Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2016 from OUS - Institute for Cancer Genetics and Informatics
45 publications found
Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva
Oncotarget, 7 (51), 85058-85062
DOI 10.18632/oncotarget.13187, PubMed 27835588
Molecular characterization of the t(4;12)(q27~28;q14~15) chromosomal rearrangement in lipoma
Oncol Lett, 12 (3), 1701-1704
DOI 10.3892/ol.2016.4834, PubMed 27588119
A novel truncated form of HMGA2 in tumors of the ovaries
Oncol Lett, 12 (2), 1559-1563
DOI 10.3892/ol.2016.4805, PubMed 27446471
MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma
Oncotarget, 7 (34), 55128-55140
DOI 10.18632/oncotarget.10422, PubMed 27391157
Discovery of miRNAs and Their Corresponding miRNA Genes in Atlantic Cod (Gadus morhua): Use of Stable miRNAs as Reference Genes Reveals Subgroups of miRNAs That Are Highly Expressed in Particular Organs
PLoS One, 11 (4), e0153324
DOI 10.1371/journal.pone.0153324, PubMed 27128807
Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency
Oncogene, 36 (4), 570-584
DOI 10.1038/onc.2016.230, PubMed 27345406
Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
J Immunol, 196 (3), 1400-11
DOI 10.4049/jimmunol.1501434, PubMed 26746188
Profiling networks of distinct immune-cells in tumors
BMC Bioinformatics, 17 (1), 263
DOI 10.1186/s12859-016-1141-3, PubMed 27377892
Progesterone Receptor Expression Is an Independent Prognosticator in FIGO Stage I Uterine Leiomyosarcoma
Am J Clin Pathol, 145 (4), 449-58
DOI 10.1093/ajcp/aqw030, PubMed 27149024
Altered gene expression and possible immunodeficiency in cases of sudden infant death syndrome
Pediatr Res, 80 (1), 77-84
DOI 10.1038/pr.2016.45, PubMed 26959483
Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients
PLoS One, 11 (5), e0156259
DOI 10.1371/journal.pone.0156259, PubMed 27244197
Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Clin Cancer Res, 22 (16), 4067-76
DOI 10.1158/1078-0432.CCR-15-2322, PubMed 27012812
Subtype-specific micro-RNA expression signatures in breast cancer progression
Int J Cancer, 139 (5), 1117-28
DOI 10.1002/ijc.30142, PubMed 27082076
TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
Front Genet, 7, 85
DOI 10.3389/fgene.2016.00085, PubMed 27242894
Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
Pancreas, 45 (8), 1196-203
DOI 10.1097/MPA.0000000000000610, PubMed 26918873
Characteristics of Blood Vessels in Female Genital Schistosomiasis: Paving the Way for Objective Diagnostics at the Point of Care
PLoS Negl Trop Dis, 10 (4), e0004628
DOI 10.1371/journal.pntd.0004628, PubMed 27073857
Chromatin changes predict recurrence after radical prostatectomy
Br J Cancer, 114 (11), 1243-50
DOI 10.1038/bjc.2016.96, PubMed 27124335
Changes in Chromatin Structure in Curettage Specimens Identifies High-Risk Patients in Endometrial Cancer
Cancer Epidemiol Biomarkers Prev, 26 (1), 61-67
DOI 10.1158/1055-9965.EPI-16-0215, PubMed 27587790
Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice variant in insulinomas
Oncol Rep, 36 (5), 2653-2662
DOI 10.3892/or.2016.5132, PubMed 27667266
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Gut, 66 (4), 611-619
DOI 10.1136/gutjnl-2015-310500, PubMed 26887816
Poor concordance between CA-125 and RECIST at the time of disease progression in patients with platinum-resistant ovarian cancer: analysis of the AURELIA trial
Ann Oncol, 27 (8), 1505-10
DOI 10.1093/annonc/mdw238, PubMed 27407100
Gender, High-Sensitivity Troponin I, and the Risk of Cardiovascular Events (from the Nord-Trøndelag Health Study)
Am J Cardiol, 118 (6), 816-821
DOI 10.1016/j.amjcard.2016.06.043, PubMed 27453509
Impact of Smoking on Circulating Cardiac Troponin I Concentrations and Cardiovascular Events in the General Population: The HUNT Study (Nord-Trøndelag Health Study)
Circulation, 134 (24), 1962-1972
DOI 10.1161/CIRCULATIONAHA.116.023726, PubMed 27815376
Cytogenetic and molecular profile of endometrial stromal sarcoma
Genes Chromosomes Cancer, 55 (11), 834-46
DOI 10.1002/gcc.22380, PubMed 27219024
Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
Gut, 66 (9), 1657-1664
DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
EBioMedicine, 8, 103-116
DOI 10.1016/j.ebiom.2016.04.018, PubMed 27428423
Novel fusion genes and chimeric transcripts in ependymal tumors
Genes Chromosomes Cancer, 55 (12), 944-953
DOI 10.1002/gcc.22392, PubMed 27401149
Fusion of the HMGA2 and C9orf92 genes in myolipoma with t(9;12)(p22;q14)
Diagn Pathol, 11, 22
DOI 10.1186/s13000-016-0472-8, PubMed 26857357
Rare MLL-ELL fusion transcripts in childhood acute myeloid leukemia-association with young age and myeloid sarcomas?
Exp Hematol Oncol, 5, 8
DOI 10.1186/s40164-016-0037-2, PubMed 26949571
Recurrent fusion of the genes FN1 and ALK in gastrointestinal leiomyomas
Mod Pathol, 29 (11), 1415-1423
DOI 10.1038/modpathol.2016.129, PubMed 27469327
Gene fusions AHRR-NCOA2, NCOA2-ETV4, ETV4-AHRR, P4HA2-TBCK, and TBCK-P4HA2 resulting from the translocations t(5;8;17)(p15;q13;q21) and t(4;5)(q24;q31) in a soft tissue angiofibroma
Oncol Rep, 36 (5), 2455-2462
DOI 10.3892/or.2016.5096, PubMed 27633981
RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Oncol Rep, 36 (5), 2481-2488
DOI 10.3892/or.2016.5119, PubMed 27667292
Efficacy and safety of fosaprepitant for the prevention of nausea and emesis during 5 weeks of chemoradiotherapy for cervical cancer (the GAND-emesis study): a multinational, randomised, placebo-controlled, double-blind, phase 3 trial
Lancet Oncol, 17 (4), 509-518
DOI 10.1016/S1470-2045(15)00615-4, PubMed 26952945
STAMPing at the crossroads of normal physiology and disease states
Mol Cell Endocrinol, 425, 26-36
DOI 10.1016/j.mce.2016.02.013, PubMed 26911931
Cancer Prognosis Defined by the Combined Analysis of 8q, PTEN and ERG
Transl Oncol, 9 (6), 575-582
DOI 10.1016/j.tranon.2016.08.005, PubMed 27916292
Bilateral ovarian carcinomas differ in the expression of metastasis-related genes
Oncol Lett, 13 (1), 184-190
DOI 10.3892/ol.2016.5384, PubMed 28123539
L1CAM as a prognostic marker in stage I endometrial cancer: a validation study
BMC Cancer, 16, 596
DOI 10.1186/s12885-016-2631-4, PubMed 27488577
Safety and efficacy of single-agent bevacizumab-containing therapy in elderly patients with platinum-resistant recurrent ovarian cancer: Subgroup analysis of the randomised phase III AURELIA trial
Gynecol Oncol, 144 (1), 65-71
DOI 10.1016/j.ygyno.2016.11.006, PubMed 27871723
Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study
Tumour Biol, 37 (8), 11065-72
DOI 10.1007/s13277-015-4742-y, PubMed 26906551
Prostate cancer and the unfolded protein response
Oncotarget, 7 (33), 54051-54066
DOI 10.18632/oncotarget.9912, PubMed 27303918
Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element
J Biol Chem, 291 (22), 11899-910
DOI 10.1074/jbc.M115.684480, PubMed 27056330
Prognostic and predictive effects of primary versus secondary platinum resistance for bevacizumab treatment for platinum-resistant ovarian cancer in the AURELIA trial
Ann Oncol, 27 (9), 1733-9
DOI 10.1093/annonc/mdw236, PubMed 27287207
High frequency of occupied attB regions in Norwegian Staphylococcus aureus isolates supports a two-step MRSA screening algorithm
Eur J Clin Microbiol Infect Dis, 36 (1), 65-74
DOI 10.1007/s10096-016-2771-0, PubMed 27638009
Persistent bone marrow depression following short-term treatment with temozolomide
BMJ Case Rep, 2016
DOI 10.1136/bcr-2016-215797, PubMed 27130558
VOLIN and KJON-Two novel hyperdiploid myeloma cell lines
Genes Chromosomes Cancer, 55 (11), 890-901
DOI 10.1002/gcc.22388, PubMed 27311012