Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2018 from OUS - Institute for Surgical Research ISR

38 publications found

Abadpour S, Halvorsen B, Sahraoui A, Korsgren O, Aukrust P, Scholz H (2018)
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT
J Mol Endocrinol, 60 (3), 171-183
DOI 10.1530/JME-17-0182, PubMed 29330151

Benterud T, Manueldas S, Rivera S, Henckel E, Løberg EM, Norgren S, Baumbusch LO, Solberg R, Saugstad OD (2018)
Cerebellum Susceptibility to Neonatal Asphyxia: Possible Protective Effects of N-Acetylcysteine Amide
Dis Markers, 2018, 5046372
DOI 10.1155/2018/5046372, PubMed 29651324

Bjerring AW, Landgraff HE, Leirstein S, Aaeng A, Ansari HZ, Saberniak J, Murbræch K, Bruun H, Stokke TM, Haugaa KH, Hallén J, Edvardsen T, Sarvari SI (2018)
Morphological changes and myocardial function assessed by traditional and novel echocardiographic methods in preadolescent athlete's heart
Eur J Prev Cardiol, 25 (9), 1000-1007
DOI 10.1177/2047487318776079, PubMed 29785884

Boveda S, Lenarczyk R, Haugaa KH, Iliodromitis K, Finlay M, Lane D, Prinzen FW, Dagres N (2018)
Use of leadless pacemakers in Europe: results of the European Heart Rhythm Association survey
Europace, 20 (3), 555-559
DOI 10.1093/europace/eux381, PubMed 29360974

Danielsen TK, Manotheepan R, Sadredini M, Leren IS, Edwards AG, Vincent KP, Lehnart SE, Sejersted OM, Sjaastad I, Haugaa KH, Stokke MK (2018)
Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation
PLoS One, 13 (11), e0207100
DOI 10.1371/journal.pone.0207100, PubMed 30399185

Dejgaard LA, Haland TF, Lie OH, Ribe M, Bjune T, Leren IS, Berge KE, Edvardsen T, Haugaa KH (2018)
Vigorous exercise in patients with hypertrophic cardiomyopathy
Int J Cardiol, 250, 157-163
DOI 10.1016/j.ijcard.2017.07.015, PubMed 29169752

Dejgaard LA, Skjølsvik ET, Lie ØH, Ribe M, Stokke MK, Hegbom F, Scheirlynck ES, Gjertsen E, Andresen K, Helle-Valle TM, Hopp E, Edvardsen T, Haugaa KH (2018)
The Mitral Annulus Disjunction Arrhythmic Syndrome
J Am Coll Cardiol, 72 (14), 1600-1609
DOI 10.1016/j.jacc.2018.07.070, PubMed 30261961

Dumont KA, Kvitting JE, Karlsen JS, Remme EW, Hausken J, Lundblad R, Fiane AE, Urheim S (2018)
Validation of a Holographic Display for Quantification of Mitral Annular Dynamics by Three-Dimensional Echocardiography
J Am Soc Echocardiogr, 32 (2), 303-316.e4
DOI 10.1016/j.echo.2018.08.010, PubMed 30293779

Fayzullin A, Sandberg CJ, Spreadbury M, Saberniak BM, Grieg Z, Skaga E, Langmoen IA, Vik-Mo EO (2018)
Phenotypic and Expressional Heterogeneity in the Invasive Glioma Cells
Transl Oncol, 12 (1), 122-133
DOI 10.1016/j.tranon.2018.09.014, PubMed 30292065

Gibbs C, Thalamus J, Heldal K, Holla ØL, Haugaa KH, Hysing J (2018)
Predictors of mortality in high-risk patients with QT prolongation in a community hospital
Europace, 20 (FI1), f99-f107
DOI 10.1093/europace/eux286, PubMed 29036623

Hasselberg NE, Berge KE, Rasmussen M, Früh A, Ørstavik K, Haugaa KH (2018)
[Cardiomyopathy in hereditary muscular dystrophies]
Tidsskr Nor Laegeforen, 138 (1)
DOI 10.4045/tidsskr.16.0683, PubMed 29313627

Hasselberg NE, Haland TF, Saberniak J, Brekke PH, Berge KE, Leren TP, Edvardsen T, Haugaa KH (2018)
Lamin A/C cardiomyopathy: young onset, high penetrance, and frequent need for heart transplantation
Eur Heart J, 39 (10), 853-860
DOI 10.1093/eurheartj/ehx596, PubMed 29095976

Haugaa KH, Potpara TS, Boveda S, Deharo JC, Chen J, Dobreanu D, Fumagalli S, Lenarczyk R, Hernandez Madrid A, Larsen TB, Sciarrafia E, Taborsky M, Tilz RR, Pieragnoli P, Przybylski A, Dagres N (2018)
Patients' knowledge and attitudes regarding living with implantable electronic devices: results of a multicentre, multinational patient survey conducted by the European Heart Rhythm Association
Europace, 20 (2), 386-391
DOI 10.1093/europace/eux365, PubMed 29300970

Hjorthaug GA, Søreide E, Nordsletten L, Madsen JE, Reinholt FP, Niratisairak S, Dimmen S (2018)
Negative effect of zoledronic acid on tendon-to-bone healing
Acta Orthop, 89 (3), 360-366
DOI 10.1080/17453674.2018.1440189, PubMed 29493345

Hubert A, Le Rolle V, Leclercq C, Galli E, Samset E, Casset C, Mabo P, Hernandez A, Donal E (2018)
Estimation of myocardial work from pressure-strain loops analysis: an experimental evaluation
Eur Heart J Cardiovasc Imaging, 19 (12), 1372-1379
DOI 10.1093/ehjci/jey024, PubMed 29529181

Huun MU, Garberg H, Løberg EM, Escobar J, Martinez-Orgado J, Saugstad OD, Solberg R (2018)
DHA and therapeutic hypothermia in a short-term follow-up piglet model of hypoxia-ischemia: Effects on H+MRS biomarkers
PLoS One, 13 (8), e0201895
DOI 10.1371/journal.pone.0201895, PubMed 30086156

Huun MU, Garberg HT, Buonocore G, Longini M, Belvisi E, Bazzini F, Proietti F, Saugstad OD, Solberg R (2018)
Regional differences of hypothermia on oxidative stress following hypoxia-ischemia: a study of DHA and hypothermia on brain lipid peroxidation in newborn piglets
J Perinat Med, 47 (1), 82-89
DOI 10.1515/jpm-2017-0355, PubMed 30110254

Huun MU, Garberg HT, Escobar J, Chafer C, Vento M, Holme IM, Saugstad OD, Solberg R (2018)
DHA reduces oxidative stress following hypoxia-ischemia in newborn piglets: a study of lipid peroxidation products in urine and plasma
J Perinat Med, 46 (2), 209-217
DOI 10.1515/jpm-2016-0334, PubMed 28632497

Impieri D, Tønseth KA, Hide Ø, Brinck EL, Høgevold HE, Filip C (2018)
Impact of orthognathic surgery on velopharyngeal function by evaluating speech and cephalometric radiographs
J Plast Reconstr Aesthet Surg, 71 (12), 1786-1795
DOI 10.1016/j.bjps.2018.07.018, PubMed 30172730

Ingvaldsen CA, Tindholdt TT, Tønseth KA (2018)
DIEAP Flap Patients Equally as Satisfied with the Abdomen as Abdominoplasty Patients
Plast Reconstr Surg Glob Open, 6 (8), e1876
DOI 10.1097/GOX.0000000000001876, PubMed 30324061

Kaasbøll OJ, Gadicherla AK, Wang JH, Monsen VT, Hagelin EMV, Dong MQ, Attramadal H (2018)
Connective tissue growth factor (CCN2) is a matricellular preproprotein controlled by proteolytic activation
J Biol Chem, 293 (46), 17953-17970
DOI 10.1074/jbc.RA118.004559, PubMed 30262666

Lenarczyk R, Boveda S, Haugaa KH, Potpara TS, Syska P, Jedrzejczyk-Patej E, Chauvin M, Sadoul N, Dagres N (2018)
Peri-procedural routines, implantation techniques, and procedure-related complications in patients undergoing implantation of subcutaneous or transvenous automatic cardioverter-defibrillators: results of the European Snapshot Survey on S-ICD Implantation (ESSS-SICDI)
Europace, 20 (7), 1218-1224
DOI 10.1093/europace/euy092, PubMed 29762683

Linde C, Bongiorni MG, Birgersdotter-Green U, Curtis AB, Deisenhofer I, Furokawa T, Gillis AM, Haugaa KH, Lip GYH, Van Gelder I, Malik M, Poole J, Potpara T, Savelieva I, Sarkozy A, ESC Scientific Document Group (2018)
Sex differences in cardiac arrhythmia: a consensus document of the European Heart Rhythm Association, endorsed by the Heart Rhythm Society and Asia Pacific Heart Rhythm Society
Europace, 20 (10), 1565-1565ao
DOI 10.1093/europace/euy067, PubMed 29961863

Mughal AA, Zhang L, Fayzullin A, Server A, Li Y, Wu Y, Glass R, Meling T, Langmoen IA, Leergaard TB, Vik-Mo EO (2018)
Patterns of Invasive Growth in Malignant Gliomas-The Hippocampus Emerges as an Invasion-Spared Brain Region
Neoplasia, 20 (7), 643-656
DOI 10.1016/j.neo.2018.04.001, PubMed 29793116

Reppe S, Jackson CJ, Ringstad H, Tønseth KA, Bakke H, Eidet JR, Utheim TP (2018)
High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets
Stem Cells Int, 2018, 6545876
DOI 10.1155/2018/6545876, PubMed 30581473

Schuetz C, Anazawa T, Cross SE, Labriola L, Meier RPH, Redfield RR, Scholz H, Stock PG, Zammit NW, IPITA YIC Young Investigator Committee (2018)
β Cell Replacement Therapy: The Next 10 Years
Transplantation, 102 (2), 215-229
DOI 10.1097/TP.0000000000001937, PubMed 28885496

Shegarfi H, Kane KP, Nestvold J (2018)
Listeria monocytogenes infection enhances the interaction between rat non-classical MHC-Ib molecule and Ly49 receptors
Innate Immun, 24 (4), 252-261
DOI 10.1177/1753425918759589, PubMed 29792127

Shegarfi H, Rolstad B, Kane KP, Nestvold J (2018)
Listeria monocytogenes infection differentially affects expression of ligands for NK cells and NK cell responses, depending on the cell type infected
J Leukoc Biol, 103 (3), 591-599
DOI 10.1189/jlb.2A1115-506RR, PubMed 27106671

Skottvoll FS, Berg HE, Bjørseth K, Lund K, Roos N, Bekhradnia S, Thiede B, Sandberg C, Vik-Mo EO, Roberg-Larsen H, Nyström B, Lundanes E, Wilson SR (2018)
Ultracentrifugation versus kit exosome isolation: nanoLC-MS and other tools reveal similar performance biomarkers, but also contaminations
Future Sci OA, 5 (1), FSO359
DOI 10.4155/fsoa-2018-0088, PubMed 30652024

Smiseth OA, Aalen JM (2018)
Mechanism of harm from left bundle branch block
Trends Cardiovasc Med (in press)
DOI 10.1016/j.tcm.2018.10.012, PubMed 30401603

Sokolova M, Sahraoui A, Høyem M, Øgaard J, Lien E, Aukrust P, Yndestad A, Ranheim T, Scholz H (2018)
NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction
Am J Physiol Endocrinol Metab, 315 (5), E912-E923
DOI 10.1152/ajpendo.00461.2017, PubMed 30016155

Stensrud MJ, Aalen JM, Aalen OO, Valberg M (2018)
Limitations of hazard ratios in clinical trials
Eur Heart J (in press)
DOI 10.1093/eurheartj/ehy770, PubMed 30500891

Storsten P, Eriksen M, Remme EW, Boe E, Erikssen G, Smiseth OA, Skulstad H (2018)
Dysfunction of the systemic right ventricle after atrial switch: physiological implications of altered septal geometry and load
J Appl Physiol (1985), 125 (5), 1482-1489
DOI 10.1152/japplphysiol.00255.2018, PubMed 30188795

Strand-Amundsen RJ, Reims HM, Reinholt FP, Ruud TE, Yang R, Høgetveit JO, Tønnessen TI (2018)
Ischemia/reperfusion injury in porcine intestine - Viability assessment
World J Gastroenterol, 24 (18), 2009-2023
DOI 10.3748/wjg.v24.i18.2009, PubMed 29760544

Strand-Amundsen RJ, Tronstad C, Kalvøy H, Ruud TE, Høgetveit JO, Martinsen ØG, Tønnessen TI (2018)
Small intestinal ischemia and reperfusion-bioimpedance measurements
Physiol Meas, 39 (2), 025001
DOI 10.1088/1361-6579/aaa576, PubMed 29303488

Thomas AM, Schjalm C, Nilsson PH, Lindenskov PHH, Rørtveit R, Solberg R, Saugstad OD, Berglund MM, Strömberg P, Lau C, Espevik T, Jansen JH, Castellheim A, Mollnes TE, Barratt-Due A (2018)
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome
Neonatology, 113 (4), 322-330
DOI 10.1159/000486542, PubMed 29486477

Tilz RR, Lenarczyk R, Scherr D, Haugaa KH, Iliodromitis K, Pürerfellner H, Kiliszek M, Dagres N (2018)
Management of ventricular tachycardia in the ablation era: results of the European Heart Rhythm Association Survey
Europace, 20 (1), 209-213
DOI 10.1093/europace/eux332, PubMed 29186419

Aalen J, Storsten P, Remme EW, Sirnes PA, Gjesdal O, Larsen CK, Kongsgaard E, Boe E, Skulstad H, Hisdal J, Smiseth OA (2018)
Afterload Hypersensitivity in Patients With Left Bundle Branch Block
JACC Cardiovasc Imaging (in press)
DOI 10.1016/j.jcmg.2017.11.025, PubMed 29361486

 
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