Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2017 from OUS - Dept. of Gastroenterology (Div Medicine)

30 publications found

Aghdassi AA, Schneider A, Kahl M, Schütte K, Kuliaviene I, Salacone P, Lutz J, Tukiainen E, Simon P, Schauer B, Uomo G, Hauge T, Ceyhan GO (2017)
Analysis of lifestyle factors in patients with concomitant chronic pancreatitis and liver cirrhosis
Pancreatology, 17 (5), 698-705
DOI 10.1016/j.pan.2017.07.194, PubMed 28784575

Bjørkhaug ST, Skar V, Medhus AW, Tollisen A, Bramness JG, Valeur J (2017)
Chronic alcohol overconsumption may alter gut microbial metabolism: a retrospective study of 719 13C-D-xylose breath test results
Microb Ecol Health Dis, 28 (1), 1301725
DOI 10.1080/16512235.2017.1301725, PubMed 28572752

Bjøro B, Dalgard O, Midgard H, Verbaan H, Småstuen MC, Rustøen T (2017)
Increased hope following successful treatment for hepatitis C infection
J Adv Nurs, 74 (3), 724-733
DOI 10.1111/jan.13487, PubMed 29082540

Buer L, Høivik ML, Medhus AW, Moum B (2017)
Does the Introduction of Biosimilars Change Our Understanding about Treatment Modalities for Inflammatory Bowel Disease?
Dig Dis, 35 (1-2), 74-82
DOI 10.1159/000449087, PubMed 28147370

Buer LC, Moum BA, Cvancarova M, Warren DJ, Medhus AW, Høivik ML (2017)
Switching from Remicade® to Remsima® is well Tolerated and Feasible: A Prospective, Open-label Study
J Crohns Colitis, 11 (3), 297-304
DOI 10.1093/ecco-jcc/jjw166, PubMed 27660339

Bujko A, Atlasy N, Landsverk OJB, Richter L, Yaqub S, Horneland R, Øyen O, Aandahl EM, Aabakken L, Stunnenberg HG, Bækkevold ES, Jahnsen FL (2017)
Transcriptional and functional profiling defines human small intestinal macrophage subsets
J Exp Med, 215 (2), 441-458
DOI 10.1084/jem.20170057, PubMed 29273642

Burisch J, Vegh Z, Katsanos KH, Christodoulou DK, Lazar D, Goldis A, O'Morain C, Fernandez A, Pereira S, Myers S, Sebastian S, Pedersen N, Olse J, Rubek Nielsen K, Schwartz D, Odes S, Almer S, Halfvarson J, Turk N, Cukovic-Cavka S, Nikulina I, Belousova E, Duricova D, Bortlik M, Shonová O et al. (2017)
Occurrence of Anaemia in the First Year of Inflammatory Bowel Disease in a European Population-based Inception Cohort-An ECCO-EpiCom Study
J Crohns Colitis, 11 (10), 1213-1222
DOI 10.1093/ecco-jcc/jjx077, PubMed 28575481

Chellappa S, Hugenschmidt H, Hagness M, Subramani S, Melum E, Line PD, Labori KJ, Wiedswang G, Taskén K, Aandahl EM (2017)
CD8+ T Cells That Coexpress RORγt and T-bet Are Functionally Impaired and Expand in Patients with Distal Bile Duct Cancer
J Immunol, 198 (4), 1729-1739
DOI 10.4049/jimmunol.1600061, PubMed 28053236

Chung BK, Karlsen TH (2017)
Genetic Discoveries Highlight Environmental Factors as Key Drivers of Liver Disease
Dig Dis, 35 (4), 323-333
DOI 10.1159/000456583, PubMed 28468012

de Muinck EJ, Lundin KEA, Trosvik P (2017)
Linking Spatial Structure and Community-Level Biotic Interactions through Cooccurrence and Time Series Modeling of the Human Intestinal Microbiota
mSystems, 2 (5)
DOI 10.1128/mSystems.00086-17, PubMed 28904999

Grebely J, Dalgard O, Cunningham EB, Hajarizadeh B, Foster GR, Bruggmann P, Conway B, Backmund M, Robaeys G, Swan T, Amin J, Marks PS, Quiene S, Applegate TL, Weltman M, Shaw D, Dunlop A, Hellard M, Bruneau J, Midgard H, Bourgeois S, Staehelin C, Dore GJ, ACTIVATE Study Group (2017)
Efficacy of response-guided directly observed pegylated interferon and self-administered ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: The ACTIVATE study
Int J Drug Policy, 47, 177-186
DOI 10.1016/j.drugpo.2017.05.020, PubMed 28624134

Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ (2017)
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
JCI Insight, 2 (17), e95193
DOI 10.1172/jci.insight.95193, PubMed 28878121

Hellum M, Franco-Lie I, Øvstebø R, Hauge T, Henriksson CE (2017)
The effect of corn trypsin inhibitor, anti-tissue factor pathway inhibitor antibodies and phospholipids on microvesicle-associated thrombin generation in patients with pancreatic cancer and healthy controls
PLoS One, 12 (9), e0184579
DOI 10.1371/journal.pone.0184579, PubMed 28910348

Hovde Ø, Høivik ML, Henriksen M, Solberg IC, Småstuen MC, Moum BA (2017)
Malignancies in Patients with Inflammatory Bowel Disease: Results from 20 Years of Follow-up in the IBSEN Study
J Crohns Colitis, 11 (5), 571-577
DOI 10.1093/ecco-jcc/jjw193, PubMed 28453756

Iversen R, Snir O, Stensland M, Kroll JE, Steinsbø Ø, Korponay-Szabó IR, Lundin KEA, de Souza GA, Sollid LM (2017)
Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Cell Rep, 20 (10), 2357-2367
DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470

Jahnsen FL, Bækkevold ES, Hov JR, Landsverk OJ (2017)
Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
Trends Immunol, 39 (3), 196-208
DOI 10.1016/j.it.2017.10.006, PubMed 29162322

Jørgensen KK, Olsen IC, Goll GL, Lorentzen M, Bolstad N, Haavardsholm EA, Lundin KEA, Mørk C, Jahnsen J, Kvien TK, NOR-SWITCH study group (2017)
Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial
Lancet, 389 (10086), 2304-2316
DOI 10.1016/S0140-6736(17)30068-5, PubMed 28502609

Kahrs CR, Magnus MC, Stigum H, Lundin KEA, Størdal K (2017)
Early growth in children with coeliac disease: a cohort study
Arch Dis Child, 102 (11), 1037-1043
DOI 10.1136/archdischild-2016-312304, PubMed 28611068

Kristensen V, Røseth A, Ahmad T, Skar V, Moum B (2017)
Fecal Calprotectin: A Reliable Predictor of Mucosal Healing after Treatment for Active Ulcerative Colitis
Gastroenterol Res Pract, 2017, 2098293
DOI 10.1155/2017/2098293, PubMed 29225617

Lerdal A, Opheim R, Gay CL, Moum B, Fagermoen MS, Kottorp A (2017)
Psychometric limitations of the 13-item Sense of Coherence Scale assessed by Rasch analysis
BMC Psychol, 5 (1), 18
DOI 10.1186/s40359-017-0187-y, PubMed 28595651

Midgard H, Hajarizadeh B, Cunningham EB, Conway B, Backmund M, Bruggmann P, Bruneau J, Bourgeois S, Dunlop A, Foster GR, Hellard M, Robaeys G, Thurnheer MC, Weltman M, Amin J, Marks PS, Quiene S, Dore GJ, Dalgard O, Grebely J, ACTIVATE Study Group (2017)
Changes in risk behaviours during and following treatment for hepatitis C virus infection among people who inject drugs: The ACTIVATE study
Int J Drug Policy, 47, 230-238
DOI 10.1016/j.drugpo.2017.05.040, PubMed 28633998

Roy B, Neumann RS, Snir O, Iversen R, Sandve GK, Lundin KEA, Sollid LM (2017)
High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease
J Immunol, 199 (2), 782-791
DOI 10.4049/jimmunol.1700169, PubMed 28600290

Sarna VK, Lundin KEA, Mørkrid L, Qiao SW, Sollid LM, Christophersen A (2017)
HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
Gastroenterology, 154 (4), 886-896.e6
DOI 10.1053/j.gastro.2017.11.006, PubMed 29146521

Sarna VK, Skodje GI, Reims HM, Risnes LF, Dahal-Koirala S, Sollid LM, Lundin KEA (2017)
HLA-DQ:gluten tetramer test in blood gives better detection of coeliac patients than biopsy after 14-day gluten challenge
Gut, 67 (9), 1606-1613
DOI 10.1136/gutjnl-2017-314461, PubMed 28779027

Schrumpf E, Jiang X, Zeissig S, Pollheimer MJ, Anmarkrud JA, Tan C, Exley MA, Karlsen TH, Blumberg RS, Melum E (2017)
The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation
Physiol Rep, 5 (4)
DOI 10.14814/phy2.13117, PubMed 28219981

Server A, Bargalló N, Fløisand Y, Sponheim J, Graus F, Hald JK (2017)
Imaging spectrum of central nervous system complications of hematopoietic stem cell and solid organ transplantation
Neuroradiology, 59 (2), 105-126
DOI 10.1007/s00234-017-1804-4, PubMed 28255902

Skodje GI, Sarna VK, Minelle IH, Rolfsen KL, Muir JG, Gibson PR, Veierød MB, Henriksen C, Lundin KEA (2017)
Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-Reported Non-Celiac Gluten Sensitivity
Gastroenterology, 154 (3), 529-539.e2
DOI 10.1053/j.gastro.2017.10.040, PubMed 29102613

Snir O, Chen X, Gidoni M, du Pré MF, Zhao Y, Steinsbø Ø, Lundin KE, Yaari G, Sollid LM (2017)
Stereotyped antibody responses target posttranslationally modified gluten in celiac disease
JCI Insight, 2 (17), e93961
DOI 10.1172/jci.insight.93961, PubMed 28878138

Tronstad RR, Kummen M, Holm K, von Volkmann HL, Anmarkrud JA, Høivik ML, Moum B, Gilja OH, Hausken T, Baines J, Karlsen TH, Fiskerstrand T, Hov JR (2017)
Guanylate Cyclase C Activation Shapes the Intestinal Microbiota in Patients with Familial Diarrhea and Increased Susceptibility for Crohn's Disease
Inflamm Bowel Dis, 23 (10), 1752-1761
DOI 10.1097/MIB.0000000000001264, PubMed 28902124

Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472

 
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