Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Radiation Biology

30 publications found

Anda S, Grallert B (2019)
Cell-Cycle-Dependent Regulation of Translation: New Interpretations of Old Observations in Light of New Approaches
Bioessays, 41 (8), e1900022
DOI 10.1002/bies.201900022, PubMed 31210378

Berge LAM, Andreassen BK, Stenehjem JS, Larsen IK, Furu K, Juzeniene A, Roscher I, Heir T, Green A, Veierød MB, Robsahm TE (2019)
Cardiovascular, antidepressant and immunosuppressive drug use in relation to risk of cutaneous melanoma: a protocol for a prospective case-control study
BMJ Open, 9 (2), e025246
DOI 10.1136/bmjopen-2018-025246, PubMed 30787091

Boye E, Grallert B (2019)
eIF2α phosphorylation and the regulation of translation
Curr Genet, 66 (2), 293-297
DOI 10.1007/s00294-019-01026-1, PubMed 31485739

Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S (2019)
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
Cell Rep, 28 (7), 1907-1922.e6
DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255

Gaustad JV, Simonsen TG, Wegner CS, Rofstad EK (2019)
Vascularization, Oxygenation, and the Effect of Sunitinib Treatment in Pancreatic Ductal Adenocarcinoma Xenografts
Front Oncol, 9, 845
DOI 10.3389/fonc.2019.00845, PubMed 31555596

Grigalavicius M, Mastrangelopoulou M, Berg K, Arous D, Ménard M, Raabe-Henriksen T, Brondz E, Siem S, Görgen A, Edin NFJ, Malinen E, Theodossiou TA (2019)
Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
Nat Commun, 10 (1), 3986
DOI 10.1038/s41467-019-12042-7, PubMed 31484929

Hansem LMK, Huang R, Wegner CS, Simonsen TG, Gaustad JV, Hauge A, Rofstad EK (2019)
Intratumor Heterogeneity in Interstitial Fluid Pressure in Cervical and Pancreatic Carcinoma Xenografts
Transl Oncol, 12 (8), 1079-1085
DOI 10.1016/j.tranon.2019.05.012, PubMed 31174058

Hauge A, Gaustad JV, Huang R, Simonsen TG, Wegner CS, Andersen LMK, Rofstad EK (2019)
DCE-MRI and Quantitative Histology Reveal Enhanced Vessel Maturation but Impaired Perfusion and Increased Hypoxia in Bevacizumab-Treated Cervical Carcinoma
Int J Radiat Oncol Biol Phys, 104 (3), 666-676
DOI 10.1016/j.ijrobp.2019.03.002, PubMed 30858145

Hauge S, Macurek L, Syljuåsen RG (2019)
p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775
Cell Cycle, 18 (8), 834-847
DOI 10.1080/15384101.2019.1593649, PubMed 30943845

Helgeland H, Sodeland M, Zoric N, Torgersen JS, Grammes F, von Lintig J, Moen T, Kjøglum S, Lien S, Våge DI (2019)
Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color
Sci Rep, 9 (1), 20061
DOI 10.1038/s41598-019-56438-3, PubMed 31882713

Jerjes W, Hamdoon Z, Berg K, Høgset A, Hopper C (2019)
Recurrent chondroblastic osteosarcoma of the right mandible subjected to photochemical internalization
Photodiagnosis Photodyn Ther, 27, 288-290
DOI 10.1016/j.pdpdt.2019.06.018, PubMed 31252139

Jonsson M, Fjeldbo CS, Holm R, Stokke T, Kristensen GB, Lyng H (2019)
Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer
Neoplasia, 21 (4), 353-362
DOI 10.1016/j.neo.2019.01.002, PubMed 30856376

Landsverk HB, Sandquist LE, Sridhara SC, Rødland GE, Sabino JC, de Almeida SF, Grallert B, Trinkle-Mulcahy L, Syljuåsen RG (2019)
Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1
Nucleic Acids Res, 47 (4), 1797-1813
DOI 10.1093/nar/gky1233, PubMed 30541148

Lund KV, Simonsen TG, Kristensen GB, Rofstad EK (2019)
Pharmacokinetic analysis of DCE-MRI data of locally advanced cervical carcinoma with the Brix model
Acta Oncol, 58 (6), 828-837
DOI 10.1080/0284186X.2019.1580386, PubMed 30810443

Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre MR, Fåne A, Gaudernack G, Kvalheim G, Myklebust JH, Inderberg EM, Wälchli S (2019)
NK cells specifically TCR-dressed to kill cancer cells
EBioMedicine, 40, 106-117
DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853

Napoli E, Cessna JT, Fitzgerald R, Pibida L, Collé R, Laureano-Pérez L, Zimmerman BE, Bergeron DE (2019)
Primary standardization of 224Ra activity by liquid scintillation counting
Appl Radiat Isot, 155, 108933
DOI 10.1016/j.apradiso.2019.108933, PubMed 31654881

Ney A, Mahamed I, Garcia-Sampedro A, Selbo PK, Sancho P, MacRobert AJ, Pereira SP, Acedo P (2019)
Combination light-based therapies to treat pancreatic cancer: a proof of concept
PROC SPIE, 11070, UNSP 1107045

Nilsen A, Jonsson M, Aarnes EK, Kristensen GB, Lyng H (2019)
Reference MicroRNAs for RT-qPCR Assays in Cervical Cancer Patients and Their Application to Studies of HPV16 and Hypoxia Biomarkers
Transl Oncol, 12 (3), 576-584
DOI 10.1016/j.tranon.2018.12.010, PubMed 30660934

Olsen CE, Cheung LH, Weyergang A, Berg K, Vallera DA, Rosenblum MG, Selbo PK (2019)
Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization
J Clin Med, 9 (1)
DOI 10.3390/jcm9010068, PubMed 31888091

Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM (2019)
Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
Int J Nanomedicine, 14, 6269-6285
DOI 10.2147/IJN.S208938, PubMed 31496685

Pichard A, Marcatili S, Karam J, Constanzo J, Ladjohounlou R, Courteau A, Jarlier M, Bonnefoy N, Patzke S, Stenberg V, Coopman P, Cartron G, Navarro-Teulon I, Repetto-Llamazares A, Heyerdahl H, Dahle J, Bardiès M, Pouget JP (2019)
The therapeutic effectiveness of 177Lu-lilotomab in B-cell non-Hodgkin lymphoma involves modulation of G2/M cell cycle arrest
Leukemia, 34 (5), 1315-1328
DOI 10.1038/s41375-019-0677-4, PubMed 31836849

Pielke R, Boye E (2019)
Scientific integrity and anti-doping regulation
Int. J. Sport Policy Polit., 11 (2), 295-313

Pielke R, Tucker R, Boye E (2019)
Scientific integrity and the IAAF testosterone regulations
Int. Sports Law J., 19 (1-2), 18-26

Pitman KE, Alluri SR, Kristian A, Aarnes EK, Lyng H, Riss PJ, Malinen E (2019)
Influx rate of 18F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts
Eur J Nucl Med Mol Imaging, 46 (10), 2190-2198
DOI 10.1007/s00259-019-04375-8, PubMed 31264167

Rødland GE, Melhus K, Generalov R, Gilani S, Bertoni F, Dahle J, Syljuåsen RG, Patzke S (2019)
The Dual Cell Cycle Kinase Inhibitor JNJ-7706621 Reverses Resistance to CD37-Targeted Radioimmunotherapy in Activated B Cell Like Diffuse Large B Cell Lymphoma Cell Lines
Front Oncol, 9, 1301
DOI 10.3389/fonc.2019.01301, PubMed 31850205

Shin D, Nguyen L, T Le M, Ju D, N Le J, Berg K, Hirschberg H (2019)
The effects of low irradiance long duration photochemical internalization on glioma spheroids
Photodiagnosis Photodyn Ther, 26, 442-447
DOI 10.1016/j.pdpdt.2019.05.005, PubMed 31075319

Sun CH, Berg K, Hirschberg H (2019)
Photochemical Internalization Enhanced Nonviral Suicide Gene Therapy
Methods Mol Biol, 1895, 165-176
DOI 10.1007/978-1-4939-8922-5_13, PubMed 30539537

Switlyk MD, Salberg UB, Geier OM, Vlatkovic L, Lilleby W, Lyng H, Seierstad T (2019)
PTEN Expression in Prostate Cancer: Relationship With Clinicopathologic Features and Multiparametric MRI Findings
AJR Am J Roentgenol, 212 (6), 1206-1214
DOI 10.2214/AJR.18.20743, PubMed 30888866

Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
Nanotoxicology, 13 (6), 761-782
DOI 10.1080/17435390.2019.1576238, PubMed 30760074

Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194

 
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