Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2014 from OUS - Department of Rheumatology, Dermatology and Infectious Diseases
82 publications found
Matrix metalloproteinase 7 is associated with symptomatic lesions and adverse events in patients with carotid atherosclerosis
PLoS One, 9 (1), e84935
DOI 10.1371/journal.pone.0084935, PubMed 24400123
Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes
Hypertension, 63 (4), 819-26
DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
Familial globotriaosylceramide-associated cardiomyopathy mimicking Fabry disease
Heart, 100 (22), 1793-8
DOI 10.1136/heartjnl-2014-305616, PubMed 25031264
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J Intern Med, 275 (6), 621-30
DOI 10.1111/joim.12175, PubMed 24330105
Interleukin-6 signaling, soluble glycoprotein 130, and inflammation in heart failure
Curr Heart Fail Rep, 11 (2), 146-55
DOI 10.1007/s11897-014-0185-9, PubMed 24477903
Cytokine network in scrub typhus: high levels of interleukin-8 are associated with disease severity and mortality
PLoS Negl Trop Dis, 8 (2), e2648
DOI 10.1371/journal.pntd.0002648, PubMed 24516677
Increased expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental Rickettsia conorii infection
BMC Infect Dis, 14, 70
DOI 10.1186/1471-2334-14-70, PubMed 24507453
Arterial haemodynamics and coronary artery calcification in adult patients with juvenile idiopathic arthritis
Ann Rheum Dis, 74 (8), 1515-21
DOI 10.1136/annrheumdis-2013-204804, PubMed 24695010
Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions
Int J Cancer, 136 (6), 1351-60
DOI 10.1002/ijc.29099, PubMed 25077817
Increased severity and mortality in adults co-infected with malaria and HIV in Maputo, Mozambique: a prospective cross-sectional study
PLoS One, 9 (2), e88257
DOI 10.1371/journal.pone.0088257, PubMed 24505451
Cytokine network in adults with falciparum Malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity
PLoS One, 9 (12), e114480
DOI 10.1371/journal.pone.0114480, PubMed 25503583
Dysfunctional arteriovenous anastomoses in hands of systemic sclerosis patients with digital ulcers
Clin Exp Rheumatol, 32 (6 Suppl 86), S-53-9
PubMed 24847906
Soluble ST2 reflects hemodynamic stress in non-ischemic heart failure
Int J Cardiol, 179, 378-84
DOI 10.1016/j.ijcard.2014.11.003, PubMed 25464491
The effect of rosuvastatin on inflammation, matrix turnover and left ventricular remodeling in dilated cardiomyopathy: a randomized, controlled trial
PLoS One, 9 (2), e89732
DOI 10.1371/journal.pone.0089732, PubMed 24586994
Effect of a fibromyalgia rehabilitation programme in warm versus cold climate: a randomized controlled study
J Rehabil Med, 46 (7), 676-83
DOI 10.2340/16501977-1819, PubMed 24788929
Bacteria in the adventitia of cardiovascular disease patients with and without rheumatoid arthritis
PLoS One, 9 (5), e98627
DOI 10.1371/journal.pone.0098627, PubMed 24874661
Elevated odds of metabolic syndrome in psoriasis: a population-based study of age and sex differences
Br J Dermatol, 172 (2), 419-27
DOI 10.1111/bjd.13288, PubMed 25059341
2013 European guideline on the management of lymphogranuloma venereum
J Eur Acad Dermatol Venereol, 29 (1), 1-6
DOI 10.1111/jdv.12461, PubMed 24661352
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
Schizophr Res, 161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965
Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort
Ann Rheum Dis, 74 (8), 1551-6
DOI 10.1136/annrheumdis-2013-205127, PubMed 24695011
High prevalence of inclusion body myositis in Norway; a population-based clinical epidemiology study
Eur J Neurol, 22 (4), 672-e41
DOI 10.1111/ene.12627, PubMed 25530508
Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis
J Steroid Biochem Mol Biol, 145, 113-20
DOI 10.1016/j.jsbmb.2014.10.012, PubMed 25460303
Responses in acral and non-acral skin vasomotion and temperature during lowering of ambient temperature
J Therm Biol, 45, 168-74
DOI 10.1016/j.jtherbio.2014.09.003, PubMed 25436967
Increased subclinical atherosclerosis in patients with chronic plaque psoriasis
Atherosclerosis, 237 (2), 499-503
DOI 10.1016/j.atherosclerosis.2014.10.008, PubMed 25463081
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling
PLoS One, 9 (11), e112172
DOI 10.1371/journal.pone.0112172, PubMed 25398010
The HLA profiles of mixed connective tissue disease differ distinctly from the profiles of clinically related connective tissue diseases
Rheumatology (Oxford), 54 (3), 528-35
DOI 10.1093/rheumatology/keu310, PubMed 25187641
Plasma NGAL and glomerular filtration rate in cardiac transplant recipients treated with standard or reduced calcineurin inhibitor levels
Biomark Med, 8 (2), 239-45
DOI 10.2217/bmm.13.95, PubMed 24521021
Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells
Cardiovasc Res, 102 (1), 148-56
DOI 10.1093/cvr/cvu036, PubMed 24518141
Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α
Biochem Biophys Res Commun, 450 (4), 1525-30
DOI 10.1016/j.bbrc.2014.07.036, PubMed 25035925
Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13
Atherosclerosis, 234 (2), 352-9
DOI 10.1016/j.atherosclerosis.2014.03.021, PubMed 24732574
Suicidal ideation, mental health problems, and social function in adolescents with eczema: a population-based study
J Invest Dermatol, 134 (7), 1847-1854
DOI 10.1038/jid.2014.70, PubMed 24496238
Generalized bone loss in early rheumatoid arthritis patients followed for ten years in the biologic treatment era
BMC Musculoskelet Disord, 15, 289
DOI 10.1186/1471-2474-15-289, PubMed 25182527
[A man in his 30s with urethral discharge and dysuria]
Tidsskr Nor Laegeforen, 134 (1), 48-50
DOI 10.4045/tidsskr.13.0623, PubMed 24429757
Biodistribution of protoporphyrin IX in female genital erosive lichen planus after topical application of hexaminolevulinate
Photodiagnosis Photodyn Ther, 11 (2), 113-7
DOI 10.1016/j.pdpdt.2014.01.005, PubMed 24530993
Skin Care in Organ Transplant Patients Europe meeting report from Annual Meeting, Leiden, The Netherlands, 15-18 May 2014
J Invest Dermatol, 134 (12), 2861-2863
DOI 10.1038/jid.2014.307, PubMed 25381765
Performance of the 2013 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Sclerosis (SSc) in large, well-defined cohorts of SSc and mixed connective tissue disease
J Rheumatol, 42 (1), 60-3
DOI 10.3899/jrheum.140047, PubMed 25274890
Subjects with familial hypercholesterolemia are characterized by an inflammatory phenotype despite long-term intensive cholesterol lowering treatment
Atherosclerosis, 233 (2), 561-7
DOI 10.1016/j.atherosclerosis.2014.01.022, PubMed 24530965
The effect on melanoma risk of genes previously associated with telomere length
J Natl Cancer Inst, 106 (10)
DOI 10.1093/jnci/dju267, PubMed 25231748
Extraintestinal manifestations in Crohn's disease and ulcerative colitis: results from a prospective, population-based European inception cohort
Scand J Gastroenterol, 50 (3), 300-5
DOI 10.3109/00365521.2014.991752, PubMed 25535653
Implementing best practice in psoriasis: a Nordic expert group consensus
Acta Derm Venereol, 94 (5), 547-52
DOI 10.2340/00015555-1809, PubMed 24549301
Can early skin care normalise dry skin and possibly prevent atopic eczema? A pilot study in young infants
Allergol Immunopathol (Madr), 42 (6), 539-43
DOI 10.1016/j.aller.2014.06.003, PubMed 25201763
A vital role for complement in heart disease
Mol Immunol, 61 (2), 126-34
DOI 10.1016/j.molimm.2014.06.036, PubMed 25037633
A telephone-based motivational interviewing intervention has positive effects on psoriasis severity and self-management: a randomized controlled trial
Br J Dermatol, 171 (6), 1458-69
DOI 10.1111/bjd.13363, PubMed 25143061
Mortality and years of potential life loss in systemic lupus erythematosus: a population-based cohort study
Lupus, 23 (14), 1546-52
DOI 10.1177/0961203314551083, PubMed 25209070
Overnight response to infliximab in neurosarcoidosis: a case report and review of infliximab treatment practice
Clin Neuropharmacol, 37 (5), 142-8
DOI 10.1097/WNF.0000000000000047, PubMed 25229171
Multiple distinct T-cell clones in folliculotropic mycosis fungoides
Am J Dermatopathol, 36 (12), 972-6
DOI 10.1097/DAD.0000000000000095, PubMed 25140661
[A knot on the aquarium owner's hand]
Tidsskr Nor Laegeforen, 134 (7), 715
DOI 10.4045/tidsskr.13.1425, PubMed 24721859
Influence of the IL17A locus in giant cell arteritis susceptibility
Ann Rheum Dis, 73 (9), 1742-5
DOI 10.1136/annrheumdis-2014-205261, PubMed 24919468
A candidate gene approach identifies an IL33 genetic variant as a novel genetic risk factor for GCA
PLoS One, 9 (11), e113476
DOI 10.1371/journal.pone.0113476, PubMed 25409453
[A man in his forties with swelling in both orbits]
Tidsskr Nor Laegeforen, 134 (15), 1472-6
DOI 10.4045/tidsskr.13.0115, PubMed 25138406
Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of 362 patients
Arthritis Rheumatol, 66 (11), 3160-9
DOI 10.1002/art.38802, PubMed 25077692
[Woman with recurrent uveitis and neurological symptoms]
Tidsskr Nor Laegeforen, 134 (12-13), 1245-8
DOI 10.4045/tidsskr.13.0433, PubMed 24989204
Incidence, clearance, and disease progression of genital human papillomavirus infection in heterosexual men
J Infect Dis, 210 (2), 192-9
DOI 10.1093/infdis/jiu077, PubMed 24495910
Markers of atherosclerotic development in children with familial hypercholesterolemia: a literature review
Atherosclerosis, 235 (2), 299-309
DOI 10.1016/j.atherosclerosis.2014.05.917, PubMed 24908240
High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders
CNS Neurosci Ther, 20 (10), 898-904
DOI 10.1111/cns.12303, PubMed 24995667
Toll-like receptor 9 mediated responses in cardiac fibroblasts
PLoS One, 9 (8), e104398
DOI 10.1371/journal.pone.0104398, PubMed 25126740
Toll-like receptor 9-activation during onset of myocardial ischemia does not influence infarct extension
PLoS One, 9 (8), e104407
DOI 10.1371/journal.pone.0104407, PubMed 25126943
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart
Br J Pharmacol, 171 (23), 5169-81
DOI 10.1111/bph.12647, PubMed 24547784
Increased endothelial and macrophage markers are associated with disease severity and mortality in scrub typhus
J Infect, 69 (5), 462-9
DOI 10.1016/j.jinf.2014.06.018, PubMed 24995849
Low prevalence of positive interferon-gamma tests in HIV-positive long-term immigrants in Norway
Int J Tuberc Lung Dis, 18 (2), 180-7
DOI 10.5588/ijtld.13.0276, PubMed 24429310
Increasing serum levels of vitamin A, D and E are associated with alterations of different inflammation markers in patients with multiple sclerosis
J Neuroimmunol, 271 (1-2), 60-5
DOI 10.1016/j.jneuroim.2014.03.014, PubMed 24713402
Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage
PLoS One, 9 (3), e92171
DOI 10.1371/journal.pone.0092171, PubMed 24647150
Disease activity and prognostic factors in juvenile dermatomyositis: a long-term follow-up study applying the Paediatric Rheumatology International Trials Organization criteria for inactive disease and the myositis disease activity assessment tool
Rheumatology (Oxford), 53 (9), 1578-85
DOI 10.1093/rheumatology/keu146, PubMed 24692575
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
Rheumatology (Oxford), 53 (12), 2214-22
DOI 10.1093/rheumatology/keu256, PubMed 24996906
Bradykinin analysis revived--a validated method for determination of its stable metabolite in whole blood by LC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 947-948, 139-44
DOI 10.1016/j.jchromb.2013.12.033, PubMed 24424302
Disease progression into adulthood and predictors of long-term active disease in juvenile idiopathic arthritis
Ann Rheum Dis, 75 (1), 190-5
DOI 10.1136/annrheumdis-2014-206034, PubMed 25362042
The prevalence of skin disorders in Norwegian paediatric renal transplant recipients
Acta Derm Venereol, 94 (4), 421-4
DOI 10.2340/00015555-1741, PubMed 24287733
Association between moderate to severe psoriasis and periodontitis in a Scandinavian population
BMC Oral Health, 14, 139
DOI 10.1186/1472-6831-14-139, PubMed 25427764
Efficacy of high intensity exercise on disease activity and cardiovascular risk in active axial spondyloarthritis: a randomized controlled pilot study
PLoS One, 9 (9), e108688
DOI 10.1371/journal.pone.0108688, PubMed 25268365
Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9
Clin Exp Immunol, 175 (3), 439-48
DOI 10.1111/cei.12239, PubMed 24237110
Tumescent suction curettage vs. curettage only for treatment of axillary hyperhidrosis evaluated by subjective and new objective methods
Acta Derm Venereol, 94 (2), 215-20
DOI 10.2340/00015555-1671, PubMed 24002584
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
J Intern Med, 277 (6), 717-26
DOI 10.1111/joim.12328, PubMed 25382824
The urethral smear as a tool in diagnosing adenovirus-induced urethritis
Int J STD AIDS, 25 (14), 1047-9
DOI 10.1177/0956462414531561, PubMed 24737883
Novel extracellular matrix biomarkers as predictors of adverse outcome in chronic heart failure: association between biglycan and response to statin therapy in the CORONA trial
J Card Fail, 21 (2), 153-9
DOI 10.1016/j.cardfail.2014.10.016, PubMed 25451704
Predictive value of endostatin in chronic heart failure patients with poor kidney function
Cardiology, 130 (1), 17-22
DOI 10.1159/000368220, PubMed 25428583
Inflammatory cytokines as biomarkers in heart failure
Clin Chim Acta, 443, 71-7
DOI 10.1016/j.cca.2014.09.001, PubMed 25199849
Increased serum and bone matrix levels of the secreted Wnt antagonist DKK-1 in patients with growth hormone deficiency in response to growth hormone treatment
J Clin Endocrinol Metab, 100 (2), 736-43
DOI 10.1210/jc.2014-2912, PubMed 25459913
Man with macrocephaly, learning disability and multiple basal cell carcinomas
Tidsskr Nor Laegeforen, 134 (11), 1151-4
DOI 10.4045/tidsskr.13.0894, PubMed 24939783
Clinical characteristics associated with illness perception in psoriasis
Acta Derm Venereol, 94 (3), 271-5
DOI 10.2340/00015555-1673, PubMed 24002676
Adipose tissue distribution in relation to insulin sensitivity and inflammation in Pakistani and Norwegian subjects with type 2 diabetes
Scand J Clin Lab Invest, 74 (8), 700-7
DOI 10.3109/00365513.2014.953571, PubMed 25223599
Does Parental Divorce Increase Risk Behaviors among 15/16 and 18/19 year-old Adolescents? A Study from Oslo, Norway
Clin Pract Epidemiol Ment Health, 10, 29-66
DOI 10.2174/1745017901410010059, PubMed 25006342
Exonic mutations in SCN9A (NaV1.7) are found in a minority of patients with erythromelalgia
Scand J Pain, 5 (4), 217-225
DOI 10.1016/j.sjpain.2014.09.002, PubMed 29911575