Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Institute for Experimental Medical Research IEMR

8 publications found

Brynildsen J, Petäjä L, Myhre PL, Lyngbakken MN, Nygård S, Stridsberg M, Christensen G, Ottesen AH, Pettilä V, Omland T, Røsjø H (2019)
Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
Crit Care Med (in press)
DOI 10.1097/CCM.0000000000003670, PubMed 30730440

de Boer RA, De Keulenaer G, Bauersachs J, Brutsaert D, Cleland JG, Diez J, Du XJ, Ford P, Heinzel FR, Lipson KE, McDonagh T, Lopez-Andres N, Lunde IG, Lyon AR, Pollesello P, Prasad SK, Tocchetti CG, Mayr M, Sluijter JPG, Thum T, Tschöpe C, Zannad F, Zimmermann WH, Ruschitzka F, Filippatos G et al. (2019)
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology
Eur J Heart Fail, 21 (3), 272-285
DOI 10.1002/ejhf.1406, PubMed 30714667

Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279

Lipsett DB, Frisk M, Aronsen JM, Nordén ES, Buonarati OR, Cataliotti A, Hell JW, Sjaastad I, Christensen G, Louch WE (2019)
Cardiomyocyte substructure reverts to an immature phenotype during heart failure
J Physiol (in press)
DOI 10.1113/JP277273, PubMed 30707448

Louch WE (2019)
Channel surfing: new insights into plasticity of excitation-contraction coupling
J Physiol (in press)
DOI 10.1113/JP277783, PubMed 30854650

Sheard TMD, Hurley ME, Colyer J, White E, Norman R, Pervolaraki E, Narayanasamy KK, Hou Y, Kirton HM, Yang Z, Hunter L, Shim JU, Clowsley AH, Smith AJ, Baddeley D, Soeller C, Colman MA, Jayasinghe I (2019)
Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy
ACS Nano, 13 (2), 2143-2157
DOI 10.1021/acsnano.8b08742, PubMed 30715853

Skogestad J, Lines GT, Louch WE, Sejersted OM, Sjaastad I, Aronsen JM (2019)
Evidence for heterogeneous subsarcolemmal Na+ levels in rat ventricular myocytes
Am J Physiol Heart Circ Physiol (in press)
DOI 10.1152/ajpheart.00637.2018, PubMed 30657726

Toepfer CN, Wakimoto H, Garfinkel AC, McDonough B, Liao D, Jiang J, Tai AC, Gorham JM, Lunde IG, Lun M, Lynch TL, McNamara JW, Sadayappan S, Redwood CS, Watkins HC, Seidman JG, Seidman CE (2019)
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin
Sci Transl Med, 11 (476)
DOI 10.1126/scitranslmed.aat1199, PubMed 30674652

 
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