Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Cardiology B (Div Med)

46 publications found

Agewall S (2019)
EHJ Cardiovascular Pharmacotherapy has Impact Factor
Eur Heart J, 40 (7), 572
DOI 10.1093/eurheartj/ehy897, PubMed 30768210

Atar D (2019)
Editor's Note
Cardiology, 142 (1), 1
DOI 10.1159/000497089, PubMed 30852568

Atar D, Grundvold I (2019)
On-label reduced doses of non-vitamin K anticoagulants prove safe and efficient; yet how to ensure the correct dose for the right patient?
Eur Heart J, 40 (19), 1501-1503
DOI 10.1093/eurheartj/ehz014, PubMed 30753396

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2019)
Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population
Atherosclerosis, 286, 53-59 (in press)
DOI 10.1016/j.atherosclerosis.2019.05.004, PubMed 31100620

Borer JS, Atar D, Marciniak T, Kim MH, Serebruany V (2019)
Atrial Fibrillation and Stroke in Patients with Hypertrophic Cardiomyopathy: Important New Insights
Thromb Haemost, 119 (3), 355-357
DOI 10.1055/s-0039-1678724, PubMed 30759487

Bratseth V, Chiva-Blanch G, Byrkjeland R, Solheim S, Arnesen H, Seljeflot I (2019)
Elevated levels of circulating microvesicles in coronary artery disease patients with type 2 diabetes and albuminuria: Effects of exercise training
Diab Vasc Dis Res, 1479164119843094 (in press)
DOI 10.1177/1479164119843094, PubMed 31023084

Chin KL, Ofori-Asenso R, Hopper I, von Lueder TG, Reid CM, Zoungas S, Wang BH, Liew D (2019)
Potential mechanisms underlying the cardiovascular benefits of sodium glucose cotransporter 2 inhibitors: a systematic review of data from preclinical studies
Cardiovasc Res, 115 (2), 266-276
DOI 10.1093/cvr/cvy295, PubMed 30475996

Cwikiel J, Seljeflot I, Fagerland MW, Wachtell K, Arnesen H, Berge E, Flaa A (2019)
High-sensitive cardiac Troponin T and exercise stress test for evaluation of angiographically significant coronary disease
Int J Cardiol, 287, 1-6
DOI 10.1016/j.ijcard.2019.04.019, PubMed 31006595

Dahl Aarvik M, Sandven I, Dondo TB, Gale CP, Ruddox V, Munkhaugen J, Atar D, Otterstad JE (2019)
Effect of oral β-blocker treatment on mortality in contemporary post-myocardial infarction patients: a systematic review and meta-analysis
Eur Heart J Cardiovasc Pharmacother, 5 (1), 12-20
DOI 10.1093/ehjcvp/pvy034, PubMed 30192930

Egan BM, Kjeldsen SE, Grassi G, Esler M, Mancia G (2019)
The global burden of hypertension exceeds 1.4 billion people: should a systolic blood pressure target below 130 become the universal standard?
J Hypertens, 37 (6), 1148-1153
DOI 10.1097/HJH.0000000000002021, PubMed 30624370

Fernandes A, McEvoy JW, Halvorsen S (2019)
"Doctor, Should I Keep Taking an Aspirin a Day?"
N Engl J Med, 380 (20), 1967-1970
DOI 10.1056/NEJMclde1903004, PubMed 31091380

Fröhlich H, Rosenfeld N, Täger T, Goode K, Kazmi S, Hole T, Katus HA, Atar D, Cleland JGF, Agewall S, Clark AL, Frankenstein L, Grundtvig M (2019)
Epidemiology and long-term outcome in outpatients with chronic heart failure in Northwestern Europe
Heart (in press)
DOI 10.1136/heartjnl-2018-314256, PubMed 30792238

Hausvater A, Pasupathy S, Tornvall P, Gandhi H, Tavella R, Beltrame J, Agewall S, Ekenbäck C, Brolin EB, Hochman JS, Collste O, Reynolds HR (2019)
ST-segment elevation and cardiac magnetic resonance imaging findings in myocardial infarction with non-obstructive coronary arteries
Int J Cardiol, 287, 128-131
DOI 10.1016/j.ijcard.2019.04.028, PubMed 31003795

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ et al. (2019)
Medical misinformation: vet the message!
Cardiovasc Res (in press)
DOI 10.1093/cvr/cvz007, PubMed 30689762

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ et al. (2019)
Medical Misinformation: Vet the Message!
J Cardiovasc Pharmacol, 73 (2), 61-62
DOI 10.1097/FJC.0000000000000648, PubMed 30730472

Hjort M, Eggers KM, Lindhagen L, Agewall S, Brolin EB, Collste O, Daniel M, Ekenbäck C, Frick M, Henareh L, Hofman-Bang C, Malmqvist K, Spaak J, Sörensson P, Y-Hassan S, Tornvall P, Lindahl B (2019)
Increased Inflammatory Activity in Patients 3 Months after Myocardial Infarction with Nonobstructive Coronary Arteries
Clin Chem (in press)
DOI 10.1373/clinchem.2018.301085, PubMed 31072836

Holte KB, Svanteson M, Hanssen KF, Haig Y, Solheim S, Berg TJ (2019)
Undiagnosed coronary artery disease in long-term type 1 diabetes. The Dialong study
J Diabetes Complications, 33 (5), 383-389
DOI 10.1016/j.jdiacomp.2019.01.006, PubMed 30846232

Jortveit J, Halvorsen S, Kaldal A, Pripp AH, Govatsmark RES, Langørgen J (2019)
Unsatisfactory risk factor control and high rate of new cardiovascular events in patients with myocardial infarction and prior coronary artery disease
BMC Cardiovasc Disord, 19 (1), 71
DOI 10.1186/s12872-019-1062-y, PubMed 30922234

Jortveit J, Pripp AH, Langørgen J, Halvorsen S (2019)
Poor adherence to guideline recommendations among patients with atrial fibrillation and acute myocardial infarction
Eur J Prev Cardiol, 2047487319841940 (in press)
DOI 10.1177/2047487319841940, PubMed 30966816

Kjeldsen SE, Aksnes TA, Mo R, Klemsdal TO (2019)
Impact of the New ACC/AHA and ESC/ESH Hypertension Guidelines for Norway
Eur Heart J, 40 (19), 1485-1487
DOI 10.1093/eurheartj/ehz266, PubMed 31087051

Kjeldsen SE, Mancia G (2019)
Unattended automated office vs. ambulatory blood pressure in people with high cardiovascular risk: implications for understanding the SPRINT results
J Hypertens, 37 (1), 6-8
DOI 10.1097/HJH.0000000000001874, PubMed 30499916

Kjeldsen SE, Narkiewicz K, Burnier M, Oparil S (2019)
Need for multiple risk reduction strategies in clinical trials enrolling high risk patients - FOURIER investigating PCSK-9 inhibitor to lower cholesterol revisited
Blood Press, 28 (3), 144-145
DOI 10.1080/08037051.2019.1614278, PubMed 31076016

Knudsen EC, Seljeflot I, Aksnes TA, Eritsland J, Arnesen H, Andersen GØ (2019)
IgM antibodies against phosphorylcholine measured early after acute ST-elevation myocardial infarction in relation to atherosclerotic disease burden and long-term clinical outcome
PLoS One, 14 (4), e0215640
DOI 10.1371/journal.pone.0215640, PubMed 31002684

Kotecha D, Flather MD, Atar D, Collins P, Pepper J, Jenkins E, Reid CM, Eccleston D, Alternative Risk Markers in Coronary Artery Disease (ARM-CAD) Study (2019)
B-type natriuretic peptide trumps other prognostic markers in patients assessed for coronary disease
BMC Med, 17 (1), 72
DOI 10.1186/s12916-019-1306-9, PubMed 30943979

Lip GYH, Collet JP, Haude M, Byrne R, Chung EH, Fauchier L, Halvorsen S, Lau D, Lopez-Cabanillas N, Lettino M, Marin F, Obel I, Rubboli A, Storey RF, Valgimigli M, Huber K, ESC Scientific Document Group (2019)
2018 Joint European consensus document on the management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous cardiovascular interventions: a joint consensus document of the European Heart Rhythm Association (EHRA), European Society of Cardiology Working Group on Thrombosis, European Association of Percutaneous Cardiovascular Interventions (EAPCI), and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), Latin America Heart Rhythm Society (LAHRS), and Cardiac Arrhythmia Society of Southern Africa (CASSA)
Europace, 21 (2), 192-193
DOI 10.1093/europace/euy174, PubMed 30052888

Mariampillai JE, Prestgaard EE, Kjeldsen SE, Liestøl K, Engeseth K, Erikssen J, Bodegard J, Berge E, Grundvold I, Skretteberg PT (2019)
SBP above 180 mmHg at moderate exercise workload increases coronary heart disease risk in healthy men during 28-year follow-up
J Hypertens, 37 (5), 949-955
DOI 10.1097/HJH.0000000000001959, PubMed 30325341

Mehlum MH, Liestøl K, Wyller TB, Hua TA, Rostrup M, Berge E (2019)
Blood pressure variability in hypertensive patients with atrial fibrillation in the VALUE trial
Blood Press, 28 (2), 77-83
DOI 10.1080/08037051.2018.1524707, PubMed 30614275

Navarese EP, Andreotti F, Raggi P, Kolodziejczak M, Buffon A, Bliden K, Tantry U, Kubica J, Sardella G, Lauten A, Agewall S, Gurbel PA, Brouwer MA (2019)
Baseline low-density lipoprotein cholesterol to predict the extent of cardiovascular benefit from lipid-lowering therapies: a review
Eur Heart J Cardiovasc Pharmacother, 5 (1), 47-54
DOI 10.1093/ehjcvp/pvy038, PubMed 30247574

Opstad TB, Kalstad AA, Pettersen AÅ, Arnesen H, Seljeflot I (2019)
Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease
Exp Gerontol, 119, 53-60
DOI 10.1016/j.exger.2019.01.020, PubMed 30684534

Piira A, Lannem AM, Sørensen M, Glott T, Knutsen R, Jørgensen L, Gjesdal K, Hjeltnes N, Knutsen SF (2019)
Manually assisted body-weight supported locomotor training does not re-establish walking in non-walking subjects with chronic incomplete spinal cord injury: A randomized clinical trial
J Rehabil Med, 51 (2), 113-119
DOI 10.2340/16501977-2508, PubMed 30483724

Piira A, Lannem AM, Sørensen M, Glott T, Knutsen R, Jørgensen L, Gjesdal K, Hjeltnes N, Knutsen SF (2019)
Robot-assisted locomotor training did not improve walking function in patients with chronic incomplete spinal cord injury: A randomized clinical trial
J Rehabil Med, 51 (5), 385-389
DOI 10.2340/16501977-2547, PubMed 30895326

Rosano GMC, Spoletini I, Agewall S (2019)
Pharmacology of new treatments for hyperkalaemia: patiromer and sodium zirconium cyclosilicate
Eur Heart J Suppl, 21 (Suppl A), A28-A33
DOI 10.1093/eurheartj/suy035, PubMed 30837802

Røe ÅT, Ruud M, Espe EK, Manfra O, Longobardi S, Aronsen JM, Nordén ES, Husebye T, Kolstad TRS, Cataliotti A, Christensen G, Sejersted OM, Niederer SA, Andersen GØ, Sjaastad I, Louch WE (2019)
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc Res, 115 (4), 752-764
DOI 10.1093/cvr/cvy257, PubMed 30351410

Salam A, Atkins E, Sundström J, Hirakawa Y, Ettehad D, Emdin C, Neal B, Woodward M, Chalmers J, Berge E, Yusuf S, Rahimi K, Rodgers A, Blood Pressure Lowering Treatment Trialists’ Collaboration (2019)
Effects of blood pressure lowering on cardiovascular events, in the context of regression to the mean: a systematic review of randomized trials
J Hypertens, 37 (1), 16-23
DOI 10.1097/HJH.0000000000001994, PubMed 30499920

Smiseth OA, Kjeldsen SE, Andersen OS, Mistry N, Westheim AS, Skulstad H, Gude E (2019)
Heart Failure with normal ejection fraction
Tidsskr. Nor. Laegeforen., 139 (6), 522-527

Smiseth OA, Kjeldsen SE, Andersen ØS, Mistry N, Westheim AS, Skulstad H, Gude E (2019)
Hjertesvikt med normal ejeksjonsfraksjon
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.18.0523, PubMed 30917641

Solberg OG, Stavem K, Ragnarsson A, Beitnes JO, Skårdal R, Seljeflot I, Ueland T, Aukrust P, Gullestad L, Aaberge L (2019)
Index of microvascular resistance to assess the effect of rosuvastatin on microvascular function in women with chest pain and no obstructive coronary artery disease: A double-blind randomized study
Catheter Cardiovasc Interv (in press)
DOI 10.1002/ccd.28157, PubMed 30790446

Steen T, Sciaraffia E, Normand C, Bogale N, Dickstein K, Linde C, Philbert BT (2019)
Contemporary practice of CRT implantation in scandinavia compared to Europe
Scand Cardiovasc J, 53 (1), 9-13
DOI 10.1080/14017431.2019.1583364, PubMed 30761919

Stokke IM, Li ZB, Cicala S, Okin PM, Kjeldsen SE, Devereux RB, Wachtell K (2019)
Association of left bundle branch block with new onset abnormal wall motion in treated hypertensive patients with left ventricle hypertrophy: the LIFE Echo Sub-study
Blood Press, 28 (2), 84-92
DOI 10.1080/08037051.2019.1569463, PubMed 30698038

Strømnes LA, Ree H, Gjesdal K, Ariansen I (2019)
Sex Differences in Quality of Life in Patients With Atrial Fibrillation: A Systematic Review
J Am Heart Assoc, 8 (8), e010992
DOI 10.1161/JAHA.118.010992, PubMed 30957624

Stubnova V, Os I, Høieggen A, Solbu MD, Grundtvig M, Westheim AS, Atar D, Waldum-Grevbo B (2019)
Gender differences in association between uric acid and all-cause mortality in patients with chronic heart failure
BMC Cardiovasc Disord, 19 (1), 4
DOI 10.1186/s12872-018-0989-8, PubMed 30611196

Tamis-Holland JE, Jneid H, Reynolds HR, Agewall S, Brilakis ES, Brown TM, Lerman A, Cushman M, Kumbhani DJ, Arslanian-Engoren C, Bolger AF, Beltrame JF, American Heart Association Interventional Cardiovascular Care Committee of the Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Epidemiology and Prevention; and Council on Quality of Care and Outcomes Research (2019)
Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association
Circulation, 139 (18), e891-e908
DOI 10.1161/CIR.0000000000000670, PubMed 30913893

Täger T, Fröhlich H, Grundtvig M, Seiz M, Schellberg D, Goode K, Kazmi S, Hole T, Katus HA, Atar D, Cleland JGF, Agewall S, Clark AL, Frankenstein L (2019)
Comparative effectiveness of loop diuretics on mortality in the treatment of patients with chronic heart failure - A multicenter propensity score matched analysis
Int J Cardiol (in press)
DOI 10.1016/j.ijcard.2019.01.109, PubMed 30827731

Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E et al. (2019)
[2018 ESC/ESH Guidelines for the management of arterial hypertension]
Kardiol Pol, 77 (2), 71-159
DOI 10.5603/KP.2019.0018, PubMed 30816983

Zaidi H, Byrkjeland R, Njerve IU, Åkra S, Solheim S, Arnesen H, Seljeflot I, Opstad TB (2019)
Effects of exercise training on inflammasome-related mediators and their associations to glucometabolic variables in patients with combined coronary artery disease and type 2 diabetes mellitus: Sub-study of a randomized control trial
Diab Vasc Dis Res, 1479164119836922 (in press)
DOI 10.1177/1479164119836922, PubMed 30939905

Aamodt IT, Lycholip E, Celutkiene J, Strömberg A, Atar D, Falk RS, von Lueder T, Hellesø R, Jaarsma T, Lie I (2019)
Health Care Professionals' Perceptions of Home Telemonitoring in Heart Failure Care: Cross-Sectional Survey
J Med Internet Res, 21 (2), e10362
DOI 10.2196/10362, PubMed 30724744

 
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