Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2018 from OUS - Department of Radiation Biology

26 publications found

Bøe CA, Håland TW, Boye E, Syljuåsen RG, Grallert B (2018)
A novel role for ATR/Rad3 in G1 phase
Sci Rep, 8 (1), 6880
DOI 10.1038/s41598-018-25238-6, PubMed 29720710

Eng MS, Kaur J, Prasmickaite L, Engesæter BØ, Weyergang A, Skarpen E, Berg K, Rosenblum MG, Mælandsmo GM, Høgset A, Ferrone S, Selbo PK (2018)
Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
Photochem Photobiol Sci, 17 (5), 539-551
DOI 10.1039/C7PP00358G, PubMed 29565434

Fenaroli F, Repnik U, Xu Y, Johann K, Van Herck S, Dey P, Skjeldal FM, Frei DM, Bagherifam S, Kocere A, Haag R, De Geest BG, Barz M, Russell DG, Griffiths G (2018)
Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models
ACS Nano, 12 (8), 8646-8661
DOI 10.1021/acsnano.8b04433, PubMed 30081622

Haug M, Brede G, Håkerud M, Nedberg AG, Gederaas OA, Flo TH, Edwards VT, Selbo PK, Høgset A, Halaas Ø (2018)
Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination
Front Immunol, 9, 650
DOI 10.3389/fimmu.2018.00650, PubMed 29670624

Hauge A, Wegner CS, Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK (2018)
Diffusion-Weighted MRI Is Insensitive to Changes in the Tumor Microenvironment Induced by Antiangiogenic Therapy
Transl Oncol, 11 (5), 1128-1136
DOI 10.1016/j.tranon.2018.07.005, PubMed 30036782

Hirschberg H, Berg K, Peng Q (2018)
Photodynamic therapy mediated immune therapy of brain tumors
Neuroimmunol Neuroinflamm, 5
DOI 10.20517/2347-8659.2018.31, PubMed 30221185

Hompland T, Hole KH, Ragnum HB, Aarnes EK, Vlatkovic L, Lie AK, Patzke S, Brennhovd B, Seierstad T, Lyng H (2018)
Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Cancer Res, 78 (16), 4774-4785
DOI 10.1158/0008-5472.CAN-17-3806, PubMed 29945958

Huang R, Rofstad EK (2018)
Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma
J Exp Clin Cancer Res, 37 (1), 92
DOI 10.1186/s13046-018-0763-x, PubMed 29703238

Juzeniene A, Bernoulli J, Suominen M, Halleen J, Larsen RH (2018)
Antitumor Activity of Novel Bone-seeking, α-emitting 224Ra-solution in a Breast Cancer Skeletal Metastases Model
Anticancer Res, 38 (4), 1947-1955
DOI 10.21873/anticanres.12432, PubMed 29599310

Lam KC, Vyshenska D, Hu J, Rodrigues RR, Nilsen A, Zielke RA, Brown NS, Aarnes EK, Sikora AE, Shulzhenko N, Lyng H, Morgun A (2018)
Transkingdom network reveals bacterial players associated with cervical cancer gene expression program
PeerJ, 6, e5590
DOI 10.7717/peerj.5590, PubMed 30294508

Landsverk HB, Sandquist LE, Sridhara SC, Rødland GE, Sabino JC, de Almeida SF, Grallert B, Trinkle-Mulcahy L, Syljuåsen RG (2018)
Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1
Nucleic Acids Res (in press)
DOI 10.1093/nar/gky1233, PubMed 30541148

Leibfarth S, Winter RM, Lyng H, Zips D, Thorwarth D (2018)
Potentials and challenges of diffusion-weighted magnetic resonance imaging in radiotherapy
Clin Transl Radiat Oncol, 13, 29-37
DOI 10.1016/j.ctro.2018.09.002, PubMed 30294681

Mastrangelopoulou M, Grigalavicius M, Berg K, Ménard M, Theodossiou TA (2018)
Cytotoxic and Photocytotoxic Effects of Cercosporin on Human Tumor Cell Lines
Photochem Photobiol (in press)
DOI 10.1111/php.12997, PubMed 30107033

Mikalsen SG, Mikalsen LTG, Sandvik JA, Aarnes EK, Fenne S, Flatmark K, Lyng H, Edin NFJ, Pettersen EO (2018)
Low dose-rate irradiation with [3H]-labelled valine to selectively target hypoxic cells in a human colorectal cancer xenograft model
Acta Oncol, 57 (9), 1216-1224
DOI 10.1080/0284186X.2018.1457223, PubMed 29630428

Repetto-Llamazares AHV, Malenge MM, O'Shea A, Eiríksdóttir B, Stokke T, Larsen RH, Dahle J (2018)
Combination of 177 Lu-lilotomab with rituximab significantly improves the therapeutic outcome in preclinical models of non-Hodgkin's lymphoma
Eur J Haematol, 101 (4), 522-531
DOI 10.1111/ejh.13139, PubMed 29993152

Shearer RF, Frikstad KM, McKenna J, McCloy RA, Deng N, Burgess A, Stokke T, Patzke S, Saunders DN (2018)
The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia
Mol Biol Cell, 29 (13), 1542-1554
DOI 10.1091/mbc.E17-04-0248, PubMed 29742019

Sideratou Z, Agathokleous M, Theodossiou TA, Tsiourvas D (2018)
Functionalized Hyperbranched Polyethylenimines as Thermosensitive Drug Delivery Nanocarriers with Controlled Transition Temperatures
Biomacromolecules, 19 (2), 315-328
DOI 10.1021/acs.biomac.7b01325, PubMed 29313672

Simonsen TG, Lund KV, Hompland T, Kristensen GB, Rofstad EK (2018)
DCE-MRI-Derived Measures of Tumor Hypoxia and Interstitial Fluid Pressure Predict Outcomes in Cervical Carcinoma
Int J Radiat Oncol Biol Phys, 102 (4), 1193-1201
DOI 10.1016/j.ijrobp.2018.04.035, PubMed 29859790

Stonyte V, Boye E, Grallert B (2018)
Regulation of global translation during the cell cycle
J Cell Sci, 131 (17)
DOI 10.1242/jcs.220327, PubMed 30072440

Våtsveen TK, Myhre MR, Steen CB, Wälchli S, Lingjærde OC, Bai B, Dillard P, Theodossiou TA, Holien T, Sundan A, Inderberg EM, Smeland EB, Myklebust JH, Oksvold MP (2018)
Artesunate shows potent anti-tumor activity in B-cell lymphoma
J Hematol Oncol, 11 (1), 23
DOI 10.1186/s13045-018-0561-0, PubMed 29458389

Wegner CS, Hauge A, Andersen LMK, Huang R, Simonsen TG, Gaustad JV, Rofstad EK (2018)
Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation
Oncotarget, 9 (30), 21036-21051
DOI 10.18632/oncotarget.24783, PubMed 29765518

Wegner CS, Hauge A, Simonsen TG, Gaustad JV, Andersen LMK, Rofstad EK (2018)
DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts
Neoplasia, 20 (7), 734-744
DOI 10.1016/j.neo.2018.05.006, PubMed 29886124

Westrøm S, Malenge M, Jorstad IS, Napoli E, Bruland ØS, Bønsdorff TB, Larsen RH (2018)
Ra-224 labeling of calcium carbonate microparticles for internal α-therapy: Preparation, stability, and biodistribution in mice
J Labelled Comp Radiopharm, 61 (6), 472-486
DOI 10.1002/jlcr.3610, PubMed 29380410

Weyergang A, Fremstedal AS, Skarpen E, Peng Q, Mohamedali KA, Eng MS, Cheung LH, Rosenblum MG, Waltenberger J, Berg K (2018)
Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
J Control Release, 288, 161-172
DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739

Zach R, Tvaružková J, Schätz M, Tupa O, Grallert B, Prevorovský M (2018)
Mitotic defects in fission yeast lipid metabolism 'cut' mutants are suppressed by ammonium chloride
FEMS Yeast Res, 18 (6)
DOI 10.1093/femsyr/foy064, PubMed 29931271

Zhang X, de Boer L, Heiliegers L, Man-Bovenkerk S, Selbo PK, Drijfhout JW, Høgset A, Zaat SAJ (2018)
Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection
J Control Release, 283, 214-222
DOI 10.1016/j.jconrel.2018.06.004, PubMed 29883696

 
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