Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Cardiothoracic Surgery

32 publications found

Aamodt IT, Lycholip E, Celutkiene J, von Lueder T, Atar D, Falk RS, Hellesø R, Jaarsma T, Strömberg A, Lie I (2020)
Self-Care Monitoring of Heart Failure Symptoms and Lung Impedance at Home Following Hospital Discharge: Longitudinal Study
J Med Internet Res, 22 (1), e15445
DOI 10.2196/15445, PubMed 31909717

Aamodt IT, Strömberg A, Hellesø R, Jaarsma T, Lie I (2020)
Tools to Support Self-Care Monitoring at Home: Perspectives of Patients with Heart Failure
Int J Environ Res Public Health, 17 (23)
DOI 10.3390/ijerph17238916, PubMed 33266245

Bathen T, Krohg-Sørensen K, Lidal IB (2020)
Multidisciplinary aortopathy clinics: A systematic scoping review of the literature and evaluation of patient experiences from a newly started clinic in Norway
Am J Med Genet A, 182 (11), 2552-2569
DOI 10.1002/ajmg.a.61827, PubMed 32812338

Bjørnstad JL, Khan AM, Røed-Undlien H, Bendz B, Nygård S, Hoel TN, Lingaas PS (2020)
Operative survival in patients with acute aortic disease in the era of newer oral anticoagulants
Open Heart, 7 (2)
DOI 10.1136/openhrt-2020-001278, PubMed 32675298

Brun H, Pelanis E, Wiig O, Luzon JA, Birkeland S, Kumar RP, Fretland ÅA, Suther KR, Edwin B, Elle OJ (2020)
Mixed reality - new image technology in experimental use
Tidsskr Nor Laegeforen, 140 (17)
DOI 10.4045/tidsskr.20.0498, PubMed 33231396

Chivulescu M, Krohg-Sørensen K, Scheirlynck E, Lindberg BR, Dejgaard LA, Lie ØH, Helle-Valle T, Skjølsvik ET, Estensen ME, Edvardsen T, Lingaas PS, Haugaa KH (2020)
Mitral annulus disjunction is associated with adverse outcome in Marfan and Loeys-Dietz syndromes
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa324, PubMed 33280029

Christensen AH, Nygaard S, Rolid K, Nytrøen K, Gullestad L, Fiane A, Thaulow E, Døhlen G, Saul JP, Wyller VBB (2020)
Early Signs of Sinoatrial Reinnervation in the Transplanted Heart
Transplantation (in press)
DOI 10.1097/TP.0000000000003580, PubMed 33323767

Critchley WR, Stone JP, Liao Q, Qin G, Risnes I, Trafford A, Scott H, Sjöberg T, Steen S, Fildes JE (2020)
Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation
Front Immunol, 11, 1621
DOI 10.3389/fimmu.2020.01621, PubMed 32849549

Dahle G (2020)
Current Devices in TMVI and Their Limitations: Focus on Tendyne
Front Cardiovasc Med, 7, 592909
DOI 10.3389/fcvm.2020.592909, PubMed 33425997

Danielsen SO, Moons P, Leegaard M, Solheim S, Tønnessen T, Lie I (2020)
Facilitators of and barriers to reducing thirty-day readmissions and improving patient-reported outcomes after surgical aortic valve replacement: a process evaluation of the AVRre trial
BMC Health Serv Res, 20 (1), 256
DOI 10.1186/s12913-020-05125-5, PubMed 32220252

Døving M, Christensen EE, Huse LP, Vengen Ø (2020)
A case of septic arthritis of the temporomandibular joint with necrotic peri-articular infection and Lemierre's syndrome: an unusual presentation
Oral Maxillofac Surg
DOI 10.1007/s10006-020-00921-z, PubMed 33151408

Dueland S, Syversveen T, Solheim JM, Solberg S, Grut H, Bjørnbeth BA, Hagness M, Line PD (2020)
Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases
Ann Surg, 271 (2), 212-218
DOI 10.1097/SLA.0000000000003404, PubMed 31188200

Frafjord A, Skarshaug R, Hammarström C, Stankovic B, Dorg LT, Aamodt H, Woldbaek PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2020)
Antibody combinations for optimized staining of macrophages in human lung tumours
Scand J Immunol, 92 (1), e12889
DOI 10.1111/sji.12889, PubMed 32299134

Gude E, Hoel TN, Sørensen G, Broch K, Meyer A, Fiane AE (2020)
Long-term continuous flow mechanical biventricular support: 9 years and counting
Interact Cardiovasc Thorac Surg, 30 (1), 81-84
DOI 10.1093/icvts/ivz231, PubMed 31580433

Haakensen VD, Khadse A, Sandhu V, Halvorsen AR, Solberg SK, Jørgensen LH, Brustugun OT, Kure EH, Helland Å (2020)
Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy
Int J Cancer, 147 (10), 2957-2966
DOI 10.1002/ijc.33121, PubMed 32468587

Halvorsen AR, Haugen MH, Öjlert ÅK, Lund-Iversen M, Jørgensen L, Solberg S, Mælandsmo GM, Brustugun OT, Helland Å (2020)
Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
Front Oncol, 10, 590755
DOI 10.3389/fonc.2020.590755, PubMed 33324562

Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Dunér P, Tønnessen T, Lunde IG, Sjaastad I, Brakebusch C, McCulloch AD, Gomez MF, Carlson CR, Christensen G (2020)
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J Am Heart Assoc, 9 (3), e013518
DOI 10.1161/JAHA.119.013518, PubMed 32000579

Hungerford S, Bart N, Jansz P, Kay S, Emmanuel S, Namasivayam M, Dahle G, Duncan A, Hayward C, Muller DWM (2020)
Improved right ventricular function following transapical transcatheter mitral valve implantation for severe mitral regurgitation
Int J Cardiol Heart Vasc, 32, 100687
DOI 10.1016/j.ijcha.2020.100687, PubMed 33365382

Kluge KE, Langseth MS, Opstad TB, Pettersen AÅ, Arnesen H, Tønnessen T, Seljeflot I, Helseth R (2020)
Complement Activation in Association with Markers of Neutrophil Extracellular Traps and Acute Myocardial Infarction in Stable Coronary Artery Disease
Mediators Inflamm, 2020, 5080743
DOI 10.1155/2020/5080743, PubMed 32308555

Kvernebo AK, Miyamoto T, Sporastøyl AH, Wikslund LK, Måsøy SE, Drolsum L, Moe MC, Salerud G, Fukamachi K, Kvernebo K (2020)
Quantification of ocular surface microcirculation by computer assisted video microscopy and diffuse reflectance spectroscopy
Exp Eye Res, 201, 108312
DOI 10.1016/j.exer.2020.108312, PubMed 33157128

Lindberg BR, Videm V, Dahl T, Sørensen G, Fiane AE, Thiara AS (2020)
Influence of the ECMO circuit on the concentration of nutritional supplements
Sci Rep, 10 (1), 19275
DOI 10.1038/s41598-020-76299-5, PubMed 33159150

Marasco S, Simon AR, Tsui S, Schramm R, Eifert S, Hagl CM, Paç M, Kervan Ü, Fiane AE, Wagner FM, Garbade J, Özbaran M, Hayward CS, Zimpfer D, Schmitto JD (2020)
International experience using a durable, centrifugal-flow ventricular assist device for biventricular support
J Heart Lung Transplant, 39 (12), 1372-1379
DOI 10.1016/j.healun.2020.08.006, PubMed 32917479

Mohammadzadeh N, Melleby AO, Palmero S, Sjaastad I, Chakravarti S, Engebretsen KVT, Christensen G, Lunde IG, Tønnessen T (2020)
Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload
Cardiology, 145 (3), 187-198
DOI 10.1159/000505318, PubMed 31968347

Norum IB, Edvardsen T, Ruddox V, Gunther A, Dahle G, Otterstad JE (2020)
Three-dimensional versus two-dimensional transthoracic echocardiography for left ventricular outflow tract measurements in severe aortic stenosis. A cross-sectional study using computer tomography and Haegar sizers as reference
Scand Cardiovasc J, 54 (4), 220-226
DOI 10.1080/14017431.2020.1761559, PubMed 32408833

Olsen JE, Auråen H, Durheim MT, Fiane AE, Holm AM (2020)
Predictors of long intensive care need after lung transplantation
Clin Transplant, e14152
DOI 10.1111/ctr.14152, PubMed 33185913

Pischke SE, Hødnebø S, Wester T, Haugaa H, Kvernebo K, Barratt-Due A, Tønnessen TI (2020)
Intraperitoneal microdialysis detects intestinal leakage earlier than hemodynamic surveillance and systemic inflammation in a pig model
Scand J Gastroenterol
DOI 10.1080/00365521.2020.1863459, PubMed 33356757

Schalit I, Espinoza A, Pettersen FJ, Snartland S, Ringdal ML, Hoel TN, Skulstad H, Fosse E, Fiane AE, Halvorsen PS (2020)
Detection of Thromboembolic Events and Pump Thrombosis in HeartWare HVAD Using Accelerometer in a Porcine Model
ASAIO J, 66 (1), 38-48
DOI 10.1097/MAT.0000000000000954, PubMed 30688692

Stankovic B, Aamodt H, Bjørhovde HAK, Müller E, Hammarström C, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2020)
The immune microenvironment in typical carcinoid lung tumour, a brief report of four cases
Scand J Immunol, 92 (2), e12893
DOI 10.1111/sji.12893, PubMed 32433774

Törnudd M, Ramström S, Kvitting JE, Alfredsson J, Pihl R, Berg S (2020)
Protamine stimulates platelet aggregation in vitro with activation of the fibrinogen receptor and alpha-granule release, but impairs secondary activation via ADP and thrombin receptors
Platelets
DOI 10.1080/09537104.2020.1719992, PubMed 31992110

Vanem TT, Rand-Hendriksen S, Brunborg C, Geiran OR, Røe C (2020)
Health-related quality of life in Marfan syndrome: a 10-year follow-up
Health Qual Life Outcomes, 18 (1), 376
DOI 10.1186/s12955-020-01633-4, PubMed 33256748

Yu H, Brustugun OT, Ekman S, Botling J, La Fleur L, Micke P, Solberg S, Berglund A, Rivard C, Hirsch FR (2020)
Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer
Clin Lung Cancer (in press)
DOI 10.1016/j.cllc.2020.09.018, PubMed 33214079

Zimpfer D, Fiane AE, Larbalestier R, Tsui S, Jansz P, Simon A, Schueler S, Strueber M, Schmitto JD (2020)
Long-Term Survival of Patients With Advanced Heart Failure Receiving an Left Ventricular Assist Device Intended as a Bridge to Transplantation: The Registry to Evaluate the HeartWare Left Ventricular Assist System
Circ Heart Fail, 13 (3), e006252
DOI 10.1161/CIRCHEARTFAILURE.119.006252, PubMed 32164438

 
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