Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2018 from OUS - Department of Anesthesiology

61 publications found

Anthon CT, Granholm A, Perner A, Laake JH, Møller MH (2018)
No firm evidence that lack of blinding affects estimates of mortality in randomized clinical trials of intensive care interventions: a systematic review and meta-analysis
J Clin Epidemiol, 100, 71-81
DOI 10.1016/j.jclinepi.2018.04.016, PubMed 29705093

Anthon CT, Granholm A, Perner A, Laake JH, Møller MH (2018)
Bias and sample size in intensive care unit trials: Protocol for a meta-epidemiological study
Acta Anaesthesiol Scand, 63 (1), 117-121
DOI 10.1111/aas.13258, PubMed 30203472

Asprusten TT, Sulheim D, Fagermoen E, Winger A, Skovlund E, Wyller VB (2018)
Systemic exertion intolerance disease diagnostic criteria applied on an adolescent chronic fatigue syndrome cohort: evaluation of subgroup differences and prognostic utility
BMJ Paediatr Open, 2 (1), e000233
DOI 10.1136/bmjpo-2017-000233, PubMed 29637195

Barke A, Korwisi B, Casser HR, Fors EA, Geber C, Schug SA, Stubhaug A, Ushida T, Wetterling T, Rief W, Treede RD (2018)
Pilot field testing of the chronic pain classification for ICD-11: the results of ecological coding
BMC Public Health, 18 (1), 1239
DOI 10.1186/s12889-018-6135-9, PubMed 30404594

Breivik H, Norum H, Fenger-Eriksen C, Alahuhta S, Vigfússon G, Thomas O, Lagerkranser M (2018)
Reducing risk of spinal haematoma from spinal and epidural pain procedures
Scand J Pain, 18 (2), 129-150
DOI 10.1515/sjpain-2018-0041, PubMed 29794308

Dumont KA, Kvitting JE, Karlsen JS, Remme EW, Hausken J, Lundblad R, Fiane AE, Urheim S (2018)
Validation of a Holographic Display for Quantification of Mitral Annular Dynamics by Three-Dimensional Echocardiography
J Am Soc Echocardiogr (in press)
DOI 10.1016/j.echo.2018.08.010, PubMed 30293779

Düring J, Dankiewicz J, Cronberg T, Hassager C, Hovdenes J, Kjaergaard J, Kuiper M, Nielsen N, Pellis T, Stammet P, Vulto J, Wanscher M, Wise M, Åneman A, Friberg H (2018)
Lactate, lactate clearance and outcome after cardiac arrest: A post-hoc analysis of the TTM-Trial
Acta Anaesthesiol Scand, 62 (10), 1436-1442
DOI 10.1111/aas.13172, PubMed 29926901

Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353, PubMed 28657937

Godt JC, Eken T, Schulz A, Johansen CK, Aarsnes A, Dormagen JB (2018)
Triple-split-bolus versus single-bolus CT in abdominal trauma patients: a comparative study
Acta Radiol, 59 (9), 1038-1044
DOI 10.1177/0284185117752522, PubMed 29350048

Halaas NB, Blennow K, Idland AV, Wyller TB, Ræder J, Frihagen F, Staff AC, Zetterberg H, Watne LO (2018)
Neurofilament Light in the Serum and Cerebrospinal Fluid of Hip Fracture Patients with Delirium
Dement Geriatr Cogn Disord, 46 (5-6), 346-357 (in press)
DOI 10.1159/000494754, PubMed 30522125

Hansson P, Jensen TS, Kvarstein G, Strömberg M (2018)
Pain-relieving effectiveness, quality of life and tolerability of repeated capsaicin 8% patch treatment of peripheral neuropathic pain in Scandinavian clinical practice
Eur J Pain, 22 (5), 941-950
DOI 10.1002/ejp.1180, PubMed 29388284

Hardy S, Fattah S, Wisborg T, Raatiniemi L, Staff T, Rehn M (2018)
Systematic reporting to improve the emergency medical response to major incidents: a pilot study
BMC Emerg Med, 18 (1), 4
DOI 10.1186/s12873-018-0153-x, PubMed 29368642

Hassel B, Mariussen E, Idland AV, Dahl GT, Ræder J, Frihagen F, Berg JP, Chaudhry FA, Wyller TB, Watne LO (2018)
CSF sodium at toxic levels precedes delirium in hip fracture patients
Neurotoxicology, 69, 11-16
DOI 10.1016/j.neuro.2018.08.010, PubMed 30149051

Haugland H, Uleberg O, Klepstad P, Krüger A, Rehn M (2018)
Quality measurement in physician-staffed emergency medical services: a systematic literature review
Int J Qual Health Care (in press)
DOI 10.1093/intqhc/mzy106, PubMed 29767795

Hyler S, Espinoza A, Skulstad H, Fosse E, Steinar Halvorsen P (2018)
Corrigendum to 'Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor' [Eur J Cardiothorac Surg 2014;46:313-20]
Eur J Cardiothorac Surg, 54 (5), 968
DOI 10.1093/ejcts/ezy340, PubMed 30295773

Isasi I, Irusta U, Aramendi E, Ayala U, Alonso E, Kramer-Johansen J, Eftestol T (2018)
A Multistage Algorithm for ECG Rhythm Analysis during Piston Driven Mechanical Chest Compressions
IEEE Trans Biomed Eng (in press)
DOI 10.1109/TBME.2018.2827304, PubMed 29993407

Isasi I, Irusta U, Elola A, Aramendi E, Ayala U, Alonso E, Kramer-Johansen J, Eftestol T (2018)
A Machine Learning Shock Decision Algorithm for use during Piston-driven Chest Compressions
IEEE Trans Biomed Eng (in press)
DOI 10.1109/TBME.2018.2878910, PubMed 30387719

Juel BE, Romundstad L, Kolstad F, Storm JF, Larsson PG (2018)
Distinguishing Anesthetized from Awake State in Patients: A New Approach Using One Second Segments of Raw EEG
Front Hum Neurosci, 12, 40
DOI 10.3389/fnhum.2018.00040, PubMed 29515381

Kaspersen ER, Ræder J, Dahl V (2018)
Guidelines for treatment of sepsis
Tidsskr Nor Laegeforen, 138 (4)
DOI 10.4045/tidsskr.17.0493, PubMed 29460575

Kongsgaard UE, Holtan A, Perner A (2018)
Changes in colloid solution sales in Nordic countries
Acta Anaesthesiol Scand, 62 (4), 522-530
DOI 10.1111/aas.13057, PubMed 29315469

Krohg A, Ullensvang K, Rosseland LA, Langesæter E, Sauter AR (2018)
The Analgesic Effect of Ultrasound-Guided Quadratus Lumborum Block After Cesarean Delivery: A Randomized Clinical Trial
Anesth Analg, 126 (2), 559-565
DOI 10.1213/ANE.0000000000002648, PubMed 29135590

Langerud AK, Rustøen T, Brunborg C, Kongsgaard U, Stubhaug A (2018)
Prevalence, Location, and Characteristics of Chronic Pain in Intensive Care Survivors
Pain Manag Nurs, 19 (4), 366-376
DOI 10.1016/j.pmn.2017.11.005, PubMed 29455923

Langerud AK, Rustøen T, Småstuen MC, Kongsgaard U, Stubhaug A (2018)
Health-related quality of life in intensive care survivors: Associations with social support, comorbidity, and pain interference
PLoS One, 13 (6), e0199656
DOI 10.1371/journal.pone.0199656, PubMed 29940026

Lybeck A, Cronberg T, Aneman A, Hassager C, Horn J, Hovdenes J, Kjærgaard J, Kuiper M, Wanscher M, Stammet P, Wise MP, Nielsen N, Ullén S, Friberg H, TTM-trial investigators (2018)
Time to awakening after cardiac arrest and the association with target temperature management
Resuscitation, 126, 166-171
DOI 10.1016/j.resuscitation.2018.01.027, PubMed 29371115

Madah-Amiri D, Skulberg AK, Braarud AC, Dale O, Heyerdahl F, Lobmaier P, Clausen T (2018)
Ambulance-attended opioid overdoses: An examination into overdose locations and the role of a safe injection facility
Subst Abus, 1-6 (in press)
DOI 10.1080/08897077.2018.1485130, PubMed 29949448

Myhre M, Jacobsen HB, Andersson S, Stubhaug A (2018)
Cognitive Effects of Perioperative Pregabalin: Secondary Exploratory Analysis of a Randomized Placebo-controlled Study
Anesthesiology (in press)
DOI 10.1097/ALN.0000000000002473, PubMed 30335626

Møller MH, Granholm A, Junttila E, Haney M, Oscarsson-Tibblin A, Haavind A, Laake JH, Wilkman E, Sverrisson KÖ, Perner A (2018)
Scandinavian SSAI clinical practice guideline on choice of inotropic agent for patients with acute circulatory failure
Acta Anaesthesiol Scand, 62 (4), 420-450
DOI 10.1111/aas.13089, PubMed 29479665

Nolan JP, Berg RA, Callaway CW, Morrison LJ, Nadkarni V, Perkins GD, Sandroni C, Skrifvars MB, Soar J, Sunde K, Cariou A (2018)
The present and future of cardiac arrest care: international experts reach out to caregivers and healthcare authorities
Intensive Care Med, 44 (6), 823-832
DOI 10.1007/s00134-018-5230-9, PubMed 29860705

Nøstdahl T, Bernklev T, Fredheim OM, Paddison JS, Raeder J (2018)
Defining the cut-off point of clinically significant postoperative fatigue in three common fatigue scales
Qual Life Res (in press)
DOI 10.1007/s11136-018-2068-0, PubMed 30506178

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE (2018)
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440

Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GØ, Yndestad A (2018)
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279

Ottestad W, Kåsin JI, Høiseth LØ (2018)
Arterial Oxygen Saturation, Pulse Oximetry, and Cerebral and Tissue Oximetry in Hypobaric Hypoxia
Aerosp Med Hum Perform, 89 (12), 1045-1049
DOI 10.3357/AMHP.5173.2018, PubMed 30487024

Raven TJL, Lothe LR, Sandbæk G, Eken T (2018)
Precision implantation with positional confirmation of fine-wire EMG electrodes in the deep posterior neck muscles
J Electromyogr Kinesiol, 43, 162-167
DOI 10.1016/j.jelekin.2018.10.001, PubMed 30316112

Reid BO, Rehn M, Uleberg O, Krüger AJ (2018)
Physician-provided prehospital critical care, effect on patient physiology dynamics and on-scene time
Eur J Emerg Med, 25 (2), 114-119
DOI 10.1097/MEJ.0000000000000432, PubMed 27879534

Reid BO, Rehn M, Uleberg O, Pleym LEN, Krüger AJ (2018)
Inter-disciplinary cooperation in a physician-staffed emergency medical system
Acta Anaesthesiol Scand, 62 (7), 1007-1013
DOI 10.1111/aas.13112, PubMed 29569383

Reine E, Rustøen T, Raeder J, Aase K (2018)
Postoperative patient handovers-Variability in perceptions of quality: A qualitative focus group study
J Clin Nurs (in press)
DOI 10.1111/jocn.14662, PubMed 30183113

Ringh M, Hollenberg J, Palsgaard-Moeller T, Svensson L, Rosenqvist M, Lippert FK, Wissenberg M, Malta Hansen C, Claesson A, Viereck S, Zijlstra JA, Koster RW, Herlitz J, Blom MT, Kramer-Johansen J, Tan HL, Beesems SG, Hulleman M, Olasveengen TM, Folke F, COSTA study group (research collaboration between Copenhagen, Oslo, STockholm, and Amsterdam) (2018)
The challenges and possibilities of public access defibrillation
J Intern Med, 283 (3), 238-256
DOI 10.1111/joim.12730, PubMed 29331055

Røislien J, Søvik S, Eken T (2018)
Seasonality in trauma admissions - Are daylight and weather variables better predictors than general cyclic effects?
PLoS One, 13 (2), e0192568
DOI 10.1371/journal.pone.0192568, PubMed 29425210

Samdal M, Haugland HH, Fjeldet C, Rehn M, Sandberg M (2018)
Static Rope Evacuation by Helicopter Emergency Medical Services in Rescue Operations in Southeast Norway
Wilderness Environ Med, 29 (3), 315-324
DOI 10.1016/j.wem.2018.03.010, PubMed 29908723

Schalit I, Espinoza A, Pettersen FJ, Thiara APS, Karlsen H, Sørensen G, Fosse E, Fiane AE, Halvorsen PS (2018)
Accelerometer Detects Pump Thrombosis and Thromboembolic Events in an In vitro HVAD Circuit
ASAIO J, 64 (5), 601-609
DOI 10.1097/MAT.0000000000000699, PubMed 29088023

Schjørring OL, Toft-Petersen AP, Kusk KH, Mouncey P, Sørensen EE, Berezowicz P, Bestle MH, Bülow HH, Bundgaard H, Christensen S, Iversen SA, Kirkeby-Garstad I, Krarup KB, Kruse M, Laake JH, Liboriussen L, Laebel RL, Okkonen M, Poulsen LM, Russell L, Sjövall F, Sunde K, Søreide E, Waldau T, Walli AR et al. (2018)
Intensive care doctors' preferences for arterial oxygen tension levels in mechanically ventilated patients
Acta Anaesthesiol Scand, 62 (10), 1443-1451
DOI 10.1111/aas.13171, PubMed 29926908

Sjoeen GH, Falk RS, Hauge TH, Langesaeter E (2018)
Haemodynamic stability after paracervical block: A randomized, controlled, double-blind study comparing bupivacaine-adrenaline with bupivacaine
Acta Anaesthesiol Scand (in press)
DOI 10.1111/aas.13259, PubMed 30203440

Skulberg AK, Tylleskar I, Nilsen T, Skarra S, Salvesen Ø, Sand T, Loftsson T, Dale O (2018)
Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers
Eur J Clin Pharmacol, 74 (7), 873-883
DOI 10.1007/s00228-018-2443-3, PubMed 29568976

Skåre C, Boldingh AM, Kramer-Johansen J, Calisch TE, Nakstad B, Nadkarni V, Olasveengen TM, Niles DE (2018)
Video performance-debriefings and ventilation-refreshers improve quality of neonatal resuscitation
Resuscitation, 132, 140-146
DOI 10.1016/j.resuscitation.2018.07.013, PubMed 30009926

Skåre C, Calisch TE, Saeter E, Rajka T, Boldingh AM, Nakstad B, Niles DE, Kramer-Johansen J, Olasveengen TM (2018)
Implementation and effectiveness of a video-based debriefing programme for neonatal resuscitation
Acta Anaesthesiol Scand, 62 (3), 394-403
DOI 10.1111/aas.13050, PubMed 29315458

Solheim N, Gregersen I, Halvorsen B, Bjerkeli V, Stubhaug A, Gordh T, Rosseland LA (2018)
Randomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery
Acta Anaesthesiol Scand, 62 (6), 829-838
DOI 10.1111/aas.13104, PubMed 29512121

Staer-Jensen H, Sunde K, Nakstad ER, Eritsland J, Andersen GØ (2018)
Comparison of three haemodynamic monitoring methods in comatose post cardiac arrest patients
Scand Cardiovasc J, 52 (3), 141-148
DOI 10.1080/14017431.2018.1450992, PubMed 29544369

Stafseth SK, Tønnessen TI, Fagerström L (2018)
Association between patient classification systems and nurse staffing costs in intensive care units: An exploratory study
Intensive Crit Care Nurs, 45, 78-84
DOI 10.1016/j.iccn.2018.01.007, PubMed 29402682

Stafseth SK, Tønnessen TI, My Diep L, Fagerstrøm L (2018)
Testing the Reliability and Validity of the Nursing Activities Score in Critical Care Nursing
J Nurs Meas, 26 (1), 142-162
DOI 10.1891/1061-3749.26.1.142, PubMed 29724285

Strand-Amundsen RJ, Reims HM, Reinholt FP, Ruud TE, Yang R, Høgetveit JO, Tønnessen TI (2018)
Ischemia/reperfusion injury in porcine intestine - Viability assessment
World J Gastroenterol, 24 (18), 2009-2023
DOI 10.3748/wjg.v24.i18.2009, PubMed 29760544

Strand-Amundsen RJ, Tronstad C, Kalvøy H, Ruud TE, Høgetveit JO, Martinsen ØG, Tønnessen TI (2018)
Small intestinal ischemia and reperfusion-bioimpedance measurements
Physiol Meas, 39 (2), 025001
DOI 10.1088/1361-6579/aaa576, PubMed 29303488

Strand-Amundsen RJ, Tronstad C, Reims HM, Reinholt FP, Høgetveit JO, Tønnessen TI (2018)
Machine learning for intraoperative prediction of viability in ischemic small intestine
Physiol Meas, 39 (10), 105011
DOI 10.1088/1361-6579/aae0ea, PubMed 30207981

Sundby ØH, Irgens I, Høiseth LØ, Mathiesen I, Lundgaard E, Haugland H, Weedon-Fekjær H, Sundhagen JO, Sandbæk G, Hisdal J (2018)
Intermittent mild negative pressure applied to the lower limb in patients with spinal cord injury and chronic lower limb ulcers: a crossover pilot study
Spinal Cord, 56 (4), 372-381
DOI 10.1038/s41393-018-0080-4, PubMed 29497177

Svalebjørg M, Storm H, Olsen RB, Bugge JF (2018)
Measurement of skin conductance responses to evaluate procedural pain in the perioperative setting
Scand J Pain, 18 (4), 639-644
DOI 10.1515/sjpain-2018-0088, PubMed 30048238

Thomas AM, Schjalm C, Nilsson PH, Lindenskov PHH, Rørtveit R, Solberg R, Saugstad OD, Berglund MM, Strömberg P, Lau C, Espevik T, Jansen JH, Castellheim A, Mollnes TE, Barratt-Due A (2018)
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome
Neonatology, 113 (4), 322-330
DOI 10.1159/000486542, PubMed 29486477

Tylleskar I, Skulberg AK, Skarra S, Nilsen T, Dale O (2018)
Pharmacodynamics and arteriovenous difference of intravenous naloxone in healthy volunteers exposed to remifentanil
Eur J Clin Pharmacol, 74 (12), 1547-1553
DOI 10.1007/s00228-018-2545-y, PubMed 30143830

Uleberg O, Pape K, Kristiansen T, Romundstad PR, Klepstad P (2018)
Population-based analysis of the impact of trauma on longer-term functional outcomes
Br J Surg (in press)
DOI 10.1002/bjs.10965, PubMed 30221344

Valdemar Duez CH, Johnsen B, Ebbesen MQ, Kvaløy MB, Grejs AM, Jeppesen AN, Søreide E, Nielsen JF, Kirkegaard H (2018)
Post resuscitation prognostication by EEG in 24 vs 48 hours of targeted temperature management
Resuscitation (in press)
DOI 10.1016/j.resuscitation.2018.10.035, PubMed 30391368

Yang R, Zhu S, Pischke SE, Haugaa H, Zou X, Tonnessen TI (2018)
Bile and circulating HMGB1 contributes to systemic inflammation in obstructive jaundice
J Surg Res, 228, 14-19
DOI 10.1016/j.jss.2018.02.049, PubMed 29907203

Zijlstra JA, Koster RW, Blom MT, Lippert FK, Svensson L, Herlitz J, Kramer-Johansen J, Ringh M, Rosenqvist M, Palsgaard Møller T, Tan HL, Beesems SG, Hulleman M, Claesson A, Folke F, Olasveengen TM, Wissenberg M, Hansen CM, Viereck S, Hollenberg J, COSTA study group (2018)
Different defibrillation strategies in survivors after out-of-hospital cardiac arrest
Heart, 104 (23), 1929-1936
DOI 10.1136/heartjnl-2017-312622, PubMed 29903805

 
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