Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Dept. of Gastroenterology (Div Medicine)

35 publications found

Al-Toma A, Volta U, Auricchio R, Castillejo G, Sanders DS, Cellier C, Mulder CJ, Lundin KEA (2019)
European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders
United European Gastroenterol J, 7 (5), 583-613
DOI 10.1177/2050640619844125, PubMed 31210940

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019)
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737

Bekkelund M, Sangnes DA, Gunnar Hatlebakk J, Aabakken L (2019)
Pathophysiology of idiopathic gastroparesis and implications for therapy
Scand J Gastroenterol, 54 (1), 8-17
DOI 10.1080/00365521.2018.1558280, PubMed 30638082

Berge ST, Safi N, Medhus AW, Ånonsen K, Sundhagen JO, Hisdal J, Kazmi SSH (2019)
Gastroscopy assisted laser Doppler flowmetry and visible light spectroscopy in patients with chronic mesenteric ischemia
Scand J Clin Lab Invest, 79 (7), 541-549
DOI 10.1080/00365513.2019.1672084, PubMed 31560225

Bjørkhaug ST, Neupane SP, Bramness JG, Aanes H, Skar V, Medhus AW, Valeur J (2019)
Plasma cytokine levels in patients with chronic alcohol overconsumption: relations to gut microbiota markers and clinical correlates
Alcohol (in press)
DOI 10.1016/j.alcohol.2019.10.002, PubMed 31610228

Bjørkhaug ST, Aanes H, Neupane SP, Bramness JG, Malvik S, Henriksen C, Skar V, Medhus AW, Valeur J (2019)
Characterization of gut microbiota composition and functions in patients with chronic alcohol overconsumption
Gut Microbes, 10 (6), 663-675
DOI 10.1080/19490976.2019.1580097, PubMed 30894059

Buer LCT, Moum BA, Cvancarova M, Warren DJ, Bolstad N, Medhus AW, Høivik ML (2019)
Real world data on effectiveness, safety and therapeutic drug monitoring of vedolizumab in patients with inflammatory bowel disease. A single center cohort
Scand J Gastroenterol, 54 (1), 41-48
DOI 10.1080/00365521.2018.1548646, PubMed 30650312

Christophersen A, Lund EG, Snir O, Solà E, Kanduri C, Dahal-Koirala S, Zühlke S, Molberg Ø, Utz PJ, Rohani-Pichavant M, Simard JF, Dekker CL, Lundin KEA, Sollid LM, Davis MM (2019)
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136

Dahal-Koirala S, Neumann RS, Jahnsen J, Lundin KEA, Sollid LM (2019)
On the immune response to barley in celiac disease: Biased and public T-cell receptor usage to a barley unique and immunodominant gluten epitope
Eur J Immunol
DOI 10.1002/eji.201948253, PubMed 31628754

Dale HF, Jensen C, Hausken T, Valeur J, Hoff DAL, Lied GA (2019)
Effects of a Cod Protein Hydrolysate Supplement on Symptoms, Gut Integrity Markers and Fecal Fermentation in Patients with Irritable Bowel Syndrome
Nutrients, 11 (7)
DOI 10.3390/nu11071635, PubMed 31319590

Detlie TE, Lindstrøm JC, Jahnsen ME, Finnes E, Zoller H, Moum B, Jahnsen J (2019)
Incidence of hypophosphatemia in patients with inflammatory bowel disease treated with ferric carboxymaltose or iron isomaltoside
Aliment Pharmacol Ther, 50 (4), 397-406
DOI 10.1111/apt.15386, PubMed 31264261

Evensen H, Kristensen V, Larssen L, Sandstad O, Hauge T, Medhus AW (2019)
Outcome of peroral endoscopic myotomy (POEM) in treatment-naive patients. A systematic review
Scand J Gastroenterol, 54 (1), 1-7
DOI 10.1080/00365521.2018.1549271, PubMed 30650313

Fadnes LT, Aas CF, Vold JH, Ohldieck C, Leiva RA, Chalabianloo F, Skurtveit S, Lygren OJ, Dalgård O, Vickerman P, Midgard H, Løberg EM, Johansson KA, INTRO-HCV Study Group (2019)
Integrated treatment of hepatitis C virus infection among people who inject drugs: study protocol for a randomised controlled trial (INTRO-HCV)
BMC Infect Dis, 19 (1), 943
DOI 10.1186/s12879-019-4598-7, PubMed 31703669

Fazio N, Martini JF, Croitoru AE, Schenker M, Li S, Rosbrook B, Fernandez K, Tomasek J, Thiis-Evensen E, Kulke M, Raymond E (2019)
Pharmacogenomic analyses of sunitinib in patients with pancreatic neuroendocrine tumors
Future Oncol, 15 (17), 1997-2007
DOI 10.2217/fon-2018-0934, PubMed 31084373

Gidoni M, Snir O, Peres A, Polak P, Lindeman I, Mikocziova I, Sarna VK, Lundin KEA, Clouser C, Vigneault F, Collins AM, Sollid LM, Yaari G (2019)
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628
DOI 10.1038/s41467-019-08489-3, PubMed 30733445

Goll GL, Jørgensen KK, Sexton J, Olsen IC, Bolstad N, Haavardsholm EA, Lundin KEA, Tveit KS, Lorentzen M, Berset IP, Fevang BTS, Kalstad S, Ryggen K, Warren DJ, Klaasen RA, Asak Ø, Baigh S, Blomgren IM, Brenna Ø, Bruun TJ, Dvergsnes K, Frigstad SO, Hansen IM, Hatten ISH, Huppertz-Hauss G et al. (2019)
Long-term efficacy and safety of biosimilar infliximab (CT-P13) after switching from originator infliximab: open-label extension of the NOR-SWITCH trial
J Intern Med, 285 (6), 653-669
DOI 10.1111/joim.12880, PubMed 30762274

Grimstad T, Kvivik I, Kvaløy JT, Aabakken L, Omdal R (2019)
Heat-shock protein 90<b>α</b> in plasma reflects severity of fatigue in patients with Crohn's disease
Innate Immun, UNSP 1753425919879988
DOI 10.1177/1753425919879988, PubMed 31601148

Hajarizadeh B, Cunningham EB, Valerio H, Martinello M, Law M, Janjua N, Midgard H, Dalgard O, Dillon J, Hickman M, Bruneau J, Dore GJ, Grebely J (2019)
Hepatitis C reinfection after successful antiviral treatment among people who inject drugs: A meta-analysis
J Hepatol (in press)
DOI 10.1016/j.jhep.2019.11.012, PubMed 31785345

Haraldsson E, Kylänpää L, Grönroos J, Saarela A, Toth E, Qvigstad G, Hult M, Lindström O, Laine S, Karjula H, Hauge T, Sadik R, Arnelo U (2019)
Macroscopic appearance of the major duodenal papilla influences bile duct cannulation: a prospective multicenter study by the Scandinavian Association for Digestive Endoscopy Study Group for ERCP
Gastrointest Endosc, 90 (6), 957-963
DOI 10.1016/j.gie.2019.07.014, PubMed 31326385

Hauge T, Kleven OC, Johnson E, Hofstad B, Johannessen HO (2019)
Outcome after iatrogenic esophageal perforation
Scand J Gastroenterol, 54 (2), 140-144
DOI 10.1080/00365521.2019.1575464, PubMed 30857441

Hære P, Høie O, Lundin KEA, Haugeberg G (2019)
No major reduction in bone mineral density after long-term treatment of patients with Celiac Disease
Eur J Intern Med, 68, 23-29
DOI 10.1016/j.ejim.2019.07.024, PubMed 31401019

Iversen R, Roy B, Stamnaes J, Høydahl LS, Hnida K, Neumann RS, Korponay-Szabó IR, Lundin KEA, Sollid LM (2019)
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344

Kahrs CR, Chuda K, Tapia G, Stene LC, Mårild K, Rasmussen T, Rønningen KS, Lundin KEA, Kramna L, Cinek O, Størdal K (2019)
Enterovirus as trigger of coeliac disease: nested case-control study within prospective birth cohort
BMJ, 364, l231
DOI 10.1136/bmj.l231, PubMed 30760441

Kristensen VA, Valeur J, Brackmann S, Jahnsen J, Brunborg C, Tveito K (2019)
Attention deficit and hyperactivity disorder symptoms respond to gluten-free diet in patients with coeliac disease
Scand J Gastroenterol, 54 (5), 571-576
DOI 10.1080/00365521.2019.1608467, PubMed 31050907

Lindfors K, Ciacci C, Kurppa K, Lundin KEA, Makharia GK, Mearin ML, Murray JA, Verdu EF, Kaukinen K (2019)
Coeliac disease
Nat Rev Dis Primers, 5 (1), 3
DOI 10.1038/s41572-018-0054-z, PubMed 30631077

Olbjørn C, Cvancarova Småstuen M, Thiis-Evensen E, Nakstad B, Vatn MH, Jahnsen J, Ricanek P, Vatn S, Moen AEF, Tannæs TM, Lindstrøm JC, Söderholm JD, Halfvarson J, Gomollón F, Casén C, Karlsson MK, Kalla R, Adams AT, Satsangi J, Perminow G (2019)
Fecal microbiota profiles in treatment-naïve pediatric inflammatory bowel disease - associations with disease phenotype, treatment, and outcome
Clin Exp Gastroenterol, 12, 37-49
DOI 10.2147/CEG.S186235, PubMed 30774408

Olesen SS, Lisitskaya MV, Drewes AM, Novovic S, Nøjgaard C, Kalaitzakis E, Jensen NM, Engjom T, Erchinger F, Waage A, Hauge T, Haas SL, Vujasinovic M, Lindkvist B, Zviniene K, Pukitis A, Ozola-Zālīte I, Okhlobystin A, Parhiala M, Laukkarinen J, Frøkjær JB, Scandinavian Baltic Pancreatic Club (2019)
Pancreatic calcifications associate with diverse aetiological risk factors in patients with chronic pancreatitis: A multicentre study of 1500 cases
Pancreatology, 19 (7), 922-928
DOI 10.1016/j.pan.2019.08.009, PubMed 31462382

Olesen SS, Nøjgaard C, Poulsen JL, Haas SL, Vujasinovic M, Löhr M, Lindkvist B, Bexander L, Gulbinas A, Kalaitzakis E, Ebrahim M, Erchinger F, Engjom T, Roug S, Novovic S, Hauge T, Waage A, Laukkarinen J, Parhiala M, Pukitis A, Ozola-Zālīte I, Drewes AM, Scandinavian Baltic Pancreatic Club (2019)
Chronic Pancreatitis Is Characterized by Distinct Complication Clusters That Associate With Etiological Risk Factors
Am J Gastroenterol, 114 (4), 656-664
DOI 10.14309/ajg.0000000000000147, PubMed 30741740

Safreed-Harmon K, Blach S, Aleman S, Bollerup S, Cooke G, Dalgard O, Dillon JF, Dore GJ, Duberg AS, Grebely J, Boe Kielland K, Midgard H, Porter K, Razavi H, Tyndall M, Weis N, Lazarus JV (2019)
The Consensus Hepatitis C Cascade of Care: Standardized Reporting to Monitor Progress Toward Elimination
Clin Infect Dis, 69 (12), 2218-2227
DOI 10.1093/cid/ciz714, PubMed 31352481

Skodje GI, Minelle IH, Rolfsen KL, Iacovou M, Lundin KEA, Veierød MB, Henriksen C (2019)
Dietary and symptom assessment in adults with self-reported non-coeliac gluten sensitivity
Clin Nutr ESPEN, 31, 88-94
DOI 10.1016/j.clnesp.2019.02.012, PubMed 31060839

Torres J, Ellul P, Langhorst J, Mikocka-Walus A, Barreiro-de Acosta M, Basnayake C, Ding NJS, Gilardi D, Katsanos K, Moser G, Opheim R, Palmela C, Pellino G, Van der Marel S, Vavricka SR (2019)
European Crohn's and Colitis Organisation Topical Review on Complementary Medicine and Psychotherapy in Inflammatory Bowel Disease
J Crohns Colitis, 13 (6), 673-685e
DOI 10.1093/ecco-jcc/jjz051, PubMed 30820529

Tye-Din JA, Skodje GI, Sarna VK, Dzuris JL, Russell AK, Goel G, Wang SY, Goldstein KE, Williams LJ, Sollid LM, Lundin KEA, Anderson RP (2019)
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
United European Gastroenterol. J., UNSP 2050640619874173

Vyakaranam AR, Crona J, Norlén O, Granberg D, Garske-Román U, Sandström M, Fröss-Baron K, Thiis-Evensen E, Hellman P, Sundin A (2019)
Favorable Outcome in Patients with Pheochromocytoma and Paraganglioma Treated with 177Lu-DOTATATE
Cancers (Basel), 11 (7)
DOI 10.3390/cancers11070909, PubMed 31261748

Zuhlke S, Risnes LF, Dahal-Koirala S, Christophersen A, Sollid LM, Lundin KEA (2019)
CD38 expression on gluten-specific T cells is a robust marker of gluten re-exposure in coeliac disease
United European Gastroenterol. J., UNSP 2050640619874183

Ånonsen K, Sahakyan MA, Kleive D, Waage A, Verbeke C, Hauge T, Buanes T, Edwin B, Labori KJ (2019)
Trends in management and outcome of cystic pancreatic lesions - analysis of 322 cases undergoing surgical resection
Scand J Gastroenterol, 54 (8), 1051-1057
DOI 10.1080/00365521.2019.1642379, PubMed 31322457

 
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