Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2016 from OUS - Department of Pediatric Research

33 publications found

Aresvik DM, Lima K, Øverland T, Mollnes TE, Abrahamsen TG (2016)
Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome
Scand J Immunol, 83 (3), 188-94
DOI 10.1111/sji.12406, PubMed 26708691

Asadi-Azarbaijani B, Santos RR, Jahnukainen K, Braber S, van Duursen MBM, Toppari J, Saugstad OD, Nurmio M, Oskam IC (2016)
Developmental effects of imatinib mesylate on follicle assembly and early activation of primordial follicle pool in postnatal rat ovary
Reprod Biol, 17 (1), 25-33
DOI 10.1016/j.repbio.2016.11.003, PubMed 28040471

Aschner JL, Gien J, Ambalavanan N, Kinsella JP, Konduri GG, Lakshminrusimha S, Saugstad OD, Steinhorn RH (2016)
Challenges, priorities and novel therapies for hypoxemic respiratory failure and pulmonary hypertension in the neonate
J Perinatol, 36 Suppl 2, S32-6
DOI 10.1038/jp.2016.47, PubMed 27225964

Aune D, Sen A, Henriksen T, Saugstad OD, Tonstad S (2016)
Physical activity and the risk of gestational diabetes mellitus: a systematic review and dose-response meta-analysis of epidemiological studies
Eur J Epidemiol, 31 (10), 967-997
DOI 10.1007/s10654-016-0176-0, PubMed 27485519

Benterud T, Ystgaard MB, Manueldas S, Pankratov L, Alfaro-Cervello C, Florholmen G, Ahmed MS, Sandvik L, Norgren S, Bjørås M, Baumbusch LO, Solberg R, Saugstad OD (2016)
N-Acetylcysteine Amide Exerts Possible Neuroprotective Effects in Newborn Pigs after Perinatal Asphyxia
Neonatology, 111 (1), 12-21
DOI 10.1159/000447255, PubMed 27497671

Bryn V, Aass HC, Skjeldal OH, Isaksen J, Saugstad OD, Ormstad H (2016)
Cytokine Profile in Autism Spectrum Disorders in Children
J Mol Neurosci, 61 (1), 1-7
DOI 10.1007/s12031-016-0847-z, PubMed 27730473

Cháfer-Pericás C, Torres-Cuevas I, Sanchez-Illana A, Escobar J, Kuligowski J, Solberg R, Garberg HT, Huun MU, Saugstad OD, Vento M (2016)
Development of a reliable analytical method to determine lipid peroxidation biomarkers in newborn plasma samples
Talanta, 153, 152-7
DOI 10.1016/j.talanta.2016.03.010, PubMed 27130102

Demeulemeester J, Kumar P, Møller EK, Nord S, Wedge DC, Peterson A, Mathiesen RR, Fjelldal R, Zamani Esteki M, Theunis K, Fernandez Gallardo E, Grundstad AJ, Borgen E, Baumbusch LO, Børresen-Dale AL, White KP, Kristensen VN, Van Loo P, Voet T, Naume B (2016)
Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
Genome Biol, 17 (1), 250
DOI 10.1186/s13059-016-1109-7, PubMed 27931250

Escobar J, Sánchez-Illana Á, Kuligowski J, Torres-Cuevas I, Solberg R, Garberg HT, Huun MU, Saugstad OD, Vento M, Cháfer-Pericás C (2016)
Development of a reliable method based on ultra-performance liquid chromatography coupled to tandem mass spectrometry to measure thiol-associated oxidative stress in whole blood samples
J Pharm Biomed Anal, 123, 104-12
DOI 10.1016/j.jpba.2016.02.007, PubMed 26895495

Garberg HT, Huun MU, Baumbusch LO, Åsegg-Atneosen M, Solberg R, Saugstad OD (2016)
Temporal Profile of Circulating microRNAs after Global Hypoxia-Ischemia in Newborn Piglets
Neonatology, 111 (2), 133-139
DOI 10.1159/000449032, PubMed 27750254

Garberg HT, Huun MU, Escobar J, Martinez-Orgado J, Løberg EM, Solberg R, Didrik Saugstad O (2016)
Short-term effects of cannabidiol after global hypoxia-ischemia in newborn piglets
Pediatr Res, 80 (5), 710-718
DOI 10.1038/pr.2016.149, PubMed 27441365

Grytten J, Monkerud L, Skau I, Eskild A, Sørensen RJ, Saugstad OD (2016)
Saving Newborn Babies - The Benefits of Interventions in Neonatal Care in Norway over More Than 40 Years
Health Econ, 26 (3), 352-370
DOI 10.1002/hec.3314, PubMed 26842217

Jørgenrud B, Stene LC, Tapia G, Bøås H, Pepaj M, Berg JP, Thorsby PM, Orešič M, Hyötyläinen T, Rønningen KS (2016)
Longitudinal plasma metabolic profiles, infant feeding, and islet autoimmunity in the MIDIA study
Pediatr Diabetes, 18 (2), 111-119
DOI 10.1111/pedi.12360, PubMed 26791677

Kaveh F, Baumbusch LO, Nebdal D, Børresen-Dale AL, Lingjærde OC, Edvardsen H, Kristensen VN, Solvang HK (2016)
A systematic comparison of copy number alterations in four types of female cancer
BMC Cancer, 16 (1), 913
DOI 10.1186/s12885-016-2899-4, PubMed 27876019

Lakshminrusimha S, Saugstad OD (2016)
The fetal circulation, pathophysiology of hypoxemic respiratory failure and pulmonary hypertension in neonates, and the role of oxygen therapy
J Perinatol, 36 Suppl 2, S3-S11
DOI 10.1038/jp.2016.43, PubMed 27225963

Levinsen M, Marquart HV, Groth-Pedersen L, Abrahamsson J, Albertsen BK, Andersen MK, Frandsen TL, Harila-Saari A, Pronk C, Ulvmoen A, Vaitkevičienė G, Lähteenmäki PM, Niinimäki R, Taskinen M, Jeppesen M, Schmiegelow K, Nordic Society of Pediatric Hematology and Oncology (NOPHO) (2016)
Leukemic blasts are present at low levels in spinal fluid in one-third of childhood acute lymphoblastic leukemia cases
Pediatr Blood Cancer, 63 (11), 1935-42
DOI 10.1002/pbc.26128, PubMed 27447373

Littooij AS, Kwee TC, Enríquez G, Verbeke JI, Granata C, Beishuizen A, de Lange C, Zennaro F, Bruin MC, Nievelstein RA (2016)
Whole-body MRI reveals high incidence of osteonecrosis in children treated for Hodgkin lymphoma
Br J Haematol, 176 (4), 637-642
DOI 10.1111/bjh.14452, PubMed 27891588

Lund-Blix NA, Rønningen KS, Bøås H, Tapia G, Andersen LF (2016)
Plasma phospholipid pentadecanoic acid, EPA, and DHA, and the frequency of dairy and fish product intake in young children
Food Nutr Res, 60, 31933
DOI 10.3402/fnr.v60.31933, PubMed 27534845

Lundman E, Gaup HJ, Bakkeheim E, Olafsdottir EJ, Rootwelt T, Storrøsten OT, Pettersen RD (2016)
Implementation of newborn screening for cystic fibrosis in Norway. Results from the first three years
J Cyst Fibros, 15 (3), 318-24
DOI 10.1016/j.jcf.2015.12.017, PubMed 26795017

Manja V, Saugstad OD, Lakshminrusimha S (2016)
Oxygen Saturation Targets in Preterm Infants and Outcomes at 18-24 Months: A Systematic Review
Pediatrics, 139 (1)
DOI 10.1542/peds.2016-1609, PubMed 27940510

Mathapati S, Siller R, Impellizzeri AA, Lycke M, Vegheim K, Almaas R, Sullivan GJ (2016)
Small-Molecule-Directed Hepatocyte-Like Cell Differentiation of Human Pluripotent Stem Cells
Curr Protoc Stem Cell Biol, 38, 1G.6.1-1G.6.18
DOI 10.1002/cpsc.13, PubMed 27532814

Oei JL, Ghadge A, Coates E, Wright IM, Saugstad OD, Vento M, Buonocore G, Nagashima T, Suzuki K, Hosono S, Davis PG, Craven P, Askie L, Dawson J, Garg S, Keech A, Rabi Y, Smyth J, Sinha S, Stenson B, Lui K, Hunter CL, Tarnow Mordi W, HOLISTIC (Higher Or Lower oxygen and Infant Saturation Targeting: International Collaboration) Study Group (2016)
Clinicians in 25 countries prefer to use lower levels of oxygen to resuscitate preterm infants at birth
Acta Paediatr, 105 (9), 1061-6
DOI 10.1111/apa.13485, PubMed 27228325

Oei JL, Vento M, Rabi Y, Wright I, Finer N, Rich W, Kapadia V, Aune D, Rook D, Tarnow-Mordi W, Saugstad OD (2016)
Higher or lower oxygen for delivery room resuscitation of preterm infants below 28 completed weeks gestation: a meta-analysis
Arch Dis Child Fetal Neonatal Ed, 102 (1), F24-F30
DOI 10.1136/archdischild-2016-310435, PubMed 27150977

Panagopoulos I, Torkildsen S, Gorunova L, Ulvmoen A, Tierens A, Zeller B, Heim S (2016)
RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Oncol Rep, 36 (5), 2481-2488
DOI 10.3892/or.2016.5119, PubMed 27667292

Pettersen FJ, Martinsen OG, Hogetveit JO, Kalvoy H, Odland HH (2016)
Bioimpedance measurements of temporal changes in beating hearts
Biomed. Phys. Eng. Express, 2 (6), UNSP 065015

Richardson SJ, Rodriguez-Calvo T, Gerling IC, Mathews CE, Kaddis JS, Russell MA, Zeissler M, Leete P, Krogvold L, Dahl-Jørgensen K, von Herrath M, Pugliese A, Atkinson MA, Morgan NG (2016)
Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes
Diabetologia, 59 (11), 2448-2458
DOI 10.1007/s00125-016-4067-4, PubMed 27506584

Rognlien AG, Wollen EJ, Atneosen-Åsegg M, Saugstad OD (2016)
Temporal Patterns of Gene Expression Profiles in the Neonatal Mouse Lung after Hypoxia-Reoxygenation
Neonatology, 111 (1), 45-54
DOI 10.1159/000447322, PubMed 27529351

Rognum TO, Holmen S, Musse MA, Dahlberg PS, Stray-Pedersen A, Saugstad OD, Opdal SH (2016)
Estimation of time since death by vitreous humor hypoxanthine, potassium, and ambient temperature
Forensic Sci Int, 262, 160-5
DOI 10.1016/j.forsciint.2016.03.001, PubMed 26994446

Singleton R, Holman RC (2016)
Hospitalizations with Lower Respiratory Tract Infections among American Indian and Alaska Native Children Under Age 5 Years: The Use of Non-Federal Hospital Discharge Data to Analyze Rates
J Pediatr, 175, 10-2
DOI 10.1016/j.jpeds.2016.05.001, PubMed 27233522

Solberg R, Kuligowski J, Pankratov L, Escobar J, Quintás G, Lliso I, Sánchez-Illana Á, Saugstad OD, Vento M (2016)
Changes of the plasma metabolome of newly born piglets subjected to postnatal hypoxia and resuscitation with air
Pediatr Res, 80 (2), 284-92
DOI 10.1038/pr.2016.66, PubMed 27055187

Sorte HS, Osnes LT, Fevang B, Aukrust P, Erichsen HC, Backe PH, Abrahamsen TG, Kittang OB, Øverland T, Jhangiani SN, Muzny DM, Vigeland MD, Samarakoon P, Gambin T, Akdemir ZH, Gibbs RA, Rødningen OK, Lyle R, Lupski JR, Stray-Pedersen A (2016)
A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction
Mol Genet Genomic Med, 4 (6), 604-616
DOI 10.1002/mgg3.237, PubMed 27896283

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Vento M, Visser GH, Halliday HL (2016)
European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2016 Update
Neonatology, 111 (2), 107-125
DOI 10.1159/000448985, PubMed 27649091

Torres-Cuevas I, Kuligowski J, Cárcel M, Cháfer-Pericás C, Asensi M, Solberg R, Cubells E, Nuñez A, Saugstad OD, Vento M, Escobar J (2016)
Protein-bound tyrosine oxidation, nitration and chlorination by-products assessed by ultraperformance liquid chromatography coupled to tandem mass spectrometry
Anal Chim Acta, 913, 104-10
DOI 10.1016/j.aca.2016.01.054, PubMed 26944994

 
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