Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Oncology

51 publications found

Abravan A, Eide HA, Helland Å, Malinen E (2020)
Radiotherapy-related lymphopenia in patients with advanced non-small cell lung cancer receiving palliative radiotherapy
Clin Transl Radiat Oncol, 22, 15-21
DOI 10.1016/j.ctro.2020.02.005, PubMed 32181373

Al-Haidari G, Skovlund E, Undseth C, Rekstad BL, Larsen SG, Åsli LM, Dueland S, Malinen E, Guren MG (2020)
Re-irradiation for recurrent rectal cancer - a single-center experience
Acta Oncol, 59 (5), 534-540
DOI 10.1080/0284186X.2020.1725111, PubMed 32056476

Autio M, Leivonen SK, Brück O, Mustjoki S, Jørgensen JM, Karjalainen-Lindsberg ML, Beiske K, Holte H, Pellinen T, Leppä S (2020)
Immune cell constitution in the tumor microenvironment predicts the outcome in diffuse large B-cell lymphoma
Haematologica (in press)
DOI 10.3324/haematol.2019.243626, PubMed 32079690

Bai B, Myklebust JH, Wälchli S (2020)
Gene Editing in B-Lymphoma Cell Lines Using CRISPR/Cas9 Technology
Methods Mol Biol, 2115, 445-454
DOI 10.1007/978-1-0716-0290-4_25, PubMed 32006416

Bell L, Holloway L, Bruheim K, Petrič P, Kirisits C, Tanderup K, Pötter R, Vinod S, Lim K, Pogson E, Metcalfe P, Hellebust TP (2020)
Dose planning variations related to delineation variations in MRI-guided brachytherapy for locally advanced cervical cancer
Brachytherapy, 19 (2), 146-153
DOI 10.1016/j.brachy.2020.01.002, PubMed 32067884

Bjerkeset E, Röhrl K, Schou-Bredal I (2020)
Symptom cluster of pain, fatigue, and psychological distress in breast cancer survivors: prevalence and characteristics
Breast Cancer Res Treat, 180 (1), 63-71
DOI 10.1007/s10549-020-05522-8, PubMed 31938939

Breugom AJ, Bastiaannet E, Guren MG, Kørner H, Boelens PG, Dekker FW, Kapiteijn E, Gelderblom H, Larsen IK, Liefers GJ, van de Velde CJH (2020)
Treatment strategies and overall survival for incurable metastatic colorectal cancer - A EURECCA international comparison including 21,196 patients from the Netherlands and Norway
Eur J Surg Oncol (in press)
DOI 10.1016/j.ejso.2020.02.005, PubMed 32151531

Dagenborg VJ, Marshall SE, Yaqub S, Grzyb K, Boye K, Lund-Iversen M, Høye E, Berstad AE, Fretland ÅA, Edwin B, Ree AH, Flatmark K (2020)
Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases
Cancer Biol Ther, 21 (5), 432-440
DOI 10.1080/15384047.2020.1721252, PubMed 32098573

Dahl AA, Brennhovd B, Fosså SD, Axcrona K (2020)
A cross-sectional study of current work ability after radical prostatectomy
BMC Urol, 20 (1), 9
DOI 10.1186/s12894-020-0579-9, PubMed 32005115

Eide IJZ, Helland Å, Ekman S, Mellemgaard A, Hansen KH, Cicenas S, Koivunen J, Grønberg BH, Brustugun OT (2020)
Osimertinib in T790M-positive and -negative patients with EGFR-mutated advanced non-small cell lung cancer (the TREM-study)
Lung Cancer, 143, 27-35 (in press)
DOI 10.1016/j.lungcan.2020.03.009, PubMed 32200138

Ekström M, Palmqvist S, Currow DC, Sjøgren P, Kurita GP, Jakobsen G, Kaasa S, Hjermstad M (2020)
Mild to moderate cognitive impairment does not affect the ability to self-report important symptoms in cancer patients: a prospective longitudinal multi-national study (EPCCS)
J Pain Symptom Manage (in press)
DOI 10.1016/j.jpainsymman.2020.03.007, PubMed 32179133

Eskelund CW, Husby S, Favero F, Klausen TW, Rodriguez-Gonzalez FG, Kolstad A, Pedersen LB, Räty RK, Geisler CH, Jerkeman M, Weischenfeldt J, Grønbæk K (2020)
Clonal hematopoiesis evolves from pre-treatment clones and stabilizes after end of chemotherapy in patients with MCL
Blood (in press)
DOI 10.1182/blood.2019003539, PubMed 32181815

Flem-Karlsen K, Nyakas M, Farstad IN, McFadden E, Wernhoff P, Jacobsen KD, Flørenes VA, Mælandsmo GM (2020)
Soluble AXL as a marker of disease progression and survival in melanoma
PLoS One, 15 (1), e0227187
DOI 10.1371/journal.pone.0227187, PubMed 31917795

Fosså A, Smeland KH, Fluge Ø, Tronstad KJ, Loge JH, Midttun Ø, Ueland PM, Kiserud CE (2020)
Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue
PLoS One, 15 (1), e0227384
DOI 10.1371/journal.pone.0227384, PubMed 31923274

Fredheim OM, Skurtveit S, Loge JH, Sjøgren P, Handal M, Hjellvik V (2020)
Prescription of analgesics to long-term survivors of cancer in early adulthood, adolescence, and childhood in Norway: a national cohort study
Pain (in press)
DOI 10.1097/j.pain.0000000000001800, PubMed 31923046

Georgiesh T, Boye K, Bjerkehagen B (2020)
A novel risk score to predict early and late recurrence in solitary fibrous tumour
Histopathology (in press)
DOI 10.1111/his.14078, PubMed 31991494

Grindedal EM, Jørgensen K, Olsson P, Gravdehaug B, Lurås H, Schlichting E, Vamre T, Wangensteen T, Heramb C, Mæhle L (2020)
Mainstreamed genetic testing of breast cancer patients in two hospitals in South Eastern Norway
Fam Cancer, 19 (2), 133-142
DOI 10.1007/s10689-020-00160-x, PubMed 32002722

Hestevik CH, Molin M, Debesay J, Bergland A, Bye A (2020)
Older patients' and their family caregivers' perceptions of food, meals and nutritional care in the transition between hospital and home care: a qualitative study
BMC Nutr, 6, 11
DOI 10.1186/s40795-020-00335-w, PubMed 32206325

Hompland I, Fauske L, Lorem GF, Bruland ØS (2020)
Use of a simple form to facilitate communication on long-term consequences of treatment in sarcoma survivors
Clin Sarcoma Res, 10, 2
DOI 10.1186/s13569-019-0124-3, PubMed 31969978

Hugenschmidt H, Labori KJ, Brunborg C, Verbeke CS, Seeberg LT, Schirmer CB, Renolen A, Borgen EF, Naume B, Wiedswang G (2020)
Circulating Tumor Cells are an Independent Predictor of Shorter Survival in Patients Undergoing Resection for Pancreatic and Periampullary Adenocarcinoma
Ann Surg, 271 (3), 549-558
DOI 10.1097/SLA.0000000000003035, PubMed 30216219

Inderberg EM, Wälchli S (2020)
Sympathetic improvement of cancer vaccine efficacy
Hum Vaccin Immunother
DOI 10.1080/21645515.2019.1703456, PubMed 31977269

Inderberg EM, Wälchli S (2020)
Long-term surviving cancer patients as a source of therapeutic TCR
Cancer Immunol Immunother (in press)
DOI 10.1007/s00262-019-02468-9, PubMed 31915853

Jakobsen LH, Ellin F, Smeland KB, Wästerlid T, Christensen JH, Jørgensen JM, Josefsson PL, Øvlisen AK, Holte H, Blaker YN, Grauslund JH, Bjørn J, Molin D, Lagerlöf I, Smedby KE, Colvin K, Thanarajasingam G, Maurer MJ, Habermann TM, Song KW, Zhu KY, Gerrie AS, Cheah CY, El-Galaly TC (2020)
Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy: an international study of 264 real-world patients
Br J Haematol
DOI 10.1111/bjh.16425, PubMed 32017050

Jeanmougin M, Håvik AB, Cekaite L, Brandal P, Sveen A, Meling TR, Ågesen TH, Scheie D, Heim S, Lothe RA, Lind GE (2020)
Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
Mol Oncol (in press)
DOI 10.1002/1878-0261.12668, PubMed 32171051

Koller M, Shamieh O, Hjermstad MJ, Hornslien K, Young T, Chalk T, Ioannidis G, Harle A, Johnson CD, Tomaszewski KA, Serpentini S, Pinto M, van der Weijst L, Janssens A, Morag O, Chie WC, Arraras JI, Pompili C, Jungraithmayr W, Hechtner M, Katsochi D, Müller K, Gräfenstein L, Schulz C, Bottomley A et al. (2020)
Psychometric properties of the updated EORTC module for assessing quality of life in patients with lung cancer (QLQ-LC29): an international, observational field study
Lancet Oncol (in press)
DOI 10.1016/S1470-2045(20)30093-0, PubMed 32213338

Korvald C, L'Orange IC (2020)
Oncoplastic breast conserving surgery
Tidsskr. Nor. Laegeforen., 140 (3), 254-258

Korvald C, L'orange IC (2020)
Onkoplastisk brystbevarende kirurgi
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0371, PubMed 32105024

Larsson C, Groote I, Vardal J, Kleppestø M, Odland A, Brandal P, Due-Tønnessen P, Holme SS, Hope TR, Meling TR, Fosse E, Emblem KE, Bjørnerud A (2020)
Prediction of survival and progression in glioblastoma patients using temporal perfusion changes during radiochemotherapy
Magn Reson Imaging, 68, 106-112 (in press)
DOI 10.1016/j.mri.2020.01.012, PubMed 32004711

Lichtenegger FS, Schnorfeil FM, Rothe M, Deiser K, Altmann T, Bücklein VL, Köhnke T, Augsberger C, Konstandin NP, Spiekermann K, Moosmann A, Boehm S, Boxberg M, Heemskerk MH, Goerlich D, Wittmann G, Wagner B, Hiddemann W, Schendel DJ, Kvalheim G, Bigalke I, Subklewe M (2020)
Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: results of a phase I trial
Clin Transl Immunology, 9 (3), e1117
DOI 10.1002/cti2.1117, PubMed 32153780

Lilleheie I, Debesay J, Bye A, Bergland A (2020)
Informal caregivers' views on the quality of healthcare services provided to older patients aged 80 or more in the hospital and 30 days after discharge
BMC Geriatr, 20 (1), 97
DOI 10.1186/s12877-020-1488-1, PubMed 32164569

Lunde P, Bye A, Bergland A, Grimsmo J, Jarstad E, Nilsson BB (2020)
Long-term follow-up with a smartphone application improves exercise capacity post cardiac rehabilitation: A randomized controlled trial
Eur J Prev Cardiol, UNSP 2047487320905717
DOI 10.1177/2047487320905717, PubMed 32106713

Maziarz RT, Waller EK, Jaeger U, Fleury I, McGuirk J, Holte H, Jaglowski S, Schuster SJ, Bishop MR, Westin JR, Mielke S, Teshima T, Bachanova V, Foley SR, Borchmann P, Salles GA, Zhang J, Tiwari R, Pacaud LB, Ma Q, Tam CS (2020)
Patient-reported long-term quality of life after tisagenlecleucel in relapsed/refractory diffuse large B-cell lymphoma
Blood Adv, 4 (4), 629-637
DOI 10.1182/bloodadvances.2019001026, PubMed 32074277

Maaland AF, Saidi A, Torgue J, Heyerdahl H, Stallons TAR, Kolstad A, Dahle J (2020)
Targeted alpha therapy for chronic lymphocytic leukaemia and non-Hodgkin's lymphoma with the anti-CD37 radioimmunoconjugate 212Pb-NNV003
PLoS One, 15 (3), e0230526
DOI 10.1371/journal.pone.0230526, PubMed 32187209

Nome RV, Cvancarova Småstuen M, Bjøro T, Kiserud CE, Fosså SD (2020)
Longitudinal kidney function outcome in aging testicular cancer survivors
Acta Oncol, 59 (4), 467-474
DOI 10.1080/0284186X.2020.1724328, PubMed 32043400

Palmer DH, Valle JW, Ting Ma Y, Faluyi O, Neoptolemos JP, Jensen Gjertsen T, Iversen B, Amund Eriksen J, Møller AS, Aksnes AK, Miller R, Dueland S (2020)
TG01/GM-CSF and adjuvant gemcitabine in patients with resected RAS-mutant adenocarcinoma of the pancreas (CT TG01-01): a single-arm, phase 1/2 trial
Br J Cancer
DOI 10.1038/s41416-020-0752-7, PubMed 32063605

Panagopoulos I, Gorunova L, Johannsdottir IMR, Andersen K, Holth A, Beiske K, Heim S (2020)
Chromosome Translocation t(14;21)(q11;q22) Activates Both OLIG1 and OLIG2 in Pediatric T-cell Lymphoblastic Malignancies and May Signify Adverse Prognosis
Cancer Genomics Proteomics, 17 (1), 41-48
DOI 10.21873/cgp.20166, PubMed 31882550

Poeschel V, Held G, Ziepert M, Witzens-Harig M, Holte H, Thurner L, Borchmann P, Viardot A, Soekler M, Keller U, Schmidt C, Truemper L, Mahlberg R, Marks R, Hoeffkes HG, Metzner B, Dierlamm J, Frickhofen N, Haenel M, Neubauer A, Kneba M, Merli F, Tucci A, de Nully Brown P, Federico M et al. (2020)
Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial
Lancet, 394 (10216), 2271-2281
DOI 10.1016/S0140-6736(19)33008-9, PubMed 31868632

Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
Acta Oncol, 1-8 (in press)
DOI 10.1080/0284186X.2020.1742377, PubMed 32208873

Ryalen PC, Stensrud MJ, Fosså S, Røysland K (2020)
Causal inference in continuous time: an example on prostate cancer therapy
Biostatistics, 21 (1), 172-185
DOI 10.1093/biostatistics/kxy036, PubMed 30124773

Ryg U, Lilleby W, Hole KH, Lund-Iversen M, Switlyk MD (2020)
Local Recurrence of Prostate Cancer to the Intersphincteric Space: A Case Report
Urology (in press)
DOI 10.1016/j.urology.2020.03.009, PubMed 32199872

Skalleberg J, Småstuen MC, Oldenburg J, Osnes T, Fosså SD, Bunne M (2020)
The Relationship Between Cisplatin-related and Age-related Hearing Loss During an Extended Follow-up
Laryngoscope
DOI 10.1002/lary.28543, PubMed 32065408

Sonden ECB, Sebuodegard S, Korvald C, Lomo J, Schlichting E, Brandal SHB, Hofving S (2020)
Cosmetic breast implants and breast cancer
Tidsskr. Nor. Laegeforen., 140 (3), 236-241

Sondén ECB, Sebuødegård S, Korvald C, Lømo J, Schlichting E, Brandal SHB, Hofvind S (2020)
Kosmetiske brystimplantater og brystkreft
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0266, PubMed 32105043

Sondén ECB, Sebuødegård S, Korvald C, Lømo J, Schlichting E, Brandal SHB, Hofvind S (2020)
Rettelse: Kosmetiske brystimplantater og brystkreft
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.20.0163, PubMed 32192257

Stenberg VY, Juzeniene A, Chen Q, Yang X, Bruland ØS, Larsen RH (2020)
Preparation of the alpha-emitting prostate-specific membrane antigen targeted radioligand [212 Pb]Pb-NG001 for prostate cancer
J Labelled Comp Radiopharm, 63 (3), 129-143
DOI 10.1002/jlcr.3825, PubMed 31919866

Stensvold E, Stadskleiv K, Myklebust TÅ, Wesenberg F, Helseth E, Bechensteen AG, Brandal P (2020)
Unmet rehabilitation needs in 86% of Norwegian paediatric embryonal brain tumour survivors
Acta Paediatr
DOI 10.1111/apa.15188, PubMed 31977119

Thøgersen H, Møller B, Åsli LM, Bhargava S, Kvåle R, Fjellbirkeland L, Robsahm TE, Aaserud S, Babigumira R, Larsen IK (2020)
Waiting times and treatment following cancer diagnosis: comparison between immigrants and the Norwegian host population
Acta Oncol, 59 (4), 376-383
DOI 10.1080/0284186X.2019.1711167, PubMed 31920119

Umu SU, Langseth H, Keller A, Meese E, Helland Å, Lyle R, Rounge TB (2020)
A 10-year prediagnostic follow-up study shows that serum RNA signals are highly dynamic in lung carcinogenesis
Mol Oncol, 14 (2), 235-247
DOI 10.1002/1878-0261.12620, PubMed 31851411

VAN Vulpen JK, Sweegers MG, Peeters PHM, Courneya KS, Newton RU, Aaronson NK, Jacobsen PB, Galvão DA, Chinapaw MJ, Steindorf K, Irwin ML, Stuiver MM, Hayes S, Griffith KA, Mesters I, Knoop H, Goedendorp MM, Mutrie N, Daley AJ, McConnachie A, Bohus M, Thorsen L, Schulz KH, Short CE, James EL et al. (2020)
Moderators of Exercise Effects on Cancer-related Fatigue: A Meta-analysis of Individual Patient Data
Med Sci Sports Exerc, 52 (2), 303-314
DOI 10.1249/MSS.0000000000002154, PubMed 31524827

Weider T, Richardson SJ, Morgan NG, Paulsen TH, Dahl-Jørgensen K, Hammerstad SS (2020)
Upregulation of HLA Class I and Antiviral Tissue Responses in Hashimoto's Thyroiditis
Thyroid, 30 (3), 432-442
DOI 10.1089/thy.2019.0607, PubMed 31910110

Wälchli S, Sioud M (2020)
Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?
Methods Mol Biol, 2115, 407-417
DOI 10.1007/978-1-0716-0290-4_22, PubMed 32006413

 
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