Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2014 from OUS - Department of Haematology

36 publications found

Akkök ÇA, Bergrem A, Tangen JM (2014)
Hyperleukocytosis
Tidsskr Nor Laegeforen, 134 (14), 1365
DOI 10.4045/tidsskr.13.1559, PubMed 25096431

Ali HO, Stavik B, Dørum E, Iversen N, Sandset PM, Skretting G (2014)
Oestrogen induced downregulation of TFPI expression is mediated by ERα
Thromb Res, 134 (1), 138-43
DOI 10.1016/j.thromres.2014.04.004, PubMed 24785473

Bruserud Ø, Tvedt TH, Paulsen PQ, Ahmed AB, Gedde-Dahl T, Tjønnfjord GE, Slåstad H, Heldal D, Reikvam H (2014)
Extracorporeal photopheresis (photochemotherapy) in the treatment of acute and chronic graft versus host disease: immunological mechanisms and the results from clinical studies
Cancer Immunol Immunother, 63 (8), 757-77
DOI 10.1007/s00262-014-1578-z, PubMed 24997173

Bürgler S, Gimeno A, Parente-Ribes A, Wang D, Os A, Devereux S, Jebsen P, Bogen B, Tjønnfjord GE, Munthe LA (2014)
Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism
J Immunol, 194 (2), 827-35
DOI 10.4049/jimmunol.1401350, PubMed 25505279

Döhner H, Lübbert M, Fiedler W, Fouillard L, Haaland A, Brandwein JM, Lepretre S, Reman O, Turlure P, Ottmann OG, Müller-Tidow C, Krämer A, Raffoux E, Döhner K, Schlenk RF, Voss F, Taube T, Fritsch H, Maertens J (2014)
Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy
Blood, 124 (9), 1426-33
DOI 10.1182/blood-2014-03-560557, PubMed 25006120

Geisler CH, van T' Veer MB, Jurlander J, Walewski J, Tjønnfjord G, Itälä Remes M, Kimby E, Kozak T, Polliack A, Wu KL, Wittebol S, Abrahamse-Testroote MC, Doorduijn J, Ghidey Alemayehu W, van Oers MH (2014)
Frontline low-dose alemtuzumab with fludarabine and cyclophosphamide prolongs progression-free survival in high-risk CLL
Blood, 123 (21), 3255-62
DOI 10.1182/blood-2014-01-547737, PubMed 24735962

Haig Y, Enden T, Slagsvold CE, Sandvik L, Sandset PM, Kløw NE (2014)
Residual rates of reflux and obstruction and their correlation to post-thrombotic syndrome in a randomized study on catheter-directed thrombolysis for deep vein thrombosis
J Vasc Surg Venous Lymphat Disord, 2 (2), 123-30
DOI 10.1016/j.jvsv.2013.10.054, PubMed 26993176

Hallstensen RF, Bergseth G, Foss S, Jæger S, Gedde-Dahl T, Holt J, Christiansen D, Lau C, Brekke OL, Armstrong E, Stefanovic V, Andersen JT, Sandlie I, Mollnes TE (2014)
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn
Immunobiology, 220 (4), 452-9
DOI 10.1016/j.imbio.2014.11.003, PubMed 25468724

Hjorth-Hansen H, Stenke L, Söderlund S, Dreimane A, Ehrencrona H, Gedde-Dahl T, Gjertsen BT, Höglund M, Koskenvesa P, Lotfi K, Majeed W, Markevärn B, Ohm L, Olsson-Strömberg U, Remes K, Suominen M, Simonsson B, Porkka K, Mustjoki S, Richter J, Nordic CML Study Group (2014)
Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006)
Eur J Haematol, 94 (3), 243-50
DOI 10.1111/ejh.12423, PubMed 25082346

Husøy MA, Brinch L, Tjønnfjord GE, Gedde-Dahl T, Heldal D, Holme PA, Dybedal I, Kolstad A, Akkök ÇA, Rollag H, Gaustad P, Bergan S, Egeland T, Josefsen D, Kvalheim G, Fløisand Y (2014)
[Allogeneic stem-cell transplantation in adults 1985-2012: results and development]
Tidsskr Nor Laegeforen, 134 (16), 1569-75
DOI 10.4045/tidsskr.13.1415, PubMed 25178233

Knudsen E, Carlsen H, Bøyum A, Benestad HB, Iversen PO (2014)
No major role for the transcription factor NF-κB in bone marrow function during peritonitis in the mouse
Int J Hematol, 100 (2), 111-8
DOI 10.1007/s12185-014-1598-7, PubMed 24859830

Kostovski E, Hjeltnes N, Eriksen EF, Kolset SO, Iversen PO (2014)
Differences in bone mineral density, markers of bone turnover and extracellular matrix and daily life muscular activity among patients with recent motor-incomplete versus motor-complete spinal cord injury
Calcif Tissue Int, 96 (2), 145-54
DOI 10.1007/s00223-014-9947-3, PubMed 25539858

Kristiansen A, Brandt L, Agoritsas T, Akl EA, Berge E, Bondi J, Dahm AE, Granan LP, Halvorsen S, Holme PA, Flem Jacobsen A, Jacobsen EM, Neumann I, Sandset PM, Sætre T, Tveit A, Vartdal T, Guyatt G, Vandvik PO (2014)
Adaptation of trustworthy guidelines developed using the GRADE methodology: a novel five-step process
Chest, 146 (3), 727-734
DOI 10.1378/chest.13-2828, PubMed 25180723

Kristiansen HA, Spetalen S, Fløisand Y, Heldal D (2014)
Eltrombopag in Good's Syndrome
Case Rep Hematol, 2014, 172139
DOI 10.1155/2014/172139, PubMed 25389501

Kverneland M, Taubøll E, Selmer KK, Iversen PO, Nakken KO (2014)
Modified Atkins diet may reduce serum concentrations of antiepileptic drugs
Acta Neurol Scand, 131 (3), 187-90
DOI 10.1111/ane.12330, PubMed 25312999

Misceo D, Holmgren A, Louch WE, Holme PA, Mizobuchi M, Morales RJ, De Paula AM, Stray-Pedersen A, Lyle R, Dalhus B, Christensen G, Stormorken H, Tjønnfjord GE, Frengen E (2014)
A dominant STIM1 mutation causes Stormorken syndrome
Hum Mutat, 35 (5), 556-64
DOI 10.1002/humu.22544, PubMed 24619930

Moltu SJ, Sachse D, Blakstad EW, Strømmen K, Nakstad B, Almaas AN, Westerberg AC, Rønnestad A, Brække K, Veierød MB, Iversen PO, Rise F, Berg JP, Drevon CA (2014)
Urinary metabolite profiles in premature infants show early postnatal metabolic adaptation and maturation
Nutrients, 6 (5), 1913-30
DOI 10.3390/nu6051913, PubMed 24824288

Mundal L, Sarancic M, Ose L, Iversen PO, Borgan JK, Veierød MB, Leren TP, Retterstøl K (2014)
Mortality among patients with familial hypercholesterolemia: a registry-based study in Norway, 1992-2010
J Am Heart Assoc, 3 (6), e001236
DOI 10.1161/JAHA.114.001236, PubMed 25468658

Narverud I, Retterstøl K, Iversen PO, Halvorsen B, Ueland T, Ulven SM, Ose L, Aukrust P, Veierød MB, Holven KB (2014)
Markers of atherosclerotic development in children with familial hypercholesterolemia: a literature review
Atherosclerosis, 235 (2), 299-309
DOI 10.1016/j.atherosclerosis.2014.05.917, PubMed 24908240

Panagopoulos I, Torkildsen S, Gorunova L, Tierens A, Tjønnfjord GE, Heim S (2014)
Comparison between karyotyping-FISH-reverse transcription PCR and RNA-sequencing-fusion gene identification programs in the detection of KAT6A-CREBBP in acute myeloid leukemia
PLoS One, 9 (5), e96570
DOI 10.1371/journal.pone.0096570, PubMed 24798186

Pettersson H, Knutsen H, Holmberg E, Andréasson B (2014)
Increased incidence of another cancer in myeloproliferative neoplasms patients at the time of diagnosis
Eur J Haematol, 94 (2), 152-6
DOI 10.1111/ejh.12410, PubMed 25039361

Pitkänen H, Jouppila A, Mowinckel MC, Lemponen M, Patiwael S, Sandset PM, Lassila R, Brinkman HJ (2014)
Enhanced thrombin generation and reduced intact protein S in processed solvent detergent plasma
Thromb Res, 135 (1), 167-74
DOI 10.1016/j.thromres.2014.10.020, PubMed 25466844

Ruffini PA, Os A, Dolcetti R, Tjønnfjord GE, Munthe LA, Bogen B (2014)
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
J Transl Med, 12, 207
DOI 10.1186/1479-5876-12-207, PubMed 25059102

Samarakoon PS, Sorte HS, Kristiansen BE, Skodje T, Sheng Y, Tjønnfjord GE, Stadheim B, Stray-Pedersen A, Rødningen OK, Lyle R (2014)
Identification of copy number variants from exome sequence data
BMC Genomics, 15, 661
DOI 10.1186/1471-2164-15-661, PubMed 25102989

Subramaniam S, Thielmann I, Morowski M, Pragst I, Sandset PM, Nieswandt B, Etscheid M, Kanse SM (2014)
Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP)
Thromb Haemost, 113 (4), 870-80
DOI 10.1160/TH14-06-0519, PubMed 25427855

Taraldsrud E, Fevang B, Aukrust P, Beiske KH, Fløisand Y, Frøland S, Rollag H, Olweus J (2014)
Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9
Clin Exp Immunol, 175 (3), 439-48
DOI 10.1111/cei.12239, PubMed 24237110

Tavoly M, Jelsness-Jørgensen LP, Wik HS, Roaldsnes C, Sandset PM, Ghanima W (2014)
Quality of life after pulmonary embolism: first cross-cultural evaluation of the pulmonary embolism quality-of-life (PEmb-QoL) questionnaire in a Norwegian cohort
Qual Life Res, 24 (2), 417-25
DOI 10.1007/s11136-014-0779-4, PubMed 25120017

Tikkinen KA, Agarwal A, Craigie S, Cartwright R, Gould MK, Haukka J, Naspro R, Novara G, Sandset PM, Siemieniuk RA, Violette PD, Guyatt GH (2014)
Systematic reviews of observational studies of risk of thrombosis and bleeding in urological surgery (ROTBUS): introduction and methodology
Syst Rev, 3, 150
DOI 10.1186/2046-4053-3-150, PubMed 25540016

Tinholt M, Viken MK, Dahm AE, Vollan HK, Sahlberg KK, Garred O, Børresen-Dale AL, Jacobsen AF, Kristensen V, Bukholm I, Kåresen R, Schlichting E, Skretting G, Lie BA, Sandset PM, Iversen N (2014)
Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
BMC Cancer, 14, 845
DOI 10.1186/1471-2407-14-845, PubMed 25407022

Tobiasson M, Dybedahl I, Holm MS, Karimi M, Brandefors L, Garelius H, Grövdal M, Högh-Dufva I, Grønbæk K, Jansson M, Marcher C, Nilsson L, Kittang AO, Porwit A, Saft L, Möllgård L, Hellström-Lindberg E (2014)
Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial
Blood Cancer J, 4, e189
DOI 10.1038/bcj.2014.8, PubMed 24608733

Tran HT, Sørensen B, Bjørnsen S, Pripp AH, Tjønnfjord GE, Andre Holme P (2014)
Monitoring bypassing agent therapy - a prospective crossover study comparing thromboelastometry and thrombin generation assay
Haemophilia, 21 (2), 275-83
DOI 10.1111/hae.12570, PubMed 25521720

Tvedt TH, Holme PA, Bruserud Ø (2014)
[A man in his 80s with muscle stiffness and skin bleeding]
Tidsskr Nor Laegeforen, 134 (10), 1058-61
DOI 10.4045/tidsskr.13.0817, PubMed 24865732

Tveita AA, Schjesvold FH, Sundnes O, Haabeth OA, Haraldsen G, Bogen B (2014)
Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells
Eur J Immunol, 44 (9), 2625-37
DOI 10.1002/eji.201444659, PubMed 24846412

Vangen S, Ellingsen L, Andersgaard AB, Jacobsen AF, Lorentzen B, Nyfløt LT, Rygh AB, Skulstad SM, Tappert C, Øian P (2014)
Maternal deaths in Norway 2005-2009
Tidsskr Nor Laegeforen, 134 (8), 836-9
DOI 10.4045/tidsskr.13.0203, PubMed 24780982

Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P et al. (2014)
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
Cancer Cell, 25 (6), 794-808
DOI 10.1016/j.ccr.2014.03.036, PubMed 24835589

Zeidler C, Grote UA, Nickel A, Brand B, Carlsson G, Cortesão E, Dufour C, Duhem C, Notheis G, Papadaki HA, Tamary H, Tjønnfjord GE, Tucci F, Van Droogenbroeck J, Vermylen C, Voglova J, Xicoy B, Welte K (2014)
Outcome and management of pregnancies in severe chronic neutropenia patients by the European Branch of the Severe Chronic Neutropenia International Registry
Haematologica, 99 (8), 1395-402
DOI 10.3324/haematol.2013.099101, PubMed 24997149

 
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