Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2016 from OUS - Section of Preventive Medicine

40 publications found

Abou-Arab MH, Rostrup M, Heier T (2016)
Dose requirements of alfentanil to eliminate autonomic responses during rapid-sequence induction with thiopental 4 mg/kg and rocuronium 0.6 mg/kg
J Clin Anesth, 35, 465-474
DOI 10.1016/j.jclinane.2016.09.026, PubMed 27871575

Agca R, Heslinga SC, Rollefstad S, Heslinga M, McInnes IB, Peters MJ, Kvien TK, Dougados M, Radner H, Atzeni F, Primdahl J, Södergren A, Wallberg Jonsson S, van Rompay J, Zabalan C, Pedersen TR, Jacobsson L, de Vlam K, Gonzalez-Gay MA, Semb AG, Kitas GD, Smulders YM, Szekanecz Z, Sattar N, Symmons DP et al. (2016)
EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update
Ann Rheum Dis, 76 (1), 17-28
DOI 10.1136/annrheumdis-2016-209775, PubMed 27697765

Aune D, Keum N, Giovannucci E, Fadnes LT, Boffetta P, Greenwood DC, Tonstad S, Vatten LJ, Riboli E, Norat T (2016)
Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies
BMC Med, 14 (1), 207
DOI 10.1186/s12916-016-0730-3, PubMed 27916000

Aune D, Sen A, Norat T, Janszky I, Romundstad P, Tonstad S, Vatten LJ (2016)
Body Mass Index, Abdominal Fatness, and Heart Failure Incidence and Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies
Circulation, 133 (7), 639-49
DOI 10.1161/CIRCULATIONAHA.115.016801, PubMed 26746176

Bast-Pettersen R, Ulvestad B, Færden K, Clemm TA, Olsen R, Ellingsen DG, Nordby KC (2016)
Tremor and hand-arm vibration syndrome (HAVS) in road maintenance workers
Int Arch Occup Environ Health, 90 (1), 93-106
DOI 10.1007/s00420-016-1175-x, PubMed 27796506

Christensen JJ, Osnes L, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB (2016)
Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children
Data Brief, 10, 587-592
DOI 10.1016/j.dib.2016.12.042, PubMed 28070551

Christensen JJ, Osnes LT, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB (2016)
Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia
Atherosclerosis, 256, 67-74
DOI 10.1016/j.atherosclerosis.2016.11.031, PubMed 28024183

Christensen JJ, Retterstøl K, Godang K, Roland MC, Qvigstad E, Bollerslev J, Ueland T, Henriksen T, Holven KB (2016)
LDL cholesterol in early pregnancy and offspring cardiovascular disease risk factors
J Clin Lipidol, 10 (6), 1369-1378.e7
DOI 10.1016/j.jacl.2016.08.016, PubMed 27919354

Deedwania PC, Pedersen TR, DeMicco DA, Breazna A, Betteridge DJ, Hitman GA, Durrington P, Neil A, TNT, CARDS and IDEAL Steering Committees and Investigators (2016)
Differing predictive relationships between baseline LDL-C, systolic blood pressure, and cardiovascular outcomes
Int J Cardiol, 222, 548-556
DOI 10.1016/j.ijcard.2016.07.201, PubMed 27513651

EAS Familial Hypercholesterolaemia Studies Collaboration, Vallejo-Vaz AJ, Akram A, Kondapally Seshasai SR, Cole D, Watts GF, Hovingh GK, Kastelein JJ, Mata P, Raal FJ, Santos RD, Soran H, Freiberger T, Abifadel M, Aguilar-Salinas CA, Alnouri F, Alonso R, Al-Rasadi K, Banach M, Bogsrud MP, Bourbon M, Bruckert E, Car J, Ceska R, Corral P et al. (2016)
Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration
Atheroscler Suppl, 22, 1-32
DOI 10.1016/j.atherosclerosissup.2016.10.001, PubMed 27939304

Eskas PA, Heimark S, Mariampillai JE, Larstorp ACK, Elmula FEMF, Hoieggen A (2016)
Drug compliance and monitoring of antihypertensive treatment
Tidsskr. Nor. Laegeforen., 136 (10), 920-923

Eskås PA, Heimark S, Eek Mariampillai J, Larstorp AC, Fadl Elmula FE, Høieggen A (2016)
Adherence to medication and drug monitoring in apparent treatment-resistant hypertension
Blood Press, 25 (4), 199-205
DOI 10.3109/08037051.2015.1121706, PubMed 26729283

Fell AK, Abrahamsen R, Henneberger PK, Svendsen MV, Andersson E, Torén K, Kongerud J (2016)
Breath-taking jobs: a case-control study of respiratory work disability by occupation in Norway
Occup Environ Med, 73 (9), 600-6
DOI 10.1136/oemed-2015-103488, PubMed 27365181

Halvorsen B, Santilli F, Scholz H, Sahraoui A, Gulseth HL, Wium C, Lattanzio S, Formoso G, Di Fulvio P, Otterdal K, Retterstøl K, Holven KB, Gregersen I, Stavik B, Bjerkeli V, Michelsen AE, Ueland T, Liani R, Davi G, Aukrust P (2016)
LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
Diabetologia, 59 (10), 2134-44
DOI 10.1007/s00125-016-4036-y, PubMed 27421726

Hasvold P, Thuresson M, Sundström J, Hammar N, Kjeldsen SE, Johansson G, Holme I, Bodegård J (2016)
Association Between Paradoxical HDL Cholesterol Decrease and Risk of Major Adverse Cardiovascular Events in Patients Initiated on Statin Treatment in a Primary Care Setting
Clin Drug Investig, 36 (3), 225-33
DOI 10.1007/s40261-015-0372-9, PubMed 26718960

Heimark S, Eskås PA, Mariampillai JE, Larstorp AC, Høieggen A, Fadl Elmula FE (2016)
Tertiary work-up of apparent treatment-resistant hypertension
Blood Press, 25 (5), 312-8
DOI 10.3109/08037051.2016.1172865, PubMed 27124769

Ikdahl E, Rollefstad S, Hisdal J, Olsen IC, Pedersen TR, Kvien TK, Semb AG (2016)
Sustained Improvement of Arterial Stiffness and Blood Pressure after Long-Term Rosuvastatin Treatment in Patients with Inflammatory Joint Diseases: Results from the RORA-AS Study
PLoS One, 11 (4), e0153440
DOI 10.1371/journal.pone.0153440, PubMed 27093159

Kastelein JJ, Hovingh GK, Langslet G, Baccara-Dinet MT, Gipe DA, Chaudhari U, Zhao J, Minini P, Farnier M (2016)
Efficacy and safety of the proprotein convertase subtilisin/kexin type 9 monoclonal antibody alirocumab vs placebo in patients with heterozygous familial hypercholesterolemia
J Clin Lipidol, 11 (1), 195-203.e4
DOI 10.1016/j.jacl.2016.12.004, PubMed 28391886

Kjeldsen SE, Cha G, Villa G, Mancia G, DISTINCT Investigators (2016)
Nifedipine GITS/Candesartan Combination Therapy Lowers Blood Pressure Across Different Baseline Systolic and Diastolic Blood Pressure Categories: DISTINCT Study Subanalyses
J Clin Pharmacol, 56 (9), 1120-9
DOI 10.1002/jcph.712, PubMed 26829251

Kjeldsen SE, Dzongowski P, Li N, Wang L, Radlmaier A (2016)
Fixed-dose combination of nifedipine gastrointestinal therapeutic system and candesartan cilexetil in patients with moderate-to-severe essential hypertension: an open-label, long-term safety and efficacy study
J Clin Pharm Ther, 41 (6), 695-702
DOI 10.1111/jcpt.12451, PubMed 27670639

Langslet G, Breazna A, Drogari E (2016)
A 3-year study of atorvastatin in children and adolescents with heterozygous familial hypercholesterolemia
J Clin Lipidol, 10 (5), 1153-1162.e3
DOI 10.1016/j.jacl.2016.05.010, PubMed 27678432

Leiter LA, Langslet G, Vijapurkar U, Davies MJ, Canovatchel W (2016)
Simultaneous Reduction in Both HbA1c and Body Weight with Canagliflozin Versus Glimepiride in Patients with Type 2 Diabetes on Metformin
Diabetes Ther, 7 (2), 269-78
DOI 10.1007/s13300-016-0163-1, PubMed 26984361

Mancia G, Cha G, Gil-Extremera B, Harvey P, Lewin AJ, Villa G, Kjeldsen SE (2016)
Blood pressure-lowering effects of nifedipine/candesartan combinations in high-risk individuals: subgroup analysis of the DISTINCT randomised trial
J Hum Hypertens, 31 (3), 178-188
DOI 10.1038/jhh.2016.54, PubMed 27511476

Mansoor N, Vinknes KJ, Veierød MB, Retterstøl K (2016)
Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials
Br J Nutr, 115 (3), 466-79
DOI 10.1017/S0007114515004699, PubMed 26768850

Masefield S, Powell P, Jiménez-Ruiz C, Hajek P, Lewis K, Andreas S, Tønnesen P, van Schayck O, Gratziou C, Dautzenberg B, Tonstad S, Hering T, Nardini S, Fletcher M (2016)
Recommendations to improve smoking cessation outcomes from people with lung conditions who smoke
ERJ Open Res, 2 (2)
DOI 10.1183/23120541.00009-2016, PubMed 27730185

Mundal L, Igland J, Ose L, Holven KB, Veierød MB, Leren TP, Retterstøl K (2016)
Cardiovascular disease mortality in patients with genetically verified familial hypercholesterolemia in Norway during 1992-2013
Eur J Prev Cardiol, 24 (2), 137-144
DOI 10.1177/2047487316676135, PubMed 27794106

Mundal L, Retterstøl K (2016)
A systematic review of current studies in patients with familial hypercholesterolemia by use of national familial hypercholesterolemia registries
Curr Opin Lipidol, 27 (4), 388-97
DOI 10.1097/MOL.0000000000000300, PubMed 27070076

Mundal L, Veierød MB, Halvorsen T, Holven KB, Ose L, Iversen PO, Tell GS, Leren TP, Retterstøl K (2016)
Cardiovascular disease in patients with genotyped familial hypercholesterolemia in Norway during 1994-2009, a registry study
Eur J Prev Cardiol, 23 (18), 1962-1969
DOI 10.1177/2047487316666371, PubMed 27558979

Nordstrom M, Paus B, Retterstol K, Kolset SO (2016)
The prevalence of metabolic risk factors of atherosclerotic cardiovascular disease in Williams syndrome, Prader-Willi syndrome, and Down syndrome
J. Intellect. Dev. Dis., 41 (3), 187-196

Okin PM, Kjeldsen SE, Devereux RB (2016)
Impact of achieved systolic blood pressure on renal function in hypertensive patients
Eur Heart J Qual Care Clin Outcomes, 2 (4), 271-276
DOI 10.1093/ehjqcco/qcw017, PubMed 29474712

Ottestad I, Nordvi B, Vogt G, Holck M, Halvorsen B, Brønner KW, Retterstøl K, Holven KB, Nilsson A, Ulven SM (2016)
Bioavailability of n-3 fatty acids from n-3-enriched foods and fish oil with different oxidative quality in healthy human subjects: a randomised single-meal cross-over study
J Nutr Sci, 5, e43
DOI 10.1017/jns.2016.34, PubMed 28620470

Palatini P, Rosei EA, Casiglia E, Chalmers J, Ferrari R, Grassi G, Inoue T, Jelakovic B, Jensen MT, Julius S, Kjeldsen SE, Mancia G, Parati G, Pauletto P, Stella A, Zanchetti A (2016)
Management of the hypertensive patient with elevated heart rate: Statement of the Second Consensus Conference endorsed by the European Society of Hypertension
J Hypertens, 34 (5), 813-21
DOI 10.1097/HJH.0000000000000865, PubMed 26982382

Pedersen TR (2016)
The Success Story of LDL Cholesterol Lowering
Circ Res, 118 (4), 721-31
DOI 10.1161/CIRCRESAHA.115.306297, PubMed 26892969

Pingitore P, Lepore SM, Pirazzi C, Mancina RM, Motta BM, Valenti L, Berge KE, Retterstøl K, Leren TP, Wiklund O, Romeo S (2016)
Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia
J Clin Lipidol, 10 (4), 816-823
DOI 10.1016/j.jacl.2016.02.015, PubMed 27578112

Roth EM, Moriarty PM, Bergeron J, Langslet G, Manvelian G, Zhao J, Baccara-Dinet MT, Rader DJ, ODYSSEY CHOICE I investigators (2016)
A phase III randomized trial evaluating alirocumab 300 mg every 4 weeks as monotherapy or add-on to statin: ODYSSEY CHOICE I
Atherosclerosis, 254, 254-262
DOI 10.1016/j.atherosclerosis.2016.08.043, PubMed 27639753

Sikkeland L, Alexis NE, Fry RC, Martin E, Danielsen TE, Søstrand P, Kongerud J (2016)
Inflammation in induced sputum after aluminium oxide exposure: an experimental chamber study
Occup Environ Med, 73 (3), 199-205
DOI 10.1136/oemed-2015-103254, PubMed 26786756

Søstrand P, Sverre L, Danielsen TE (2016)
100 kBq m-3 Radon Activity Concentration in the Atmosphere of a Bathroom Supplied with Groundwater From A Gneissic Rock Area with Consanguineous Intrusions
Health Phys, 111 (6), 559-561
DOI 10.1097/HP.0000000000000568, PubMed 27798479

Tonstad S, Lawrence D (2016)
Varenicline in smokers with diabetes: A pooled analysis of 15 randomized, placebo-controlled studies of varenicline
J Diabetes Investig, 8 (1), 93-100
DOI 10.1111/jdi.12543, PubMed 27223809

Torvik K, Narverud I, Ottestad I, Svilaas A, Gran JM, Retterstøl K, Ellingvåg A, Strøm E, Ose L, Veierød MB, Holven KB (2016)
Dietary counseling is associated with an improved lipid profile in children with familial hypercholesterolemia
Atherosclerosis, 252, 21-27
DOI 10.1016/j.atherosclerosis.2016.07.913, PubMed 27494447

Ulvestad B, Randem BG, Skare Ø, Aaløkken TM, Myranek GK, Elihn K, Lund MB (2016)
Lung function in asphalt pavers: a longitudinal study
Int Arch Occup Environ Health, 90 (1), 63-71
DOI 10.1007/s00420-016-1173-z, PubMed 27722781

 
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