Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2018 from OUS - Department of Cardiology B (Div Med)
70 publications found
Questions and Answers on Diagnosis and Management of Patients with Peripheral Arterial Diseases: A Companion Document of the 2017 ESC Guidelines for the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)
Eur J Vasc Endovasc Surg, 55 (4), 457-464
DOI 10.1016/j.ejvs.2017.08.014, PubMed 29628287
High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure
Int J Cardiol, 277, 166-172
DOI 10.1016/j.ijcard.2018.10.079, PubMed 30416028
Interleukin-18 and the NLR family pyrin domain containing-3 inflammasome in adipose tissue are strongly associated with glucometabolic variables in a cohort of middle-aged men
Diab Vasc Dis Res, 15 (5), 458-464
DOI 10.1177/1479164118785307, PubMed 29972041
Outcomes of apixaban versus warfarin in patients with atrial fibrillation and multi-morbidity: Insights from the ARISTOTLE trial
Am Heart J, 208, 123-131
DOI 10.1016/j.ahj.2018.09.017, PubMed 30579505
Do We Need Potent Intravenous Antiplatelet Inhibition at the Time of Reperfusion During ST-Segment Elevation Myocardial Infarction?
J Cardiovasc Pharmacol Ther, 24 (3), 215-224
DOI 10.1177/1074248418812167, PubMed 30563349
The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging
Ann Noninvasive Electrocardiol, 23 (6), e12580
DOI 10.1111/anec.12580, PubMed 29971868
Correlation of anteroseptal ST elevation with myocardial infarction territories through cardiovascular magnetic resonance imaging
J Electrocardiol, 51 (4), 563-568
DOI 10.1016/j.jelectrocard.2018.03.016, PubMed 29996989
Mechanisms of action and clinical use of specific reversal agents for non-vitamin K antagonist oral anticoagulants
Scand Cardiovasc J, 52 (3), 156-162
DOI 10.1080/14017431.2018.1453613, PubMed 29569500
Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study
Diabetol Metab Syndr, 10, 59
DOI 10.1186/s13098-018-0360-3, PubMed 30038669
Use of ticagrelor alongside fibrinolytic therapy in patients with ST-segment elevation myocardial infarction: Practical perspectives based on data from the TREAT study
Clin Cardiol, 41 (10), 1322-1327
DOI 10.1002/clc.23043, PubMed 30098028
Microvascular perfusion in infarcted and remote myocardium after successful primary PCI: angiographic and CMR findings
Eur Radiol, 29 (2), 941-950
DOI 10.1007/s00330-018-5588-7, PubMed 29980929
MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI
PLoS One, 13 (11), e0206723
DOI 10.1371/journal.pone.0206723, PubMed 30412607
Trifecta has lower gradient and less prosthesis-patient mismatch than Mosaic Ultra in the aortic position: A prospective randomized study
J Thorac Cardiovasc Surg, 158 (4), 1032-1039
DOI 10.1016/j.jtcvs.2018.11.020, PubMed 30635187
Diagnosing heart failure with NT-proBNP point-of-care testing: lower costs and better outcomes. A decision analytic study
BJGP Open, 2 (3), bjgpopen18X101596
DOI 10.3399/bjgpopen18X101596, PubMed 30564729
Effect of apixaban compared with warfarin on coagulation markers in atrial fibrillation
Heart, 105 (3), 235-242
DOI 10.1136/heartjnl-2018-313351, PubMed 30209126
Effect of strenuous exercise on mediators of inflammation in patients with coronary artery disease
Cytokine, 105, 17-22
DOI 10.1016/j.cyto.2018.02.006, PubMed 29433015
Antiarrhythmic drugs-clinical use and clinical decision making: a consensus document from the European Heart Rhythm Association (EHRA) and European Society of Cardiology (ESC) Working Group on Cardiovascular Pharmacology, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and International Society of Cardiovascular Pharmacotherapy (ISCP)
Europace, 20 (5), 731-732an
DOI 10.1093/europace/eux373, PubMed 29438514
Thirty-day readmissions in surgical and transcatheter aortic valve replacement: A systematic review and meta-analysis
Int J Cardiol, 268, 85-91
DOI 10.1016/j.ijcard.2018.05.026, PubMed 29779575
Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
Liver Int, 39 (2), 371-381
DOI 10.1111/liv.13979, PubMed 30269440
sST2 Predicts Outcome in Chronic Heart Failure Beyond NT-proBNP and High-Sensitivity Troponin T
J Am Coll Cardiol, 72 (19), 2309-2320
DOI 10.1016/j.jacc.2018.08.2165, PubMed 30384887
Physical fitness is a modifiable predictor of early cardiovascular death: A 35-year follow-up study of 2014 healthy middle-aged men
Eur J Prev Cardiol, 25 (15), 1655-1663
DOI 10.1177/2047487318793459, PubMed 30103630
Cross-sectional and longitudinal analyses of the association between lung function and exercise capacity in healthy Norwegian men
BMC Pulm Med, 18 (1), 118
DOI 10.1186/s12890-018-0655-z, PubMed 30021542
Cardiovascular risk profile at the age of 40-45 in women with previous hyperemesis gravidarum or hypertensive disorders in pregnancy: A population-based study
Pregnancy Hypertens, 12, 129-135
DOI 10.1016/j.preghy.2018.04.013, PubMed 29858105
Comparative effectiveness of enalapril, lisinopril, and ramipril in the treatment of patients with chronic heart failure: a propensity score-matched cohort study
Eur Heart J Cardiovasc Pharmacother, 4 (2), 82-92
DOI 10.1093/ehjcvp/pvx013, PubMed 28475676
Relationship between left ventricular ejection fraction and mortality after myocardial infarction complicated by heart failure or left ventricular dysfunction
Int J Cardiol, 272, 260-266
DOI 10.1016/j.ijcard.2018.07.137, PubMed 30144995
Markers of Thrombin Generation Are Associated With Long-Term Clinical Outcome in Patients With ST-Segment Elevation Myocardial Infarction
Clin Appl Thromb Hemost, 24 (7), 1088-1094
DOI 10.1177/1076029618764847, PubMed 29695176
Effect of candesartan and metoprolol on myocardial tissue composition during anthracycline treatment: the PRADA trial
Eur Heart J Cardiovasc Imaging, 19 (5), 544-552
DOI 10.1093/ehjci/jex159, PubMed 29106497
Preserved endothelial function in young adults with type 1 diabetes
PLoS One, 13 (10), e0206523
DOI 10.1371/journal.pone.0206523, PubMed 30359432
Increased arterial stiffness in childhood onset diabetes: a cardiovascular magnetic resonance study
Eur Heart J Cardiovasc Imaging, 19 (6), 694-700
DOI 10.1093/ehjci/jex178, PubMed 28950341
Which Target Blood Pressure in Year 2018? Evidence from Recent Clinical Trials
High Blood Press Cardiovasc Prev, 25 (2), 151-158
DOI 10.1007/s40292-018-0258-z, PubMed 29663195
Hypothermia elongates the contraction-relaxation cycle in explanted human failing heart decreasing the time for ventricular filling during diastole
Am J Physiol Heart Circ Physiol, 315 (5), H1137-H1147
DOI 10.1152/ajpheart.00208.2018, PubMed 30004809
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
Sci Rep, 8 (1), 6725
DOI 10.1038/s41598-018-25168-3, PubMed 29712976
Access site complications after transfemoral aortic valve implantation - a comparison of Manta and ProGlide
CVIR Endovasc, 1 (1), 20
DOI 10.1186/s42155-018-0026-0, PubMed 30652151
High-sensitivity troponin I in persistent atrial fibrillation - relation to NT-proBNP and markers of inflammation and haemostasis
Scand J Clin Lab Invest, 78 (5), 386-392
DOI 10.1080/00365513.2018.1481224, PubMed 29933716
2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC)
Eur Heart J, 39 (2), 119-177
DOI 10.1093/eurheartj/ehx393, PubMed 28886621
Correlation of ST changes in leads V4-V6 to area of ischemia by CMR in inferior STEMI
Scand Cardiovasc J, 52 (4), 189-195
DOI 10.1080/14017431.2018.1458145, PubMed 29595340
Cardiac Magnetic Resonance Evaluation of the Extent of Myocardial Injury in Patients with Inferior ST Elevation Myocardial Infarction and Concomitant ST Depression in Leads V1-V3: Analysis from the MITOCARE Study
Cardiology, 140 (3), 178-185
DOI 10.1159/000491745, PubMed 30099440
Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure: A meta-analysis of individual participant data
PLoS Med, 15 (3), e1002538
DOI 10.1371/journal.pmed.1002538, PubMed 29558462
Angiotensin receptor neprilysin inhibition provides superior cardioprotection compared to angiotensin converting enzyme inhibition after experimental myocardial infarction
Int J Cardiol, 258, 192-198
DOI 10.1016/j.ijcard.2018.01.077, PubMed 29544929
Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference
Europace, 20 (3), 395-407
DOI 10.1093/europace/eux318, PubMed 29300976
Markers of neutrophil extracellular traps are associated with adverse clinical outcome in stable coronary artery disease
Eur J Prev Cardiol, 25 (7), 762-769
DOI 10.1177/2047487318760618, PubMed 29473463
Catheter-based left atrial appendage closure
Tidsskr Nor Laegeforen, 138 (7)
DOI 10.4045/tidsskr.17.0601, PubMed 29663763
Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
ESC Heart Fail, 5 (5), 977-984
DOI 10.1002/ehf2.12332, PubMed 30088346
Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks
Eur Heart J, 39 (24), 2243-2251
DOI 10.1093/eurheartj/ehx760, PubMed 29365085
A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
Cardiovasc Res, 114 (12), 1680-1690
DOI 10.1093/cvr/cvy141, PubMed 29878127
Managing patients with prediabetes and type 2 diabetes after coronary events: individual tailoring needed - a cross-sectional study
BMC Cardiovasc Disord, 18 (1), 160
DOI 10.1186/s12872-018-0896-z, PubMed 30075751
BEtablocker Treatment After acute Myocardial Infarction in revascularized patients without reduced left ventricular ejection fraction (BETAMI): Rationale and design of a prospective, randomized, open, blinded end point study
Am Heart J, 208, 37-46
DOI 10.1016/j.ahj.2018.10.005, PubMed 30530121
Personality Traits in Patients with Myocardial Infarction with Nonobstructive Coronary Arteries
Am J Med, 132 (3), 374-381.e1
DOI 10.1016/j.amjmed.2018.11.010, PubMed 30503881
Non-insulin antidiabetic pharmacotherapy in patients with established cardiovascular disease: a position paper of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy
Eur Heart J, 39 (24), 2274-2281
DOI 10.1093/eurheartj/ehx625, PubMed 29126266
The heart failure burden of type 2 diabetes mellitus-a review of pathophysiology and interventions
Heart Fail Rev, 23 (3), 303-323
DOI 10.1007/s10741-018-9685-0, PubMed 29516230
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279
Longitudinal left ventricular function is globally depressed within a week of STEMI
Clin Physiol Funct Imaging, 38 (6), 1029-1037
DOI 10.1111/cpf.12521, PubMed 29701310
Dyslipidemia and Risk of Cardiovascular Events in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Therapy: Insights From the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) Trial
J Am Heart Assoc, 7 (3)
DOI 10.1161/JAHA.117.007444, PubMed 29419390
Change in Cardiorespiratory Fitness and Risk of Stroke and Death
Stroke, 50 (1), 155-161
DOI 10.1161/STROKEAHA.118.021798, PubMed 30580727
Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis
Eur Heart J, 39 (19), 1672-1686f
DOI 10.1093/eurheartj/ehy066, PubMed 29509886
Expert consensus document on the management of hyperkalaemia in patients with cardiovascular disease treated with renin angiotensin aldosterone system inhibitors: coordinated by the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology
Eur Heart J Cardiovasc Pharmacother, 4 (3), 180-188
DOI 10.1093/ehjcvp/pvy015, PubMed 29726985
In Current Clinical Practice, after Percutaneous Coronary Intervention for Acute Myocardial Infarction, Are β-Blockers Prescribed for Heart Failure or as Secondary Prevention? A Pilot Study
Cardiology, 140 (3), 152-154
DOI 10.1159/000490656, PubMed 30089282
New score for assessing bleeding risk in patients with atrial fibrillation treated with NOACs
Open Heart, 5 (2), e000931
DOI 10.1136/openhrt-2018-000931, PubMed 30613418
Incidence rate of sudden death in epilepsy: A systematic review and meta-analysis
Epilepsy Behav, 86, 193-199
DOI 10.1016/j.yebeh.2018.06.037, PubMed 30017838
Obesity paradox on outcome in atrial fibrillation maintained even considering the prognostic influence of biomarkers: insights from the ARISTOTLE trial
Open Heart, 5 (2), e000908
DOI 10.1136/openhrt-2018-000908, PubMed 30487982
Rivaroxaban plasma levels in acute ischemic stroke and intracerebral hemorrhage
Ann Neurol, 83 (3), 451-459
DOI 10.1002/ana.25165, PubMed 29394504
Association of IL-8 With Infarct Size and Clinical Outcomes in Patients With STEMI
J Am Coll Cardiol, 72 (2), 187-198
DOI 10.1016/j.jacc.2018.04.053, PubMed 29976293
Exercise capacity in COPD patients with exercise-induced pulmonary hypertension
Int J Chron Obstruct Pulmon Dis, 13, 3599-3610
DOI 10.2147/COPD.S161175, PubMed 30464443
Comparison of three haemodynamic monitoring methods in comatose post cardiac arrest patients
Scand Cardiovasc J, 52 (3), 141-148
DOI 10.1080/14017431.2018.1450992, PubMed 29544369
Non-invasive hemodynamic monitoring as a guide to drug treatment of uncontrolled hypertensive patients: effects on home blood pressure in the BEAUTY study
Blood Press, 27 (6), 368-375
DOI 10.1080/08037051.2018.1505425, PubMed 30129785
Characteristics of patients with atrial fibrillation prescribed antiplatelet monotherapy compared with those on anticoagulants: insights from the GARFIELD-AF registry
Eur Heart J, 39 (6), 464-473
DOI 10.1093/eurheartj/ehx730, PubMed 29281086
Reasons for disparity in statin adherence rates between clinical trials and real-world observations: a review
Eur Heart J Cardiovasc Pharmacother, 4 (4), 230-236
DOI 10.1093/ehjcvp/pvy028, PubMed 30099530
2018 Practice Guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension
Blood Press, 27 (6), 314-340
DOI 10.1080/08037051.2018.1527177, PubMed 30380928