Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Oncology

35 publications found

Bains SJ, Niehusmann PF, Meling TR, Saxhaug C, Züchner M, Brandal P (2019)
Disseminated central nervous system hemangioblastoma in a patient with no clinical or genetic evidence of von Hippel-Lindau disease-a case report and literature review
Acta Neurochir (Wien), 161 (2), 343-349
DOI 10.1007/s00701-019-03800-z, PubMed 30652202

Bennett MI, Kaasa S, Barke A, Korwisi B, Rief W, Treede RD, IASP Taskforce for the Classification of Chronic Pain (2019)
The IASP classification of chronic pain for ICD-11: chronic cancer-related pain
Pain, 160 (1), 38-44
DOI 10.1097/j.pain.0000000000001363, PubMed 30586069

Bergholtz H, Lien TG, Ursin G, Holmen MM, Helland Å, Sørlie T, Haakensen VD (2019)
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
J Mammary Gland Biol Neoplasia (in press)
DOI 10.1007/s10911-018-09423-x, PubMed 30613869

Bersvendsen HS, Haugnes HS, Fagerli UM, Fluge Ø, Holte H, Smeland KB, Wilsgaard T, Kiserud CE (2019)
Lifestyle behavior among lymphoma survivors after high-dose therapy with autologous hematopoietic stem cell transplantation, assessed by patient-reported outcomes
Acta Oncol, 1-10 (in press)
DOI 10.1080/0284186X.2018.1558370, PubMed 30696346

Biccler JL, Glimelius I, Eloranta S, Smeland KB, Brown PN, Jakobsen LH, Frederiksen H, Jerkeman M, Fosså A, Andersson TML, Holte H, Bøgsted M, El-Galaly TC, Smedby KE (2019)
Relapse Risk and Loss of Lifetime After Modern Combined Modality Treatment of Young Patients With Hodgkin Lymphoma: A Nordic Lymphoma Epidemiology Group Study
J Clin Oncol, 37 (9), 703-713
DOI 10.1200/JCO.18.01652, PubMed 30726176

Bowitz Lothe IM, Kleive D, Pomianowska E, Cvancarova M, Kure E, Dueland S, Gladhaug IP, Labori KJ (2019)
Clinical relevance of pancreatobiliary and intestinal subtypes of ampullary and duodenal adenocarcinoma: Pattern of recurrence, chemotherapy, and survival after pancreatoduodenectomy
Pancreatology, 19 (2), 316-324
DOI 10.1016/j.pan.2019.01.019, PubMed 30713128

Bøhn SH, Thorsen L, Kiserud CE, Fosså SD, Lie HC, Loge JH, Wisløff T, Haugnes HS, Reinertsen KV (2019)
Chronic fatigue and associated factors among long-term survivors of cancers in young adulthood
Acta Oncol, 1-10 (in press)
DOI 10.1080/0284186X.2018.1557344, PubMed 30696351

Camilio KA, Wang MY, Mauseth B, Waagene S, Kvalheim G, Rekdal Ø, Sveinbjørnsson B, Mælandsmo GM (2019)
Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
Breast Cancer Res, 21 (1), 9
DOI 10.1186/s13058-018-1092-x, PubMed 30670061

Escala-Garcia M, Guo Q, Dörk T, Canisius S, Keeman R, Dennis J, Beesley J, Lecarpentier J, Bolla MK, Wang Q, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Boeckx B, Bojesen SE, Bonanni B, Børresen-Dale AL et al. (2019)
Genome-wide association study of germline variants and breast cancer-specific mortality
Br J Cancer, 120 (6), 647-657
DOI 10.1038/s41416-019-0393-x, PubMed 30787463

Gjerset GM, Kiserud CE, Loge JH, Fosså SD, Wisløff T, Gudbergsson SB, Oldervoll LM, Thorsen L (2019)
Changes in fatigue, health-related quality of life and physical activity after a one-week educational program for cancer survivors
Acta Oncol, 1-8 (in press)
DOI 10.1080/0284186X.2018.1562210, PubMed 30862228

Gjerset GM, Tendille M, Skaali T, Kiserud CE, Dahl AA, Gudbergsson SB, Thorsen L (2019)
Gender differences in health status and benefits of a one-week educational programme for caregivers of cancer patients
Eur J Cancer Care (Engl), 28 (2), e12992
DOI 10.1111/ecc.12992, PubMed 30652372

Hoeben BA, Carrie C, Timmermann B, Mandeville HC, Gandola L, Dieckmann K, Ramos Albiac M, Magelssen H, Lassen-Ramshad Y, Ondrová B, Ajithkumar T, Alapetite C, Balgobind BV, Bolle S, Cameron AL, Davila Fajardo R, Dietzsch S, Dumont Lecomte D, van den Heuvel-Eibrink MM, Kortmann RD, Laprie A, Melchior P, Padovani L, Rombi B, Scarzello G et al. (2019)
Management of vertebral radiotherapy dose in paediatric patients with cancer: consensus recommendations from the SIOPE radiotherapy working group
Lancet Oncol, 20 (3), e155-e166
DOI 10.1016/S1470-2045(19)30034-8, PubMed 30842059

Josefsson SE, Beiske K, Blaker YN, Førsund MS, Holte H, Østenstad B, Kimby E, Köksal H, Wälchli S, Bai B, Smeland EB, Levy R, Kolstad A, Huse K, Myklebust JH (2019)
TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma
Cancer Immunol Res, 7 (3), 355-362
DOI 10.1158/2326-6066.CIR-18-0351, PubMed 30659053

Kirkhus L, Šaltytė Benth J, Grønberg BH, Hjermstad MJ, Rostoft S, Harneshaug M, Selbæk G, Wyller TB, Jordhøy MS (2019)
Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients: Prospective observational study
Palliat Med, 33 (3), 312-322
DOI 10.1177/0269216319825972, PubMed 30712456

Kryeziu K, Bruun J, Guren TK, Sveen A, Lothe RA (2019)
Combination therapies with HSP90 inhibitors against colorectal cancer
Biochim Biophys Acta Rev Cancer, 1871 (2), 240-247 (in press)
DOI 10.1016/j.bbcan.2019.01.002, PubMed 30708039

Köksal H, Müller E, Inderberg EM, Bruland Ø, Wälchli S (2019)
Treating osteosarcoma with CAR T cells
Scand J Immunol, 89 (3), e12741
DOI 10.1111/sji.12741, PubMed 30549299

Latysheva A, Emblem KE, Brandal P, Vik-Mo EO, Pahnke J, Røysland K, Hald JK, Server A (2019)
Dynamic susceptibility contrast and diffusion MR imaging identify oligodendroglioma as defined by the 2016 WHO classification for brain tumors: histogram analysis approach
Neuroradiology (in press)
DOI 10.1007/s00234-019-02173-5, PubMed 30712139

Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
Integrative genomic analysis of peritoneal malignant mesothelioma: Understanding a case with extraordinary chemotherapy response
Cold Spring Harb Mol Case Stud (in press)
DOI 10.1101/mcs.a003566, PubMed 30862609

Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre MR, Fåne A, Gaudernack G, Kvalheim G, Myklebust JH, Inderberg EM, Wälchli S (2019)
NK cells specifically TCR-dressed to kill cancer cells
EBioMedicine, 40, 106-117
DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853

Mensali N, Grenov A, Pati NB, Dillard P, Myhre MR, Gaudernack G, Kvalheim G, Inderberg EM, Bakke O, Wälchli S (2019)
Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
Oncoimmunology, 8 (3), 1558663
DOI 10.1080/2162402X.2018.1558663, PubMed 30723591

Nyakas M, Aamdal E, Jacobsen KD, Guren TK, Aamdal S, Hagene KT, Brunsvig P, Yndestad A, Halvorsen B, Tasken KA, Aukrust P, Maelandsmo GM, Ueland T (2019)
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Clin Exp Immunol (in press)
DOI 10.1111/cei.13283, PubMed 30821848

Olsen JA, Brunborg C, Steinberg M, Persse D, Sterz F, Lozano M, Westfall M, van Grunsven PM, Lerner EB, Wik L (2019)
Survival to hospital discharge with biphasic fixed 360 joules versus 200 escalating to 360 joules defibrillation strategies in out-of-hospital cardiac arrest of presumed cardiac etiology
Resuscitation, 136, 112-118
DOI 10.1016/j.resuscitation.2019.01.020, PubMed 30708074

Rusten E, Rekstad BL, Undseth C, Klotz D, Hernes E, Guren MG, Malinen E (2019)
Anal cancer chemoradiotherapy outcome prediction using 18F-fluorodeoxyglucose positron emission tomography and clinicopathological factors
Br J Radiol, 20181006 (in press)
DOI 10.1259/bjr.20181006, PubMed 30810343

Röhrl K, Guren MG, Småstuen MC, Rustøen T (2019)
Symptoms during chemotherapy in colorectal cancer patients
Support Care Cancer (in press)
DOI 10.1007/s00520-018-4598-y, PubMed 30607676

Scholz J, Finnerup NB, Attal N, Aziz Q, Baron R, Bennett MI, Benoliel R, Cohen M, Cruccu G, Davis KD, Evers S, First M, Giamberardino MA, Hansson P, Kaasa S, Korwisi B, Kosek E, Lavandʼhomme P, Nicholas M, Nurmikko T, Perrot S, Raja SN, Rice ASC, Rowbotham MC, Schug S et al. (2019)
The IASP classification of chronic pain for ICD-11: chronic neuropathic pain
Pain, 160 (1), 53-59
DOI 10.1097/j.pain.0000000000001365, PubMed 30586071

Shao B, Bjaanæs MM, Helland Å, Schütte C, Conrad T (2019)
EMT network-based feature selection improves prognosis prediction in lung adenocarcinoma
PLoS One, 14 (1), e0204186
DOI 10.1371/journal.pone.0204186, PubMed 30703089

Singer S, Amdal CD, Hammerlid E, Tomaszewska IM, Castro Silva J, Mehanna H, Santos M, Inhestern J, Brannan C, Yarom N, Fullerton A, Pinto M, Arraras JI, Kiyota N, Bonomo P, Sherman AC, Baumann I, Galalae R, Fernandez Gonzalez L, Nicolatou-Galitis O, Abdel-Hafeez Z, Raber-Durlacher J, Schmalz C, Zotti P, Boehm A et al. (2019)
International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV
Head Neck (in press)
DOI 10.1002/hed.25609, PubMed 30636188

Steen CB, Leich E, Myklebust JH, Lockmer S, Wise JF, Wahlin BE, Østenstad B, Liestøl K, Kimby E, Rosenwald A, Smeland EB, Holte H, Lingjærde OC, Brodtkorb M (2019)
A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy
Haematologica (in press)
DOI 10.3324/haematol.2018.209080, PubMed 30846496

Sunde B, Johnsen G, Jacobsen AB, Glenjen NI, Friesland S, Lindblad M, Rouvelas I, Wang N, Lundell L, Lagergren P, Nilsson M (2019)
Effects of neoadjuvant chemoradiotherapy vs chemotherapy alone on the relief of dysphagia in esophageal cancer patients: secondary endpoint analysis in a randomized trial
Dis Esophagus, 32 (2)
DOI 10.1093/dote/doy069, PubMed 30084992

Switlyk MD, Salberg UB, Geier OM, Vlatkovic L, Lilleby W, Lyng H, Seierstad T (2019)
PTEN Expression in Prostate Cancer: Relationship With Clinicopathologic Features and Multiparametric MRI Findings
AJR Am J Roentgenol, 1-9 (in press)
DOI 10.2214/AJR.18.20743, PubMed 30888866

Thorkildsen J, Taksdal I, Bjerkehagen B, Haugland HK, Børge Johannesen T, Viset T, Norum OJ, Bruland Ø, Zaikova O (2019)
Chondrosarcoma in Norway 1990-2013; an epidemiological and prognostic observational study of a complete national cohort
Acta Oncol, 1-10 (in press)
DOI 10.1080/0284186X.2018.1554260, PubMed 30632866

Torper J, Ansteinsson V, Lundeby T (2019)
Moving The Four Habits Model into Dentistry. Development of a Dental Consultation Model Do dentists need an additional habit?
Eur J Dent Educ (in press)
DOI 10.1111/eje.12421, PubMed 30659766

Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Korwisi B, Kosek E, Lavandʼhomme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ (2019)
Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)
Pain, 160 (1), 19-27
DOI 10.1097/j.pain.0000000000001384, PubMed 30586067

Tøndel H, Solberg A, Lydersen S, Jensen CA, Kaasa S, Lund JÅ (2019)
Rectal volume variations and estimated rectal dose during 8 weeks of image-guided radical 3D conformal external beam radiotherapy for prostate cancer
Clin Transl Radiat Oncol, 15, 113-117
DOI 10.1016/j.ctro.2019.02.003, PubMed 30834350

von Döbeln GA, Klevebro F, Jacobsen AB, Johannessen HO, Nielsen NH, Johnsen G, Hatlevoll I, Glenjen NI, Friesland S, Lundell L, Yu J, Nilsson M (2019)
Neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the esophagus or gastroesophageal junction: long-term results of a randomized clinical trial
Dis Esophagus, 32 (2)
DOI 10.1093/dote/doy078, PubMed 30137281

 
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