Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2014 from OUS - Genetics (Lothe)

11 publications found

Almeida M, Costa VL, Costa NR, Ramalho-Carvalho J, Baptista T, Ribeiro FR, Paulo P, Teixeira MR, Oliveira J, Lothe RA, Lind GE, Henrique R, Jerónimo C (2014)
Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential
J Cell Mol Med, 18 (11), 2287-97
DOI 10.1111/jcmm.12394, PubMed 25211630

Bruun J, Kolberg M, Nesland JM, Svindland A, Nesbakken A, Lothe RA (2014)
Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series
Front Oncol, 4, 118
DOI 10.3389/fonc.2014.00118, PubMed 24904831

Danielsen SA, Eide PW, Nesbakken A, Guren T, Leithe E, Lothe RA (2014)
Portrait of the PI3K/AKT pathway in colorectal cancer
Biochim Biophys Acta, 1855 (1), 104-21
DOI 10.1016/j.bbcan.2014.09.008, PubMed 25450577

Hveem TS, Merok MA, Pretorius ME, Novelli M, Bævre MS, Sjo OH, Clinch N, Liestøl K, Svindland A, Lothe RA, Nesbakken A, Danielsen HE (2014)
Prognostic impact of genomic instability in colorectal cancer
Br J Cancer, 110 (8), 2159-64
DOI 10.1038/bjc.2014.133, PubMed 24642618

Løvf M, Nome T, Bruun J, Eknaes M, Bakken AC, Mpindi JP, Kilpinen S, Rognum TO, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2014)
A novel transcript, VNN1-AB, as a biomarker for colorectal cancer
Int J Cancer, 135 (9), 2077-84
DOI 10.1002/ijc.28855, PubMed 24687856

Sirnes S, Lind GE, Bruun J, Fykerud TA, Mesnil M, Lothe RA, Rivedal E, Kolberg M, Leithe E (2014)
Connexins in colorectal cancer pathogenesis
Int J Cancer, 137 (1), 1-11
DOI 10.1002/ijc.28911, PubMed 24752574

Smebye ML, Sveen A, Haugom L, Davidson B, Tropé CG, Lothe RA, Heim S, Skotheim RI, Micci F (2014)
Chromosome 19 rearrangements in ovarian carcinomas: zinc finger genes are particularly targeted
Genes Chromosomes Cancer, 53 (7), 558-67
DOI 10.1002/gcc.22166, PubMed 24634323

Sveen A, Johannessen B, Teixeira MR, Lothe RA, Skotheim RI (2014)
Transcriptome instability as a molecular pan-cancer characteristic of carcinomas
BMC Genomics, 15, 672
DOI 10.1186/1471-2164-15-672, PubMed 25109687

Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2014)
Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
Methods Mol Biol, 1105, 315-24
DOI 10.1007/978-1-62703-739-6_25, PubMed 24623239

Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2014)
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int J Cancer, 136 (4), 844-53
DOI 10.1002/ijc.29039, PubMed 24948044

Vedeld HM, Skotheim RI, Lothe RA, Lind GE (2014)
The recently suggested intestinal cancer stem cell marker DCLK1 is an epigenetic biomarker for colorectal cancer
Epigenetics, 9 (3), 346-50
DOI 10.4161/epi.27582, PubMed 24384857

 
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