Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Pediatric Research

32 publications found

Albatat M, Bergsland J, Arevalo H, Odland HH, Wall S, Sundnes J, Balasingham I (2020)
Multisite pacing and myocardial scars: a computational study
Comput Methods Biomech Biomed Engin, 23 (6), 248-260
DOI 10.1080/10255842.2020.1711885, PubMed 31958019

Atneosen-Åsegg M, Melheim M, Almaas R (2020)
MicroRNA in dried blood spots from patients with Aagenaes syndrome and evaluation of pre-analytical and analytical factors
Pediatr Res (in press)
DOI 10.1038/s41390-020-01153-3, PubMed 32932426

Bjørnland K, Hukkinen M, Gatzinsky V, Arnell H, Pakarinen MP, Almaas R, Svensson JF (2020)
Partial Biliary Diversion May Promote Long-Term Relief of Pruritus and Native Liver Survival in Children with Cholestatic Liver Diseases
Eur J Pediatr Surg (in press)
DOI 10.1055/s-0040-1714657, PubMed 32707578

Bratseth V, Margeirsdottir HD, Chiva-Blanch G, Heier M, Solheim S, Arnesen H, Dahl-Jørgensen K, Seljeflot I (2020)
Annexin V+ Microvesicles in Children and Adolescents with Type 1 Diabetes: A Prospective Cohort Study
J Diabetes Res, 2020, 7216863
DOI 10.1155/2020/7216863, PubMed 32309448

Bratseth V, Margeirsdottir HD, Heier M, Solheim S, Arnesen H, Dahl-Jørgensen K, Seljeflot I (2020)
Procoagulant activity in children and adolescents on intensive insulin therapy
Pediatr Diabetes, 21 (3), 496-504
DOI 10.1111/pedi.12978, PubMed 31943582

Brunsvig Jarvis K, Lind A, LeBlanc M, Ruud E (2020)
Observed reduction in the diagnosis of acute lymphoblastic leukaemia in children during the COVID-19 pandemic
Acta Paediatr (in press)
DOI 10.1111/apa.15576, PubMed 32959407

Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP (2020)
Sharing Progress in Neonatology (SPIN): Old Favorites - Bronchopulmonary Dysplasia, Patent Ductus Arteriosus, and Necrotizing Enterocolitis plus Some Global Neonatology and the Future of Clinical Trials
Neonatology, 117 (2), 204-206
DOI 10.1159/000506774, PubMed 32610329

Dypvik J, Saugstad OD, Eskild A (2020)
More Details Needed on Association of Placental Weight With Risk of Neonatal Death-Reply
JAMA Pediatr (in press)
DOI 10.1001/jamapediatrics.2020.0975, PubMed 32453387

Goutaki M, Halbeisen FS, Barbato A, Crowley S, Harris A, Hirst RA, Karadag B, Martinu V, Morgan L, O'Callaghan C, Ozçelik U, Scigliano S, Ucros S, Yiallouros P, Schulzke SM, Kuehni CE (2020)
Late Diagnosis of Infants with PCD and Neonatal Respiratory Distress
J Clin Med, 9 (9)
DOI 10.3390/jcm9092871, PubMed 32899853

Grinde D, Øverland T, Lima K, Schjalm C, Mollnes TE, Abrahamsen TG (2020)
Complement Activation in 22q11.2 Deletion Syndrome
J Clin Immunol, 40 (3), 515-523
DOI 10.1007/s10875-020-00766-x, PubMed 32152940

Gul KA, Strand J, Pettersen RD, Brun H, Abrahamsen TG (2020)
T-cell Receptor Excision Circles in Newborns with Heart Defects
Pediatr Cardiol, 41 (4), 809-815
DOI 10.1007/s00246-020-02317-y, PubMed 32166410

Haflidadottir S, Matthews IL, Almaas R (2020)
Cytokine profile in children with food allergy following liver transplantation
Pediatr Transplant, 24 (2), e13657
DOI 10.1111/petr.13657, PubMed 32067305

Jarvis KB, Nielsen RL, Gupta R, Hede FD, Huttunen P, Jónsson ÓG, Rank CU, Ranta S, Saks K, Trakymiene SS, Tuckuviene R, Tulstrup M, INVENT consortium, Ruud E, Schmiegelow K, LeBlanc M (2020)
Polygenic risk score-analysis of thromboembolism in patients with acute lymphoblastic leukemia
Thromb Res, 196, 15-20 (in press)
DOI 10.1016/j.thromres.2020.08.015, PubMed 32818716

Lande A, Fluge Ø, Strand EB, Flåm ST, Sosa DD, Mella O, Egeland T, Saugstad OD, Lie BA, Viken MK (2020)
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Sci Rep, 10 (1), 5267
DOI 10.1038/s41598-020-62157-x, PubMed 32210306

Liang KX, Kristiansen CK, Mostafavi S, Vatne GH, Zantingh GA, Kianian A, Tzoulis C, Høyland LE, Ziegler M, Perez RM, Furriol J, Zhang Z, Balafkan N, Hong Y, Siller R, Sullivan GJ, Bindoff LA (2020)
Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations
EMBO Mol Med, e12146
DOI 10.15252/emmm.202012146, PubMed 32840960

Lund Håheim L, Schwarze PE, Thelle DS, Nafstad P, Rønningen KS, Olsen I (2020)
Low levels of antibodies for the oral bacterium Tannerella forsythia predict cardiovascular disease mortality in men with myocardial infarction: A prospective cohort study
Med Hypotheses, 138, 109575
DOI 10.1016/j.mehy.2020.109575, PubMed 32088522

Lund-Blix NA, Tapia G, Mårild K, Brantsaeter AL, Njølstad PR, Joner G, Skrivarhaug T, Størdal K, Stene LC (2020)
Maternal and child gluten intake and association with type 1 diabetes: The Norwegian Mother and Child Cohort Study
PLoS Med, 17 (3), e1003032
DOI 10.1371/journal.pmed.1003032, PubMed 32119659

Myrdal OH, Diep PP, Ruud E, Brinch L, Massey RJ, Edvardsen E, Kongerud J, Lund MB, Sikkeland LI (2020)
Determinants of cardiorespiratory fitness in very long-term survivors of allogeneic hematopoietic stem cell transplantation: a national cohort study
Support Care Cancer
DOI 10.1007/s00520-020-05644-1, PubMed 32827056

Saugstad OD (2020)
What did I learn as a neonatologist over 40 years and what impact did Napoleon have on modern newborn medicine?
Acta Paediatr, 109 (5), 877-879
DOI 10.1111/apa.15170, PubMed 31943367

Saugstad OD, Lakshminrusimha S, Vento M (2020)
Optimizing Oxygenation of the Extremely Premature Infant during the First Few Minutes of Life: Start Low or High?
J Pediatr (in press)
DOI 10.1016/j.jpeds.2020.07.034, PubMed 32663594

Skjefstad K, Solberg O, Glosli H, von der Lippe C, Feragen KB (2020)
Life expectancy and cause of death in individuals with haemophilia A and B in Norway, 1986-2018
Eur J Haematol
DOI 10.1111/ejh.13494, PubMed 32710483

Spijkers S, Littooij AS, Kwee TC, Tolboom N, Beishuizen A, Bruin MCA, Elias SG, van de Brug T, Enríquez G, Sábado C, Miller E, Granata C, de Lange C, Verzegnassi F, Greer MC, de Keizer B, Nievelstein RAJ (2020)
Whole-body MRI versus an FDG-PET/CT-based reference standard for staging of paediatric Hodgkin lymphoma: a prospective multicentre study
Eur Radiol
DOI 10.1007/s00330-020-07182-0, PubMed 32880696

Stadskleiv K, Stensvold E, Stokka K, Bechensteen AG, Brandal P (2020)
Neuropsychological functioning in survivors of childhood medulloblastoma/CNS-PNET: The role of secondary medical complications
Clin Neuropsychol
DOI 10.1080/13854046.2020.1794045, PubMed 32729777

Stensvold E, Stadskleiv K, Myklebust TÅ, Wesenberg F, Helseth E, Bechensteen AG, Brandal P (2020)
Unmet rehabilitation needs in 86% of Norwegian paediatric embryonal brain tumour survivors
Acta Paediatr, 109 (9), 1875-1886
DOI 10.1111/apa.15188, PubMed 31977119

Strand J, Gul KA, Erichsen HC, Lundman E, Berge MC, Trømborg AK, Sørgjerd LK, Ytre-Arne M, Hogner S, Halsne R, Gaup HJ, Osnes LT, Kro GAB, Sorte HS, Mørkrid L, Rowe AD, Tangeraas T, Jørgensen JV, Alme C, Bjørndalen TEH, Rønnestad AE, Lang AM, Rootwelt T, Buechner J, Øverland T et al. (2020)
Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency
Front Immunol, 11, 1417
DOI 10.3389/fimmu.2020.01417, PubMed 32754152

Tanaka Y, Cakir B, Xiang Y, Sullivan GJ, Park IH (2020)
Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain
Cell Rep, 30 (6), 1682-1689.e3
DOI 10.1016/j.celrep.2020.01.038, PubMed 32049002

Terwisscha van Scheltinga SEJ, Wijnen MHWA, Martelli H, Rogers T, Mandeville H, Gaze MN, McHugh K, Corradini N, Orbach D, Jenney M, Kelsey A, Chisholm J, Gallego S, Glosli H, Ferrari A, Zanetti I, De Salvo GL, Minard-Colin V, Bisogno G, van Noesel MM, Merks HHM (2020)
Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG-RMS2005 study
Cancer Med
DOI 10.1002/cam4.3365, PubMed 32869534

Thorsteinsdottir H, Christensen JJ, Holven KB, Tveiterås M, Brun H, Åsberg A, Bjerre A (2020)
Cardiovascular Risk Factors are Inversely Associated With Omega-3 Polyunsaturated Fatty Acid Plasma Levels in Pediatric Kidney Transplant Recipients
J Ren Nutr (in press)
DOI 10.1053/j.jrn.2020.06.002, PubMed 32792219

Thorsteinsdottir H, Salvador CL, Mjøen G, Lie A, Sugulle M, Tøndel C, Brun A, Almaas R, Bjerre A (2020)
Growth Differentiation Factor 15 in Children with Chronic Kidney Disease and after Renal Transplantation
Dis Markers, 2020, 6162892
DOI 10.1155/2020/6162892, PubMed 32089755

Tuomilehto J, Ogle GD, Lund-Blix NA, Stene LC (2020)
Update on Worldwide Trends in Occurrence of Childhood Type 1 Diabetes in 2020
Pediatr Endocrinol Rev, 17 (Suppl 1), 198-209
DOI 10.17458/per.vol17.2020.tol.epidemiologychildtype1diabetes, PubMed 32208564

Xiang Y, Tanaka Y, Patterson B, Hwang SM, Hysolli E, Cakir B, Kim KY, Wang W, Kang YJ, Clement EM, Zhong M, Lee SH, Cho YS, Patra P, Sullivan GJ, Weissman SM, Park IH (2020)
Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons
Mol Cell, 79 (1), 84-98.e9
DOI 10.1016/j.molcel.2020.05.016, PubMed 32526163

Zasada M, Madetko-Talowska A, Revhaug C, Rognlien AGW, Baumbusch LO, Książek T, Szewczyk K, Grabowska A, Bik-Multanowski M, Józef Pietrzyk J, Kwinta P, Didrik Saugstad O (2020)
Transcriptome analysis reveals dysregulation of genes involved in oxidative phosphorylation in a murine model of retinopathy of prematurity
Pediatr Res, 88 (3), 391-397
DOI 10.1038/s41390-020-0793-x, PubMed 32053824

 
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