Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Rheumatology, Dermatology and Infectious Diseases

39 publications found

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2019)
Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population
Atherosclerosis, 286, 53-59 (in press)
DOI 10.1016/j.atherosclerosis.2019.05.004, PubMed 31100620

Barth Z, Schwartz T, Flatø B, Aaløkken TM, Koller A, Lund MB, Sjaastad I, Sanner H (2019)
Association Between Nailfold Capillary Density and Pulmonary and Cardiac Involvement in Medium to Longstanding Juvenile Dermatomyositis
Arthritis Care Res (Hoboken), 71 (4), 492-497
DOI 10.1002/acr.23687, PubMed 29953739

Berge LAM, Andreassen BK, Stenehjem JS, Larsen IK, Furu K, Juzeniene A, Roscher I, Heir T, Green A, Veierød MB, Robsahm TE (2019)
Cardiovascular, antidepressant and immunosuppressive drug use in relation to risk of cutaneous melanoma: a protocol for a prospective case-control study
BMJ Open, 9 (2), e025246
DOI 10.1136/bmjopen-2018-025246, PubMed 30787091

Chen X, Aqrawi LA, Utheim TP, Tashbayev B, Utheim ØA, Reppe S, Hove LH, Herlofson BB, Singh PB, Palm Ø, Galtung HK, Jensen JCL (2019)
Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations
Sci Rep, 9 (1), 7319
DOI 10.1038/s41598-019-43714-5, PubMed 31086200

Christensen JJ, Bakke SS, Ulven SM, Retterstøl K, Henriksen T, Bollerslev J, Espevik T, Aukrust P, Halvorsen B, Holven KB (2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children
Mol Nutr Food Res, 63 (7), e1800990
DOI 10.1002/mnfr.201800990, PubMed 30702198

Christophersen A, Lund EG, Snir O, Solà E, Kanduri C, Dahal-Koirala S, Zühlke S, Molberg Ø, Utz PJ, Rohani-Pichavant M, Simard JF, Dekker CL, Lundin KEA, Sollid LM, Davis MM (2019)
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136

Consolaro A, Giancane G, Alongi A, van Dijkhuizen EHP, Aggarwal A, Al-Mayouf SM, Bovis F, De Inocencio J, Demirkaya E, Flato B, Foell D, Garay SM, Lazăr C, Lovell DJ, Montobbio C, Miettunen P, Mihaylova D, Nielsen S, Orban I, Rumba-Rozenfelde I, Magalhães CS, Shafaie N, Susic G, Trachana M, Wulffraat N et al. (2019)
Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study
Lancet Child Adolesc Health, 3 (4), 255-263
DOI 10.1016/S2352-4642(19)30027-6, PubMed 30819662

Elhai M, Boubaya M, Distler O, Smith V, Matucci-Cerinic M, Alegre Sancho JJ, Truchetet ME, Braun-Moscovici Y, Iannone F, Novikov PI, Lescoat A, Siegert E, Castellví I, Airó P, Vettori S, De Langhe E, Hachulla E, Erler A, Ananieva L, Krusche M, López-Longo FJ, Distler JHW, Hunzelmann N, Hoffmann-Vold AM, Riccieri V et al. (2019)
Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study
Ann Rheum Dis (in press)
DOI 10.1136/annrheumdis-2018-214816, PubMed 30967395

Elhai M, Hoffmann-Vold AM, Avouac J, Pezet S, Cauvet A, Leblond A, Fretheim H, Garen T, Kuwana M, Molberg Ø, Allanore Y (2019)
Performance of Candidate Serum Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease
Arthritis Rheumatol (in press)
DOI 10.1002/art.40815, PubMed 30624031

Garen T, Lerang K, Hoffmann-Vold AM, Andersson H, Midtvedt Ø, Brunborg C, Kilian K, Gudbrandsson B, Gunnarsson R, Norby G, Chaudhary A, Thoen J, Forseth KØ, Fresjar K, Førre Ø, Haugen M, Haga HJ, Gran JT, Gilboe IM, Molberg Ø, Palm Ø (2019)
Mortality and causes of death across the systemic connective tissue diseases and the primary systemic vasculitides
Rheumatology (Oxford), 58 (2), 313-320
DOI 10.1093/rheumatology/key285, PubMed 30281089

Gjersvik P (2019)
Everything is hard the first time you try
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0257, PubMed 30969037

Goll GL, Jørgensen KK, Sexton J, Olsen IC, Bolstad N, Haavardsholm EA, Lundin KEA, Tveit KS, Lorentzen M, Berset IP, Fevang BTS, Kalstad S, Ryggen K, Warren DJ, Klaasen RA, Asak Ø, Baigh S, Blomgren IM, Brenna Ø, Bruun TJ, Dvergsnes K, Frigstad SO, Hansen IM, Hatten ISH, Huppertz-Hauss G et al. (2019)
Long-term efficacy and safety of biosimilar infliximab (CT-P13) after switching from originator infliximab: open-label extension of the NOR-SWITCH trial
J Intern Med, 285 (6), 653-669
DOI 10.1111/joim.12880, PubMed 30762274

Hammenfors DS, Valim V, Bica BERG, Pasoto SG, Lilleby V, Nieto-González JC, Silva CA, Mossel E, Pereira RMR, Coelho A, Bootsma H, Thatayatikom A, Brun JG, Jonsson MV (2019)
Juvenile Sjögren's syndrome: clinical characteristics with focus on salivary gland ultrasonography
Arthritis Care Res (Hoboken) (in press)
DOI 10.1002/acr.23839, PubMed 30697959

Hesstvedt L, Gaustad P, Müller F, Torp Andersen C, Brunborg C, Mylvaganam H, Leiva RA, Erik Berdal J, Egil Ranheim T, Johnsen BO, Falch BM, Grimnes G, Skogen V, Haarr E, Sandmo Lyngøy A, Wik Larssen K, Hannula R, Åsheim Hansen B, Nordøy I, Norwegian Fungal Network (2019)
The impact of age on risk assessment, therapeutic practice and outcome in candidemia
Infect Dis (Lond), 51 (6), 425-434
DOI 10.1080/23744235.2019.1595709, PubMed 31010380

Hoel H, Ueland T, Knudsen A, Kjær A, Michelsen AE, Sagen EL, Halvorsen B, Yndestad A, Nielsen SD, Aukrust P, Lebech AM, Trøseid M (2019)
Soluble markers of IL-1 activation as predictors of first-time myocardial infarction in HIV-infected individuals
J Infect Dis (in press)
DOI 10.1093/infdis/jiz253, PubMed 31077280

Hoffmann-Vold AM, Distler O, Murray B, Kowal-Bielecka O, Khanna D, Allanore Y, EUSTAR and SCTC collaborators (2019)
Setting the international standard for longitudinal follow-up of patients with systemic sclerosis: a Delphi-based expert consensus on core clinical features
RMD Open, 5 (1), e000826
DOI 10.1136/rmdopen-2018-000826, PubMed 30997150

Holm S, Oma I, Hagve TA, Saatvedt K, Brosstad F, Mikkelsen K, Rydningen H, Risnes I, Almdahl SM, Ueland T, Aukrust P, Halvorsen B, Hollan I (2019)
Levels of Lipoprotein (a) in patients with coronary artery disease with and without inflammatory rheumatic disease: a cross-sectional study
BMJ Open, 9 (5), e030651
DOI 10.1136/bmjopen-2019-030651, PubMed 31079089

Jørgensen SF, Holm K, Macpherson ME, Storm-Larsen C, Kummen M, Fevang B, Aukrust P, Hov JR (2019)
Selective IgA deficiency in humans is associated with reduced gut microbial diversity
J Allergy Clin Immunol, 143 (5), 1969-1971.e11
DOI 10.1016/j.jaci.2019.01.019, PubMed 30707969

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167
DOI 10.1038/s41598-018-35367-7, PubMed 30655568

Kontny F, Andersen T, Ueland T, Åkerblom A, Lakic TG, Michelsen AE, Aukrust P, Bertilsson M, Becker RC, Himmelmann A, James SK, Siegbahn A, Storey RF, Wallentin L, PLATO Investigators (2019)
Pentraxin-3 vs C-reactive protein and other prognostic biomarkers in acute coronary syndrome: A substudy of the Platelet Inhibition and Patients Outcomes (PLATO) trial
Eur Heart J Acute Cardiovasc Care, 2048872619846334 (in press)
DOI 10.1177/2048872619846334, PubMed 31017470

Kvam MS, Alfonso JH, Berents TL, Randem BG, Stylianou E (2019)
Work-related hand eczema
Tidsskr Nor Laegeforen, 139 (3)
DOI 10.4045/tidsskr.18.0213, PubMed 30754949

Kvam MS, Alfonso JH, Berents TL, Randem BG, Stylianou E (2019)
Rettelse: Arbeidsrelatert håndeksem
Tidsskr Nor Laegeforen, 139 (4)
DOI 10.4045/tidsskr.19.0125, PubMed 30808096

Lillejordet E, Rashid HU, Evang JA, Taraldsrud E, Gunnarsson R (2019)
A woman in her forties with influenza symptoms and swollen arm
Tidsskr Nor Laegeforen, 139 (1)
DOI 10.4045/tidsskr.17.0170, PubMed 30644687

Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2019)
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM
Psychol Med, 1 (in press)
DOI 10.1017/S0033291719000291, PubMed 30803457

Nyakas M, Aamdal E, Jacobsen KD, Guren TK, Aamdal S, Hagene KT, Brunsvig P, Yndestad A, Halvorsen B, Tasken KA, Aukrust P, Maelandsmo GM, Ueland T (2019)
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Clin Exp Immunol (in press)
DOI 10.1111/cei.13283, PubMed 30821848

Reppe Moe SE, Molberg Ø, Strøm EH, Lerang K (2019)
Assessing the relative impact of lupus nephritis on mortality in a population-based systemic lupus erythematosus cohort
Lupus, 961203319847275 (in press)
DOI 10.1177/0961203319847275, PubMed 31072277

Risum K, Edvardsen E, Selvaag AM, Dagfinrud H, Sanner H (2019)
Measurement properties and performance of an eight-minute submaximal treadmill test in patients with juvenile idiopathic arthritis: a controlled study
Pediatr Rheumatol Online J, 17 (1), 14
DOI 10.1186/s12969-019-0316-7, PubMed 30961626

Schut C, Dalgard FJ, Halvorsen JA, Gieler U, Lien L, Aragones LT, Poot F, Jemec GBE, Misery L, Kemény L, Sampogna F, van Middendorp H, Balieva F, Linder D, Szepietowski JC, Lvov A, Marron SE, Altunay IK, Finlay AY, Salek S, Kupfer J (2019)
Occurrence, Chronicity and Intensity of Itch in a Clinical Consecutive Sample of Patients with Skin Diseases: A Multi-centre Study in 13 European Countries
Acta Derm Venereol, 99 (2), 146-151
DOI 10.2340/00015555-3040, PubMed 30226526

Siljan WW, Holter JC, Michelsen AE, Nymo SH, Lauritzen T, Oppen K, Husebye E, Ueland T, Mollnes TE, Aukrust P, Heggelund L (2019)
Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study
ERJ Open Res, 5 (1)
DOI 10.1183/23120541.00014-2019, PubMed 30863773

Singh PB, Young A, Homayouni A, Hove LH, Petrovski BÉ, Herlofson BB, Palm Ø, Rykke M, Jensen JL (2019)
Distorted Taste and Impaired Oral Health in Patients with Sicca Complaints
Nutrients, 11 (2)
DOI 10.3390/nu11020264, PubMed 30682880

Skagen K, Hetlevik SO, Zamani M, Lilleby V, Skjelland M (2019)
Preclinical Carotid Atherosclerosis in Patients With Juvenile-Onset Mixed Connective Tissue Disease
J Stroke Cerebrovasc Dis, 28 (5), 1295-1301
DOI 10.1016/j.jstrokecerebrovasdis.2019.01.027, PubMed 30772156

Solberg OG, Stavem K, Ragnarsson A, Beitnes JO, Skårdal R, Seljeflot I, Ueland T, Aukrust P, Gullestad L, Aaberge L (2019)
Index of microvascular resistance to assess the effect of rosuvastatin on microvascular function in women with chest pain and no obstructive coronary artery disease: A double-blind randomized study
Catheter Cardiovasc Interv (in press)
DOI 10.1002/ccd.28157, PubMed 30790446

Stiksrud B, Aass HCD, Lorvik KB, Ueland T, Trøseid M, Dyrhol-Riise AM (2019)
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356

Storm-Larsen C, Stiksrud B, Eriksen C, Nowak P, Holm K, Thalme A, Dyrhol-Riise AM, Brix S, Hov JR, Trøseid M (2019)
Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
AIDS, 33 (4), 645-653
DOI 10.1097/QAD.0000000000002087, PubMed 30531315

Suppa M, Gandini S, Njimi H, Bulliard JL, Correia O, Duarte AF, Peris K, Stratigos AJ, Nagore E, Longo MI, Bylaite-Bucinskiene M, Karls R, Helppikangas H, Euromelanoma Working Group,, Del Marmol V (2019)
Association of sunbed use with skin cancer risk factors in Europe: an investigation within the Euromelanoma skin cancer prevention campaign
J Eur Acad Dermatol Venereol, 33 Suppl 2, 76-88
DOI 10.1111/jdv.15307, PubMed 30811689

Trøseid M (2019)
Benmargstransplantasjon – en kur mot hiv?
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0199, PubMed 30969050

Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Løberg EM, Yndestad A, Aukrust P, Christensen G, Skjønsberg OH, Larsen KO (2019)
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936

Ueland T, Michelsen AE, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2019)
Adipokines and macrophage markers during pregnancy-Possible role for sCD163 in prediction and progression of gestational diabetes mellitus
Diabetes Metab Res Rev, 35 (3), e3114
DOI 10.1002/dmrr.3114, PubMed 30548982

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Becker RC, Bertilsson M, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Wallentin L, PLATO Investigators (2019)
Admission Levels of DKK1 (Dickkopf-1) Are Associated With Future Cardiovascular Death in Patients With Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, 39 (2), 294-302
DOI 10.1161/ATVBAHA.118.311042, PubMed 30580572

 
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