Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Section of Preventive Medicine

24 publications found

Ben-Omran T, Masana L, Kolovou G, Ariceta G, Nóvoa FJ, Lund AM, Bogsrud MP, Araujo M, Hussein O, Ibarretxe D, Sanchez-Hernández RM, Santos RD (2019)
Real-World Outcomes with Lomitapide Use in Paediatric Patients with Homozygous Familial Hypercholesterolaemia
Adv Ther, 36 (7), 1786-1811
DOI 10.1007/s12325-019-00985-8, PubMed 31102204

Berlin I, Tonstad S (2019)
It's Time to Bury the "Smoker's Paradox"
Nicotine Tob Res, 21 (9), 1149-1150
DOI 10.1093/ntr/ntz106, PubMed 31231769

Bogsrud MP, Græsdal A, Johansen D, Langslet G, Hovland A, Arnesen KE, Mundal LJ, Retterstøl K, Wium C, Holven KB (2019)
LDL-cholesterol goal achievement, cardiovascular disease, and attributed risk of Lp(a) in a large cohort of predominantly genetically verified familial hypercholesterolemia
J Clin Lipidol, 13 (2), 279-286
DOI 10.1016/j.jacl.2019.01.010, PubMed 30910667

Charytan DM, Sabatine MS, Pedersen TR, Im K, Park JG, Pineda AL, Wasserman SM, Deedwania P, Olsson AG, Sever PS, Keech AC, Giugliano RP, FOURIER Steering Committee and Investigators (2019)
Efficacy and Safety of Evolocumab in Chronic Kidney Disease in the FOURIER Trial
J Am Coll Cardiol, 73 (23), 2961-2970
DOI 10.1016/j.jacc.2019.03.513, PubMed 31196453

Christensen JJ, Bakke SS, Ulven SM, Retterstøl K, Henriksen T, Bollerslev J, Espevik T, Aukrust P, Halvorsen B, Holven KB (2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children
Mol Nutr Food Res, 63 (7), e1800990
DOI 10.1002/mnfr.201800990, PubMed 30702198

Cwikiel J, Seljeflot I, Fagerland MW, Wachtell K, Arnesen H, Berge E, Flaa A (2019)
High-sensitive cardiac Troponin T and exercise stress test for evaluation of angiographically significant coronary disease
Int J Cardiol, 287, 1-6
DOI 10.1016/j.ijcard.2019.04.019, PubMed 31006595

Kjeldsen SE, Aksnes TA, Mo R, Klemsdal TO (2019)
Impact of the New ACC/AHA and ESC/ESH Hypertension Guidelines for Norway
Eur Heart J, 40 (19), 1485-1487
DOI 10.1093/eurheartj/ehz266, PubMed 31087051

Knudsen EC, Seljeflot I, Aksnes TA, Eritsland J, Arnesen H, Andersen GØ (2019)
IgM antibodies against phosphorylcholine measured early after acute ST-elevation myocardial infarction in relation to atherosclerotic disease burden and long-term clinical outcome
PLoS One, 14 (4), e0215640
DOI 10.1371/journal.pone.0215640, PubMed 31002684

Macpherson ME, Halvorsen B, Yndestad A, Ueland T, Mollnes TE, Berge RK, Rashidi A, Otterdal K, Gregersen I, Kong XY, Holven KB, Aukrust P, Fevang B, Jørgensen SF (2019)
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
Sci Rep, 9 (1), 9427
DOI 10.1038/s41598-019-45861-1, PubMed 31263122

Mehlum MH, Liestøl K, Wyller TB, Hua TA, Rostrup M, Berge E (2019)
Blood pressure variability in hypertensive patients with atrial fibrillation in the VALUE trial
Blood Press, 28 (2), 77-83
DOI 10.1080/08037051.2018.1524707, PubMed 30614275

Murphy SA, Pedersen TR, Gaciong ZA, Ceska R, Ezhov MV, Connolly DL, Jukema JW, Toth K, Tikkanen MJ, Im K, Wiviott SD, Kurtz CE, Honarpour N, Giugliano RP, Keech AC, Sever PS, Sabatine MS (2019)
Effect of the PCSK9 Inhibitor Evolocumab on Total Cardiovascular Events in Patients With Cardiovascular Disease: A Prespecified Analysis From the FOURIER Trial
JAMA Cardiol, 4 (7), 613-619
DOI 10.1001/jamacardio.2019.0886, PubMed 31116355

Müller-Wieland D, Rader DJ, Moriarty PM, Bergeron J, Langslet G, Ray KK, Manvelian G, Thompson D, Bujas-Bobanovic M, Roth EM (2019)
Efficacy and Safety of Alirocumab 300 mg Every 4 Weeks in Individuals with Type 2 Diabetes on Maximally Tolerated Statin
J Clin Endocrinol Metab (in press)
DOI 10.1210/jc.2018-02703, PubMed 31166599

Narverud I, Bogsrud MP, Øril LKL, Ulven SM, Retterstøl K, Ueland T, Mulder M, van Lennep JR, Halvorsen B, Aukrust P, Veierød MB, Holven KB (2019)
Lipoprotein (a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolemia
Br J Nutr, 1-24 (in press)
DOI 10.1017/S0007114519001600, PubMed 31262370

O'Donoghue ML, Fazio S, Giugliano RP, Stroes ESG, Kanevsky E, Gouni-Berthold I, Im K, Lira Pineda A, Wasserman SM, Češka R, Ezhov MV, Jukema JW, Jensen HK, Tokgözoğlu SL, Mach F, Huber K, Sever PS, Keech AC, Pedersen TR, Sabatine MS (2019)
Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk
Circulation, 139 (12), 1483-1492
DOI 10.1161/CIRCULATIONAHA.118.037184, PubMed 30586750

Qamar A, Giugliano RP, Keech AC, Kuder JF, Murphy SA, Kurtz CE, Wasserman SM, Sever PS, Pedersen TR, Sabatine MS (2019)
Interindividual Variation in Low-Density Lipoprotein Cholesterol Level Reduction With Evolocumab: An Analysis of FOURIER Trial Data
JAMA Cardiol, 4 (1), 59-63
DOI 10.1001/jamacardio.2018.4178, PubMed 30540337

Smiseth OA, Kjeldsen SE, Andersen OS, Mistry N, Westheim AS, Skulstad H, Gude E (2019)
Heart Failure with normal ejection fraction
Tidsskr. Nor. Laegeforen., 139 (6), 522-527

Smiseth OA, Kjeldsen SE, Andersen ØS, Mistry N, Westheim AS, Skulstad H, Gude E (2019)
Heart failure with preserved ejection fraction
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.18.0523, PubMed 30917641

Stokke IM, Li ZB, Cicala S, Okin PM, Kjeldsen SE, Devereux RB, Wachtell K (2019)
Association of left bundle branch block with new onset abnormal wall motion in treated hypertensive patients with left ventricle hypertrophy: the LIFE Echo Sub-study
Blood Press, 28 (2), 84-92
DOI 10.1080/08037051.2019.1569463, PubMed 30698038

Sundfør TM, Svendsen M, Heggen E, Dushanov S, Klemsdal TO, Tonstad S (2019)
BMI modifies the effect of dietary fat on atherogenic lipids: a randomized clinical trial
Am J Clin Nutr (in press)
DOI 10.1093/ajcn/nqz113, PubMed 31216575

Svendsen K, Jacobs DR, Røyseth IT, Garstad KW, Byfuglien MG, Granlund L, Mørch-Reiersen LT, Telle-Hansen VH, Retterstøl K (2019)
Community pharmacies offer a potential high-yield and convenient arena for total cholesterol and CVD risk screening
Eur J Public Health, 29 (1), 17-23
DOI 10.1093/eurpub/cky190, PubMed 30239673

Ulven SM, Holven KB, Gil A, Rangel-Huerta OD (2019)
Milk and Dairy Product Consumption and Inflammatory Biomarkers: An Updated Systematic Review of Randomized Clinical Trials
Adv Nutr, 10 (suppl_2), S239-S250
DOI 10.1093/advances/nmy072, PubMed 31089732

Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E et al. (2019)
[2018 ESC/ESH Guidelines for the management of arterial hypertension]
Kardiol Pol, 77 (2), 71-159
DOI 10.5603/KP.2019.0018, PubMed 30816983

Wisløff T, Mundal LJ, Retterstøl K, Igland J, Kristiansen IS (2019)
Economic evaluation of lipid lowering with PCSK9 inhibitors in patients with familial hypercholesterolemia: Methodological aspects
Atherosclerosis, 287, 140-146 (in press)
DOI 10.1016/j.atherosclerosis.2019.06.900, PubMed 31280039

Øyri LKL, Bogsrud MP, Kristiansen AL, Myhre JB, Retterstøl K, Brekke HK, Gundersen TE, Andersen LF, Holven KB (2019)
Infant cholesterol and glycated haemoglobin concentrations vary widely-Associations with breastfeeding, infant diet and maternal biomarkers
Acta Paediatr (in press)
DOI 10.1111/apa.14936, PubMed 31299108

 
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