Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Psychosis Research (NORMENT)

26 publications found

Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Steen NE, Aukrust P, Andreassen OA, Szabo A, Djurovic S (2020)
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun (in press)
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548

Bahrami S, Steen NE, Shadrin A, O'Connell K, Frei O, Bettella F, Wirgenes KV, Krull F, Fan CC, Dale AM, Smeland OB, Djurovic S, Andreassen OA (2020)
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
JAMA Psychiatry (in press)
DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414

Córdova-Palomera A, van der Meer D, Kaufmann T, Bettella F, Wang Y, Alnæs D, Doan NT, Agartz I, Bertolino A, Buitelaar JK, Coynel D, Djurovic S, Dørum ES, Espeseth T, Fazio L, Franke B, Frei O, Håberg A, Le Hellard S, Jönsson EG, Kolskår KK, Lund MJ, Moberget T, Nordvik JE, Nyberg L et al. (2020)
Genetic control of variability in subcortical and intracranial volumes
Mol Psychiatry
DOI 10.1038/s41380-020-0664-1, PubMed 32047264

de Lange AG, Cole JH (2020)
Commentary: Correction procedures in brain-age prediction
Neuroimage Clin, 26, 102229 (in press)
DOI 10.1016/j.nicl.2020.102229, PubMed 32120292

Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR et al. (2020)
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296

Gurholt TP, Haukvik UK, Lonning V, Jönsson EG, Pasternak O, Agartz I (2020)
Microstructural White Matter and Links With Subcortical Structures in Chronic Schizophrenia: A Free-Water Imaging Approach
Front Psychiatry, 11, 56
DOI 10.3389/fpsyt.2020.00056, PubMed 32180735

Hammar Å, Semkovska M, Borgen IMH, Myklebost S, Ronold EH, Sveen T, Ueland T, Porter R, Johnson SL (2020)
A pilot study of cognitive remediation in remitted major depressive disorder patients
Appl Neuropsychol Adult
DOI 10.1080/23279095.2020.1726919, PubMed 32088993

Hauger LE, Westlye LT, Bjørnebekk A (2020)
Anabolic androgenic steroid dependence is associated with executive dysfunction
Drug Alcohol Depend, 208, 107874
DOI 10.1016/j.drugalcdep.2020.107874, PubMed 31972519

Hilland E, Landrø NI, Harmer CJ, Browning M, Maglanoc LA, Jonassen R (2020)
Attentional bias modification is associated with fMRI response toward negative stimuli in individuals with residual depression: a randomized controlled trial
J Psychiatry Neurosci, 45 (1), 23-33
DOI 10.1503/jpn.180118, PubMed 31397551

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2020)
Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 52 (3), 354
DOI 10.1038/s41588-019-0573-x, PubMed 32029921

Juvodden HT, Viken MK, Nordstrand SEH, Viste R, Westlye LT, Thorsby PM, Lie BA, Knudsen-Heier S (2020)
HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives
Sleep, 43 (3)
DOI 10.1093/sleep/zsz239, PubMed 31606740

Lam M, Awasthi S, Watson HJ, Goldstein J, Panagiotaropoulou G, Trubetskoy V, Karlsson R, Frei O, Fan CC, De Witte W, Mota NR, Mullins N, Brügger K, Lee SH, Wray NR, Skarabis N, Huang H, Neale B, Daly MJ, Mattheisen M, Walters R, Ripke S (2020)
RICOPILI: Rapid Imputation for COnsortias PIpeLIne
Bioinformatics, 36 (3), 930-933
DOI 10.1093/bioinformatics/btz633, PubMed 31393554

Lyngstad SH, Bettella F, Aminoff SR, Athanasiu L, Andreassen OA, Faerden A, Melle I (2020)
Associations between schizophrenia polygenic risk and apathy in schizophrenia spectrum disorders and healthy controls
Acta Psychiatr Scand (in press)
DOI 10.1111/acps.13167, PubMed 32091622

Lyngstad SH, Gardsjord ES, Engen MJ, Haatveit B, Ihler HM, Wedervang-Resell K, Simonsen C, Melle I, Færden A (2020)
Trajectory and early predictors of apathy development in first-episode psychosis and healthy controls: a 10-year follow-up study
Eur Arch Psychiatry Clin Neurosci (in press)
DOI 10.1007/s00406-020-01112-3, PubMed 32130475

Meijer M, Klein M, Hannon E, van der Meer D, Hartman C, Oosterlaan J, Heslenfeld D, Hoekstra PJ, Buitelaar J, Mill J, Franke B (2020)
Genome-Wide DNA Methylation Patterns in Persistent Attention-Deficit/Hyperactivity Disorder and in Association With Impulsive and Callous Traits
Front Genet, 11, 16
DOI 10.3389/fgene.2020.00016, PubMed 32082368

Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA et al. (2020)
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
Addict Biol, e12880
DOI 10.1111/adb.12880, PubMed 32064741

Nardai S, László M, Szabó A, Alpár A, Hanics J, Zahola P, Merkely B, Frecska E, Nagy Z (2020)
N,N-dimethyltryptamine reduces infarct size and improves functional recovery following transient focal brain ischemia in rats
Exp Neurol, 327, 113245
DOI 10.1016/j.expneurol.2020.113245, PubMed 32067950

Richards AL, Pardiñas AF, Frizzati A, Tansey KE, Lynham AJ, Holmans P, Legge SE, Savage JE, Agartz I, Andreassen OA, Blokland GAM, Corvin A, Cosgrove D, Degenhardt F, Djurovic S, Espeseth T, Ferraro L, Gayer-Anderson C, Giegling I, van Haren NE, Hartmann AM, Hubert JJ, Jönsson EG, Konte B, Lennertz L et al. (2020)
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
Schizophr Bull, 46 (2), 336-344
DOI 10.1093/schbul/sbz061, PubMed 31206164

Smeland OB, Shadrin A, Bahrami S, Broce I, Tesli M, Frei O, Wirgenes KV, O'Connell KS, Krull F, Bettella F, Steen NE, Sugrue L, Wang Y, Svenningsson P, Sharma M, Pihlstrøm L, Toft M, O'Donovan M, Djurovic S, Desikan R, Dale AM, Andreassen OA (2020)
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043

Smelror RE, Rund BR, Lonning V, Jørgensen KN, Wedervang-Resell K, Andreassen OA, Ueland T, Myhre AM, Agartz I (2020)
Negative and disorganized symptoms mediate the relationship between verbal learning and global functioning in adolescents with early-onset psychosis
Eur Child Adolesc Psychiatry
DOI 10.1007/s00787-020-01479-7, PubMed 32036438

Tesli N, van der Meer D, Rokicki J, Storvestre G, Røsæg C, Jensen A, Hjell G, Bell C, Fischer-Vieler T, Tesli M, Andreassen OA, Melle I, Agartz I, Haukvik UK (2020)
Hippocampal subfield and amygdala nuclei volumes in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci
DOI 10.1007/s00406-020-01098-y, PubMed 31980898

Thompson PM, Jahanshad N, Ching CRK, Salminen LE, Thomopoulos SI, Bright J, Baune BT, Bertolín S, Bralten J, Bruin WB, Bülow R, Chen J, Chye Y, Dannlowski U, de Kovel CGF, Donohoe G, Eyler LT, Faraone SV, Favre P, Filippi CA, Frodl T, Garijo D, Gil Y, Grabe HJ, Grasby KL et al. (2020)
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Transl Psychiatry, 10 (1), 100
DOI 10.1038/s41398-020-0705-1, PubMed 32198361

Vaskinn A, Horan WP (2020)
Social Cognition and Schizophrenia: Unresolved Issues and New Challenges in a Maturing Field of Research
Schizophr Bull (in press)
DOI 10.1093/schbul/sbaa034, PubMed 32133507

Voldsbekk I, Maximov II, Zak N, Roelfs D, Geier O, Due-Tønnessen P, Elvsåshagen T, Strømstad M, Bjørnerud A, Groote I (2020)
Evidence for wakefulness-related changes to extracellular space in human brain white matter from diffusion-weighted MRI
Neuroimage, 212, 116682 (in press)
DOI 10.1016/j.neuroimage.2020.116682, PubMed 32114147

Watanabe K, Stringer S, Frei O, Mirkov MU, de Leeuw C, Polderman TJC, van der Sluis S, Andreassen OA, Neale BM, Posthuma D (2020)
Author Correction: A global overview of pleiotropy and genetic architecture in complex traits
Nat Genet, 52 (3), 353
DOI 10.1038/s41588-019-0571-z, PubMed 32029922

Werner MCF, Wirgenes KV, Haram M, Bettella F, Lunding SH, Rødevand L, Hjell G, Agartz I, Djurovic S, Melle I, Andreassen OA, Steen NE (2020)
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
Schizophr Res (in press)
DOI 10.1016/j.schres.2020.03.006, PubMed 32171635

 
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