Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Institute for Surgical Research ISR

22 publications found

Abadpour S, Tyrberg B, Schive SW, Huldt CW, Gennemark P, Ryberg E, Rydén-Bergsten T, Smith DM, Korsgren O, Skrtic S, Scholz H, Winzell MS (2020)
Inhibition of the prostaglandin D2-GPR44/DP2 axis improves human islet survival and function
Diabetologia, 63 (7), 1355-1367
DOI 10.1007/s00125-020-05138-z, PubMed 32350565

Amini M, Niemi E, Hisdal J, Kalvøy H, Tronstad C, Scholz H, Rosales A, Martinsen ØG (2020)
Monitoring the quality of frozen-thawed venous segments using bioimpedance spectroscopy
Physiol Meas, 41 (4), 044008
DOI 10.1088/1361-6579/ab85b7, PubMed 32235072

Andersen ØS, Krogh MR, Boe E, Storsten P, Aalen JM, Larsen CK, Skulstad H, Odland HH, Smiseth OA, Remme EW (2020)
Left bundle branch block increases left ventricular diastolic pressure during tachycardia due to incomplete relaxation
J Appl Physiol (1985), 128 (4), 729-738
DOI 10.1152/japplphysiol.01002.2018, PubMed 31999529

Berg-Knudsen TB, Ingvaldsen CA, Mørk G, Tønseth KA (2020)
Excision of skin lesions
Tidsskr Nor Laegeforen, 140 (10)
DOI 10.4045/tidsskr.20.0060, PubMed 32602315

Bjorlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
A man in his 50s with abdominal pain, itching and weight loss
Tidsskr. Nor. Laegeforen., 140 (3), 268-272

Bjørlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
Rettelse: En mann i 50-årene med magesmerter, kløe og vekttap
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.20.0137, PubMed 32192268

Bjørlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
A man in his fifties with abdominal pain, itching and weight loss
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0390, PubMed 32105028

Duchenne J, Aalen JM, Cvijic M, Larsen CK, Galli E, Bézy S, Beela AS, Ünlü S, Pagourelias ED, Winter S, Hopp E, Kongsgård E, Donal E, Fehske W, Smiseth OA, Voigt JU (2020)
Acute redistribution of regional left ventricular work by cardiac resynchronization therapy determines long-term remodelling
Eur Heart J Cardiovasc Imaging, 21 (6), 619-628
DOI 10.1093/ehjci/jeaa003, PubMed 32031587

Kierulf-Vieira KS, Sandberg CJ, Waaler J, Lund K, Skaga E, Saberniak BM, Panagopoulos I, Brandal P, Krauss S, Langmoen IA, Vik-Mo EO (2020)
A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061630, PubMed 32575464

Kleiven Ø, Bjørkavoll-Bergseth MF, Omland T, Aakre KM, Frøysa V, Erevik CB, Greve OJ, Melberg TH, Auestad B, Skadberg Ø, Edvardsen T, Ørn S (2020)
Endurance exercise training volume is not associated with progression of coronary artery calcification
Scand J Med Sci Sports, 30 (6), 1024-1032
DOI 10.1111/sms.13643, PubMed 32100340

Kleiven Ø, Edvardsen T, Ørn S (2020)
Echocardiography in the pre-participation evaluation of asymptomatic athletes: the never-ending story
Eur J Prev Cardiol, 2047487320932269 (in press)
DOI 10.1177/2047487320932269, PubMed 32580569

Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, Prescott E, Storey RF, Deaton C, Cuisset T, Agewall S, Dickstein K, Edvardsen T, Escaned J, Gersh BJ, Svitil P, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Valgimigli M, Achenbach S, Bax JJ et al. (2020)
2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes
Eur Heart J, 41 (3), 407-477
DOI 10.1093/eurheartj/ehz425, PubMed 31504439

Larsen CK, Aalen JM, Stokke C, Fjeld JG, Kongsgaard E, Duchenne J, Degtiarova G, Gheysens O, Voigt JU, Smiseth OA, Hopp E (2020)
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur Heart J Cardiovasc Imaging, 21 (2), 143-153
DOI 10.1093/ehjci/jez231, PubMed 31599327

Legøy TA, Ghila L, Vethe H, Abadpour S, Mathisen AF, Paulo JA, Scholz H, Raeder H, Chera S (2020)
In vivo hyperglycaemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress
Acta Physiol (Oxf), 228 (4), e13433
DOI 10.1111/apha.13433, PubMed 31872528

Legøy TA, Mathisen AF, Salim Z, Vethe H, Bjørlykke Y, Abadpour S, Paulo JA, Scholz H, Ræder H, Ghila L, Chera S (2020)
In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism
Front Cell Dev Biol, 8, 109
DOI 10.3389/fcell.2020.00109, PubMed 32161757

Legøy TA, Vethe H, Abadpour S, Strand BL, Scholz H, Paulo JA, Ræder H, Ghila L, Chera S (2020)
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
Sci Rep, 10 (1), 414
DOI 10.1038/s41598-019-57305-x, PubMed 31942009

Pezel T, Coisne A, Mahmoud-Elsayed H, Mandoli GE, Elgamal SM, Podlesnikar T, Cameli M, Grapsa J, Lafitte S, Edvardsen T, Donal E, Dreyfus J (2020)
EACVI communication paper: first international young dedicated multimodal cardiovascular imaging simulation education event organized by the ESC
Eur Heart J Cardiovasc Imaging, 21 (2), 124-126
DOI 10.1093/ehjci/jez299, PubMed 31834376

Rodriguez-Palomares JF, Edvardsen T, Almeida AG, Petersen SE (2020)
EuroCMR 2019 highlights
Eur Heart J Cardiovasc Imaging, 21 (2), 127-131
DOI 10.1093/ehjci/jez307, PubMed 31821461

Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888

Smistad E, Ostvik A, Salte IM, Melichova D, Nguyen TM, Haugaa K, Brunvand H, Edvardsen T, Leclerc S, Bernard O, Grenne B, Lovstakken L (2020)
Real-time automatic ejection fraction and foreshortening detection using deep learning
IEEE Trans Ultrason Ferroelectr Freq Control (in press)
DOI 10.1109/TUFFC.2020.2981037, PubMed 32175861

Stienen S, Ferreira JP, Kobayashi M, Preud'homme G, Dobre D, Machu JL, Duarte K, Bresso E, Devignes MD, López N, Girerd N, Aakhus S, Ambrosio G, Brunner-La Rocca HP, Fontes-Carvalho R, Fraser AG, van Heerebeek L, Heymans S, de Keulenaer G, Marino P, McDonald K, Mebazaa A, Papp Z, Raddino R, Tschöpe C et al. (2020)
Enhanced clinical phenotyping by mechanistic bioprofiling in heart failure with preserved ejection fraction: insights from the MEDIA-DHF study (The Metabolic Road to Diastolic Heart Failure)
Biomarkers, 25 (2), 201-211
DOI 10.1080/1354750X.2020.1727015, PubMed 32063068

Storsten P, Aalen JM, Boe E, Remme EW, Gjesdal O, Larsen CK, Andersen ØS, Eriksen M, Kongsgaard E, Duchenne J, Voigt JU, Smiseth OA, Skulstad H (2020)
Mechanical Effects on Right Ventricular Function From Left Bundle Branch Block and Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging, 13 (7), 1475-1484
DOI 10.1016/j.jcmg.2019.11.016, PubMed 31954643

 
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