Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2018 from OUS - Department of Haematology
47 publications found
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency
Thromb Haemost, 118 (4), 664-675
DOI 10.1055/s-0038-1637690, PubMed 29618153
A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations
Case Rep Hematol, 2018, 8187659
DOI 10.1155/2018/8187659, PubMed 30510818
Nausea and vomiting in pregnancy - association with pelvic girdle pain during pregnancy and 4-6 months post-partum
BMC Pregnancy Childbirth, 18 (1), 137
DOI 10.1186/s12884-018-1764-7, PubMed 29739355
Anti-α4β7 integrin monoclonal antibody (vedolizumab) for the treatment of steroid-resistant severe intestinal acute graft-versus-host disease
Bone Marrow Transplant, 54 (7), 987-993
DOI 10.1038/s41409-018-0364-5, PubMed 30356163
Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial
Lancet, 393 (10168), 253-264
DOI 10.1016/S0140-6736(18)33003-4, PubMed 30545780
Altered structure and function of fibrinogen after cleavage by Factor VII Activating Protease (FSAP)
Biochim Biophys Acta Mol Basis Dis, 1864 (10), 3397-3406
DOI 10.1016/j.bbadis.2018.07.030, PubMed 30076961
Safety and Effectiveness of Vedolizumab in Patients with Steroid-Refractory Gastrointestinal Acute Graft-versus-Host Disease: A Retrospective Record Review
Biol Blood Marrow Transplant, 25 (4), 720-727
DOI 10.1016/j.bbmt.2018.11.013, PubMed 30468919
Safety of D-dimer testing as a stand-alone test for the exclusion of deep vein thrombosis as compared with other strategies
J Thromb Haemost, 16 (12), 2471-2481
DOI 10.1111/jth.14314, PubMed 30303610
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422
Anxiety, depression and relationship satisfaction in the pregnancy following stillbirth and after the birth of a live-born baby: a prospective study
BMC Pregnancy Childbirth, 18 (1), 41
DOI 10.1186/s12884-018-1666-8, PubMed 29361916
Neutropenia caused by hairy cell leukemia in a patient with myelofibrosis secondary to polycythemia vera: a case report
J Med Case Rep, 12 (1), 105
DOI 10.1186/s13256-018-1663-6, PubMed 29685167
Cryopreservation of primary B cells minimally influences their signaling responses
Sci Rep, 8 (1), 17651
DOI 10.1038/s41598-018-36121-9, PubMed 30518828
Continuous infusion of simoctocog alfa in haemophilia A patients undergoing surgeries
Haemophilia, 25 (1), 54-59
DOI 10.1111/hae.13625, PubMed 30394617
Intestinal microbiota development and gestational age in preterm neonates
Sci Rep, 8 (1), 2453
DOI 10.1038/s41598-018-20827-x, PubMed 29410448
Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation
Spinal Cord, 56 (11), 1076-1083
DOI 10.1038/s41393-018-0176-x, PubMed 29985456
Effect of modified Atkins diet in adults with drug-resistant focal epilepsy: A randomized clinical trial
Epilepsia, 59 (8), 1567-1576
DOI 10.1111/epi.14457, PubMed 29901816
Genetic variation in IL28B (IFNL3) and response to interferon-alpha treatment in myeloproliferative neoplasms
Eur J Haematol, 100 (5), 419-425
DOI 10.1111/ejh.13034, PubMed 29369421
Comparable outcomes of haploidentical, 10/10 and 9/10 unrelated donor transplantation in adverse karyotype AML in first complete remission
Am J Hematol, 93 (10), 1236-1244
DOI 10.1002/ajh.25231, PubMed 30058714
Protein translation, proteolysis and autophagy in human skeletal muscle atrophy after spinal cord injury
Acta Physiol (Oxf), 223 (3), e13051
DOI 10.1111/apha.13051, PubMed 29423932
Outcome of patients with Myelofibrosis relapsing after allogeneic stem cell transplant: a retrospective study by the Chronic Malignancies Working Party of EBMT
Br J Haematol, 182 (3), 418-422
DOI 10.1111/bjh.15407, PubMed 29808926
Effects of nutrition and hygiene education on oral health and growth among toddlers in rural Uganda: follow-up of a cluster-randomised controlled trial
Trop Med Int Health, 23 (4), 391-404
DOI 10.1111/tmi.13036, PubMed 29381827
Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia
Oncotarget, 9 (10), 9273-9284
DOI 10.18632/oncotarget.23949, PubMed 29507689
Realization of the right to adequate food and the nutritional status of land evictees: a case for mothers/caregivers and their children in rural Central Uganda
BMC Int Health Hum Rights, 18 (1), 21
DOI 10.1186/s12914-018-0162-6, PubMed 29793472
Biochemical and cellular consequences of the antithrombin p.Met1? mutation identified in a severe thrombophilic family
Oncotarget, 9 (69), 33202-33214
DOI 10.18632/oncotarget.26059, PubMed 30237862
Dietary Intake, Body Composition, and Oral Health Parameters among Female Patients with Primary Sjögren's Syndrome
Nutrients, 10 (7)
DOI 10.3390/nu10070866, PubMed 29973575
Linear growth following complicated severe malnutrition: 1-year follow-up cohort of Kenyan children
Arch Dis Child, 104 (3), 229-235
DOI 10.1136/archdischild-2018-315641, PubMed 30266874
Changes in susceptibility to life-threatening infections after treatment for complicated severe malnutrition in Kenya
Am J Clin Nutr, 107 (4), 626-634
DOI 10.1093/ajcn/nqy007, PubMed 29635501
Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity
J Thromb Haemost, 16 (10), 2024-2034
DOI 10.1111/jth.14258, PubMed 30070759
RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia
PLoS One, 13 (4), e0196181
DOI 10.1371/journal.pone.0196181, PubMed 29672642
Ocular findings and ocular graft-versus-host disease after allogeneic stem cell transplantation without total body irradiation
Bone Marrow Transplant, 53 (7), 863-872
DOI 10.1038/s41409-018-0090-z, PubMed 29382955
The elevated prevalence of risk factors for chronic liver disease among ageing people with hemophilia and implications for treatment
Medicine (Baltimore), 97 (39), e12551
DOI 10.1097/MD.0000000000012551, PubMed 30278553
Chronic Myeloid Leukemia Relapsing 25 Years after Allogenic Stem Cell Transplantation
Case Rep Hematol, 2018, 2045985
DOI 10.1155/2018/2045985, PubMed 30345125
Cytokinesis arrest and multiple centrosomes in B cell chronic lymphocytic leukaemia
J Cell Mol Med, 22 (5), 2846-2855
DOI 10.1111/jcmm.13579, PubMed 29516674
Effect of exogenous estrogens and progestogens on the course of migraine during reproductive age: a consensus statement by the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESCRH)
J Headache Pain, 19 (1), 76
DOI 10.1186/s10194-018-0896-5, PubMed 30171365
Retained differentiation capacity of human skeletal muscle satellite cells from spinal cord-injured individuals
Physiol Rep, 6 (12), e13739
DOI 10.14814/phy2.13739, PubMed 29906337
The impact of rivaroxaban on primary hemostasis in patients with venous thrombosis
Platelets, 31 (1), 43-47
DOI 10.1080/09537104.2018.1557618, PubMed 30569801
Activated prothrombin complex concentrate to reverse the factor Xa inhibitor (apixaban) effect before emergency surgery: a case series
J Med Case Rep, 12 (1), 138
DOI 10.1186/s13256-018-1660-9, PubMed 29764497
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects
J Allergy Clin Immunol, 142 (6), 1932-1946
DOI 10.1016/j.jaci.2018.02.055, PubMed 29729943
Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency
Blood, 131 (12), 1301-1310
DOI 10.1182/blood-2017-09-806729, PubMed 29321155
Development of a new high-affinity human antibody with antitumor activity against solid and blood malignancies
FASEB J, 32 (9), 5063-5077
DOI 10.1096/fj.201701544R, PubMed 29913558
Effects of individualized nutrition after allogeneic hematopoietic stem cell transplantation following myeloablative conditioning; a randomized controlled trial
Clin Nutr ESPEN, 28, 59-66
DOI 10.1016/j.clnesp.2018.08.002, PubMed 30390894
Post-transcriptional, post-translational and pharmacological regulation of tissue factor pathway inhibitor
Blood Coagul Fibrinolysis, 29 (8), 668-682
DOI 10.1097/MBC.0000000000000775, PubMed 30439766
Improved outcome in patients following autologous stem cell transplantation for multiple myeloma in south eastern Norway 2001-2010: a retrospective, population based analysis
BMC Cancer, 18 (1), 801
DOI 10.1186/s12885-018-4722-x, PubMed 30089450
The impact of post-pulmonary embolism syndrome and its possible determinants
Thromb Res, 171, 84-91
DOI 10.1016/j.thromres.2018.09.048, PubMed 30267974
Subtype-specific clinical and prognostic relevance of tumor-expressed F5 and regulatory F5 variants in breast cancer: the CoCaV study
J Thromb Haemost, 16 (7), 1347-1356
DOI 10.1111/jth.14151, PubMed 29766637
NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia
Leukemia, 32 (12), 2527-2535
DOI 10.1038/s41375-018-0245-3, PubMed 30201983
Rivaroxaban versus warfarin for the prevention of post-thrombotic syndrome
Thromb Res, 163, 6-11
DOI 10.1016/j.thromres.2018.01.013, PubMed 29324334