Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2017 from OUS - Department of Paediatric Medicine
65 publications found
Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes
J Allergy Clin Immunol, 139 (2), 388-399
DOI 10.1016/j.jaci.2016.12.940, PubMed 28183433
Renal failure of systemic vasculitis in children
Tidsskr. Nor. Laegeforen., 137 (19), 1507-1511
Renal involvement in paediatric systemic vasculitis
Tidsskr Nor Laegeforen, 137 (19)
DOI 10.4045/tidsskr.16.0592, PubMed 29043736
LEFT-VENTRICLE TO CORONARY VENOUS TREE 3D FUSION FOR CARDIAC RESYNCHRONIZATION THERAPY APPLICATIONS
2017 IEEE 14TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2017), 164-168
High-resolution data assimilation of cardiac mechanics applied to a dyssynchronous ventricle
Int J Numer Method Biomed Eng, 33 (11)
DOI 10.1002/cnm.2863, PubMed 28039961
Symptoms and Mucosal Changes Stable During Rapid Increase of Pediatric Celiac Disease in Norway
J Pediatr Gastroenterol Nutr, 64 (4), 586-591
DOI 10.1097/MPG.0000000000001307, PubMed 27299421
Weight-for-length, early weight-gain velocity and atopic dermatitis in infancy and at two years of age: a cohort study
BMC Pediatr, 17 (1), 141
DOI 10.1186/s12887-017-0889-6, PubMed 28592289
Incidence of severe hypoglycemia in children with type 1 diabetes in the Nordic countries in the period 2008-2012: association with hemoglobin A 1c and treatment modality
BMJ Open Diabetes Res Care, 5 (1), e000377
DOI 10.1136/bmjdrc-2016-000377, PubMed 28761652
Liver diseases in Adult Life after Childhood Cancer in Scandinavia (ALiCCS): A population-based cohort study of 32,839 one-year survivors
Int J Cancer, 142 (4), 702-708
DOI 10.1002/ijc.31093, PubMed 29023764
Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA
J Nutr Health Aging, 21 (1), 92-104
DOI 10.1007/s12603-016-0803-1, PubMed 27999855
Long-time sickness absence among parents of pre-school children with cerebral palsy, spina bifida and down syndrome: a longitudinal study
BMC Pediatr, 17 (1), 26
DOI 10.1186/s12887-016-0774-8, PubMed 28100193
Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision
J Allergy Clin Immunol, 140 (4), 950-958
DOI 10.1016/j.jaci.2017.03.050, PubMed 28602936
Advanced glycation end products in children with type 1 diabetes and early reduced diastolic heart function
BMC Cardiovasc Disord, 17 (1), 133
DOI 10.1186/s12872-017-0551-0, PubMed 28545398
Mortality risk disparities in children receiving chronic renal replacement therapy for the treatment of end-stage renal disease across Europe: an ESPN-ERA/EDTA registry analysis
Lancet, 389 (10084), 2128-2137
DOI 10.1016/S0140-6736(17)30063-6, PubMed 28336050
Thymus transplantation for complete DiGeorge syndrome: European experience
J Allergy Clin Immunol, 140 (6), 1660-1670.e16
DOI 10.1016/j.jaci.2017.03.020, PubMed 28400115
Long-term inpatient disease burden in the Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study: A cohort study of 21,297 childhood cancer survivors
PLoS Med, 14 (5), e1002296
DOI 10.1371/journal.pmed.1002296, PubMed 28486495
Hepatotoxicity During Maintenance Therapy and Prognosis in Children With Acute Lymphoblastic Leukemia
J Pediatr Hematol Oncol, 39 (3), 161-166
DOI 10.1097/MPH.0000000000000733, PubMed 28060115
Adults with 22q11.2 deletion syndrome have a different velopharyngeal anatomy with predisposition to velopharyngeal insufficiency
J Plast Reconstr Aesthet Surg, 71 (4), 524-536
DOI 10.1016/j.bjps.2017.09.006, PubMed 29032918
Low Incidence of End-Stage Renal Disease in Childhood-Onset Type 1 Diabetes Followed for Up to 42 Years
Diabetes Care, 41 (3), 420-425
DOI 10.2337/dc17-0906, PubMed 29025877
Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10
BMC Immunol, 18 (1), 46
DOI 10.1186/s12865-017-0229-5, PubMed 29078758
Growth and nutritional status, and their association with lung function: a study from the international Primary Ciliary Dyskinesia Cohort
Eur Respir J, 50 (6)
DOI 10.1183/13993003.01659-2017, PubMed 29269581
The international primary ciliary dyskinesia cohort (iPCD Cohort): methods and first results
Eur Respir J, 49 (1)
DOI 10.1183/13993003.01181-2016, PubMed 28052956
Depression-A Major Contributor to Poor Quality of Life in Patients With Advanced Cancer
J Pain Symptom Manage, 54 (6), 889-897
DOI 10.1016/j.jpainsymman.2017.04.010, PubMed 28803091
Thymus activity measured by T-cell receptor excision circles in patients with different severities of respiratory syncytial virus infection
BMC Infect Dis, 17 (1), 18
DOI 10.1186/s12879-016-2148-0, PubMed 28056841
When an underage patient refuses life saving treatment
Tidsskr. Nor. Laegeforen., 137 (14-15), 1072-1074
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis
J Intensive Care, 5, 21
DOI 10.1186/s40560-017-0217-0, PubMed 28261486
Use of Laboratory Markers in Addition to Symptoms for Diagnosis of Inflammatory Bowel Disease in Children: A Meta-analysis of Individual Patient Data
JAMA Pediatr, 171 (10), 984-991
DOI 10.1001/jamapediatrics.2017.1736, PubMed 28806445
The clinical use of mechanical insufflation-exsufflation in children with neuromuscular disorders in Europe
Paediatr Respir Rev, 27, 69-73
DOI 10.1016/j.prrv.2017.08.003, PubMed 29239774
Prenatal exposure to perfluoralkyl substances (PFASs) associated with respiratory tract infections but not allergy- and asthma-related health outcomes in childhood
Environ Res, 160, 518-523
DOI 10.1016/j.envres.2017.10.012, PubMed 29106950
Out-of-hospital sudden cardiac arrest in children with congenital heart defects
Arch Dis Child, 103 (1), 57-60
DOI 10.1136/archdischild-2017-312621, PubMed 28838970
Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia
Mol Med Rep, 15 (4), 1513-1526
DOI 10.3892/mmr.2017.6185, PubMed 28259955
Outcome after intensive reinduction therapy and allogeneic stem cell transplant in paediatric relapsed acute myeloid leukaemia
Br J Haematol, 178 (4), 592-602
DOI 10.1111/bjh.14720, PubMed 28439893
Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting
PLoS One, 12 (11), e0187618
DOI 10.1371/journal.pone.0187618, PubMed 29112974
Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations
Hum Mol Genet, 26 (9), 1716-1731
DOI 10.1093/hmg/ddx086, PubMed 28334964
Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes
Am J Pathol, 187 (3), 581-588
DOI 10.1016/j.ajpath.2016.11.002, PubMed 28212742
Busulfan and melphalan versus carboplatin, etoposide, and melphalan as high-dose chemotherapy for high-risk neuroblastoma (HR-NBL1/SIOPEN): an international, randomised, multi-arm, open-label, phase 3 trial
Lancet Oncol, 18 (4), 500-514
DOI 10.1016/S1470-2045(17)30070-0, PubMed 28259608
Experiences with late effects-related care and preferences for long-term follow-up care among adult survivors of childhood lymphoma
Support Care Cancer, 25 (8), 2445-2454
DOI 10.1007/s00520-017-3651-6, PubMed 28236146
Conjunctival provocation test in diagnosis of peanut allergy in children
Clin Exp Allergy, 47 (6), 785-794
DOI 10.1111/cea.12899, PubMed 28160326
Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts
Diabetes Care, 40 (7), 920-927
DOI 10.2337/dc17-0016, PubMed 28487451
The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes
PLoS One, 12 (6), e0179911
DOI 10.1371/journal.pone.0179911, PubMed 28628651
An immunohistochemical study of nitrotyrosine expression in pancreatic islets of cases with increasing duration of type 1 diabetes and without diabetes
Histochem Cell Biol, 147 (5), 605-623
DOI 10.1007/s00418-016-1533-5, PubMed 28154952
Do negative emotions expressed during follow-up consultations with adolescent survivors of childhood cancer reflect late effects?
Patient Educ Couns, 100 (11), 2098-2101
DOI 10.1016/j.pec.2017.06.008, PubMed 28641990
An intronic variation in SLC52A1 causes exon skipping and transient riboflavin-responsive multiple acyl-CoA dehydrogenation deficiency
Mol Genet Metab, 122 (4), 182-188
DOI 10.1016/j.ymgme.2017.10.014, PubMed 29122468
Protracted bacterial bronchitis in children
Tidsskr. Nor. Laegeforen., 137 (14-15), 1043-1046
Verona Coding Definitions of Emotional Sequences (VR-CoDES): Conceptual framework and future directions
Patient Educ Couns, 100 (12), 2303-2311
DOI 10.1016/j.pec.2017.06.026, PubMed 28673489
Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset
Diabetes, 66 (5), 1334-1345
DOI 10.2337/db16-1343, PubMed 28137793
Morning Salivary Cortisol in Young Children: Reference Values and the Effects of Age, Sex, and Acute Bronchiolitis
J Pediatr, 184, 193-198.e3
DOI 10.1016/j.jpeds.2017.01.064, PubMed 28284475
Renal Function Influences Diagnostic Markers in Serum and Urine: A Study of Guanidinoacetate, Creatine, Human Epididymis Protein 4, and Neutrophil Gelatinase-Associated Lipocalin in Children
J. Appl. Lab. Med., 2 (3), 297-308
Sham surgery versus labral repair or biceps tenodesis for type II SLAP lesions of the shoulder: a three-armed randomised clinical trial
Br J Sports Med, 51 (24), 1759-1766
DOI 10.1136/bjsports-2016-097098, PubMed 28495804
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
Hum Mol Genet, 26 (20), 4067-4085
DOI 10.1093/hmg/ddx290, PubMed 29016858
Prednisolone and Prednisone Pharmacokinetics in Pediatric Renal Transplant Recipients-A Prospective Study
Ther Drug Monit, 39 (5), 472-482
DOI 10.1097/FTD.0000000000000439, PubMed 28749817
Outcome for children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor (CNS-PNET) - a retrospective analysis spanning 40 years of treatment
Acta Oncol, 56 (5), 698-705
DOI 10.1080/0284186X.2017.1301679, PubMed 28325133
Strictly controlled glucose infusion rates are associated with a reduced risk of hyperglycaemia in extremely low birth weight preterm infants
Acta Paediatr, 107 (3), 442-449
DOI 10.1111/apa.14164, PubMed 29172239
Computer-based video analysis identifies infants with absence of fidgety movements
Pediatr Res, 82 (4), 665-670
DOI 10.1038/pr.2017.121, PubMed 28745715
Extramedullary leukemia in children with acute myeloid leukemia: A population-based cohort study from the Nordic Society of Pediatric Hematology and Oncology (NOPHO)
Pediatr Blood Cancer, 64 (12)
DOI 10.1002/pbc.26520, PubMed 28333413
Maternal serum calcitriol during pregnancy and risk of childhood onset type 1 diabetes
Acta Diabetol, 54 (12), 1143-1145
DOI 10.1007/s00592-017-1045-3, PubMed 28875306
Iodine Status and Growth In 0-2-Year-Old Infants With Cow's Milk Protein Allergy
J Pediatr Gastroenterol Nutr, 64 (5), 806-811
DOI 10.1097/MPG.0000000000001434, PubMed 27741063
[Renovascular disease in children - a rare diagnosis with few symptoms]
Tidsskr Nor Laegeforen, 137 (4), 279-282
DOI 10.4045/tidsskr.16.0156, PubMed 28225234
Iohexol plasma clearance in children: validation of multiple formulas and single-point sampling times
Pediatr Nephrol, 33 (4), 683-696
DOI 10.1007/s00467-017-3841-y, PubMed 29134449
HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease
HLA, 89 (5), 278-284
DOI 10.1111/tan.12986, PubMed 28247576
Plasma immunological markers in pregnancy and cord blood: A possible link between macrophage chemo-attractants and risk of childhood type 1 diabetes
Am J Reprod Immunol, 79 (3)
DOI 10.1111/aji.12802, PubMed 29266506
Prognostic relevance of early radiologic response to induction chemotherapy in pediatric rhabdomyosarcoma: A report from the International Society of Pediatric Oncology Malignant Mesenchymal Tumor 95 study
Cancer, 124 (5), 1016-1024
DOI 10.1002/cncr.31157, PubMed 29211298
Eating patterns in adolescents with type 1 diabetes: Associations with metabolic control, insulin omission, and eating disorder pathology
Appetite, 114, 226-231
DOI 10.1016/j.appet.2017.03.035, PubMed 28351671
Hyperleucocytosis in paediatric acute myeloid leukaemia - the challenge of white blood cell counts above 200 × 109 /l. The NOPHO experience 1984-2014
Br J Haematol, 178 (3), 448-456
DOI 10.1111/bjh.14692, PubMed 28542715
No effect of treatment with intravenous ganciclovir on Epstein-Barr virus viremia demonstrated after pediatric liver transplantation
Pediatr Transplant, 21 (6)
DOI 10.1111/petr.13010, PubMed 28653462