Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2017 from OUS - Department of Radiation Biology
33 publications found
Activation of Gcn2 in response to different stresses
PLoS One, 12 (8), e0182143
DOI 10.1371/journal.pone.0182143, PubMed 28771613
Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts
Oncotarget, 8 (29), 48060-48074
DOI 10.18632/oncotarget.18231, PubMed 28624797
Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line
Sci Rep, 7 (1), 5178
DOI 10.1038/s41598-017-05461-3, PubMed 28701707
LUMiC® Endoprosthetic Reconstruction After Periacetabular Tumor Resection: Short-term Results
Clin Orthop Relat Res, 475 (3), 686-695
DOI 10.1007/s11999-016-4805-4, PubMed 27020434
Photodynamic therapy enhances the efficacy of gene-directed enzyme prodrug therapy
Photodiagnosis Photodyn Ther, 18, 140-148
DOI 10.1016/j.pdpdt.2017.02.016, PubMed 28257943
The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles
Transl Oncol, 10 (2), 158-167
DOI 10.1016/j.tranon.2016.12.007, PubMed 28167241
Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts
J Transl Med, 15 (1), 241
DOI 10.1186/s12967-017-1347-9, PubMed 29183378
Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts
BMC Cancer, 17 (1), 411
DOI 10.1186/s12885-017-3404-4, PubMed 28606060
Endosome Targeting meso-Tetraphenylchlorin-Chitosan Nanoconjugates for Photochemical Internalization
Biomacromolecules, 18 (4), 1108-1126
DOI 10.1021/acs.biomac.6b01670, PubMed 28245649
Photochemical internalization in bladder cancer - development of an orthotopic in vivo model
Photochem Photobiol Sci, 16 (11), 1664-1676
DOI 10.1039/c7pp00176b, PubMed 28972608
DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment
J Transl Med, 15 (1), 225
DOI 10.1186/s12967-017-1331-4, PubMed 29100521
Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer
Oncotarget, 8 (62), 105682-105691
DOI 10.18632/oncotarget.22388, PubMed 29285283
Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading
Oncotarget, 8 (7), 10966-10979
DOI 10.18632/oncotarget.14089, PubMed 28030798
TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency
PLoS One, 12 (10), e0185708
DOI 10.1371/journal.pone.0185708, PubMed 28973009
Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts
J Transl Med, 15 (1), 203
DOI 10.1186/s12967-017-1307-4, PubMed 29017512
Cancer stem cells (CSCs), cervical CSCs and targeted therapies
Oncotarget, 8 (21), 35351-35367
DOI 10.18632/oncotarget.10169, PubMed 27343550
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876
MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells
Tumour Biol, 39 (8), 1010428317713671
DOI 10.1177/1010428317713671, PubMed 28789597
Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
Sci Rep, 7 (1), 5081
DOI 10.1038/s41598-017-05086-6, PubMed 28698547
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
J Exp Clin Cancer Res, 36 (1), 187
DOI 10.1186/s13046-017-0662-6, PubMed 29258566
Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer
Acta Oncol, 56 (5), 675-681
DOI 10.1080/0284186X.2017.1294762, PubMed 28447564
Hypoxia in cervical cancer: from biology to imaging
Clin Transl Imaging, 5 (4), 373-388
DOI 10.1007/s40336-017-0238-7, PubMed 28804704
Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity
J Control Release, 268, 120-127
DOI 10.1016/j.jconrel.2017.10.015, PubMed 29042319
Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin
Photodiagnosis Photodyn Ther, 20, 35-47
DOI 10.1016/j.pdpdt.2017.08.010, PubMed 28838761
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290
Molecular Mechanisms of UVA-Induced Melanoma
J Environ Pathol Toxicol Oncol, 36 (3), 217-228
DOI 10.1615/JEnvironPatholToxicolOncol.2017020213, PubMed 29283335
A checkpoint-independent mechanism delays entry into mitosis after UV irradiation
J Cell Sci, 130 (23), 4028-4037
DOI 10.1242/jcs.204693, PubMed 29046339
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
Cell Med, 9 (3), 103-116
DOI 10.3727/215517917X693401, PubMed 28713640
Photochemical internalization (PCI) of bleomycin is equally effective in two dissimilar leiomyosarcoma xenografts in athymic mice
Photodiagnosis Photodyn Ther, 20, 95-106
DOI 10.1016/j.pdpdt.2017.08.015, PubMed 28865875
Photochemical internalization enhanced macrophage delivered chemotherapy
Photodiagnosis Photodyn Ther, 21, 156-162
DOI 10.1016/j.pdpdt.2017.12.002, PubMed 29221858
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy
Redox Biol, 12, 191-197
DOI 10.1016/j.redox.2017.02.018, PubMed 28254657
Autodelineation of cervical cancers using multiparametric magnetic resonance imaging and machine learning
Acta Oncol, 56 (6), 806-812
DOI 10.1080/0284186X.2017.1285499, PubMed 28464746
Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts
Acta Oncol, 56 (12), 1754-1762
DOI 10.1080/0284186X.2017.1343494, PubMed 28661213