Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Neurology

23 publications found

Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, Leonard HL, Grenn FP, Ruskey JA, Sabir M, Ahmed S, Makarious MB, Pihlstrøm L, Toft M, van Hilten JJ, Marinus J et al. (2020)
Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia
Brain, 143 (1), 234-248
DOI 10.1093/brain/awz350, PubMed 31755958

Børte S, Zwart JA, Skogholt AH, Gabrielsen ME, Thomas LF, Fritsche LG, Surakka I, Nielsen JB, Zhou W, Wolford BN, Vigeland MD, Hagen K, Kristoffersen ES, Nyholt DR, Chasman DI, Brumpton BM, Willer CJ, Winsvold BS (2020)
Mitochondrial genome-wide association study of migraine - the HUNT Study
Cephalalgia, 0333102420906835
DOI 10.1177/0333102420906835, PubMed 32056457

Eikeland R, Ljøstad U, Helgeland G, Sand G, Flemmen HØ, Bø MH, Nordaa L, Owe JF, Mygland Å, Lorentzen ÅR (2020)
Patient-reported outcome after treatment for definite Lyme neuroborreliosis
Brain Behav, e01595 (in press)
DOI 10.1002/brb3.1595, PubMed 32153118

Fazio P, Fitzer-Attas CJ, Mrzljak L, Bronzova J, Nag S, Warner JH, Landwehrmeyer B, Al-Tawil N, Halldin C, Forsberg A, Ware J, Dilda V, Wood A, Sampaio C, Varrone A, Svenningsson P, Paucar M, Sundblom J, Nyholm D, Widner H, Heiberg A, Frich J, Nielsen J, Hjermind L, Roos R et al. (2020)
PET molecular imaging of phosphodiesterase 10A: An early biomarker of Huntington's disease progression
Mov. Disord.

González A, Nome CG, Bendiksen BA, Sjaastad I, Zhang L, Aleksandersen M, Taubøll E, Aurlien D, Heuser K (2020)
Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy
Epilepsy Res, 161, 106300
DOI 10.1016/j.eplepsyres.2020.106300, PubMed 32126491

Hamre C, Fure B, Helbostad JL, Wyller TB, Ihle-Hansen H, Vlachos G, Ursin M, Tangen GG (2020)
Balance and Gait After First Minor Ischemic Stroke in People 70 Years of Age or Younger: A Prospective Observational Cohort Study
Phys Ther (in press)
DOI 10.1093/ptj/pzaa010, PubMed 31944247

Hazen J, Vistnes M, Barca ML, Eldholm RS, Persson K, Brækhus A, Saltvedt I, Selbæk G, Engedal K, Knapskog AB (2020)
The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia
Alzheimer Dis Assoc Disord, 34 (1), 47-53
DOI 10.1097/WAD.0000000000000342, PubMed 31414991

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2020)
Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 52 (3), 354
DOI 10.1038/s41588-019-0573-x, PubMed 32029921

Kramer V, Brooks AF, Haeger A, Kuljis RO, Rafique W, Koeppe RA, Raffel DM, Frey KA, Amaral H, Scott PJH, Riss PJ (2020)
Evaluation of [18F]-N-Methyl lansoprazole as a Tau PET Imaging Agent in First-in-Human Studies
ACS Chem Neurosci, 11 (3), 427-435
DOI 10.1021/acschemneuro.9b00639, PubMed 31898886

Krohn L, Wu RYJ, Heilbron K, Ruskey JA, Laurent SB, Blauwendraat C, Alam A, Arnulf I, Hu MTM, Dauvilliers Y, Högl B, Toft M, Bjørnarå KA, Stefani A, Holzknecht E, Monaca CC, Abril B, Plazzi G, Antelmi E, Ferini-Strambi L, Young P, Heidbreder A, Cochen De Cock V, Mollenhauer B, Sixel-Döring F et al. (2020)
Fine-Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies
Ann Neurol, 87 (4), 584-598
DOI 10.1002/ana.25687, PubMed 31976583

Kubach J, Muhlebner-Fahrngruber A, Soylemezoglu F, Miyata H, Niehusmann P, Honavar M, Rogerio F, Kim SH, Aronica E, Garbelli R, Vilz S, Popp A, Walcher S, Neuner C, Scholz M, Kuerten S, Schropp V, Roeder S, Eichhorn P, Eckstein M, Brehmer A, Kobow K, Coras R, Blumcke I, Jabari S (2020)
Same same but different: A Web-based deep learning application revealed classifying features for the histopathologic distinction of cortical malformations
Epilepsia, 61 (3), 421-432
DOI 10.1111/epi.16447, PubMed 32080846

Lao YE, Molden E, Kringen MK, Annexstad EJ, Saeverud HA, Jacobsen D, Hovda KE (2020)
Fatal liver failure after therapeutic doses of paracetamol in a patient with Duchenne muscular dystrophy and atypical pharmacogenetic profile of drug-metabolizing enzymes
Basic Clin Pharmacol Toxicol
DOI 10.1111/bcpt.13389, PubMed 31977139

Luger S, Jæger HS, Dixon J, Bohmann FO, Schaefer J, Richieri SP, Larsen K, Hov MR, Bache KG, Foerch C, BE FAST III Study Group (2020)
Diagnostic Accuracy of Glial Fibrillary Acidic Protein and Ubiquitin Carboxy-Terminal Hydrolase-L1 Serum Concentrations for Differentiating Acute Intracerebral Hemorrhage from Ischemic Stroke
Neurocrit Care
DOI 10.1007/s12028-020-00931-5, PubMed 32096121

Malhotra K, Goyal N, Katsanos AH, Filippatou A, Mistry EA, Khatri P, Anadani M, Spiotta AM, Sandset EC, Sarraj A, Magoufis G, Krogias C, Tönges L, Safouris A, Elijovich L, Goyal M, Arthur A, Alexandrov AV, Tsivgoulis G (2020)
Association of Blood Pressure With Outcomes in Acute Stroke Thrombectomy
Hypertension, 75 (3), 730-739
DOI 10.1161/HYPERTENSIONAHA.119.14230, PubMed 31928111

Najafi J, Brembu T, Vie AK, Viste R, Winge P, Somssich IE, Bones AM (2020)
PAMP-INDUCED SECRETED PEPTIDE 3 modulates immunity in Arabidopsis
J Exp Bot, 71 (3), 850-864
DOI 10.1093/jxb/erz482, PubMed 31665431

Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
Resuscitation, 149, 170-179
DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258

Nome T, Herrman H, Lehtimäki K, Egge A, Konglund A, Ramm-Pettersen J, Taubøll E, Dietrichs E (2020)
Direct visual targeting versus preset coordinates for ANT-DBS in epilepsy
Acta Neurol Scand
DOI 10.1111/ane.13233, PubMed 32078161

Nordengen K, Morland C, Slusher BS, Gundersen V (2020)
Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus
Cereb Cortex, 30 (3), 1422-1435
DOI 10.1093/cercor/bhz176, PubMed 31504271

Simonsen CS, Flemmen HØ, Lauritzen T, Berg-Hansen P, Moen SM, Celius EG (2020)
The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis
Mult Scler J Exp Transl Clin, 6 (1), 2055217319901291
DOI 10.1177/2055217319901291, PubMed 32030196

Smeland OB, Shadrin A, Bahrami S, Broce I, Tesli M, Frei O, Wirgenes KV, O'Connell KS, Krull F, Bettella F, Steen NE, Sugrue L, Wang Y, Svenningsson P, Sharma M, Pihlstrøm L, Toft M, O'Donovan M, Djurovic S, Desikan R, Dale AM, Andreassen OA (2020)
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043

Tancin Lambert A, Kong XY, Ratajczak-Tretel B, Atar D, Russell D, Skjelland M, Bjerkeli V, Skagen K, Coq M, Schordan E, Firat H, Halvorsen B, Aamodt AH (2020)
Biomarkers Associated with Atrial Fibrillation in Patients with Ischemic Stroke: A Pilot Study from the NOR-FIB Study
Cerebrovasc Dis Extra, 10 (1), 11-20 (in press)
DOI 10.1159/000504529, PubMed 32028277

Voldsbekk I, Maximov II, Zak N, Roelfs D, Geier O, Due-Tønnessen P, Elvsåshagen T, Strømstad M, Bjørnerud A, Groote I (2020)
Evidence for wakefulness-related changes to extracellular space in human brain white matter from diffusion-weighted MRI
Neuroimage, 212, 116682 (in press)
DOI 10.1016/j.neuroimage.2020.116682, PubMed 32114147

Zamani M, Skagen K, Scott H, Russell D, Skjelland M (2020)
Advanced ultrasound methods in assessment of carotid plaque instability: a prospective multimodal study
BMC Neurol, 20 (1), 39
DOI 10.1186/s12883-020-1620-z, PubMed 31996153

 
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