Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Cardiology B (Div Med)

34 publications found

Agewall S (2020)
Focus on pharma in acute coronary syndrome
Eur Heart J Cardiovasc Pharmacother, 6 (1), 1-2
DOI 10.1093/ehjcvp/pvz074, PubMed 31909430

Atar D, Berge E, Le Heuzey JY, Virdone S, Camm AJ, Steffel J, Gibbs H, Goldhaber SZ, Goto S, Kayani G, Misselwitz F, Stepinska J, Turpie AGG, Bassand JP, Kakkar AK, GARFIELD-AF Investigators (2020)
The association between patterns of atrial fibrillation, anticoagulation, and cardiovascular events
Europace, 22 (2), 195-204
DOI 10.1093/europace/euz292, PubMed 31747004

Bittner VA, Szarek M, Aylward PE, Bhatt DL, Diaz R, Edelberg JM, Fras Z, Goodman SG, Halvorsen S, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Moriarty PM, Moryusef A, Pordy R, Roe MT, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG et al. (2020)
Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome
J Am Coll Cardiol, 75 (2), 133-144
DOI 10.1016/j.jacc.2019.10.057, PubMed 31948641

Bjørkavoll-Bergseth M, Kleiven Ø, Auestad B, Eftestøl T, Oskal K, Nygård M, Skadberg Ø, Aakre KM, Melberg T, Gjesdal K, Ørn S (2020)
Duration of Elevated Heart Rate Is an Important Predictor of Exercise-Induced Troponin Elevation
J Am Heart Assoc, 9 (4), e014408
DOI 10.1161/JAHA.119.014408, PubMed 32065043

Bratseth V, Margeirsdottir HD, Heier M, Solheim S, Arnesen H, Dahl-Jørgensen K, Seljeflot I (2020)
Procoagulant activity in children and adolescents on intensive insulin therapy
Pediatr Diabetes (in press)
DOI 10.1111/pedi.12978, PubMed 31943582

Cadilhac DA, Kim J, Wilsno A, Berge E, Patel A, Ali M, Saver J, Christensen H, Cuche M, Crews S, Wu O, Provoyeur M, McMeekin P, Durand-Zaleski I, Ford GA, Muhlemann N, Bath PM, Abdul-Rahim AH, Sunnerhagen K, Meretoja A, Thijs V, Weimar C, Massaro A, Ranta A, Lees KR et al. (2020)
Improving economic evaluations in stroke: A report from the ESO Health Economics Working Group
Eur. Stroke J., 2396987319897466

Danielsen SO, Moons P, Leegaard M, Solheim S, Tønnessen T, Lie I (2020)
Facilitators of and barriers to reducing thirty-day readmissions and improving patient-reported outcomes after surgical aortic valve replacement: a process evaluation of the AVRre trial
BMC Health Serv Res, 20 (1), 256
DOI 10.1186/s12913-020-05125-5, PubMed 32220252

Drexel H, Rosano GMC, Lewis BS, Huber K, Vonbank A, Dopheide JF, Mader A, Niessner A, Savarese G, Wassmann S, Agewall S (2020)
The age of randomized clinical trials: three important aspects of randomized clinical trials in cardiovascular pharmacotherapy with examples from lipid and diabetes trials
Eur Heart J Cardiovasc Pharmacother, 6 (2), 97-103
DOI 10.1093/ehjcvp/pvz029, PubMed 31298686

Frankenstein L, Seide S, Täger T, Jensen K, Fröhlich H, Clark AL, Seiz M, Katus HA, Nee P, Uhlmann L, Naci H, Atar D (2020)
Relative Efficacy of Spironolactone, Eplerenone, and cAnRenone in patients with Chronic Heart failure (RESEARCH): a systematic review and network meta-analysis of randomized controlled trials
Heart Fail Rev, 25 (2), 161-171
DOI 10.1007/s10741-019-09832-y, PubMed 31364027

Gjesdal K (2020)
Langtids EKG: Riktig bruk er viktig
Tidsskr Nor Laegeforen, 140 (5)
DOI 10.4045/tidsskr.20.0200, PubMed 32238969

Godolphin PJ, Bath PM, Partlett C, Berge E, Brown MM, Eliasziw M, Sandset PM, Serena J, Montgomery AA (2020)
Outcome assessment by central adjudicators in randomised stroke trials: Simulation of differential and non-differential misclassification
Eur. Stroke J., 2396987320910047

Gorenek Chair B, Halvorsen S, Kudaiberdieva G, Bueno H, Van Gelder IC, Lettino M, Marin F, Masip J, Mueller C, Okutucu S, Poess J, Potpara TS, Price S, Lip Co-Chair GY (2020)
Atrial fibrillation in acute heart failure: A position statement from the Acute Cardiovascular Care Association and European Heart Rhythm Association of the European Society of Cardiology
Eur Heart J Acute Cardiovasc Care, 2048872619894255
DOI 10.1177/2048872619894255, PubMed 31976747

Gorog DA, Price S, Sibbing D, Baumbach A, Capodanno D, Gigante B, Halvorsen S, Huber K, Lettino M, Leonardi S, Morais J, Rubboli A, Siller-Matula JM, Storey RF, Vranckx P, Rocca B (2020)
Antithrombotic therapy in patients with acute coronary syndrome complicated by cardiogenic shock or out-of-hospital cardiac arrest: a Joint Position Paper from the European Society of Cardiology (ESC) Working Group on Thrombosis, in association with the Acute Cardiovascular Care Association (ACCA) and European Association of Percutaneous Cardiovascular Interventions (EAPCI)
Eur Heart J Cardiovasc Pharmacother (in press)
DOI 10.1093/ehjcvp/pvaa009, PubMed 32049278

Gustavsen A, Njerve IU, Sitras V, Haugen G, Tollofsrud PA, Akkok CA (2020)
A young woman with a transfusion-related pregnancy complication
Tidsskr. Nor. Laegeforen., 140 (1), 58-61

Gustavsen A, Njerve IU, Sitras V, Haugen G, Tølløfsrud PA, Akkök ÇA (2020)
A young woman with a transfusion-related pregnancy complication
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0117, PubMed 31948214

Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Dunér P, Tønnessen T, Lunde IG, Sjaastad I, Brakebusch C, McCulloch AD, Gomez MF, Carlson CR, Christensen G (2020)
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J Am Heart Assoc, 9 (3), e013518
DOI 10.1161/JAHA.119.013518, PubMed 32000579

Hollan I, Ronda N, Dessein P, Agewall S, Karpouzas G, Tamargo J, Niessner A, Savarese G, Rosano G, Kaski JC, Wassmann S, Meroni PL (2020)
Lipid management in rheumatoid arthritis: a position paper of the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology
Eur Heart J Cardiovasc Pharmacother, 6 (2), 104-114
DOI 10.1093/ehjcvp/pvz033, PubMed 31397840

Jortveit J, Halvorsen S, Langørgen J (2020)
Pharmacy-dispensed drugs for secondary prevention after myocardial infarction
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.19.0416, PubMed 32192264

Jortveit J, Pripp AH, Langørgen J, Halvorsen S (2020)
Incidence, risk factors and outcome of young patients with myocardial infarction
Heart (in press)
DOI 10.1136/heartjnl-2019-316067, PubMed 32111640

Kjeldsen SE, Halvorsen S, Wyller TB, Bath PM, Sandercock P (2020)
Eivind Berge, MD, PhD, 1964-2020: Cardiologist Who Was Fighting Stroke
Stroke, STROKEAHA120029351 (in press)
DOI 10.1161/STROKEAHA.120.029351, PubMed 32200755

Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, Prescott E, Storey RF, Deaton C, Cuisset T, Agewall S, Dickstein K, Edvardsen T, Escaned J, Gersh BJ, Svitil P, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Valgimigli M, Achenbach S, Bax JJ et al. (2020)
2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes
Eur Heart J, 41 (3), 407-477
DOI 10.1093/eurheartj/ehz425, PubMed 31504439

Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138

Langseth MS, Helseth R, Ritschel V, Hansen CH, Andersen GØ, Eritsland J, Halvorsen S, Fagerland MW, Solheim S, Arnesen H, Seljeflot I, Opstad TB (2020)
Double-Stranded DNA and NETs Components in Relation to Clinical Outcome After ST-Elevation Myocardial Infarction
Sci Rep, 10 (1), 5007
DOI 10.1038/s41598-020-61971-7, PubMed 32193509

Mahfoud F, Azizi M, Ewen S, Pathak A, Ukena C, Blankestijn PJ, Böhm M, Burnier M, Chatellier G, Durand Zaleski I, Grassi G, Joner M, Kandzari DE, Kirtane A, Kjeldsen SE, Lobo MD, Lüscher TF, McEvoy JW, Parati G, Rossignol P, Ruilope L, Schlaich MP, Shahzad A, Sharif F, Sharp ASP et al. (2020)
Proceedings from the 3rd European Clinical Consensus Conference for clinical trials in device-based hypertension therapies
Eur Heart J (in press)
DOI 10.1093/eurheartj/ehaa121, PubMed 32211888

Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail (in press)
DOI 10.1002/ehf2.12596, PubMed 31978943

Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
Resuscitation, 149, 170-179
DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258

Opstad TB, Kalstad AA, Holte KB, Berg TJ, Solheim S, Arnesen H, Seljeflot I (2020)
Shorter Leukocyte Telomere Lengths in Healthy Relatives of Patients with Coronary Heart Disease
Rejuvenation Res
DOI 10.1089/rej.2019.2258, PubMed 31805818

Rutherford OW, Jonasson C, Ghanima W, Söderdahl F, Halvorsen S (2020)
Comparison of dabigatran, rivaroxaban, and apixaban for effectiveness and safety in atrial fibrillation: a nationwide cohort study
Eur Heart J Cardiovasc Pharmacother, 6 (2), 75-85
DOI 10.1093/ehjcvp/pvz086, PubMed 31942972

Savarese G, Reiner MF, Uijl A, D'Amario D, Agewall S, Atar D, Baumgartner I, Borghi C, De Carlo M, Drexel H, Kaski JC, Kjeldsen KP, Kucher N, Lund LH, Niessner A, Semb AG, Schmidt TA, Sulzgruber P, Tamargo J, Vitale C, Wassmann S, Aboyans V, Lewis BS (2020)
Antithrombotic therapy and major adverse limb events in patients with chronic lower extremity arterial disease: systematic review and meta-analysis from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy in Collaboration with the European Society of Cardiology Working Group on Aorta and Peripheral Vascular Diseases
Eur Heart J Cardiovasc Pharmacother, 6 (2), 86-93
DOI 10.1093/ehjcvp/pvz036, PubMed 31392312

Steen T (2020)
Pacemakers for young patients – not so fast
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0794, PubMed 31948213

Stepinska J, Lettino M, Ahrens I, Bueno H, Garcia-Castrillo L, Khoury A, Lancellotti P, Mueller C, Muenzel T, Oleksiak A, Petrino R, Guimenez MR, Zahger D, Vrints CJ, Halvorsen S, de Maria E, Lip GY, Rossini R, Claeys M, Huber K (2020)
Diagnosis and risk stratification of chest pain patients in the emergency department: focus on acute coronary syndromes. A position paper of the Acute Cardiovascular Care Association
Eur Heart J Acute Cardiovasc Care, 9 (1), 76-89
DOI 10.1177/2048872619885346, PubMed 31958018

Tancin Lambert A, Kong XY, Ratajczak-Tretel B, Atar D, Russell D, Skjelland M, Bjerkeli V, Skagen K, Coq M, Schordan E, Firat H, Halvorsen B, Aamodt AH (2020)
Biomarkers Associated with Atrial Fibrillation in Patients with Ischemic Stroke: A Pilot Study from the NOR-FIB Study
Cerebrovasc Dis Extra, 10 (1), 11-20 (in press)
DOI 10.1159/000504529, PubMed 32028277

Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353

Aamodt IT, Lycholip E, Celutkiene J, von Lueder T, Atar D, Falk RS, Hellesø R, Jaarsma T, Strömberg A, Lie I (2020)
Self-Care Monitoring of Heart Failure Symptoms and Lung Impedance at Home Following Hospital Discharge: Longitudinal Study
J Med Internet Res, 22 (1), e15445
DOI 10.2196/15445, PubMed 31909717

 
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