, Lumi X, Szatmari-Tóth M, Kristóf E, Russell G, Nagymihály R, Anisimova N, Malyugin B, Kolko M, Ivastinović D, Petrovski G (2019)
Clinical and molecular markers in retinal detachment-From hyperreflective points to stem cells and inflammation
PLoS One, 14 (6), e0217548
DOI 10.1371/journal.pone.0217548, PubMed 31185026

Jouhi S, Jager MJ, de Geus SJR, Desjardins L, Eide NA, Grange JD, Kiilgaard JF, Seregard S, Midena E, Parrozzani R, Caujolle JP, Rospond-Kubiak I, Kivelä TT (2019)
The Small Fatal Choroidal Melanoma Study. A Survey by the European Ophthalmic Oncology Group
Am J Ophthalmol, 202, 100-108
DOI 10.1016/j.ajo.2019.01.031, PubMed 30772347

Kenawy N, Kalirai H, Sacco JJ, Lake SL, Heegaard S, Larsen AC, Finger PT, Milman T, Chin K, Mosci C, Lanza F, Moulin A, Schmitt CA, Caujolle JP, Maschi C, Marinkovic M, Taktak AF, Heimann H, Damato BE, Coupland SE (2019)
Conjunctival melanoma copy number alterations and correlation with mutation status, tumor features, and clinical outcome
Pigment Cell Melanoma Res, 32 (4), 564-575
DOI 10.1111/pcmr.12767, PubMed 30672666

Kristianslund O, Dalby M, Moe MC, Drolsum L (2019)
Cost-effectiveness analysis in a randomized trial of late in-the-bag intraocular lens dislocation surgery: repositioning versus exchange
Acta Ophthalmol (in press)
DOI 10.1111/aos.14108, PubMed 30968572

Lytvynchuk LM, Falkner-Radler CI, Krepler K, Glittenberg CG, Ahmed D, Petrovski G, Lorenz B, Ansari-Shahrezaei S, Binder S (2019)
Dynamic intraoperative optical coherence tomography for inverted internal limiting membrane flap technique in large macular hole surgery
Graefes Arch Clin Exp Ophthalmol, 257 (8), 1649-1659
DOI 10.1007/s00417-019-04364-5, PubMed 31139918

Mandal E, Filip C, Andersson ME, Øgaard B (2019)
Eighteen-Year Follow-Up of 160 Consecutive Individuals Born With Unilateral Cleft Lip or Cleft Lip and Alveolus Treated by the Oslo Cleft Lip and Palate Team
Cleft Palate Craniofac J, 56 (7), 853-859
DOI 10.1177/1055665618820753, PubMed 30686058

Martens C, Goplen FK, Aasen T, Nordfalk KF, Nordahl SHG (2019)
Dizziness handicap and clinical characteristics of posterior and lateral canal BPPV
Eur Arch Otorhinolaryngol, 276 (8), 2181-2189
DOI 10.1007/s00405-019-05459-9, PubMed 31089808

Martinsen T, Pettersen FJ, Kalvøy H, Tronstad C, Kvarstein G, Bakken A, Høgetveit JO, Martinsen ØG, Grimnes S, Frich L (2019)
Electrosurgery and Temperature Increase in Tissue With a Passive Metal Implant
Front Surg, 6, 8
DOI 10.3389/fsurg.2019.00008, PubMed 30915337

Pedersen HR, Neitz M, Gilson SJ, Landsend ECS, Utheim ØA, Utheim TP, Baraas RC (2019)
The Cone Photoreceptor Mosaic in Aniridia: Within-Family Phenotype-Genotype Discordance
Ophthalmol Retina, 3 (6), 523-534
DOI 10.1016/j.oret.2019.01.020, PubMed 31174676

Ræder S, Klyve P, Utheim TP (2019)
Tørre øyne – diagnostikk og behandling
Tidsskr Nor Laegeforen, 139 (11)
DOI 10.4045/tidsskr.18.0752, PubMed 31429248

Råen M, Kristianslund O, Østern AE, Sandvik GF, Drolsum L (2019)
Are Elderly Patients Optimally Corrected with Spectacles in the Longer Term after Cataract Surgery?
Optom Vis Sci, 96 (5), 362-366
DOI 10.1097/OPX.0000000000001371, PubMed 31046019

Schiodt M, Otto S, Fedele S, Bedogni A, Nicolatou-Galitis O, Guggenberger R, Herlofson BB, Ristow O, Kofod T (2019)
Workshop of European task force on medication-related osteonecrosis of the jaw-Current challenges
Oral Dis (in press)
DOI 10.1111/odi.13160, PubMed 31325201

Singer S, Amdal CD, Hammerlid E, Tomaszewska IM, Castro Silva J, Mehanna H, Santos M, Inhestern J, Brannan C, Yarom N, Fullerton A, Pinto M, Arraras JI, Kiyota N, Bonomo P, Sherman AC, Baumann I, Galalae R, Fernandez Gonzalez L, Nicolatou-Galitis O, Abdel-Hafeez Z, Raber-Durlacher J, Schmalz C, Zotti P, Boehm A et al. (2019)
International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV
Head Neck, 41 (6), 1725-1737
DOI 10.1002/hed.25609, PubMed 30636188

Skraastad BK, Knudsen C, Jackson C, Utheim TP, Pripp AH, Tønseth KA (2019)
Quality of life, patient satisfaction and cosmetic outcome after delayed breast reconstruction using DIEP flap: a 10 years' follow-up survey
J Plast Surg Hand Surg, 53 (2), 119-124
DOI 10.1080/2000656X.2018.1562459, PubMed 30654667

Smeland AH, Rustøen T, Naess T, Nybro L, Lundeberg S, Reinertsen H, Diseth TH, Twycross A (2019)
Children's views on postsurgical pain in recovery units in Norway: A qualitative study
J Clin Nurs, 28 (11-12), 2157-2170
DOI 10.1111/jocn.14788, PubMed 30667569

Stadnikova A, Trosan P, Skalicka P, Utheim TP, Jirsova K (2019)
Interleukin-13 maintains the stemness of conjunctival epithelial cell cultures prepared from human limbal explants
PLoS One, 14 (2), e0211861
DOI 10.1371/journal.pone.0211861, PubMed 30742646

Stene-Johansen I, Bragadóttir R, Petrovski BÉ, Petrovski G (2019)
Macular Hole Surgery Using Gas Tamponade-An Outcome from the Oslo Retrospective Cross-Sectional Study
J Clin Med, 8 (5)
DOI 10.3390/jcm8050704, PubMed 31108955

Szatmári-Tóth M, Ilmarinen T, Mikhailova A, Skottman H, Kauppinen A, Kaarniranta K, Kristóf E, Lytvynchuk L, Veréb Z, Fésüs L, Petrovski G (2019)
Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation
Int J Mol Sci, 20 (4)
DOI 10.3390/ijms20040926, PubMed 30791639

Tiedemann D, Mouhammad ZA, Utheim TP, Dartt DA, Heegaard S, Petrovski G, Kolko M (2019)
Conjunctival Goblet Cells, the Overlooked Cells in Glaucoma Treatment
J Glaucoma, 28 (4), 325-333
DOI 10.1097/IJG.0000000000001168, PubMed 30585937

Torkildsen JV, Arciuli J, Wie OB (2019)
Individual differences in statistical learning predict children's reading ability in a semi-transparent orthography
Learn. Individ. Differ., 69, 60-68

Utheim OA, Pasovic L, Raeder S, Eidet JR, Fostad IG, Sehic A, Roald B, de la Paz MF, Lyberg T, Dartt DA, Utheim TP (2019)
Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells
PLoS One, 14 (3), e0212524
DOI 10.1371/journal.pone.0212524, PubMed 30861002

Utjés D, Malmstedt J, Teras J, Drzewiecki K, Gullestad HP, Ingvar C, Eriksson H, Gillgren P (2019)
2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial
Lancet, 394 (10197), 471-477
DOI 10.1016/S0140-6736(19)31132-8, PubMed 31280965

Yazdani M, Elgstøen KBP, Rootwelt H, Shahdadfar A, Utheim ØA, Utheim TP (2019)
Tear Metabolomics in Dry Eye Disease: A Review
Int J Mol Sci, 20 (15)
DOI 10.3390/ijms20153755, PubMed 31374809

Yazdani M, Shahdadfar A, Jackson CJ, Utheim TP (2019)
Hyaluronan-Based Hydrogel Scaffolds for Limbal Stem Cell Transplantation: A Review
Cells, 8 (3)
DOI 10.3390/cells8030245, PubMed 30875861

Øverland B, Berdal H, Akre H (2019)
Obstructive sleep apnea in 2-6 year old children referred for adenotonsillectomy
Eur Arch Otorhinolaryngol, 276 (7), 2097-2104
DOI 10.1007/s00405-019-05362-3, PubMed 31172276

 
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