Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Plastic and Reconstructive Surgery

23 publications found

Aqrawi LA, Galtung HK, Guerreiro EM, Øvstebø R, Thiede B, Utheim TP, Chen X, Utheim ØA, Palm Ø, Skarstein K, Jensen JL (2019)
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Arthritis Res Ther, 21 (1), 181
DOI 10.1186/s13075-019-1961-4, PubMed 31366407

Botten N, Hodges RR, Li D, Bair JA, Shatos MA, Utheim TP, Serhan CN, Dartt DA (2019)
Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells
FASEB J, 33 (7), 8468-8478
DOI 10.1096/fj.201802467R, PubMed 31013438

Flem-Karlsen K, McFadden E, Omar N, Haugen MH, Øy GF, Ryder T, Gullestad HP, Hermann R, Mælandsmo GM, Flørenes VA (2019)
Targeting AXL and the DNA damage response pathway as a novel therapeutic strategy in melanoma
Mol Cancer Ther (in press)
DOI 10.1158/1535-7163.MCT-19-0290, PubMed 31871265

Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM (2019)
A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
Transl Oncol, 12 (7), 951-958
DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111

Frich L, Bjorkedal BT, Gagama R, Andersson H (2019)
A young woman with white fingers and shortness of breath
Tidsskr. Nor. Laegeforen., 139 (1), 58-62

Impieri D, Tønseth KA, Hide Ø, Feragen KJB, Høgevold HE, Filip C (2019)
Autologous fat transplantation to the velopharynx for treating mild velopharyngeal insufficiency: A 10-year experience
J Plast Reconstr Aesthet Surg, 72 (8), 1403-1410
DOI 10.1016/j.bjps.2019.03.040, PubMed 31103609

Jackson CJ, Myklebust Ernø IT, Ringstad H, Tønseth KA, Dartt DA, Utheim TP (2019)
Simple limbal epithelial transplantation: Current status and future perspectives
Stem Cells Transl Med, 9 (3), 316-327
DOI 10.1002/sctm.19-0203, PubMed 31802651

Mandal E, Filip C, Andersson ME, Øgaard B (2019)
Eighteen-Year Follow-Up of 160 Consecutive Individuals Born With Unilateral Cleft Lip or Cleft Lip and Alveolus Treated by the Oslo Cleft Lip and Palate Team
Cleft Palate Craniofac J, 56 (7), 853-859
DOI 10.1177/1055665618820753, PubMed 30686058

Martinsen T, Pettersen FJ, Kalvøy H, Tronstad C, Kvarstein G, Bakken A, Høgetveit JO, Martinsen ØG, Grimnes S, Frich L (2019)
Electrosurgery and Temperature Increase in Tissue With a Passive Metal Implant
Front Surg, 6, 8
DOI 10.3389/fsurg.2019.00008, PubMed 30915337

Menchini RJ, Chaudhry FA (2019)
Multifaceted regulation of the system A transporter Slc38a2 suggests nanoscale regulation of amino acid metabolism and cellular signaling
Neuropharmacology, 161, 107789
DOI 10.1016/j.neuropharm.2019.107789, PubMed 31574264

Qureshi T, Sørensen C, Berghuis P, Jensen V, Dobszay MB, Farkas T, Dalen KT, Guo C, Hassel B, Utheim TP, Hvalby Ø, Hafting T, Harkany T, Fyhn M, Chaudhry FA (2019)
The Glutamine Transporter Slc38a1 Regulates GABAergic Neurotransmission and Synaptic Plasticity
Cereb Cortex, 29 (12), 5166-5179
DOI 10.1093/cercor/bhz055, PubMed 31050701

Secerbegovic A, Mesic H, Bergsland J, Balasingham I (2019)
Contactless blood perfusion assessment of the free flap in breast reconstruction surgery
INT SYM MED INFORM, 233-236

Skraastad BK, Knudsen C, Jackson C, Utheim TP, Pripp AH, Tønseth KA (2019)
Quality of life, patient satisfaction and cosmetic outcome after delayed breast reconstruction using DIEP flap: a 10 years' follow-up survey
J Plast Surg Hand Surg, 53 (2), 119-124
DOI 10.1080/2000656X.2018.1562459, PubMed 30654667

Stadnikova A, Trosan P, Skalicka P, Utheim TP, Jirsova K (2019)
Interleukin-13 maintains the stemness of conjunctival epithelial cell cultures prepared from human limbal explants
PLoS One, 14 (2), e0211861
DOI 10.1371/journal.pone.0211861, PubMed 30742646

Tiedemann D, Mouhammad ZA, Utheim TP, Dartt DA, Heegaard S, Petrovski G, Kolko M (2019)
Conjunctival Goblet Cells, the Overlooked Cells in Glaucoma Treatment
J Glaucoma, 28 (4), 325-333
DOI 10.1097/IJG.0000000000001168, PubMed 30585937

Utheim OA, Pasovic L, Raeder S, Eidet JR, Fostad IG, Sehic A, Roald B, de la Paz MF, Lyberg T, Dartt DA, Utheim TP (2019)
Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells
PLoS One, 14 (3), e0212524
DOI 10.1371/journal.pone.0212524, PubMed 30861002

Utjés D, Malmstedt J, Teras J, Drzewiecki K, Gullestad HP, Ingvar C, Eriksson H, Gillgren P (2019)
2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial
Lancet, 394 (10197), 471-477
DOI 10.1016/S0140-6736(19)31132-8, PubMed 31280965

Xiao J, Adil MY, Chen X, Utheim ØA, Ræder S, Tønseth KA, Lagali NS, Dartt DA, Utheim TP (2019)
Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity
Am J Ophthalmol, 209, 160-167
DOI 10.1016/j.ajo.2019.09.005, PubMed 31526799

Xiao J, Adil MY, Olafsson J, Chen X, Utheim ØA, Ræder S, Lagali NS, Dartt DA, Utheim TP (2019)
Diagnostic Test Efficacy of Meibomian Gland Morphology and Function
Sci Rep, 9 (1), 17345
DOI 10.1038/s41598-019-54013-4, PubMed 31758085

Yazdani M, Chen X, Tashbayev B, Utheim ØA, Ræder S, Hua Y, Eidet JR, Stojanovic A, Dartt DA, Utheim TP (2019)
Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
Curr Eye Res, 44 (9), 941-947
DOI 10.1080/02713683.2019.1604972, PubMed 30955380

Yazdani M, Elgstøen KBP, Rootwelt H, Shahdadfar A, Utheim ØA, Utheim TP (2019)
Tear Metabolomics in Dry Eye Disease: A Review
Int J Mol Sci, 20 (15)
DOI 10.3390/ijms20153755, PubMed 31374809

Yazdani M, Shahdadfar A, Jackson CJ, Utheim TP (2019)
Hyaluronan-Based Hydrogel Scaffolds for Limbal Stem Cell Transplantation: A Review
Cells, 8 (3)
DOI 10.3390/cells8030245, PubMed 30875861

Yazdani M, Shahdadfar A, Jackson CJ, Utheim TP (2019)
A Hyaluronan Hydrogel Scaffold for Culture of Human Oral Mucosal Epithelial Cells in Limbal Stem-Cell Therapy
Bioengineering (Basel), 6 (4)
DOI 10.3390/bioengineering6040097, PubMed 31652804

 
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