Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2016 from OUS - Department of Cardiothoracic Surgery

34 publications found

Abdelnoor M, Vengen ØA, Johansen O, Sandven I, Abdelnoor AM (2016)
Latitude of the study place and age of the patient are associated with incidence of mediastinitis and microbiology in open-heart surgery: a systematic review and meta-analysis
Clin Epidemiol, 8, 151-63
DOI 10.2147/CLEP.S96107, PubMed 27330329

Bapat V, Frank D, Cocchieri R, Jagielak D, Bonaros N, Aiello M, Lapeze J, Laine M, Chocron S, Muir D, Eichinger W, Thielmann M, Labrousse L, Rein KA, Verhoye JP, Gerosa G, Baumbach H, Bramlage P, Deutsch C, Thoenes M, Romano M (2016)
Transcatheter Aortic Valve Replacement Using Transaortic Access: Experience From the Multicenter, Multinational, Prospective ROUTE Registry
JACC Cardiovasc Interv, 9 (17), 1815-22
DOI 10.1016/j.jcin.2016.06.031, PubMed 27609256

Bjørnnes AK, Parry M, Lie I, Fagerland MW, Watt-Watson J, Rustøen T, Stubhaug A, Leegaard M (2016)
Pain experiences of men and women after cardiac surgery
J Clin Nurs, 25 (19-20), 3058-68
DOI 10.1111/jocn.13329, PubMed 27301786

Bjørnnes AK, Parry M, Lie I, Fagerland MW, Watt-Watson J, Rustøen T, Stubhaug A, Leegaard M (2016)
The impact of an educational pain management booklet intervention on postoperative pain control after cardiac surgery
Eur J Cardiovasc Nurs, 16 (1), 18-27
DOI 10.1177/1474515116631680, PubMed 26846145

Bugge A, Kongerud J, Brunborg C, Solberg S, Lund MB (2016)
Gender-specific survival after surgical resection for early stage non-small cell lung cancer
Acta Oncol, 56 (3), 448-454
DOI 10.1080/0284186X.2016.1253862, PubMed 27846762

Bugge A, Lund MB, Brunborg C, Solberg S, Kongerud J (2016)
Survival After Surgical Resection for Lung Cancer in Patients With Chronic Obstructive Pulmonary Disease
Ann Thorac Surg, 101 (6), 2125-31
DOI 10.1016/j.athoracsur.2015.12.057, PubMed 27016839

Dahle G, Rein KA, Fiane AE (2016)
Edwards SAPIEN XT in Native Stenotic Mitral Valve, Open Technique on Cardiopulmonary Bypass: An Option, But Safe?
Innovations (Phila), 11 (4), 288-90
DOI 10.1097/IMI.0000000000000272, PubMed 27526344

Dhondup Y, Ueland T, Dahl CP, Askevold ET, Sandanger Ø, Fiane A, Ohm IK, Sjaastad I, Finsen AV, Wæhre A, Gullestad L, Aukrust P, Yndestad A, Vinge LE (2016)
Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure
J Card Fail, 22 (10), 823-8
DOI 10.1016/j.cardfail.2016.06.013, PubMed 27349571

Eide HA, Halvorsen AR, Bjaanæs MM, Piri H, Holm R, Solberg S, Jørgensen L, Brustugun OT, Kiserud CE, Helland Å (2016)
The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma--differences in histological subtypes
BMC Cancer, 16, 71
DOI 10.1186/s12885-016-2104-9, PubMed 26858029

Eidet J, Dahle G, Bugge JF, Bendz B, Rein KA, Aaberge L, Offstad JT, Fosse E, Aakhus S, Halvorsen PS (2016)
Long-term outcomes after transcatheter aortic valve implantation: the impact of intraoperative tissue Doppler echocardiography
Interact Cardiovasc Thorac Surg, 23 (3), 403-9
DOI 10.1093/icvts/ivw159, PubMed 27241050

Fredly S, Fugelseth D, Nygaard CS, Salerud EG, Stiris T, Kvernebo K (2016)
Noninvasive assessments of oxygen delivery from the microcirculation to skin in hypothermia-treated asphyxiated newborn infants
Pediatr Res, 79 (6), 902-6
DOI 10.1038/pr.2016.16, PubMed 26854800

Joly-Battaglini A, Hammarström C, Stankovic B, Aamodt H, Stjärne J, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2016)
Rituximab efficiently depletes B cells in lung tumors and normal lung tissue
F1000Res, 5, 38
DOI 10.12688/f1000research.7599.1, PubMed 27081474

Jortveit J, Leirgul E, Eskedal L, Greve G, Fomina T, Døhlen G, Tell GS, Birkeland S, Øyen N, Holmstrøm H (2016)
Mortality and complications in 3495 children with isolated ventricular septal defects
Arch Dis Child, 101 (9), 808-13
DOI 10.1136/archdischild-2015-310154, PubMed 27091847

Kvitting JP, Geiran OR (2016)
Karl Viktor Hall: From In Situ Vein Bypass to the Tilting Disc Heart Valve Prosthesis
Ann Thorac Surg, 102 (5), 1756-1761
DOI 10.1016/j.athoracsur.2016.03.120, PubMed 27772574

Lommerud S, Hofoss D (2016)
Leg wound infection after coronary artery bypass grafting: A natural experiment comparing use and non-use of a compression stocking
Eur J Cardiovasc Nurs, 16 (2), 136-142
DOI 10.1177/1474515116641298, PubMed 27036953

Majak P, Næss PA (2016)
Rib fractures in trauma patients: does operative fixation improve outcome?
Curr Opin Crit Care, 22 (6), 572-577
DOI 10.1097/MCC.0000000000000364, PubMed 27811559

McGowan M, Hoven AS, Lund-Iversen M, Solberg S, Helland Å, Hirsch FR, Brustugun OT (2016)
PIK3CA mutations as prognostic factor in squamous cell lung carcinoma
Lung Cancer, 103, 52-57
DOI 10.1016/j.lungcan.2016.11.018, PubMed 28024696

Melleby AO, Strand ME, Romaine A, Herum KM, Skrbic B, Dahl CP, Sjaastad I, Fiane AE, Filmus J, Christensen G, Lunde IG (2016)
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS One, 11 (10), e0165079
DOI 10.1371/journal.pone.0165079, PubMed 27768722

Mishra V, Fiane AE, Winsnes BA, Geiran O, Sørensen G, Hagen TP, Gude E (2016)
Cardiac replacement therapies: outcomes and costs for heart transplantation versus circulatory assist
Scand Cardiovasc J, 51 (1), 1-7
DOI 10.1080/14017431.2016.1196826, PubMed 27248460

Muller DWM, Farivar RS, Jansz P, Bae R, Walters D, Clarke A, Grayburn PA, Stoler RC, Dahle G, Rein KA, Shaw M, Scalia GM, Guerrero M, Pearson P, Kapadia S, Gillinov M, Pichard A, Corso P, Popma J, Chuang M, Blanke P, Leipsic J, Sorajja P, Tendyne Global Feasibility Trial Investigators (2016)
Transcatheter Mitral Valve Replacement for Patients With Symptomatic Mitral Regurgitation: A Global Feasibility Trial
J Am Coll Cardiol, 69 (4), 381-391
DOI 10.1016/j.jacc.2016.10.068, PubMed 28040318

Nygaard K, Thiara AS, Tronstad C, Ringdal MA, Fiane AE (2016)
VAVD vacuum may cause bubble transgression in membrane oxygenators
Perfusion, 31 (8), 648-652
DOI 10.1177/0267659116651345, PubMed 27226328

Opsahl EM, Brauckhoff M, Schlichting E, Helset K, Svartberg J, Brauckhoff K, Mæhle L, Engebretsen LF, Sigstad E, Grøholt KK, Akslen LA, Jørgensen LH, Varhaug JE, Bjøro T (2016)
A Nationwide Study of Multiple Endocrine Neoplasia Type 2A in Norway: Predictive and Prognostic Factors for the Clinical Course of Medullary Thyroid Carcinoma
Thyroid, 26 (9), 1225-38
DOI 10.1089/thy.2015.0673, PubMed 27400880

Paramel Varghese G, Folkersen L, Strawbridge RJ, Halvorsen B, Yndestad A, Ranheim T, Krohg-Sørensen K, Skjelland M, Espevik T, Aukrust P, Lengquist M, Hedin U, Jansson JH, Fransén K, Hansson GK, Eriksson P, Sirsjö A (2016)
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
J Am Heart Assoc, 5 (5)
DOI 10.1161/JAHA.115.003031, PubMed 27207962

Rashidi M, Esmaily S, Fiane AE, Gude E, A Tønseth K, Ueland T, Gustafsson F, Eiskjær H, Rådegran G, Dellgren G (2016)
Wound complications and surgical events in de novo heart transplant patients treated with everolimus: Post-hoc analysis of the SCHEDULE trial
Int J Cardiol, 210, 80-4
DOI 10.1016/j.ijcard.2016.02.075, PubMed 26938682

Rud AK, Boye K, Fodstad Ø, Juell S, Jørgensen LH, Solberg S, Helland Å, Brustugun OT, Mælandsmo GM (2016)
Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer
Diagn Pathol, 11 (1), 50
DOI 10.1186/s13000-016-0504-4, PubMed 27316334

Schmitto JD, Zimpfer D, Fiane AE, Larbalestier R, Tsui S, Jansz P, Simon A, Schueler S, Strueber M (2016)
Long-term support of patients receiving a left ventricular assist device for advanced heart failure: a follow-up analysis of the Registry to Evaluate the HeartWare Left Ventricular Assist System
Eur J Cardiothorac Surg, 50 (5), 834-838
DOI 10.1093/ejcts/ezw224, PubMed 27412342

Schrøder M, Melum GR, Landsverk OJ, Bujko A, Yaqub S, Gran E, Aamodt H, Bækkevold ES, Jahnsen FL, Richter L (2016)
CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits
PLoS One, 11 (6), e0157387
DOI 10.1371/journal.pone.0157387, PubMed 27311059

Skagen K, Evensen K, Scott H, Krohg-Sørensen K, Vatnehol SA, Hol PK, Skjelland M, Russell D (2016)
Semiautomated Magnetic Resonance Imaging Assessment of Carotid Plaque Lipid Content
J Stroke Cerebrovasc Dis, 25 (8), 2004-10
DOI 10.1016/j.jstrokecerebrovasdis.2016.01.043, PubMed 27234919

Skarpengland T, Dahl TB, Skjelland M, Scheffler K, de Sousa MML, Gregersen I, Kuśnierczyk A, Sharma A, Slupphaug G, Eide L, Segers FM, Skagen KR, Dahl CP, Russell D, Folkersen L, Krohg-Sørensen K, Holm S, Bjørås M, Aukrust P, Halvorsen B (2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496

Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A et al. (2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939

van Melle JP, Wolff D, Hörer J, Belli E, Meyns B, Padalino M, Lindberg H, Jacobs JP, Mattila IP, Berggren H, Berger RM, Prêtre R, Hazekamp MG, Helvind M, Nosál M, Tlaskal T, Rubay J, Lazarov S, Kadner A, Hraska V, Fragata J, Pozzi M, Sarris G, Michielon G, di Carlo D et al. (2016)
Surgical options after Fontan failure
Heart, 102 (14), 1127-33
DOI 10.1136/heartjnl-2015-309235, PubMed 27076374

Weischenfeldt J, Dubash T, Drainas AP, Mardin BR, Chen Y, Stütz AM, Waszak SM, Bosco G, Halvorsen AR, Raeder B, Efthymiopoulos T, Erkek S, Siegl C, Brenner H, Brustugun OT, Dieter SM, Northcott PA, Petersen I, Pfister SM, Schneider M, Solberg SK, Thunissen E, Weichert W, Zichner T, Thomas R et al. (2016)
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
Nat Genet, 49 (1), 65-74
DOI 10.1038/ng.3722, PubMed 27869826

Zimpfer D, Strueber M, Aigner P, Schmitto JD, Fiane AE, Larbalestier R, Tsui S, Jansz P, Simon A, Schueler S, Moscato F, Schima H (2016)
Evaluation of the HeartWare ventricular assist device Lavare cycle in a particle image velocimetry model and in clinical practice
Eur J Cardiothorac Surg, 50 (5), 839-848
DOI 10.1093/ejcts/ezw232, PubMed 27605222

Aamodt H (2016)
Transition from thoracotomy to uniportal video-assisted thoracic surgery in non-small cell lung cancer-the Oslo experience
J Vis Surg, 2, 111
DOI 10.21037/jovs.2016.06.09, PubMed 29399497

 
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