Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

Click here to see hierarchical division and subunit overview

Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Haematology

34 publications found

Andersen MF, Holme PA, Tjønnfjord GE (2019)
Surgical procedures in patients with severe haemophilia 1997–2014
Tidsskr Nor Laegeforen, 139 (8)
DOI 10.4045/tidsskr.18.0592, PubMed 31062561

Andersen MLF, Holme PA, Tjonnfjord GE (2019)
Surgical intervention in patients with severe bleeding disorder 1997-2014
Tidsskr. Nor. Laegeforen., 139 (8), 709-712

Atukunda P, Muhoozi GKM, van den Broek TJ, Kort R, Diep LM, Kaaya AN, Iversen PO, Westerberg AC (2019)
Child development, growth and microbiota: follow-up of a randomized education trial in Uganda
J Glob Health, 9 (1), 010431
DOI 10.7189/jogh-09-010431, PubMed 31131103

Atukunda P, Muhoozi GKM, Westerberg AC, Iversen PO (2019)
Nutrition, Hygiene and Stimulation Education for Impoverished Mothers in Rural Uganda: Effect on Maternal Depression Symptoms and Their Associations to Child Development Outcomes
Nutrients, 11 (7)
DOI 10.3390/nu11071561, PubMed 31373314

Beitland S, Wimmer H, Lorentsen T, Jacobsen D, Draegni T, Brunborg C, Kløw NE, Sandset PM, Sunde K (2019)
Venous thromboembolism in the critically ill: A prospective observational study of occurrence, risk factors and outcome
Acta Anaesthesiol Scand, 63 (5), 630-638
DOI 10.1111/aas.13316, PubMed 30623406

Berentsen S, Röth A, Randen U, Jilma B, Tjønnfjord GE (2019)
Cold agglutinin disease: current challenges and future prospects
J Blood Med, 10, 93-103
DOI 10.2147/JBM.S177621, PubMed 31114413

Birgegard G, Samuelsson J, Ahlstrand E, Ejerblad E, Enevold C, Ghanima W, Hasselbalch H, Nielsen CH, Knutsen H, Pedersen OB, Sørensen A, Andreasson B (2019)
Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group
Eur J Haematol, 102 (3), 235-240
DOI 10.1111/ejh.13198, PubMed 30472746

Blakstad EW, Korpela K, Lee S, Nakstad B, Moltu SJ, Strømmen K, Rønnestad AE, Brække K, Iversen PO, de Vos WM, Drevon CA (2019)
Enhanced nutrient supply and intestinal microbiota development in very low birth weight infants
Pediatr Res, 86 (3), 323-332
DOI 10.1038/s41390-019-0412-x, PubMed 31086354

Chellappa S, Kushekhar K, Munthe LA, Tjønnfjord GE, Aandahl EM, Okkenhaug K, Taskén K (2019)
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
J Immunol, 202 (5), 1397-1405
DOI 10.4049/jimmunol.1701703, PubMed 30692213

Chowdary P, Carcao M, Holme PA, Jiménez-Yuste V, Lentz SR, Møss J, Poulsen LH, Shen C, Tosetto A, Wheeler A, Santagostino E (2019)
Fixed doses of N8-GP prophylaxis maintain moderate-to-mild factor VIII levels in the majority of patients with severe hemophilia A
Res Pract Thromb Haemost, 3 (3), 542-554
DOI 10.1002/rth2.12220, PubMed 31294338

Curry N, Albayrak C, Escobar M, Andre Holme P, Kearney S, Klamroth R, Misgav M, Négrier C, Wheeler A, Santagostino E, Shima M, Landorph A, Tønder SM, Lentz SR (2019)
Once-weekly prophylaxis with glycoPEGylated recombinant factor VIII (N8-GP) in severe haemophilia A: Safety and efficacy results from pathfinder 2 (randomized phase III trial)
Haemophilia, 25 (3), 373-381
DOI 10.1111/hae.13712, PubMed 30817066

Dahm AEA, Jacobsen EM, Wik HS, Jacobsen AF, Mollnes TE, Kanse SM, Sandset PM (2019)
Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
Thromb Haemost (in press)
DOI 10.1055/s-0039-1692426, PubMed 31254974

Eilertsen AL, Dahm AEA, Høibraaten E, Lofthus CM, Mowinckel MC, Sandset PM (2019)
Relationship between sex hormone binding globulin and blood coagulation in women on postmenopausal hormone treatment
Blood Coagul Fibrinolysis, 30 (1), 17-23
DOI 10.1097/MBC.0000000000000784, PubMed 30507711

El-Serafi I, Loy O, Zhao Y, Oerther S, Mattsson J (2019)
Pre-formulation investigations for establishing a protocol for treosulfan handling and activation
Pharm Dev Technol, 24 (5), 639-648
DOI 10.1080/10837450.2018.1551903, PubMed 30474459

Gilleece MH, Labopin M, Savani BN, Yakoub-Agha I, Socié G, Gedde-Dahl T, Blaise D, Byrne JL, Craddock C, Cornelissen JJ, Arcese W, Forcade E, Crawley C, Polge E, Mohty M, Nagler A (2019)
Allogeneic haemopoietic transplantation for acute myeloid leukaemia in second complete remission: a registry report by the Acute Leukaemia Working Party of the EBMT
Leukemia (in press)
DOI 10.1038/s41375-019-0527-4, PubMed 31363160

Hillengass J, Usmani S, Rajkumar SV, Durie BGM, Mateos MV, Lonial S, Joao C, Anderson KC, García-Sanz R, Riva E, Du J, van de Donk N, Berdeja JG, Terpos E, Zamagni E, Kyle RA, San Miguel J, Goldschmidt H, Giralt S, Kumar S, Raje N, Ludwig H, Ocio E, Schots R, Einsele H et al. (2019)
International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders
Lancet Oncol, 20 (6), e302-e312
DOI 10.1016/S1470-2045(19)30309-2, PubMed 31162104

Ifversen M, Turkiewicz D, Marquart HV, Winiarski J, Buechner J, Mellgren K, Arvidson J, Rascon J, Körgvee LT, Madsen HO, Abrahamsson J, Lund B, Jonsson OG, Heilmann C, Heyman M, Schmiegelow K, Vettenranta K (2019)
Low burden of minimal residual disease prior to transplantation in children with very high risk acute lymphoblastic leukaemia: The NOPHO ALL2008 experience
Br J Haematol, 184 (6), 982-993
DOI 10.1111/bjh.15761, PubMed 30680711

Jønsson V, Awan H, Jones ND, Johannesen TB, Steig BÁ, Andosdottir G, Tjønnfjord GE (2019)
Inheritance of Susceptibility to Malignant Blood Disorders
Sci Rep, 9 (1), 2444
DOI 10.1038/s41598-019-38879-y, PubMed 30792429

Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M et al. (2019)
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
Nat Commun, 10 (1), 1893
DOI 10.1038/s41467-019-09671-3, PubMed 31015461

Lenartova A, Randen U, Johannesen TB, Tjønnfjord GE (2019)
Richter syndrome epidemiology in a large population based chronic lymphocytic leukemia cohort from Norway
Cancer Epidemiol, 60, 128-133
DOI 10.1016/j.canep.2019.04.002, PubMed 30986631

Lien K, Johansen B, Veierød MB, Haslestad AS, Bøhn SK, Melsom MN, Kardel KR, Iversen PO (2019)
Abnormal blood lactate accumulation during repeated exercise testing in myalgic encephalomyelitis/chronic fatigue syndrome
Physiol Rep, 7 (11), e14138
DOI 10.14814/phy2.14138, PubMed 31161646

Ljungkvist M, Strandberg K, Berntorp E, Chaireti R, Holme PA, Larsen OH, Lassila R, Jouppila A, Szanto T, Zetterberg E (2019)
Evaluation of a standardized protocol for thrombin generation using the calibrated automated thrombogram: A Nordic study
Haemophilia, 25 (2), 334-342
DOI 10.1111/hae.13640, PubMed 30715788

Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
J Biol Chem, 294 (20), 8197-8217
DOI 10.1074/jbc.RA118.002829, PubMed 30926605

Mateos MV, Blacklock H, Schjesvold F, Oriol A, Simpson D, George A, Goldschmidt H, Larocca A, Chanan-Khan A, Sherbenou D, Avivi I, Benyamini N, Iida S, Matsumoto M, Suzuki K, Ribrag V, Usmani SZ, Jagannath S, Ocio EM, Rodriguez-Otero P, San Miguel J, Kher U, Farooqui M, Liao J, Marinello P et al. (2019)
Pembrolizumab plus pomalidomide and dexamethasone for patients with relapsed or refractory multiple myeloma (KEYNOTE-183): a randomised, open-label, phase 3 trial
Lancet Haematol (in press)
DOI 10.1016/S2352-3026(19)30110-3, PubMed 31327687

Pearson ADJ, Scobie N, Norga K, Ligas F, Chiodin D, Burke A, Minard-Colin V, Adamson P, Marshall LV, Balakumaran A, Benettaib B, Bhargava P, Bollard CM, Bolotin E, Bomken S, Buechner J, Burkhardt B, Caron H, Copland C, Demolis P, Egorov A, Farhan M, Zugmaier G, Gross T, Horton-Taylor D et al. (2019)
ACCELERATE and European Medicine Agency Paediatric Strategy Forum for medicinal product development for mature B-cell malignancies in children
Eur J Cancer, 110, 74-85
DOI 10.1016/j.ejca.2019.01.013, PubMed 30772656

Richardson PG, Oriol A, Beksac M, Liberati AM, Galli M, Schjesvold F, Lindsay J, Weisel K, White D, Facon T, San Miguel J, Sunami K, O'Gorman P, Sonneveld P, Robak P, Semochkin S, Schey S, Yu X, Doerr T, Bensmaine A, Biyukov T, Peluso T, Zaki M, Anderson K, Dimopoulos M et al. (2019)
Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial
Lancet Oncol, 20 (6), 781-794
DOI 10.1016/S1470-2045(19)30152-4, PubMed 31097405

Sioud M, Pettersen S, Ailte I, Fløisand Y (2019)
Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides
Cancers (Basel), 11 (8)
DOI 10.3390/cancers11081088, PubMed 31370273

Skretting G, Andersen E, Myklebust CF, Sandset PM, Tinholt M, Iversen N, Stavik B (2019)
Transcription factor FOXP3: A repressor of the TFPI gene?
J Cell Biochem, 120 (8), 12924-12936
DOI 10.1002/jcb.28563, PubMed 30861202

Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
Aging Cell, 18 (2), e12897
DOI 10.1111/acel.12897, PubMed 30712319

Saad A, Lamb L, Wang T, Hemmer MT, Spellman S, Couriel D, Alousi A, Pidala J, Abdel-Azim H, Agrawal V, Aljurf M, Beitinjaneh AM, Bhatt VR, Buchbinder D, Byrne M, Cahn JY, Cairo M, Castillo P, Chhabra S, Diaz MA, Farhan S, Floisand Y, Frangoul HA, Gadalla SM, Gajewski J et al. (2019)
Impact of T Cell Dose on Outcome of T Cell-Replete HLA-Matched Allogeneic Peripheral Blood Stem Cell Transplantation
Biol Blood Marrow Transplant (in press)
DOI 10.1016/j.bbmt.2019.05.007, PubMed 31085303

Thomas AM, Gerogianni A, McAdam MB, Fløisand Y, Lau C, Espevik T, Nilsson PH, Mollnes TE, Barratt-Due A (2019)
Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood
J Immunol (in press)
DOI 10.4049/jimmunol.1900047, PubMed 31413105

Torkildsen S, Gorunova L, Heim S, Tjønnfjord GE, Spetalen S, Risberg B, Tran HTT, Panagopoulos I (2019)
Molecular Genetic Characterization of Acute Myeloid Leukemia With Trisomy 4 as the Sole Chromosome Abnormality
Cancer Genomics Proteomics, 16 (3), 175-178
DOI 10.21873/cgp.20123, PubMed 31018948

Usmani SZ, Schjesvold F, Oriol A, Karlin L, Cavo M, Rifkin RM, Yimer HA, LeBlanc R, Takezako N, McCroskey RD, Lim ABM, Suzuki K, Kosugi H, Grigoriadis G, Avivi I, Facon T, Jagannath S, Lonial S, Ghori RU, Farooqui MZH, Marinello P, San-Miguel J, KEYNOTE-185 Investigators (2019)
Pembrolizumab plus lenalidomide and dexamethasone for patients with treatment-naive multiple myeloma (KEYNOTE-185): a randomised, open-label, phase 3 trial
Lancet Haematol (in press)
DOI 10.1016/S2352-3026(19)30109-7, PubMed 31327689

Wiktor-Jedrzejczak W, Drozd-Sokolowska J, Eikema DJ, Hoek J, Potter M, Wulf G, Sellner L, Ljungman P, Chevallier P, Volin L, Koc Y, Martin S, Bunjes D, Rovira M, Itälä-Remes M, Foá R, Deconinck E, Gedde-Dahl T, Cornelissen J, Collin M, Brecht A, Patel A, de Groot M, Reményi P, Nagler A et al. (2019)
EBMT prospective observational study on allogeneic hematopoietic stem cell transplantation in T-prolymphocytic leukemia (T-PLL)
Bone Marrow Transplant (in press)
DOI 10.1038/s41409-019-0448-x, PubMed 30664723

 
Page visits: 222189