Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2015 from OUS - Dept. of Gastroenterology (Div Medicine)

36 publications found

Andresen K, Boberg KM, Vedeld HM, Honne H, Jebsen P, Hektoen M, Wadsworth CA, Clausen OP, Lundin KE, Paulsen V, Foss A, Mathisen Ø, Aabakken L, Schrumpf E, Lothe RA, Lind GE (2015)
Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
Hepatology, 61 (5), 1651-9
DOI 10.1002/hep.27707, PubMed 25644509

Anonsen KV, Buanes T, Rosok BI, Hauge T, Edwin B (2015)
Outcome of Laparoscopic Surgery in Patients with Cystic Lesions in the Distal Pancreas
J. Pancreas, 16 (3), 266-270

Casén C, Vebø HC, Sekelja M, Hegge FT, Karlsson MK, Ciemniejewska E, Dzankovic S, Frøyland C, Nestestog R, Engstrand L, Munkholm P, Nielsen OH, Rogler G, Simrén M, Öhman L, Vatn MH, Rudi K (2015)
Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD
Aliment Pharmacol Ther, 42 (1), 71-83
DOI 10.1111/apt.13236, PubMed 25973666

Di Niro R, Snir O, Kaukinen K, Yaari G, Lundin KE, Gupta NT, Kleinstein SH, Cols M, Cerutti A, Mäki M, Shlomchik MJ, Sollid LM (2015)
Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease
Mucosal Immunol, 9 (1), 254-64
DOI 10.1038/mi.2015.57, PubMed 26153762

Folseraas T, Boberg KM (2015)
Cancer Risk and Surveillance in Primary Sclerosing Cholangitis
Clin Liver Dis, 20 (1), 79-98
DOI 10.1016/j.cld.2015.08.014, PubMed 26593292

Fyhn TJ, Knatten CK, Edwin B, Schistad O, Aabakken L, Kjosbakken H, Pripp AH, Emblem R, Bjørnland K (2015)
Randomized Controlled Trial of Laparoscopic and Open Nissen Fundoplication in Children
Ann Surg, 261 (6), 1061-7
DOI 10.1097/SLA.0000000000001045, PubMed 26291953

Hassan C, Repici A, Sharma P, Correale L, Zullo A, Bretthauer M, Senore C, Spada C, Bellisario C, Bhandari P, Rex DK (2015)
Efficacy and safety of endoscopic resection of large colorectal polyps: a systematic review and meta-analysis
Gut, 65 (5), 806-20
DOI 10.1136/gutjnl-2014-308481, PubMed 25681402

Hauge T, Hauge PW, Warloe T, Drolsum A, Johansen C, Viktil E, Aabakken L, Buanes T, Konopski Z (2015)
Randomised controlled trial of temoporfin photodynamic therapy plus chemotherapy in nonresectable biliary carcinoma--PCS Nordic study
Photodiagnosis Photodyn Ther, 13, 330-333
DOI 10.1016/j.pdpdt.2015.09.004, PubMed 26415549

Hov JR, Zhong H, Qin B, Anmarkrud JA, Holm K, Franke A, Lie BA, Karlsen TH (2015)
The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study
PLoS One, 10 (7), e0133804
DOI 10.1371/journal.pone.0133804, PubMed 26207384

Huppertz-Hauss G, Høivik ML, Langholz E, Odes S, Småstuen M, Stockbrugger R, Hoff G, Moum B, Bernklev T (2015)
Health-related quality of life in inflammatory bowel disease in a European-wide population-based cohort 10 years after diagnosis
Inflamm Bowel Dis, 21 (2), 337-44
DOI 10.1097/MIB.0000000000000272, PubMed 25569735

Jelsness-Jørgensen LP, Bernklev T, Hovde Ø, Prytz Berset I, Huppertz-Hauss G, Moum B, Lie Høivik M (2015)
Patients' perceptions of quality of care and follow-up in inflammatory bowel disease
Scand J Gastroenterol, 51 (4), 434-41
DOI 10.3109/00365521.2015.1102319, PubMed 26635189

Kaminski MF, Anderson J, Valori R, Kraszewska E, Rupinski M, Pachlewski J, Wronska E, Bretthauer M, Thomas-Gibson S, Kuipers EJ, Regula J (2015)
Leadership training to improve adenoma detection rate in screening colonoscopy: a randomised trial
Gut, 65 (4), 616-24
DOI 10.1136/gutjnl-2014-307503, PubMed 25670810

Karlsen TH, Chung BK (2015)
Genetic Risk and the Development of Autoimmune Liver Disease
Dig Dis, 33 Suppl 2, 13-24
DOI 10.1159/000440706, PubMed 26641277

Karlsen TH, Lammert F, Thompson RJ (2015)
Genetics of liver disease: From pathophysiology to clinical practice
J Hepatol, 62 (1 Suppl), S6-S14
DOI 10.1016/j.jhep.2015.02.025, PubMed 25920091

Knatten CK, Kvello M, Fyhn TJ, Edwin B, Schistad O, Aabakken L, Pripp AH, Kjosbakken H, Emblem R, Bjørnland K (2015)
Nissen fundoplication in children with and without neurological impairment: A prospective cohort study
J Pediatr Surg, 51 (7), 1115-21
DOI 10.1016/j.jpedsurg.2015.12.007, PubMed 26787273

Kristensen V, Klepp P, Cvancarova M, Røseth A, Skar V, Moum B (2015)
Prediction of endoscopic disease activity in ulcerative colitis by two different assays for fecal calprotectin
J Crohns Colitis, 9 (2), 164-9
DOI 10.1093/ecco-jcc/jju015, PubMed 25518057

Kristensen V, Lauritzen T, Jelsness-JØrgensen LP, Moum B (2015)
Validation of a new extraction device for measuring faecal calprotectin in inflammatory bowel disease, and comparison to established extraction methods
Scand J Clin Lab Invest, 75 (5), 355-61
DOI 10.3109/00365513.2015.1030765, PubMed 25856663

Kristensen V, Malmstrøm GH, Skar V, Røseth A, Moum B (2015)
Clinical importance of faecal calprotectin variability in inflammatory bowel disease: intra-individual variability and standardisation of sampling procedure
Scand J Gastroenterol, 51 (5), 548-55
DOI 10.3109/00365521.2015.1117650, PubMed 26634305

Liaskou E, Klemsdal Henriksen EK, Holm K, Kaveh F, Hamm D, Fear J, Viken MK, Hov JR, Melum E, Robins H, Olweus J, Karlsen TH, Hirschfield GM (2015)
High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires
Hepatology, 63 (5), 1608-19
DOI 10.1002/hep.28116, PubMed 26257205

Lundin KE, Qiao SW, Snir O, Sollid LM (2015)
Coeliac disease - from genetic and immunological studies to clinical applications
Scand J Gastroenterol, 50 (6), 708-17
DOI 10.3109/00365521.2015.1030766, PubMed 25846940

Lundin KE, Wijmenga C (2015)
Coeliac disease and autoimmune disease-genetic overlap and screening
Nat Rev Gastroenterol Hepatol, 12 (9), 507-15
DOI 10.1038/nrgastro.2015.136, PubMed 26303674

Løvik A, Skodje G, Bratlie J, Brottveit M, Lundin KE (2015)
Diet adherence and gluten exposure in coeliac disease and self-reported non-coeliac gluten sensitivity
Clin Nutr, 36 (1), 275-280
DOI 10.1016/j.clnu.2015.11.017, PubMed 26714791

Olin P, Hausken J, Foss A, Karlsen TH, Melum E, Haugaa H (2015)
Continuous molecular adsorbent recirculating system treatment in 69 patients listed for liver transplantation
Scand J Gastroenterol, 50 (9), 1127-34
DOI 10.3109/00365521.2015.1027262, PubMed 25865318

Otterdal K, Haukeland JW, Yndestad A, Dahl TB, Holm S, Segers FM, Gladhaug IP, Konopski Z, Damås JK, Halvorsen B, Aukrust P (2015)
Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
Clin Transl Gastroenterol, 6, e95
DOI 10.1038/ctg.2015.23, PubMed 26133108

Snir O, Mesin L, Gidoni M, Lundin KE, Yaari G, Sollid LM (2015)
Analysis of celiac disease autoreactive gut plasma cells and their corresponding memory compartment in peripheral blood using high-throughput sequencing
J Immunol, 194 (12), 5703-12
DOI 10.4049/jimmunol.1402611, PubMed 25972486

Solberg IC, Høivik ML, Cvancarova M, Moum B, IBSEN Study Group (2015)
Risk matrix model for prediction of colectomy in a population-based study of ulcerative colitis patients (the IBSEN study)
Scand J Gastroenterol, 50 (12), 1456-62
DOI 10.3109/00365521.2015.1064991, PubMed 26139389

Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KE (2015)
Small bowel, celiac disease and adaptive immunity
Dig Dis, 33 (2), 115-21
DOI 10.1159/000369512, PubMed 25925911

Spada C, Stoker J, Alarcon O, Barbaro F, Bellini D, Bretthauer M, De Haan MC, Dumonceau JM, Ferlitsch M, Halligan S, Helbren E, Hellstrom M, Kuipers EJ, Lefere P, Mang T, Neri E, Petruzziello L, Plumb A, Regge D, Taylor SA, Hassan C, Laghi A (2015)
Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline
Eur Radiol, 25 (2), 331-45
DOI 10.1007/s00330-014-3435-z, PubMed 25278245

Steinsbø Ø, Dørum S, Lundin KE, Sollid LM (2015)
Serologic assay for diagnosis of celiac disease based on a patient-derived monoclonal antigliadin antibody
Gastroenterology, 149 (6), 1530-1540.e3
DOI 10.1053/j.gastro.2015.07.008, PubMed 26208894

Stiksrud B, Nowak P, Nwosu FC, Kvale D, Thalme A, Sonnerborg A, Ueland PM, Holm K, Birkeland SE, Dahm AE, Sandset PM, Rudi K, Hov JR, Dyrhol-Riise AM, Trøseid M (2015)
Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
J Acquir Immune Defic Syndr, 70 (4), 329-37
DOI 10.1097/QAI.0000000000000784, PubMed 26258571

Thorsen T, Dahlgren US, Aandahl EM, Grzyb K, Karlsen TH, Boberg KM, Rydberg L, Naper C, Foss A, Bennet W (2015)
Liver transplantation with deceased ABO-incompatible donors is life-saving but associated with increased risk of rejection and post-transplant complications
Transpl Int, 28 (7), 800-12
DOI 10.1111/tri.12552, PubMed 25736519

Vatn MH, Sandvik AK (2015)
Inflammatory bowel disease
Scand J Gastroenterol, 50 (6), 748-62
DOI 10.3109/00365521.2015.1033000, PubMed 25855003

Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
Hepatology, 62 (1), 188-97
DOI 10.1002/hep.27825, PubMed 25833813

Volta U, Caio G, De Giorgio R, Henriksen C, Skodje G, Lundin KE (2015)
Non-celiac gluten sensitivity: a work-in-progress entity in the spectrum of wheat-related disorders
Best Pract Res Clin Gastroenterol, 29 (3), 477-91
DOI 10.1016/j.bpg.2015.04.006, PubMed 26060112

Zahid W, Bergestuen D, Haugaa KH, Ueland T, Thiis-Evensen E, Aukrust P, Fosse E, Edvardsen T (2015)
Myocardial Function by Two-Dimensional Speckle Tracking Echocardiography and Activin A May Predict Mortality in Patients with Carcinoid Intestinal Disease
Cardiology, 132 (2), 81-90
DOI 10.1159/000431076, PubMed 26111973

Aabakken L (2015)
Scandinavian Journal of Gastroenterology - the editors-in-chief
Scand J Gastroenterol, 50 (6), 630-5
DOI 10.3109/00365521.2015.1028995, PubMed 25803744

 
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