Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2017 from OUS - Institute for Surgical Research ISR

41 publications found

Abadpour S, Göpel SO, Schive SW, Korsgren O, Foss A, Scholz H (2017)
Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis
Sci Rep, 7 (1), 1575
DOI 10.1038/s41598-017-01805-1, PubMed 28484241

Behnan J, Stangeland B, Langella T, Finocchiaro G, Tringali G, Meling TR, Murrell W (2017)
Identification and characterization of a new source of adult human neural progenitors
Cell Death Dis, 8 (8), e2991
DOI 10.1038/cddis.2017.368, PubMed 28796246

Bersvendsen J, Orderud F, Lie Ø, Massey RJ, Fosså K, Estépar RSJ, Urheim S, Samset E (2017)
Semiautomated biventricular segmentation in three-dimensional echocardiography by coupled deformable surfaces
J Med Imaging (Bellingham), 4 (2), 024005
DOI 10.1117/1.JMI.4.2.024005, PubMed 28560243

Brandhorst D, Brandhorst H, Acreman S, Schive SW, Bjørnson Scholz H, Johnson PRV (2017)
Hypoxia-Induced Damage in Human Islets Is Reduced With the Use of Mesenchymal Stem Cell-Preconditioned Medium
Transplant Proc, 49 (10), 2330-2332
DOI 10.1016/j.transproceed.2017.11.003, PubMed 29198672

Broch K, de Marchi SF, Massey R, Hisdal J, Aakhus S, Gullestad L, Urheim S (2017)
Left Ventricular Contraction Pattern in Chronic Aortic Regurgitation and Preserved Ejection Fraction: Simultaneous Stress-Strain Analysis by Three-Dimensional Echocardiography
J Am Soc Echocardiogr, 30 (4), 422-430.e2
DOI 10.1016/j.echo.2016.11.012, PubMed 28065583

Brun OL, Månsson L, Nordsletten L (2017)
The direct anterior minimal invasive approach in total hip replacement: a prospective departmental study on the learning curve
Hip Int, 28 (2), 156-160
DOI 10.5301/hipint.5000542, PubMed 29048696

Chambers JB, Garbi M, Nieman K, Myerson S, Pierard LA, Habib G, Zamorano JL, Edvardsen T, Lancellotti P, This document was reviewed by members of the 2014—16 EACVI Scientific Documents Committee:, Delgado V, Cosyns B, Donal E, Dulgheru R, Galderisi M, Lombardi M, Muraru D, Kauffmann P, Cardim N, Haugaa K, Rosenhek R (2017)
Appropriateness criteria for the use of cardiovascular imaging in heart valve disease in adults: a European Association of Cardiovascular Imaging report of literature review and current practice
Eur Heart J Cardiovasc Imaging, 18 (5), 489-498
DOI 10.1093/ehjci/jew309, PubMed 28586420

de Lange C, D Saugstad O, Solberg R (2017)
Assessment of cerebral perfusion with contrast-enhanced ultrasound during constriction of the neck mimicking malposition of the BD Odon Device™: a study in newborn piglets
BJOG, 124 Suppl 4, 26-34
DOI 10.1111/1471-0528.14751, PubMed 28940870

Dejgaard LA, Haland TF, Lie OH, Ribe M, Bjune T, Leren IS, Berge KE, Edvardsen T, Haugaa KH (2017)
Data on exercise and cardiac imaging in a patient cohort with hypertrophic cardiomyopathy
Data Brief, 15, 30-39
DOI 10.1016/j.dib.2017.08.018, PubMed 28971120

Dhondup Y, Sjaastad I, Sandanger Ø, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang L, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE (2017)
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
DOI 10.1155/2017/9450439, PubMed 28490840

Donal E, Delgado V, Magne J, Bucciarelli-Ducci C, Leclercq C, Cosyns B, Sitges M, Edvardsen T, Sade E, Stankovic I, Agricola E, Galderisi M, Lancellotti P, Hernandez A, Plein S, Muraru D, Schwammenthal E, Hindricks G, Popescu BA, Habib G (2017)
Rational and design of EuroCRT: an international observational study on multi-modality imaging and cardiac resynchronization therapy
Eur Heart J Cardiovasc Imaging, 18 (10), 1120-1127
DOI 10.1093/ehjci/jex021, PubMed 28329299

Fumagalli S, Potpara TS, Bjerregaard Larsen T, Haugaa KH, Dobreanu D, Proclemer A, Dagres N (2017)
Frailty syndrome: an emerging clinical problem in the everyday management of clinical arrhythmias. The results of the European Heart Rhythm Association survey
Europace, 19 (11), 1896-1902
DOI 10.1093/europace/eux288, PubMed 29040554

Gilljam T, Haugaa KH, Jensen HK, Svensson A, Bundgaard H, Hansen J, Dellgren G, Gustafsson F, Eiskjær H, Andreassen AK, Sjögren J, Edvardsen T, Holst AG, Svendsen JH, Platonov PG (2017)
Heart transplantation in arrhythmogenic right ventricular cardiomyopathy - Experience from the Nordic ARVC Registry
Int J Cardiol, 250, 201-206
DOI 10.1016/j.ijcard.2017.10.076, PubMed 29107359

Haland TF, Hasselberg NE, Almaas VM, Dejgaard LA, Saberniak J, Leren IS, Berge KE, Haugaa KH, Edvardsen T (2017)
The systolic paradox in hypertrophic cardiomyopathy
Open Heart, 4 (1), e000571
DOI 10.1136/openhrt-2016-000571, PubMed 28674623

Hals I, Ohki T, Singh R, Ma Z, Björklund A, Balasuriya C, Scholz H, Grill V (2017)
Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates
Physiol Rep, 5 (19)
DOI 10.14814/phy2.13447, PubMed 29038359

Haugaa KH, Basso C, Badano LP, Bucciarelli-Ducci C, Cardim N, Gaemperli O, Galderisi M, Habib G, Knuuti J, Lancellotti P, McKenna W, Neglia D, Popescu BA, Edvardsen T, , (2017)
Comprehensive multi-modality imaging approach in arrhythmogenic cardiomyopathy-an expert consensus document of the European Association of Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging, 18 (3), 237-253
DOI 10.1093/ehjci/jew229, PubMed 28069601

Haugaa KH, Tilz R, Boveda S, Dobreanu D, Sciaraffia E, Mansourati J, Papiashvili G, Dagres N (2017)
Implantable cardioverter defibrillator use for primary prevention in ischaemic and non-ischaemic heart disease-indications in the post-DANISH trial era: results of the European Heart Rhythm Association survey
Europace, 19 (4), 660-664
DOI 10.1093/europace/eux089, PubMed 28431077

Ingvaldsen CA, Bosse G, Mynarek GK, Berg T, Tindholdt TT, Tønseth KA (2017)
Donor-Site Morbidity After DIEAP Flap Breast Reconstruction-A 2-Year Postoperative Computed Tomography Comparison
Plast Reconstr Surg Glob Open, 5 (7), e1405
DOI 10.1097/GOX.0000000000001405, PubMed 28831346

Kozlowski P, Urheim S, Samset E (2017)
EVALUATION OF A MULTI-VIEW AUTOSTEREOSCOPIC REAL-TIME 3D ULTRASOUND SYSTEM FOR MINIMALLY INVASIVE CARDIAC SURGERY GUIDANCE
2017 IEEE 14TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2017), 604-607

Kuligowski J, Solberg R, Sánchez-Illana Á, Pankratov L, Parra-Llorca A, Quintás G, Saugstad OD, Vento M (2017)
Plasma metabolite score correlates with Hypoxia time in a newly born piglet model for asphyxia
Redox Biol, 12, 1-7
DOI 10.1016/j.redox.2017.02.002, PubMed 28209514

Kvisvik B, Morkrid L, Rosjo H, Cvancarova M, Rowe AD, Eek C, Bendz B, Edvardsen T, Gravning J (2017)
High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis
Acta Bioquim. Clin. Latinoam., 51 (3), 395-407

Lai Q, Feys E, Karam V, Adam R, Klempnauer J, Oliverius M, Mazzaferro V, Pascher A, Remiszewski P, Isoniemi H, Pirenne J, Foss A, Ericzon BG, Markovic S, Lerut JP, European Liver Intestine Transplant Association (ELITA) (2017)
Hepatic Epithelioid Hemangioendothelioma and Adult Liver Transplantation: Proposal for a Prognostic Score Based on the Analysis of the ELTR-ELITA Registry
Transplantation, 101 (3), 555-564
DOI 10.1097/TP.0000000000001603, PubMed 28212256

Lenarczyk R, Potpara TS, Haugaa KH, Deharo JC, Hernandez-Madrid A, Del Carmen Exposito Pineda M, Kiliszek M, Dagres N (2017)
Approach to cardio-oncologic patients with special focus on patients with cardiac implantable electronic devices planned for radiotherapy: results of the European Heart Rhythm Association survey
Europace, 19 (9), 1579-1584
DOI 10.1093/europace/eux195, PubMed 28934410

Leren IS, Saberniak J, Haland TF, Edvardsen T, Haugaa KH (2017)
Combination of ECG and Echocardiography for Identification of Arrhythmic Events in Early ARVC
JACC-Cardiovasc. Imag., 10 (5), 504-513

Mohammed N, Ceprian M, Jimenez L, Pazos MR, Martínez-Orgado J (2017)
Neuroprotective Effects of Cannabidiol in Hypoxic Ischemic Insult. The Therapeutic Window in Newborn Mice
CNS Neurol Disord Drug Targets, 16 (1), 102-108
DOI 10.2174/1871527315666160927110305, PubMed 27686886

Nestvold J, Wang MY, Camilio KA, Zinöcker S, Tjelle TE, Lindberg A, Haug BE, Kvalheim G, Sveinbjørnsson B, Rekdal Ø (2017)
Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model
Oncoimmunology, 6 (8), e1338236
DOI 10.1080/2162402X.2017.1338236, PubMed 28920000

Orstavik K, Garfelt B, Leren TP, Saberniak J, Haugaa K, Jonsrud C (2017)
A 50 year old man with proximal power failure and heart disease
Tidsskr. Nor. Laegeforen., 137 (16), 1206-1209

Pedrosa J, Queiros S, Bernard O, Engvall J, Edvardsen T, Nagel E, D'hooge J (2017)
Fast and Fully Automatic Left Ventricular Segmentation and Tracking in Echocardiography Using Shape-Based B-Spline Explicit Active Surfaces
IEEE Trans Med Imaging, 36 (11), 2287-2296
DOI 10.1109/TMI.2017.2734959, PubMed 28783626

Ruddox V, Sandven I, Munkhaugen J, Skattebu J, Edvardsen T, Otterstad JE (2017)
Atrial fibrillation and the risk for myocardial infarction, all-cause mortality and heart failure: A systematic review and meta-analysis
Eur J Prev Cardiol, 24 (14), 1555-1566
DOI 10.1177/2047487317715769, PubMed 28617620

Sánchez-Illana Á, Solberg R, Lliso I, Pankratov L, Quintás G, Saugstad OD, Vento M, Kuligowski J (2017)
Assessment of phospholipid synthesis related biomarkers for perinatal asphyxia: a piglet study
Sci Rep, 7, 40315
DOI 10.1038/srep40315, PubMed 28071721

Schive SW, Mirlashari MR, Hasvold G, Wang M, Josefsen D, Gullestad HP, Korsgren O, Foss A, Kvalheim G, Scholz H (2017)
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
Cell Med, 9 (3), 103-116
DOI 10.3727/215517917X693401, PubMed 28713640

Senior R, Becher H, Monaghan M, Agati L, Zamorano J, Vanoverschelde JL, Nihoyannopoulos P, Edvardsen T, Lancellotti P, , (2017)
Clinical practice of contrast echocardiography: recommendation by the European Association of Cardiovascular Imaging (EACVI) 2017
Eur Heart J Cardiovasc Imaging, 18 (11), 1205-1205af
DOI 10.1093/ehjci/jex182, PubMed 28950366

Shi JH, Hammarström C, Grzyb K, Line PD (2017)
Experimental evaluation of liver regeneration patterns and liver function following ALPPS
BJS Open, 1 (3), 84-96
DOI 10.1002/bjs5.18, PubMed 29951610

Smiseth OA (2017)
Evaluation of left ventricular diastolic function: state of the art after 35 years with Doppler assessment
J Echocardiogr, 16 (2), 55-64
DOI 10.1007/s12574-017-0364-2, PubMed 29236226

Solberg R, Longini M, Proietti F, Perrone S, Felici C, Porta A, Saugstad OD, Buonocore G (2017)
DHA Reduces Oxidative Stress after Perinatal Asphyxia: A Study in Newborn Piglets
Neonatology, 112 (1), 1-8
DOI 10.1159/000454982, PubMed 28142140

Stokke TM, Hasselberg NE, Smedsrud MK, Sarvari SI, Haugaa KH, Smiseth OA, Edvardsen T, Remme EW (2017)
Geometry as a Confounder When Assessing Ventricular Systolic Function: Comparison Between Ejection Fraction and Strain
J Am Coll Cardiol, 70 (8), 942-954
DOI 10.1016/j.jacc.2017.06.046, PubMed 28818204

Strand-Amundsen RJ, Reims HM, Tronstad C, Kalvøy H, Martinsen ØG, Høgetveit JO, Ruud TE, Tønnessen TI (2017)
Ischemic small intestine-in vivo versus ex vivo bioimpedance measurements
Physiol Meas, 38 (5), 715-728
DOI 10.1088/1361-6579/aa67b7, PubMed 28319030

Tilz RR, Potpara T, Chen J, Dobreanu D, Larsen TB, Haugaa KH, Dagres N (2017)
Left atrial appendage occluder implantation in Europe: indications and anticoagulation post-implantation. Results of the European Heart Rhythm Association Survey
Europace, 19 (10), 1737-1742
DOI 10.1093/europace/eux254, PubMed 29016910

Timmermann V, Dejgaard LA, Haugaa KH, Edwards AG, Sundnes J, McCulloch AD, Wall ST (2017)
An integrative appraisal of mechano-electric feedback mechanisms in the heart
Prog Biophys Mol Biol, 130 (Pt B), 404-417
DOI 10.1016/j.pbiomolbio.2017.08.008, PubMed 28851517

Turkowski KL, Tester DJ, Bos JM, Haugaa KH, Ackerman MJ (2017)
Whole exome sequencing with genomic triangulation implicates CDH2-encoded N-cadherin as a novel pathogenic substrate for arrhythmogenic cardiomyopathy
Congenit Heart Dis, 12 (2), 226-235
DOI 10.1111/chd.12462, PubMed 28326674

Tønseth KA, Sneistrup C, Berg TM (2017)
Prostaglandin E1 Increases Microcirculation in Random Pattern Flaps on Rats Measured with Laser Doppler Perfusion Imaging
Plast Reconstr Surg Glob Open, 5 (1), e1202
DOI 10.1097/GOX.0000000000001202, PubMed 28203503

 
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