Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Haematology

20 publications found

Andersen MF, Holme PA, Tjønnfjord GE (2019)
Kirurgiske inngrep hos pasienter med alvorlig blødersykdom 1997–2014
Tidsskr Nor Laegeforen, 139 (8)
DOI 10.4045/tidsskr.18.0592, PubMed 31062561

Beitland S, Wimmer H, Lorentsen T, Jacobsen D, Draegni T, Brunborg C, Kløw NE, Sandset PM, Sunde K (2019)
Venous thromboembolism in the critically ill: A prospective observational study of occurrence, risk factors and outcome
Acta Anaesthesiol Scand, 63 (5), 630-638
DOI 10.1111/aas.13316, PubMed 30623406

Birgegard G, Samuelsson J, Ahlstrand E, Ejerblad E, Enevold C, Ghanima W, Hasselbalch H, Nielsen CH, Knutsen H, Pedersen OB, Sørensen A, Andreasson B (2019)
Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group
Eur J Haematol, 102 (3), 235-240
DOI 10.1111/ejh.13198, PubMed 30472746

Blakstad EW, Korpela K, Lee S, Nakstad B, Moltu SJ, Strømmen K, Rønnestad AE, Brække K, Iversen PO, de Vos WM, Drevon CA (2019)
Enhanced nutrient supply and intestinal microbiota development in very low birth weight infants
Pediatr Res (in press)
DOI 10.1038/s41390-019-0412-x, PubMed 31086354

Chellappa S, Kushekhar K, Munthe LA, Tjønnfjord GE, Aandahl EM, Okkenhaug K, Taskén K (2019)
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
J Immunol, 202 (5), 1397-1405
DOI 10.4049/jimmunol.1701703, PubMed 30692213

Curry N, Albayrak C, Escobar M, Andre Holme P, Kearney S, Klamroth R, Misgav M, Négrier C, Wheeler A, Santagostino E, Shima M, Landorph A, Tønder SM, Lentz SR (2019)
Once-weekly prophylaxis with glycoPEGylated recombinant factor VIII (N8-GP) in severe haemophilia A: Safety and efficacy results from pathfinder 2 (randomized phase III trial)
Haemophilia (in press)
DOI 10.1111/hae.13712, PubMed 30817066

El-Serafi I, Loy O, Zhao Y, Oerther S, Mattsson J (2019)
Pre-formulation investigations for establishing a protocol for treosulfan handling and activation
Pharm Dev Technol, 24 (5), 639-648
DOI 10.1080/10837450.2018.1551903, PubMed 30474459

Ifversen M, Turkiewicz D, Marquart HV, Winiarski J, Buechner J, Mellgren K, Arvidson J, Rascon J, Körgvee LT, Madsen HO, Abrahamsson J, Lund B, Jonsson OG, Heilmann C, Heyman M, Schmiegelow K, Vettenranta K (2019)
Low burden of minimal residual disease prior to transplantation in children with very high risk acute lymphoblastic leukaemia: The NOPHO ALL2008 experience
Br J Haematol, 184 (6), 982-993
DOI 10.1111/bjh.15761, PubMed 30680711

Jarvis KB, Tveiterås M, de Lange C, Ruud E (2019)
Central venous line-related thromboembolism is common in children with non-high-risk acute lymphoblastic leukaemia
Acta Paediatr, 108 (6), 1167-1168
DOI 10.1111/apa.14757, PubMed 30786076

Jønsson V, Awan H, Jones ND, Johannesen TB, Steig BÁ, Andosdottir G, Tjønnfjord GE (2019)
Inheritance of Susceptibility to Malignant Blood Disorders
Sci Rep, 9 (1), 2444
DOI 10.1038/s41598-019-38879-y, PubMed 30792429

Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M et al. (2019)
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
Nat Commun, 10 (1), 1893
DOI 10.1038/s41467-019-09671-3, PubMed 31015461

Lenartova A, Randen U, Johannesen TB, Tjønnfjord GE (2019)
Richter syndrome epidemiology in a large population based chronic lymphocytic leukemia cohort from Norway
Cancer Epidemiol, 60, 128-133
DOI 10.1016/j.canep.2019.04.002, PubMed 30986631

Ljungkvist M, Strandberg K, Berntorp E, Chaireti R, Holme PA, Larsen OH, Lassila R, Jouppila A, Szanto T, Zetterberg E (2019)
Evaluation of a standardized protocol for thrombin generation using the calibrated automated thrombogram: A Nordic study
Haemophilia, 25 (2), 334-342
DOI 10.1111/hae.13640, PubMed 30715788

Pearson ADJ, Scobie N, Norga K, Ligas F, Chiodin D, Burke A, Minard-Colin V, Adamson P, Marshall LV, Balakumaran A, Benettaib B, Bhargava P, Bollard CM, Bolotin E, Bomken S, Buechner J, Burkhardt B, Caron H, Copland C, Demolis P, Egorov A, Farhan M, Zugmaier G, Gross T, Horton-Taylor D et al. (2019)
ACCELERATE and European Medicine Agency Paediatric Strategy Forum for medicinal product development for mature B-cell malignancies in children
Eur J Cancer, 110, 74-85
DOI 10.1016/j.ejca.2019.01.013, PubMed 30772656

Richardson PG, Oriol A, Beksac M, Liberati AM, Galli M, Schjesvold F, Lindsay J, Weisel K, White D, Facon T, San Miguel J, Sunami K, O'Gorman P, Sonneveld P, Robak P, Semochkin S, Schey S, Yu X, Doerr T, Bensmaine A, Biyukov T, Peluso T, Zaki M, Anderson K, Dimopoulos M et al. (2019)
Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial
Lancet Oncol (in press)
DOI 10.1016/S1470-2045(19)30152-4, PubMed 31097405

Skretting G, Andersen E, Myklebust CF, Sandset PM, Tinholt M, Iversen N, Stavik B (2019)
Transcription factor FOXP3: A repressor of the TFPI gene?
J Cell Biochem (in press)
DOI 10.1002/jcb.28563, PubMed 30861202

Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
Aging Cell, 18 (2), e12897
DOI 10.1111/acel.12897, PubMed 30712319

Saad A, Lamb L, Wang T, Hemmer MT, Spellman S, Couriel D, Alousi A, Pidala J, Abdel-Azim H, Agrawal V, Aljurf M, Beitinjaneh AM, Bhatt VR, Buchbinder D, Byrne M, Cahn JY, Cairo M, Castillo P, Chhabra S, Diaz MA, Farhan S, Floisand Y, Frangoul HA, Gadalla SM, Gajewski J et al. (2019)
Impact of T-cell dose on the outcome of T-cell replete HLA matched allogeneic peripheral blood stem cell transplantation
Biol Blood Marrow Transplant (in press)
DOI 10.1016/j.bbmt.2019.05.007, PubMed 31085303

Torkildsen S, Gorunova L, Heim S, Tjønnfjord GE, Spetalen S, Risberg B, Tran HTT, Panagopoulos I (2019)
Molecular Genetic Characterization of Acute Myeloid Leukemia With Trisomy 4 as the Sole Chromosome Abnormality
Cancer Genomics Proteomics, 16 (3), 175-178
DOI 10.21873/cgp.20123, PubMed 31018948

Wiktor-Jedrzejczak W, Drozd-Sokolowska J, Eikema DJ, Hoek J, Potter M, Wulf G, Sellner L, Ljungman P, Chevallier P, Volin L, Koc Y, Martin S, Bunjes D, Rovira M, Itälä-Remes M, Foá R, Deconinck E, Gedde-Dahl T, Cornelissen J, Collin M, Brecht A, Patel A, de Groot M, Reményi P, Nagler A et al. (2019)
EBMT prospective observational study on allogeneic hematopoietic stem cell transplantation in T-prolymphocytic leukemia (T-PLL)
Bone Marrow Transplant (in press)
DOI 10.1038/s41409-019-0448-x, PubMed 30664723

 
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