Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2015 from OUS - Department of Rheumatology, Dermatology and Infectious Diseases
83 publications found
Interleukin 23 levels are increased in carotid atherosclerosis: possible role for the interleukin 23/interleukin 17 axis
Stroke, 46 (3), 793-9
DOI 10.1161/STROKEAHA.114.006516, PubMed 25649806
Work-related skin diseases in Norway may be underreported: data from 2000 to 2013
Contact Dermatitis, 72 (6), 409-12
DOI 10.1111/cod.12355, PubMed 25693628
Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease
Rheumatology (Oxford), 54 (8), 1420-8
DOI 10.1093/rheumatology/kev004, PubMed 25740830
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426
The Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Recipients: One-Year Results of a Scandinavian Randomized Trial
Am J Transplant, 15 (7), 1967-75
DOI 10.1111/ajt.13214, PubMed 25783974
Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
PLoS One, 10 (8), e0133970
DOI 10.1371/journal.pone.0133970, PubMed 26288364
Cardiac Function in Adult Patients with Juvenile Idiopathic Arthritis
J Rheumatol, 42 (9), 1716-23
DOI 10.3899/jrheum.141351, PubMed 26178287
In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of inflammation: a cross-sectional study median 13.5 years after symptom onset
Rheumatology (Oxford), 55 (3), 535-43
DOI 10.1093/rheumatology/kev376, PubMed 26500284
Skin Barrier Function and Staphylococcus aureus Colonization in Vestibulum Nasi and Fauces in Healthy Infants and Infants with Eczema: A Population-Based Cohort Study
PLoS One, 10 (6), e0130145
DOI 10.1371/journal.pone.0130145, PubMed 26070153
Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria
J Infect Dis, 212 (11), 1835-40
DOI 10.1093/infdis/jiv283, PubMed 25980034
A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility
Am J Hum Genet, 96 (4), 565-80
DOI 10.1016/j.ajhg.2015.02.009, PubMed 25817017
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
DOI 10.1152/ajplung.00342.2014, PubMed 26071556
The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females
Genes Immun, 16 (7), 495-8
DOI 10.1038/gene.2015.32, PubMed 26291515
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Nat Commun, 6, 7146
DOI 10.1038/ncomms8146, PubMed 25994336
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715, PubMed 26461521
High Sensitivity Method to Estimate Distribution of Hyaluronan Molecular Sizes in Small Biological Samples Using Gas-Phase Electrophoretic Mobility Molecular Analysis
Int J Cell Biol, 2015, 938013
DOI 10.1155/2015/938013, PubMed 26448761
Survival and cancer risk in an unselected and complete Norwegian idiopathic inflammatory myopathy cohort
Semin Arthritis Rheum, 45 (3), 301-8
DOI 10.1016/j.semarthrit.2015.06.005, PubMed 26190563
Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox
Acta Ophthalmol, 93 (1), 59-66
DOI 10.1111/aos.12462, PubMed 25613126
Activating PI3Kδ mutations in a cohort of 669 patients with primary immunodeficiency
Clin Exp Immunol, 183 (2), 221-9
DOI 10.1111/cei.12706, PubMed 26437962
Elevated inflammatory markers in preeclamptic pregnancies, but no relation to systemic arterial stiffness
Pregnancy Hypertens, 5 (4), 325-9
DOI 10.1016/j.preghy.2015.09.003, PubMed 26597749
Altered Levels of Fatty Acids and Inflammatory and Metabolic Mediators in Epicardial Adipose Tissue in Patients With Systolic Heart Failure
J Card Fail, 21 (11), 916-23
DOI 10.1016/j.cardfail.2015.07.014, PubMed 26231517
Ichthyosis prematurity syndrome caused by a novel missense mutation in FATP4 gene-a case report from India
Clin Case Rep, 4 (1), 87-9
DOI 10.1002/ccr3.462, PubMed 26783444
A focus on inflammation as a major risk factor for atherosclerotic cardiovascular diseases
Expert Rev Cardiovasc Ther, 14 (3), 391-403
DOI 10.1586/14779072.2016.1128828, PubMed 26641944
Associations between anti-Ro52 antibodies and lung fibrosis in mixed connective tissue disease
Rheumatology (Oxford), 55 (1), 103-8
DOI 10.1093/rheumatology/kev300, PubMed 26320136
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Atherosclerosis, 243 (1), 204-10
DOI 10.1016/j.atherosclerosis.2015.09.010, PubMed 26402139
[A woman in her 60s with itching arms]
Tidsskr Nor Laegeforen, 135 (16), 1459-61
DOI 10.4045/tidsskr.15.0223, PubMed 26356457
Corynebacterium pseudotuberculosis Pneumonia in a Veterinary Student Infected During Laboratory Work
Open Forum Infect Dis, 2 (2), ofv053
DOI 10.1093/ofid/ofv053, PubMed 26380345
Vulvovaginal photodynamic therapy vs. topical corticosteroids in genital erosive lichen planus: a randomized controlled trial
Br J Dermatol, 173 (5), 1156-62
DOI 10.1111/bjd.14033, PubMed 26189484
Treatment of basal cell carcinoma in Scandinavia: evidence or eminence based?
Int J Dermatol, 54 (9), 1030-3
DOI 10.1111/ijd.12599, PubMed 25660368
Twenty-two years of candidaemia surveillance: results from a Norwegian national study
Clin Microbiol Infect, 21 (10), 938-45
DOI 10.1016/j.cmi.2015.06.008, PubMed 26093076
Predictive value of serial high-resolution computed tomography analyses and concurrent lung function tests in systemic sclerosis
Arthritis Rheumatol, 67 (8), 2205-12
DOI 10.1002/art.39166, PubMed 25916462
Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway
BMC Infect Dis, 15, 64
DOI 10.1186/s12879-015-0803-5, PubMed 25887603
[A boy with a wound on his finger that would not heal]
Tidsskr Nor Laegeforen, 135 (5), 445-8
DOI 10.4045/tidsskr.14.0759, PubMed 25761032
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis
Atherosclerosis, 241 (2), 480-94
DOI 10.1016/j.atherosclerosis.2015.05.038, PubMed 26086357
Hemophagocytic lymphohistiocytosis in leprosy
Lepr Rev, 86 (4), 403-6
PubMed 26964439
IRF4 Is a Critical Gene in Retinoic Acid-Mediated Plasma Cell Formation and Is Deregulated in Common Variable Immunodeficiency-Derived B Cells
J Immunol, 195 (6), 2601-11
DOI 10.4049/jimmunol.1500250, PubMed 26276871
A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory study
Microvasc Res, 102, 19-24
DOI 10.1016/j.mvr.2015.07.007, PubMed 26254260
A Nationwide Study of Norwegian Patients with Hereditary Angioedema with C1 Inhibitor Deficiency Identified Six Novel Mutations in SERPING1
PLoS One, 10 (7), e0131637
DOI 10.1371/journal.pone.0131637, PubMed 26154504
Disk abnormality coexists with any degree of synovial and osseous abnormality in the temporomandibular joints of children with juvenile idiopathic arthritis
Pediatr Radiol, 46 (3), 331-41
DOI 10.1007/s00247-015-3493-7, PubMed 26637998
Body mass index influence interferon-beta treatment response in multiple sclerosis
J Neuroimmunol, 288, 92-7
DOI 10.1016/j.jneuroim.2015.09.008, PubMed 26531700
Rapid Anti-Inflammatory Effects of Gonadotropin-Releasing Hormone Antagonism in Rheumatoid Arthritis Patients with High Gonadotropin Levels in the AGRA Trial
PLoS One, 10 (10), e0139439
DOI 10.1371/journal.pone.0139439, PubMed 26460564
Soluble CXCL16 and risk of myocardial infarction: The HUNT study in Norway
Atherosclerosis, 244, 188-94
DOI 10.1016/j.atherosclerosis.2015.11.022, PubMed 26649903
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma
Nat Genet, 47 (9), 987-995
DOI 10.1038/ng.3373, PubMed 26237428
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ Res, 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
Aortic Stiffness and Cardiovascular Risk in Women with Previous Gestational Diabetes Mellitus
PLoS One, 10 (8), e0136892
DOI 10.1371/journal.pone.0136892, PubMed 26309121
Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells
Nat Commun, 6, 6804
DOI 10.1038/ncomms7804, PubMed 25891430
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
Nat Med, 21 (9), 1018-27
DOI 10.1038/nm.3933, PubMed 26301688
Genetic sharing and heritability of paediatric age of onset autoimmune diseases
Nat Commun, 6, 8442
DOI 10.1038/ncomms9442, PubMed 26450413
Management of non-gonococcal urethritis
BMC Infect Dis, 15, 294
DOI 10.1186/s12879-015-1043-4, PubMed 26220178
The impact of cisplatinum-based chemotherapy on ventricular function and cardiovascular risk factors in female survivors after malignant germ cell cancer
ESC Heart Fail, 2 (3), 142-149
DOI 10.1002/ehf2.12048, PubMed 28834675
Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7
Pain, 156 (9), 1637-46
DOI 10.1097/j.pain.0000000000000229, PubMed 25993546
Maternal inheritance does not predict cholesterol levels in children with familial hypercholesterolemia
Atherosclerosis, 243 (1), 155-60
DOI 10.1016/j.atherosclerosis.2015.09.014, PubMed 26386212
Serum brain-derived neurotrophic factor levels in relation to comorbid depression and cytokine levels in Nepalese men with alcohol-use disorders
Alcohol, 49 (5), 471-8
DOI 10.1016/j.alcohol.2015.01.012, PubMed 25873205
Increased Serum Levels of the Notch Ligand DLL1 are Associated with Diastolic Dysfunction, Reduced Exercise Capacity, and Adverse Outcome in Chronic Heart Failure
J Card Fail, 22 (3), 218-23
DOI 10.1016/j.cardfail.2015.07.012, PubMed 26211721
Size of the exposed body surface area, skin erythema and body mass index predict skin production of vitamin D
J Photochem Photobiol B, 149, 224-9
DOI 10.1016/j.jphotobiol.2015.06.008, PubMed 26093795
Vitamin D production after UVB exposure - a comparison of exposed skin regions
J Photochem Photobiol B, 143, 38-43
DOI 10.1016/j.jphotobiol.2014.12.026, PubMed 25594723
Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
Clin Transl Gastroenterol, 6, e95
DOI 10.1038/ctg.2015.23, PubMed 26133108
Lower Self-Reported Quality of Life in HIV-Infected Patients on cART and With Low Comorbidity Compared With Healthy Controls
J Acquir Immune Defic Syndr, 70 (1), 16-22
DOI 10.1097/QAI.0000000000000697, PubMed 26017659
Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD
PLoS One, 10 (3), e0121622
DOI 10.1371/journal.pone.0121622, PubMed 25803709
High MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection
J Acquir Immune Defic Syndr, 69 (4), 395-402
DOI 10.1097/QAI.0000000000000617, PubMed 26115437
Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
Arthritis Res Ther, 17, 231
DOI 10.1186/s13075-015-0756-5, PubMed 26315510
Vitamin D in Norwegian renal transplant recipients: A longitudinal study with repeated measurements in winter and summer
Eur J Dermatol, 25 (3), 234-9
DOI 10.1684/ejd.2015.2524, PubMed 26412038
Cutaneous squamous cell carcinoma in Norway 1963-2011: increasing incidence and stable mortality
Cancer Med, 4 (3), 472-80
DOI 10.1002/cam4.404, PubMed 25620456
Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups
Ann Rheum Dis, 75 (8), 1558-66
DOI 10.1136/annrheumdis-2015-208119, PubMed 26362759
Prednisone versus prednisone plus ciclosporin versus prednisone plus methotrexate in new-onset juvenile dermatomyositis: a randomised trial
Lancet, 387 (10019), 671-8
DOI 10.1016/S0140-6736(15)01021-1, PubMed 26645190
Vitamin D status and effect of interferon-β1a treatment on MRI activity and serum inflammation markers in relapsing-remitting multiple sclerosis
J Neuroimmunol, 280, 21-8
DOI 10.1016/j.jneuroim.2015.02.001, PubMed 25773151
Vitamin D supplementation and systemic inflammation in relapsing-remitting multiple sclerosis
J Neurol, 262 (12), 2713-21
DOI 10.1007/s00415-015-7902-5, PubMed 26429571
NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective
Biochem Biophys Res Commun, 469 (4), 1012-20
DOI 10.1016/j.bbrc.2015.12.051, PubMed 26706279
Circulating annexin A5 predicts mortality in patients with heart failure
J Intern Med, 279 (1), 89-97
DOI 10.1111/joim.12396, PubMed 26223343
Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study
DNA Repair (Amst), 28, 21-7
DOI 10.1016/j.dnarep.2015.01.013, PubMed 25703835
Allergic diseases and the effect of inhaled epinephrine in children with acute bronchiolitis: follow-up from the randomised, controlled, double-blind, Bronchiolitis ALL trial
Lancet Respir Med, 3 (9), 702-708
DOI 10.1016/S2213-2600(15)00319-7, PubMed 26321593
Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
J Acquir Immune Defic Syndr, 70 (4), 329-37
DOI 10.1097/QAI.0000000000000784, PubMed 26258571
European EADV network on assessment of severity and burden of Pruritus (PruNet): first meeting on outcome tools
J Eur Acad Dermatol Venereol, 30 (7), 1144-7
DOI 10.1111/jdv.13296, PubMed 26370062
Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences
J Invest Dermatol, 135 (7), 1771-1780
DOI 10.1038/jid.2015.85, PubMed 25739051
Circulating levels of inflammatory cytokines and cytokine receptors in patients with ankylosing spondylitis: a cross-sectional comparative study
Scand J Rheumatol, 44 (2), 118-24
DOI 10.3109/03009742.2014.956142, PubMed 25756521
Long-term follow-up of the MAINTAIN Nephritis Trial, comparing azathioprine and mycophenolate mofetil as maintenance therapy of lupus nephritis
Ann Rheum Dis, 75 (3), 526-31
DOI 10.1136/annrheumdis-2014-206897, PubMed 25757867
Increased osteoprotegerin predicts poor virological outcome during anticytomegalovirus therapy in solid organ transplant recipients
Transplantation, 99 (1), 100-5
DOI 10.1097/TP.0000000000000227, PubMed 24983306
Positive changes in self-management and disease severity following climate therapy in people with psoriasis
Acta Derm Venereol, 95 (3), 317-21
DOI 10.2340/00015555-1939, PubMed 25110924
IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
J Infect, 70 (4), 381-91
DOI 10.1016/j.jinf.2014.12.019, PubMed 25597826
Identification of macrolide-resistant Mycoplasma genitalium using real-time PCR
J Eur Acad Dermatol Venereol, 29 (8), 1616-20
DOI 10.1111/jdv.12963, PubMed 25622510
Myocardial Function by Two-Dimensional Speckle Tracking Echocardiography and Activin A May Predict Mortality in Patients with Carcinoid Intestinal Disease
Cardiology, 132 (2), 81-90
DOI 10.1159/000431076, PubMed 26111973
The Influence of Parental Divorce on Educational Ambitions of 18/19 Year-Old Adolescents from Oslo, Norway
J Child Fam Stud, 24 (10), 2865-2873
DOI 10.1007/s10826-014-0090-6, PubMed 26379414