Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2019 from OUS - Department of Transplantation Medicine
113 publications found
Improved Survival in Liver Transplant Patients Receiving Prolonged-release Tacrolimus-based Immunosuppression in the European Liver Transplant Registry (ELTR): An Extension Study
Transplantation, 103 (9), 1844-1862
DOI 10.1097/TP.0000000000002700, PubMed 31343568
Implementing a tailored education programme: renal transplant recipients' experiences
J Ren Care, 45 (2), 111-119
DOI 10.1111/jorc.12273, PubMed 30920177
The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review
Obes Rev, 20 (9), 1299-1311
DOI 10.1111/obr.12869, PubMed 31232513
Sex Differences in Kidney Replacement Therapy Initiation and Maintenance
Clin J Am Soc Nephrol, 14 (11), 1616-1625
DOI 10.2215/CJN.04400419, PubMed 31649071
Asymptomatic coronary artery disease in a Norwegian cohort with type 2 diabetes: a prospective angiographic study with intravascular ultrasound evaluation
Cardiovasc Diabetol, 18 (1), 26
DOI 10.1186/s12933-019-0832-2, PubMed 30851727
Enzymatic Digestion of Hyaluronan-Based Brain Extracellular Matrix in vivo Can Induce Seizures in Neonatal Mice
Front Neurosci, 13, 1033
DOI 10.3389/fnins.2019.01033, PubMed 31632233
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737
Pathophysiology of idiopathic gastroparesis and implications for therapy
Scand J Gastroenterol, 54 (1), 8-17
DOI 10.1080/00365521.2018.1558280, PubMed 30638082
Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells
Cell Transplant, UNSP 0963689719872488
DOI 10.1177/0963689719872488, PubMed 31512504
Microbubble contrast-enhanced ultrasound in the vascular evaluation after pancreas transplantation: a single-center experience
Acta Radiol, 60 (10), 1224-1231
DOI 10.1177/0284185119828190, PubMed 30754980
Organ donation for migrants and ethnic minorities
Tidsskr Nor Laegeforen, 139 (13)
DOI 10.4045/tidsskr.19.0406, PubMed 31556540
Implications of different guidelines for surveillance after serrated polyp resection in United States of America and Europe
Endoscopy, 51 (8), 750-758
DOI 10.1055/a-0916-8598, PubMed 31195423
Cardiovascular rEmodelling in living kidNey donorS with reduced glomerular filtration rate: rationale and design of the CENS study
Blood Press
DOI 10.1080/08037051.2019.1684817, PubMed 31718316
Human concentrations of uric acid scavenges adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress
Can J Physiol Pharmacol (in press)
DOI 10.1139/cjpp-2019-0024, PubMed 31518503
Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men
Sci Rep, 9 (1), 10513
DOI 10.1038/s41598-019-46935-w, PubMed 31324844
Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report
Ther Drug Monit, 41 (3), 261-307
DOI 10.1097/FTD.0000000000000640, PubMed 31045868
Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study
BMJ, 367, l5383
DOI 10.1136/bmj.l5383, PubMed 31578177
Immunosuppression and Reproductive Health After Kidney Transplantation
Transplantation, 103 (11), e325-e333
DOI 10.1097/TP.0000000000002903, PubMed 31397802
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
J Immunol, 202 (5), 1397-1405
DOI 10.4049/jimmunol.1701703, PubMed 30692213
Prospective study of chromogranin A as a predictor of progression in patients with pancreatic, small intestinal and unknown primary neuroendocrine tumors
Neuroendocrinology (in press)
DOI 10.1159/000503833, PubMed 31578011
Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis
Sci Rep, 9 (1), 8450
DOI 10.1038/s41598-019-44762-7, PubMed 31186435
Selection criteria related to long-term survival following liver transplantation for colorectal liver metastasis
Am J Transplant
DOI 10.1111/ajt.15682, PubMed 31674105
Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases
Ann Surg (in press)
DOI 10.1097/SLA.0000000000003404, PubMed 31188200
Esophageal stenting for benign and malignant disease: European Society of Gastrointestinal Endoscopy (ESGE) Cascade Guideline
Endosc Int Open, 7 (6), E833-E836
DOI 10.1055/a-0898-3523, PubMed 31198848
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease
Mucosal Immunol (in press)
DOI 10.1038/s41385-019-0222-9, PubMed 31728027
Contraceptive Choices and Counseling in Norwegian Female Renal Transplant Recipients
Transplant Proc, 51 (2), 470-474
DOI 10.1016/j.transproceed.2019.01.068, PubMed 30879570
A multiparameter model for non-invasive detection of hypoglycemia
Physiol Meas, 40 (8), 085004
DOI 10.1088/1361-6579/ab3676, PubMed 31357185
Does the Villalta scale capture the essence of postthrombotic syndrome? A qualitative study of patient experience and expert opinion
J Thromb Haemost, 17 (10), 1707-1714
DOI 10.1111/jth.14557, PubMed 31265193
Genome-wide association study of germline variants and breast cancer-specific mortality
Br J Cancer, 120 (6), 647-657
DOI 10.1038/s41416-019-0393-x, PubMed 30787463
Quality of life from a randomized trial of laparoscopic or open liver resection for colorectal liver metastases
Br J Surg, 106 (10), 1372-1380
DOI 10.1002/bjs.11227, PubMed 31322735
Estimating the Effect of Preventive Services With Databases of Administrative Claims: Reasons to Be Concerned
Am J Epidemiol, 188 (10), 1764-1767
DOI 10.1093/aje/kwz049, PubMed 30869122
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628
DOI 10.1038/s41467-019-08489-3, PubMed 30733445
The trigger-information-response model: Exploring health literacy during the first six months following a kidney transplantation
PLoS One, 14 (10), e0223533
DOI 10.1371/journal.pone.0223533, PubMed 31609988
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
Sci Adv, 5 (8), eaaw7756
DOI 10.1126/sciadv.aaw7756, PubMed 31457091
Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System
Hepatology, 69 (5), 2120-2135
DOI 10.1002/hep.30479, PubMed 30566748
Acute poisoning related to the recreational use of prescription drugs: an observational study from Oslo, Norway
BMC Emerg Med, 19 (1), 55
DOI 10.1186/s12873-019-0271-0, PubMed 31615421
Pathogenesis, diagnosis and treatment of premalignant and malignant stages of cholangiocarcinoma in primary sclerosing cholangitis
Liver Int, 39 (12), 2230-2237
DOI 10.1111/liv.14180, PubMed 31216595
Evaluation of tools for annual capture of adherence to immunosuppressive medications after renal transplantation - a single-centre open prospective trial
Transpl Int, 32 (6), 614-625
DOI 10.1111/tri.13412, PubMed 30770608
Tacrolimus area under the concentration versus time curve monitoring, using home-based volumetric absorptive capillary microsampling
Ther Drug Monit (in press)
DOI 10.1097/FTD.0000000000000697, PubMed 31479042
Liver Transplant After Normothermic Regional Perfusion From Controlled Donors After Circulatory Death: The Norwegian Experience
Transplant Proc, 51 (2), 475-478
DOI 10.1016/j.transproceed.2019.01.066, PubMed 30879571
Efficacy and Safety of Empagliflozin in Renal Transplant Recipients With Posttransplant Diabetes Mellitus
Diabetes Care, 42 (6), 1067-1074
DOI 10.2337/dc19-0093, PubMed 30862658
Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2019
Endoscopy, 51 (8), 775-794
DOI 10.1055/a-0959-0505, PubMed 31295746
Long-term risk for kidney donors with hypertension at donation - a retrospective cohort study
Transpl Int, 32 (9), 960-964
DOI 10.1111/tri.13443, PubMed 30983060
Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
Ann Surg, 270 (2), 193-199
DOI 10.1097/SLA.0000000000003209, PubMed 30676382
First Experience With Rectus Sheath Block for Postoperative Analgesia After Pancreas Transplant: A Retrospective Observational Study
Transplant Proc, 51 (2), 479-484
DOI 10.1016/j.transproceed.2019.01.065, PubMed 30879572
Kidney transplantation: an attractive and cost-effective alternative for older patients? A cost-utility study
Clin Kidney J, 12 (6), 888-894
DOI 10.1093/ckj/sfz018, PubMed 31807304
Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline
BMJ, 367, l5515
DOI 10.1136/bmj.l5515, PubMed 31578196
Tarmkreftscreening, eller ikke?
Tidsskr Nor Laegeforen, 139 (15)
DOI 10.4045/tidsskr.19.0323, PubMed 31642636
Directly observed therapy prior to ambulatory blood pressure measurement (DOT-HTN) in uncontrolled hypertensive patients - Effect on blood pressure, safety and patient perception
Blood Press, 28 (5), 327-335
DOI 10.1080/08037051.2019.1633907, PubMed 31250668
Polyp detection rates as quality indicator in clinical versus screening colonoscopy
Endosc Int Open, 7 (2), E195-E202
DOI 10.1055/a-0796-6477, PubMed 30705953
Post-transplant diabetes mellitus in patients with solid organ transplants
Nat Rev Endocrinol, 15 (3), 172-188
DOI 10.1038/s41574-018-0137-7, PubMed 30622369
Colorectal cancer screening with faecal testing, sigmoidoscopy or colonoscopy: a systematic review and network meta-analysis
BMJ Open, 9 (10), e032773
DOI 10.1136/bmjopen-2019-032773, PubMed 31578199
Breast cancer quantitative proteome and proteogenomic landscape
Nat Commun, 10 (1), 1600
DOI 10.1038/s41467-019-09018-y, PubMed 30962452
Establishing a Core Outcome Measure for Life Participation: A Standardized Outcomes in Nephrology-kidney Transplantation Consensus Workshop Report
Transplantation, 103 (6), 1199-1205
DOI 10.1097/TP.0000000000002476, PubMed 30300284
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167
DOI 10.1038/s41598-018-35367-7, PubMed 30655568
Pancreatoduodenectomy with venous resection for ductal adenocarcinoma rarely achieves complete (R0) resection
HPB (Oxford) (in press)
DOI 10.1016/j.hpb.2019.05.005, PubMed 31186199
A Fully Automated Method for the Determination of Serum Belatacept and Its Application in a Pharmacokinetic Investigation in Renal Transplant Recipients
Ther Drug Monit, 41 (1), 11-18
DOI 10.1097/FTD.0000000000000580, PubMed 30633722
The European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report 2016: a summary
Clin Kidney J, 12 (5), 702-720
DOI 10.1093/ckj/sfz011, PubMed 31583095
The gut microbial influence on cholestatic liver disease
Liver Int, 39 (7), 1186-1196
DOI 10.1111/liv.14153, PubMed 31125502
Health literacy: a new piece of the puzzle in psoriasis care? A cross-sectional study
Br J Dermatol, 180 (6), 1506-1516
DOI 10.1111/bjd.17595, PubMed 30597532
Associations between disease education, self-management support, and health literacy in psoriasis
J Dermatolog Treat
DOI 10.1080/09546634.2019.1688233, PubMed 31692398
Beyond Survival in Solid Organ Transplantation: A Summary of Expert Presentations from the Sandoz 6th Standalone Transplantation Meeting, 2018
Transplantation, 103 (9S1 Suppl 1), S1-S13
DOI 10.1097/TP.0000000000002846, PubMed 31449167
The Effect of Marine n-3 Polyunsaturated Fatty Acids on Heart Rate Variability in Renal Transplant Recipients: A Randomized Controlled Trial
Nutrients, 11 (12)
DOI 10.3390/nu11122847, PubMed 31757095
Alterations of the bile microbiome in primary sclerosing cholangitis
Gut (in press)
DOI 10.1136/gutjnl-2019-318416, PubMed 31243055
Donation after circulatory death today: an updated overview of the European landscape
Transpl Int (in press)
DOI 10.1111/tri.13506, PubMed 31482628
The EKiTE network (epidemiology in kidney transplantation - a European validated database): an initiative epidemiological and translational European collaborative research
BMC Nephrol, 20 (1), 365
DOI 10.1186/s12882-019-1522-8, PubMed 31601177
Assessment of Bowel Inflammation and Strictures by Magnetic Resonance Enterography in Long-term Crohn's Disease
J Crohns Colitis, 13 (5), 607-614
DOI 10.1093/ecco-jcc/jjy208, PubMed 30541145
Endoscopic management of common bile duct stones: European Society of Gastrointestinal Endoscopy (ESGE) guideline
Endoscopy, 51 (5), 472-491
DOI 10.1055/a-0862-0346, PubMed 30943551
Aging-Related Expression of Twinfilin-1 Regulates Cholangiocyte Biological Response to Injury
Hepatology, 70 (3), 883-898
DOI 10.1002/hep.30466, PubMed 30561764
The Novel Oncolytic Compound LTX-401 Induces Antitumor Immune Responses in Experimental Hepatocellular Carcinoma
Mol Ther Oncolytics, 14, 139-148
DOI 10.1016/j.omto.2019.05.002, PubMed 31211244
Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
Scand J Gastroenterol, 54 (6), 690-699
DOI 10.1080/00365521.2019.1624815, PubMed 31190584
Correlation Between Baseline GFR and Subsequent Change in GFR in Norwegian Adults Without Diabetes and in Pima Indians
Am J Kidney Dis, 73 (6), 777-785
DOI 10.1053/j.ajkd.2018.11.011, PubMed 30704883
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin
Nat Immunol, 20 (12), 1644-1655
DOI 10.1038/s41590-019-0504-0, PubMed 31636468
Generiske legemidler – ikke så like som vi tror?
Tidsskr Nor Laegeforen, 139 (18)
DOI 10.4045/tidsskr.19.0740, PubMed 31823584
Normal Liver Stiffness Values in Children: A Comparison of Three Different Elastography Methods
J Pediatr Gastroenterol Nutr, 68 (5), 706-712
DOI 10.1097/MPG.0000000000002320, PubMed 30889132
Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study
Transplantation (in press)
DOI 10.1097/TP.0000000000002777, PubMed 31365472
Effect of High-Intensity Interval Training in De Novo Heart Transplant Recipients in Scandinavia
Circulation, 139 (19), 2198-2211
DOI 10.1161/CIRCULATIONAHA.118.036747, PubMed 30773030
Comparison of the associations between non-traditional and traditional indices of adiposity and cardiovascular mortality: an observational study of one million person-years of follow-up
Int J Obes (Lond), 43 (5), 1082-1092
DOI 10.1038/s41366-019-0353-9, PubMed 30926954
Improving Automatic Polyp Detection Using CNN by Exploiting Temporal Dependency in Colonoscopy Video
IEEE J Biomed Health Inform (in press)
DOI 10.1109/JBHI.2019.2907434, PubMed 30946683
Effects of Oral Anticoagulants and Aspirin on Performance of Fecal Immunochemical Tests in Colorectal Cancer Screening
Gastroenterology, 156 (6), 1642-1649.e1
DOI 10.1053/j.gastro.2019.01.040, PubMed 30689972
Matrix metalloproteinase-9 mediated shedding of syndecan-4 in glomerular endothelial cells
Microcirculation, 26 (4), e12534
DOI 10.1111/micc.12534, PubMed 30703289
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
Sci Rep, 9 (1), 10351
DOI 10.1038/s41598-019-46649-z, PubMed 31316157
Higher frequency of hospitalization but lower relative mortality for pandemic influenza in people with type 2 diabetes
J Intern Med
DOI 10.1111/joim.12984, PubMed 31587396
Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis
Aliment Pharmacol Ther, 50 (5), 580-589
DOI 10.1111/apt.15375, PubMed 31250469
Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
Eur J Clin Invest, 49 (5), e13088
DOI 10.1111/eci.13088, PubMed 30762236
Enlarged lymph nodes plus rash in a man of Mediterranean origin
Tidsskr. Nor. Laegeforen., 139 (6), 533-537
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump
Sci Signal, 12 (562)
DOI 10.1126/scisignal.aau9048, PubMed 30600262
Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence
Cancer Med, 8 (3), 1269-1278
DOI 10.1002/cam4.2006, PubMed 30714677
Hallmarks of Postoperative Liver Regeneration- An Updated Insight on the Regulatory Mechanisms
J Gastroenterol Hepatol (in press)
DOI 10.1111/jgh.14944, PubMed 31782974
Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose-a randomized controlled trial
Addiction, 114 (5), 859-867
DOI 10.1111/add.14552, PubMed 30644628
Transplant oncology: assessment of response and tolerance to systemic chemotherapy for metastatic colorectal cancer after liver transplantation - a retrospective study
Transpl Int, 32 (11), 1144-1150
DOI 10.1111/tri.13471, PubMed 31209941
Performance measures for small-bowel endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Endoscopy, 51 (6), 574-598
DOI 10.1055/a-0889-9586, PubMed 31075800
Performance measures for small-bowel endoscopy: A European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
United European Gastroenterol J, 7 (5), 614-641
DOI 10.1177/2050640619850365, PubMed 31210941
Efficacy and Tolerability of High- vs Low-Volume Split-Dose Bowel Cleansing Regimens for Colonoscopy: a Systematic Review and Meta-analysis
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2019.10.044, PubMed 31683057
International comparison of trends in patients commencing renal replacement therapy by primary renal disease
Nephrology (Carlton), 24 (10), 1064-1076
DOI 10.1111/nep.13531, PubMed 30456883
A system for students' evaluation of lectures in the medical programme in Oslo
Tidsskr Nor Laegeforen, 139 (11)
DOI 10.4045/tidsskr.19.0027, PubMed 31429231
Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis - a pilot trial
Mult Scler J Exp Transl Clin, 5 (4), 2055217319888767
DOI 10.1177/2055217319888767, PubMed 31798939
Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
AIDS, 33 (4), 645-653
DOI 10.1097/QAD.0000000000002087, PubMed 30531315
Gender differences in acute recreational drug toxicity: a case series from Oslo, Norway
BMC Emerg Med, 19 (1), 29
DOI 10.1186/s12873-019-0244-3, PubMed 31035940
Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition
Cell Host Microbe, 26 (2), 252-264.e10
DOI 10.1016/j.chom.2019.07.004, PubMed 31399369
Vitamin D as a risk factor for patient survival after kidney transplantation: A prospective observational cohort study
Clin Transplant, 33 (5), e13517
DOI 10.1111/ctr.13517, PubMed 30844090
Liver transplantation as a lifesaving procedure for posthepatectomy liver failure and iatrogenic liver injuries
Langenbecks Arch Surg, 404 (3), 301-308
DOI 10.1007/s00423-019-01780-3, PubMed 30929063
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
J Heart Lung Transplant, 38 (10), 1097-1103
DOI 10.1016/j.healun.2019.06.003, PubMed 31301965
Complexity in unclassified auto-inflammatory disease: a case report illustrating the potential for disease arising from the allelic burden of multiple variants
Pediatr Rheumatol Online J, 17 (1), 70
DOI 10.1186/s12969-019-0374-x, PubMed 31660995
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
United European Gastroenterol. J., UNSP 2050640619874173
Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue
Nat Protoc, 14 (6), 1884-1925
DOI 10.1038/s41596-019-0168-0, PubMed 31110298
Validation of diagnostic utility of fasting plasma glucose and HbA1c in stable renal transplant recipients one year after transplantation
BMC Nephrol, 20 (1), 12
DOI 10.1186/s12882-018-1171-3, PubMed 30630438
Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI
Psychoneuroendocrinology, 103, 87-95
DOI 10.1016/j.psyneuen.2019.01.001, PubMed 30659986
The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation
Front Endocrinol (Lausanne), 10, 293
DOI 10.3389/fendo.2019.00293, PubMed 31139151
Tacrolimus Can Be Reliably Measured With Volumetric Absorptive Capillary Microsampling Throughout the Dose Interval in Renal Transplant Recipients
Ther Drug Monit, 41 (5), 607-614
DOI 10.1097/FTD.0000000000000655, PubMed 31584926
Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation
Transplantation, 103 (3), 630-637
DOI 10.1097/TP.0000000000002425, PubMed 30211831
Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies
Gastroenterology (in press)
DOI 10.1053/j.gastro.2019.09.011, PubMed 31563625
Marine n-3 Polyunsaturated Fatty Acid Supplementation and Quality of Life After Kidney Transplant
Transplant Proc, 51 (2), 466-469
DOI 10.1016/j.transproceed.2019.01.067, PubMed 30879569